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The firm strategy project of the company Gentech, s. r. o.
Pulkrabová, Magdalena ; Šlechtová, Jitka (advisor) ; Švecová, Lenka (referee)
The aim of this thesis is (i) the introduction of the small company Gentech, s. r. o., which operates in building industry, (ii) the assessment of its current activities, (iii) the internal analysis of the firm, (iv) the analysis of the firm's industry and (v) the external macroenvironment (PEST) analysis. The internal analysis identified the firm's strengths and weaknesses and the external analysis revealed opportunities and threats. A profile of the strengths, weaknesses, opportunities, and threats were generated by means of a SWOT analysis. An industry analysis was performed using a framework developer by M. E. Porter known as Porter's five forces. On the bases of the information from the environmental scan, they were outlined possibility options for the firm strategy which should be necessary for this small company to survive and prosper.
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The brain infarct core delineation using computed tomography angiography source images in acute stroke patients
Rohan, Vladimír ; Choc, Milan (advisor) ; Kalvach, Pavel (referee) ; Kalita, Zbyněk (referee) ; Smrčka, Martin (referee)
Background and Purpose: Ischemic stroke is the 3rd most common cause of death and most common cause of permanent disability in developed countries. Rapid diagnostic work-up with reliable assessment of infarcted brain tissue and potentionally salvageable brain tissue is critical for acute stroke management. The first aim of this study is to asses delineation of infarct core in acute stroke patients using whole brain perfused blood volume (PBV) maps. These maps are calculated by automatic processing from computed tomography angiography source images (CTA-SI) and non-contrast computed tomography (NCCT) data. The second aim is to determine optimal quantitative threshold of PBV for infarct core identification in acute stroke setting. Material and methods: PBV maps were constructed using prototype software from NCCT and CTA-SI data in 37 acute ischemic stroke patients with angiographically proved recanalization after intravenous thrombolytic treatment. These PBV maps were automatically compared with final infarct extension on follow-up NCCT. The anatomic pixel-by-pixel correlation was assessed using Matthew's correlation coefficient (MCC) for infarct core delineation using different critical values of PBV. The optimal threshold with the best correlation was used for infarct volume computation. Minimal PBV...
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EFFECT OF GEOMETRICAL PRECISION MACHINING CENTERS ON THE DESIRED CHARAKTERISTICTS OF THE GOODS
Holub, Michal ; Demeč, Peter (referee) ; Hýbner, Břetislav (referee) ; Pernikář, Jiří (referee) ; Marek, Jiří (advisor)
The main subject of this doctoral thesis is the influence of the geometrical accuracy of large CNC machine tools on desired features of produced work pieces. Doe to globalized market environment and competition producers of machine tools have changed their strategy for delivery of their products to customers. The main issue is not only to deliver a machine tool as such; supporting instructions related to the technology of the cutting process on the machine tool are of great importance. When taking delivery, the customer can see a new machine tool that will produce by him specified work piece with a desired accuracy. In the proposed thesis, a development of a novel methodology of measuring vertical lathes for prediction of chosen geometrical parameters of work pieces is introduced. The main goal of this work has been to determine the influence of the geometrical accuracy of selected design groups of a vertical lath on the future geometric accuracy of the work piece. The proposed methodology has been developed and verified on a selected vertical lath SKIQ30 produced by TOSHULIN, a.s. For identification of chosen parameters of the vertical lath a measuring system using latest measuring technologies has been applied. The basic tool for measured data processing has been a set of statistic methods for prediction of behaviour of measured design groups of the machine. The foundation for statistical processing has been calculation of geometrical deviations obtained from algorithms designed for proposed measurement methodology. The proposed measurement methodology for vertical lathes has been divided into two parts. In the first part, the methodology of measurement and evaluation of linear axes is solved, where a measuring system Laser Track has been used. The employment of the system Laser Track turned out to be very suitable. Conclusions related to the accuracy of the measuring device have been drawn in the thesis. The second part of the proposed methodology is represented by observation and description of the rotating disk, where non-contact position transducers have been used. In the course of the doctoral dissertation it has been observed that the studied (with respect to the geometry) behaviour of the machine is significantly affected by the cutting conditions. To these belong the loading of the rotating disc by the mass of the work piece, angular velocity of the rotating disc and the operating time of the machine. Based on these observations it can be stated that for prediction of work piece features it is essential to know the behaviour of the machine tool in the whole range of the operating speeds and loading of the rotating disc. A part of the proposed methodology for measuring vertical lathes seems to be very suitable for a design of a diagnostic system that could be applied on large rotating disc. Furthermore, it is recommended to extend the doctoral thesis in order to develop a unit for compensation of geometrical errors on rotating discs of vertical lathes.
