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The role of immune system in autism
Niederlová, Veronika ; Otáhal, Jakub (advisor) ; Hájková, Michaela (referee)
Autism is a complex neurodevelopmental disorder with yet unknown etiology. The research point out abnormalities in the immune system of pacients with autism, which could be related to the development of the disease. This thesis reviews current scientific knowledge about the role of the immune system in the development of autism. The leading chapters include family history of autoimmune diseases, specific HLA alleles, the most common autoantibodies and maternal antibodies, lowered NK cell activity and cytokine levels in pacients with autism. Powered by TCPDF (www.tcpdf.org)
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Helping Autistic Childern In The APLA Institution
Kouklíková, Monika ; Poláčková, Jana (advisor) ; Cintlová, Jitka (referee)
This bachelor thesis includes basic findings concerning Disorders from autistic spectrum. Theoretical part is divided into eight chapters. Following chapters describe NAUTIS organisation per se and case reports compiled and based on discussions. In the theoretical part I explained what means Disorders from autistic spectrum. It follows by history, ethology and Disorders from autistic spectrum. Furthermore analysis of each individual disorder, which should elucidate symptoms and behavior of people with Disorders from autistic spectrum. In the end of the theoretical part, the bachelor thesis is aboutdemography, organisations and legislativ impact. Practical part is compiled from cases based on discussions with families, where I work as an personal assistant. I work with the families more than a year and they were willing to cooperate with me.
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Possible causes of the increase of autism
Tomašovičová, Katarína ; Niederlová, Markéta (advisor) ; Draberová, Jana (referee)
This paper focuses on depicting potential causes of the increase in autism. The theoretical part includes a definition of autism, a historical development in the understanding of autism, a development of diagnostic criteria and their potential effect on autism prevalence. The differences between the global classification systems ICD and DSM are also described. Later, the difficulty of ASD diagnosis alone is discussed. The next section presents views on the etiology of autism which are divided into etiology on psychological basis, etiology based on genotype, and environmental etiology, according to operating factors. The last chapter of the theoretical part is for clarity devoted to the summary of the possible causes of the increase in autism. A research proposal which deals with advanced parental age as a risk factor of autism is also a part of the paper.
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Editing, validation, standardization and preparation for publication of electronic version of an screening diagnostic questionnaire DACH
Šporclová, Veronika ; Niederlová, Markéta (advisor) ; Šípek, Jiří (referee) ; Thorová, Kateřina (referee)
The questionnaire DACH was created within the pilot survey of the dissertation project of PhDr. Kateřina Thorová, Ph.D. Since it was put into practice, the questionnaire has become a relatively common tool used in the diagnosis of Autism Spectrum Disorders. The theoretical section of my dissertation introduces the reader to the wider context of Autism Spectrum Disorders - from ethiology to treatment (therapy). The empirical section then focuses on editing, validation and standardization of the DACH questionnaire created by Thorová. Empirical testing of the DACH was conducted on a sample of 240 people. Statistical analysis of the collected data demonstrated a relatively high level of reliability, sensitivity and specificity of the method, along with a high predictive value of positive results. The correlation between the questionnaire results and the results of the diagnostic assessment with the use of the methods of the "golden standard" for autism was lower, but can be considered as satisfactory. The main goal of my dissertation is to develop a standardized Czech method for screening early symptoms of autism in children. For wider access of the practical applications of this project, an electronic version of the DACH questionnaire is available, including scoring and general recommendations. The...
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Use of cognitive behavioural therapy for individuals with autistic spectrum disorders
Macháčková, Milada ; Felcmanová, Lenka (advisor) ; Hájková, Vanda (referee)
In my thesis I describe the application of cognitive behavioral therapy (CBT) to patients with autism-spectrum disorders (ASD), with special attention to the social aspects of this pervasive developmental disorder. Social ineptitude, bad orientation in relationships, reserved behaviour and similar characteristics are typical of ASD, but it does not necessarily follow that an individual who has difficulties to enter into relationships does not desire to do so. These days, CBT enters this system as one of a few demonstrably effective methods. As the theoretical background for the thesis I present CBT as a school of psychotherapy, with its history and current development. Further, I characterize ASD and present the section of the spectrum in which CBT will be used the most. The practical part will present the application of CBT to a client with Asperger syndrome.
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Influence and use of art education on the development of mental and social skills, knowledge and habits of children diagnosed with autism
Bejšovcová, Jitka ; Pfeiffer, Jan (advisor) ; Fišerová, Zuzana (referee)
Title of bachelor work: Influence and use of art education on the development of mental and social skills, knowledge and habits of children diagnosed with autism Abstract The bachelor thesis named "The use and impact of art education on the development of mental and social skills, knowledge and habits of children diagnosed with autism" is elaborated as a participatory probe where the core is the analysis of artistic tasks for pupils with autistic spectrum disorders, with a focus on analyzing the impact of creative duties on development of key competencies in accordance with RVP and individual IVP, drawn up for each individual student, in collaboration with SPC Most. The thesis contains a set of individual artistic tasks, the methodology used to work on individual activities, analysis of the impact of activities to develop the skills, knowledge and habits of students, documentation and critical evaluation of a series of creative tasks and results of the probe.
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