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Possibility of pedagogical support for two pupils of younger school age in physical education at an alternative school.
Vyvialová, Kristýna ; Pavlová, Ilona (advisor) ; Kotlík, Kamil (referee)
Title: Possibility of pedagogical support for two pupils of younger school age in physical education at an alternative school. Objectives: The aim of the work is to explore the possibilities of pedagogical support in the framework of physical education for two pupils with special educational needs at the Waldorfská Jinonice primary school. Methods: The thesis is based on the theoretical-empirical methods. The research consisted of two pupils with SVP. This was a girl and a boy aged 9. The intervention consisted of diagnosis, the creation of an individual training plan and the follow-up of pupils for one month. There were 8 exercise unit in total at the Waldorf Jinonice Primary School. Results: After a month, the creation and fulfilment of IVP proved to have a positive effect on the motor skills of children at the Waldorf School. Using the MABC-2 test battery. I found that both girls and boys had improvements in balance, aiming and catching as well as manual skills. Keywords: IVP - individual training plan, MABC-2 test battery, SVP - special educational needs, epilepsy, ADHD - attention deficit hyperactivity disorder, visual impairment, Waldorf School.
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The influence of epilepsy on the activities of daily life for children
Konečná, Eliška ; Nikodemová, Hana (advisor) ; Tomová, Šárka (referee)
The bachelor's thesis on the topic "Influence of epilepsy on the activities of children's daily life" is focused on the daily activities of children with epilepsy. Epilepsy as a disease is a relatively common diagnosis, which to some extent affects the lives not only of patients but also of their immediate surroundings. The aim of this bachelor thesis was to find out and map how children in the younger school age range to adolescents with epilepsy are limited in everyday activities. In the theoretical part of the work, attention is paid to existing knowledge about the problem of the disease, its causes, symptoms, diagnosis and treatment. Furthermore, the quality of life, where this concept is defined and the definition of the concept of daily activity. To obtain data, a questionnaire of our own creation was created, focusing on daily activities. The questionnaire contains a total of 26 items, to which the respondents answered individual questions, which were then analyzed and evaluated. The empirical part contains goals, working hypotheses, methodology and organization of the survey, characteristics and description of the examined sample. There is a presentation of the results of a questionnaire survey, which was attended by 44 respondents, the survey itself took place with the prior agreement of the legal...
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Causes of epilepsy due to disorders of cortical development of the brain
Populová, Jana ; Řehořová, Monika (advisor) ; Růžička, Jiří (referee)
Malformation of cortical development are an important cause of childhood epilepsy. It is estimated that up to 40% of these cases are medication-resistant. Pathophysiological mechanisms involved in the development of epilepsy are unknown. Identification of new type of genes associated with MCD leads to development of new experimental models recapilute human clinical symptoms. Aim of this study is to summarize information on current progress in this area obtained from MCD experimental models. These informations will help us better understand epileptogenesis. Keywords: malformation of cortical development, epilepsy, focal cortical dysplasia, epileptogenesis
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Neural and Genetic Basis of Epilepsy
Figelová, Tereza ; Ehler, Edvard (advisor) ; Pavlasová, Lenka (referee)
This thesis describes neural and genetic basis of epilepsy, addresses the distribution of epileptic sezuries, which genes affect epilepsy and the connection between epilepsy and the nervous system. The thesis is based on data collection from scientific books, partly from data published by hospitals. Its focus is getting from the general expressions to the cellular level of the problem, which is necessary to clarify the epileptic principles. It also deals with the genetic nature of epilepsy, as it is with the inheritance of the disease and deals in more detail with early infantile epileptic. The beginning of work is about basic information of epilepsy. Next, it looks into the mechanisms that influence the emergence of epilepsy. Continues to look at the structures in the brain associated with epilepsy. And at the end, it deels with genetic nature of epilepsy. A brochure was created for this work, where basic information about epilepsy can be found, first aid for an epileptic seizure and early infantile epileptic encephalopathy is discussed in paragraphs.
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The quality of life in patients with epilepsy
Duchoň, Jan ; Javůrková, Alena (advisor) ; Jirkovský, Daniel (referee)
Background: The bachelor's thesis deals with the subjective assessment of the quality of life in people with epilepsy by the screening questionnaire Patient Weighted Quality Of Life In Epilepsy Inventory (QOLIE-10-P) in the Czech Republic. Objectives: The aim of this quantitative study was to assess the psychometric properties of the Czech version of the QOLIE-10-P questionnaire, to validate it on a sample of patients in the Czech Republic, to assess the influence of individual sociodemo- graphic and clinical variables on the quality of life of these patients, to determine, which of these variables predict quality of life and perform McCall's area transformation of Mean score and Final score QOLIE-10-P for clinical screening use in nursing practice. Methods: The study population comprised 608 patients from the Center for Epilepsy of the Neurological Department 2nd Medical Faculty Charles University and the Motol University Hospital, who met inclusive and exclusive criteria. All patients underwent neurological and neuropsychological examination and a QOLIE-10-P questionnaire was administered to them. For statistical data processing were used parametric and non- parametric tests, determination of internal consistency, test-retest reliability, factor analysis, linear regression and multiregression...