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Design and Development of Experimental Device for Testing the TEP Acetabula and Wear Identification using Optical Method
Houfek, Martin ; Kratochvíl, Ctirad (referee) ; Hortel, Milan (referee) ; Hlaváčková, Milada (referee) ; Florian, Zdeněk (advisor)
Today is the implantation of joint replacements, although a radical, but very functional restoration frequent way ill joint. The implants are placed high demands on their biocompatible and long-term function, which is directly related to wear of joint replacements in the human body. Therefore, analysis of the complex behavior of the implant in the human body is a fundamental problem of biomechanics of implants. This issue is dedicated, this dissertation thesis. Dissertation thesis deals with the solution design and development of experimental device for testing the TEP acetabula and wear identification using optical method. The proposed device allows the joint burden hole TEP physiological manner, but by working with the acetabulum burdened by Power resultant joint axis passes through the hole. The physiological loading of articular wells and evaluating the size of the loss of polyethylene is currently intensively addressed. The results of this study may in the near future, serving as information for assessing the conduct of wear prosthetic hip joint in vivo. The work is devoted to solving the problem of the size required to detect the loss of polyethylene for joint replacement arthroplasty: Design and development of experimental equipment for testing the acetabulum of the hip joint arthroplasty. Identify wear using optical methods. Design and development of experimental equipment was made in the system Inventor Professional 2010 at the level of 3D modeling. Great attention was paid to the design fit into the acetabulum TEP testing machines and gripping the acetabulum into an optical device. Management options were tested with combinations of experimental equipment engines. Suggestions were made and then tests for fixing the acetabulum into an optical device. Has the possibility of depth analysis and identification of wear joined with innovative solutions to evaluate the loss of polyethylene acetabulum arthroplasty. Identification of abrasion (loss of polyethylene) joint arthroplasty holes were carried out experimental measurements using an optical holographic interferometry. The comprehensive analysis of the results of experimental measurement of the loss of polyethylene shows that this method can identify both the size but also an area where there is even to small changes in the surface, which depend on the abrasion. One can also say that using this method we are able to affect the will or displacements that affect the size of the loss of polyethylene in joint arthroplasty hole. Despite the number of known and lessons learned arising from the results of solving the problem of design and development of experimental equipment for testing the acetabulum and hip arthroplasty wear identification using optical methods, this work is that the initial study to identify problematics wear of joint replacements. Complete resolution of this issue is beyond the scope of one doctoral thesis.
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Theoretical and Practical Approaches to Private Equity under Conditions of the Czech Republic
Rajchlová, Jaroslava ; Kislingerová, Eva (referee) ; Rejnuš, Oldřich (referee) ; Suchánek, Petr (referee) ; Zinecker, Marek (advisor)
Author of this dissertation focuses on venture capital financing in the Czech Republic. Individual aspects of venture capital financing from the perspective of investors and also businesses are researched and evaluated in this work and formulated proposals for changes that may lead to the development of venture capital financing in the Czech Republic .This research is based on findings published in foreign scientific journals and own research. This dissertation has several scientific objectives. It is necessary to identify the evaluation criteria used by the investors to evaluate the proposed business plans. It is also important to research the nonfinancial added value and to determine the forms of support businesses receive from the investors. The final objective is to identify the limitations of venture capital financing in the Czech Republic. A list of recommendations that should improve the condi-tions of venture capital financing is formulated based on these identified limitations. Primary research was conducted with the help of questionnaires and interviews. Resulting qualitative data was evaluated with the help of Microsoft Excel. Thorough analysis of the qualitative data allowed the formulation of conclusions which can be found in the final part of this work. This dissertation provides a complex view of venture capital financing in the Czech Republic, its specifics, conditions and limitations.
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Identification of probiotic bacteria in complex food matrices and dietary supplements
Cesnak, Filip ; Konečná, Jana (referee) ; Trachtová, Štěpánka (advisor)
Theoretical part of the thesis deals with the general characteristics of probiotic bacteria, their effect on human health and with technological demands imposed on them. Furthermore the thesis deals with actual methods of bacterial identification, especially on the base of polymerase chain reaction. Presence of the declared probiotic bacteria was analysed with the polymerase chain reaction (PCR) and the DNA was isolated from the sample of food additive with the use of magnetic particles.
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Forgotten villa by Karel Hannauer and the sociology of family housing
Hrabová, Martina ; Macek, Petr (advisor) ; Švácha, Rostislav (referee)
The impulse for this work was the archive discovery that enabled identification of an early work of the architect Karel Hannauer. In Prague quarter Libeň the author revealed a functionalist villa, previously known only from an article in a contemporary journal, hidden under a radical reconstruction made in the late thirties. The work covers several thematic issues. It deals with Karel Hannauer's participation in forming the Czechoslovak interwar architecture and his contribution to the transition of foreign influences (especially Le Corbusier's) to the Czech architectural design. The author focuses particularly on the architecture of family houses and in details describes four villas that Hannauer designed during the period of ten years before World War II. She also follows the changes of the political regimes influenced the structure of inhabitants and how the usage patterns and the appearance of the houses were changed during the time. By this way the thesis concerns also the relationship of the architecture and the sociology of housing. Coincidently Hannauer theoretically studied and taught the sociology of the architecture in the forties and fifties, when the totalitarian regimes restricted him from his architectonical work. Besides literature, the work is based on archival documentation studies, a...
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Risk analysis and evaluation of sources of public water supply
Novotná, Aneta ; Bednářová, Bronislava (referee) ; Vymazal, Tomáš (advisor)
The thesis is focused on the identification, quantification and assessment of risks in the supply of drinking water, the application of appropriate methods for specific public water supply, the environment and operation. WaterRisk method based on EN 31010 Risk Management - Techniques of risk assessment methods are chosen - analysis of possible defects and their consequences (FMEA), Pareto diagram and Ishikawa diagram. The aim of the thesis is analyze and assess the quality, environmental and safety risks to the public water supply system and use tools for their management and elimination. The results will be compared and evaluated the advantages and disadvantages of each analysis.
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Propaganda fiction of the Protectorate of Bohemia and Moravia period
Kolezsar, Michal ; Janáček, Pavel (advisor) ; Holý, Jiří (referee)
The thesis deals with Czech activist fiction of anti-Semitic and openly pro-Nazi stance in the Protectorate of Bohemia and Moravia between 1942 and 1945. This type of fiction has yet been widely ignored in the Czech (or Czechoslovak) scientific literature in spite of the fact that it belonged to the so-called "Popular Literature" at that time and therefore could have some (and maybe significant) impact on Czech readership. For that reason one of the main objectives of this paper is to identify and describe particular pieces. The identification and description is based primarily on the original material research of archival documents, newspapers and publications. On the basis of theoretical disputes and reviews in the official Protectorate press it also attempts to define officially demanded fundamental characteristics of the so-called "New Art" (or "The Art of the New Europe"). In another perspective (concerning themes and motives) it aims to distinguish specific categories in the tendentious literature of this period. It is argued that the basic types were: 1) Novels with the strong anti-Semitic accent (emphasis is laid upon a typification of characters); 2) Labour-novels; and 3) "Geopolitical" novels in which the fictional world of the "New Europe" is created.
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Empirické eseje o pravidlech měnové politiky a inflaci
Vašíček, Bořek ; Turnovec, František (advisor) ; Šmídková, Kateřina (referee) ; Macháček, Martin (referee) ; Babecký, Jan (referee)
This dissertation is divided into four essays, each of them having its own structure and methodological framework. Although each of the essays making the chapters of the thesis is self-contained, their topics are very closely related. Consequently, the reader will be able to follow the thesis in its unity. Essay I is a selective survey of the extensive, mostly theoretic, literature dealing with monetary policy rules. We aim at contextualization of the monetary policy rules in the existing monetary economics literature. We explain the logic, the inspiration and the history of the rules for the monetary policy conduct. We distinguish between instrument rules and targeting rules as two basic categories. Finally, we resume specific issues related to policy rules for small open economies. Essay II studies the logic of short-term interest rate setting pursued by 15 EU countries before and after the launch of the EMU. We employ econometric estimation of the augmented Taylor rule (TR) for individual 15 EU countries and the Euro area. Although a vast empirical evidence is available for the major economies like the US, the UK or Germany, there is an important gap in our understanding of the factors behind the short-term interest rate dynamics in smaller economies. We find that in the period preceding the euro adoption, the TR is a poor representation of monetary policy setting in most EU countries and that many central banks considered decisions made by dominant economies rather than their domestic macroeconomic developments. The analysis of monetary policy rule of the ECB features additional problems related to the heterogeneity of the EMU. We argue that results based on Euro-area aggregated series, commonly presented in empirical studies, are subject to diverse econometric problems. We provide some evidence that the ECB is concerned also with national information and propose quasi-panel analysis as a viable framework. Essay III explores the relation between the existing monetary policy and domestic price stability in small open emerging economies, in particular the 12 EU new member states. This work has three principal objectives. First, it aims at revealing the logic of interest rate setting pursued by monetary authority of each country. The linear specification of the Taylor rule, applied already in the Essay II, is accompanied by an extensive analysis of nonlinearities in monetary policy rules and the inference on their possible sources. We find that the official monetary policy is sometimes inconsistent with the empirical evidence on the short term interest rate setting. The second objective consists in revealing the determinants of the inflation process. We have found that inflation rates are driven not only by backward persistency but also by the forward-looking component. Third, we employ analysis of the conditional inflation variance so as to give account on the viability of the existing monetary policy setting for price stability. We conclude that the policy of inflation targeting seems to be preferable to exchange rate peg because it allows decreasing not only inflation rate but also its conditional variance. Essay IV seeks to shed light on inflation dynamics of four CEEC (Czech Republic, Hungary, Poland and Slovakia) and test when the predominant model of inflation, the New Keynesian Philips Curve (NKPC), is consistent with the data of these countries. According to the microfounded NKPC, the current inflation is related to inflation expectations and the real marginal cost. The empirical validity of this model has recently become a subject of major controversy in the monetary economics. Although we find some favorable evidence for the NKPC, it seems to be too restrictive model for small open economies. In particular, the failure of the NKPC to explain the inflation dynamics of these countries may be related to the assumption that inflation is related to forward-looking price setting of domestic monopolist firms while our evidence suggests that prices in CEEC have an important backward-looking component and the inflation is significantly driven by external factors like the exchange rate and the foreign inflation rate.
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