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Human in vitro models for epilepsy research
Hebenstreitová, Kristýna ; Danačíková, Šárka (advisor) ; Valeš, Karel (referee)
Epilepsy is the most common chronic neurological disease that affects around 1 % of the world population. It is a multifactorial disease, which is characterised by recurrent seizures. Present pharmacological treatment is symptomatic and approximately one third of the patients develop pharmacorezistant epilepsy. This bachelor thesis presents an overview of current knowledge about the modelling of epilepsy, while focusing on human in vitro models. Cell lines appear to be very promising in vitro models for modelling genetic epilepsies. For example, cell lines derived from human induced pluripotent stem cells or human neural stem cells, which both allow for introduction of potentially pathological mutations and further differentiation into many different cell types. Human in vitro models of epilepsy play important role in understanding the process of epileptogenesis, ictogenesis, mechanism of antiepileptic drugs effects and are used in the search for new active substances. Epilepsy comes with great burden of disease for the patients, that is why it is very important to research not only the molecular mechanisms of epileptogenesis, but also advancements of personalised therapy, which could give hope to many (even pharmacorezistant) patients.
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Attitudes of parents and teachers in the education of a pupil with a chronic disease at the 1 st stage of a regular primary school
Vopatová, Kristina ; Zulić, Marija (advisor) ; Hájková, Vanda (referee)
The diploma thesis deals with the attitude of parents and teachers of pupils with chronic diseases in the attenuation of compulsory school attendance at the 1st stage of ordinary primary school. The objective of the work is to identify the problems that parents and teachers of chronically ill students encounter during the educational process. From this basis, the purpose is also to find the basis for the best possible cooperation between parents and teachers. The theoretical idea is represented by individual chronic diseases, namely asthma, cystic fibrosis, pediatric oncological diseases, type 1 diabetes mellitus and epilepsy. In addition, the legislative framework for the education of pupils with these diseases, the methodology of working with pupils with chronic diseases and a search of domestic and foreign research conducted on a similar topic are addressed. The methodological part is devoted to qualitative research, the main goal of which is to find out the attitudes of teachers and parents to the educational process of pupils suffering from the above diseases. Using a questionnaire survey and a semi-structured interview, it is ascertained what are the attitudes of parents and teachers towards the education of pupils with the above-mentioned types of chronic diseases in ordinary primary school....
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Cortical-subcortical interactions in EEG data of patients with pharmacoresistant epilepsy
Šíma, Jan ; Králík, Martin (referee) ; Lamoš, Martin (advisor)
This bachelor's thesis deals with the elaboration of a literature search on epilepsy and electroencephalography signals with a focus on patients with drug-resistant epilepsy and the analysis of cortico-subcortical relationships. The theoretical part describes the chapters of epilepsy, electroencephalography, the possibility of pre-processing EEG data and analytical methods, which describe the cortico-subcortical interactions. The practical part contains pre-processing of EEG data, analysis of methods used, data analysis, results, discussion, and conclusion. The data analysis itself is performed by the Phase-amplitude coupling method. The discussion discusses the results, limitations, and other possible connections. The conclusion summarizes the whole bachelor thesis.
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Epilepsy impact on quality of life in women
Prudnikova, Elizaveta ; Lustigová, Michala (advisor) ; Špačková, Petra (referee)
This thesis looks into the concept of the quality of life in women with epilepsy from a qualitative perspective. Epilepsy, as is a chronic neurological disease, affects not only everyday activities after the diagnosis, but also has its impact on the women's life regarding employment or family. By adapting the narrative analysis this thesis categorizes the influential factors of this concept into primary and secondary ones. Moreover, it explores in detail the issue of obtaining a driving license, which is one of the specifics of the people with epilepsy in Czechia. Also, it defines the respondents' attitudes toward the societal perception of epilepsy and fears that accompany it. In addition to that, the matter of motherhood and pregnancy for women with epilepsy is explored as one of the influential factors of the quality of life. Lastly, this thesis argues that the qualitative approach is essential for the initial examination of the selected sample for future investigations regarding the concept of the quality of life in epilepsy.
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Effects of a neuroactive steroid on motor skills of young laboratory rat.
Košťálová, Tereza ; Mareš, Pavel (advisor) ; Valeš, Karel (referee)
The steroid substances with effect on nervous tissue are plenteously studied in last years. Their biggest benefits are especially anticonvulsant and anxiolytic effects. This thesis inspects the influence of newly discovered neruactive steroid pregnanolone pyroglutamate synthesized in The Institute of Organic Chemistry and Biochemistry of the Czech Academy of Science (IOCB CAS), which offer potential opportunity of a new therapy of epilepsy from actual pharmacokinetic results. Our goal was to detect, if this substance has any negative effects on locomotor skills of young laboratory rats. In theoretical part of the thesis the development of laboratory rat is briefly descibed, especially its motor skills and sensory functions in comparison with human. The process of the experiments and choice of especially motor skill tests are described in Metogology part. The results of experiment and its comparation with the effect of other neuromediators are introduced and discussed in the practical part of this thesis. There were no serious effects of pregnanolonepyroglutamate applied repeatedly in perinatal period on motor performance. Acute administration of the highest dose of PPG to 12-day-old rat pups resulted in prolongation of time in surface righting and negative geotxis tests. This data are positive for...
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