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The activity of biotransformation enzymes in mouflons with dicrocoeliosis and in healthy mouflons
Urbánková, Marie ; Szotáková, Barbora (advisor) ; Gavelová, Martina (referee)
Charles University Faculty of Pharmacy Department of Biochemical Sciences Hradec Králové, Czech Republic Field: Patobiochemistry and xenobiochemistry Candidate: Mgr. Marie Urbánková Consultant: Ing. Barbora Szotáková, Ph.D. Title: The activity of biotransformation enzymes in mouflons with dicrocoeliosis and in healthy mouflons Abstract In vitro activities of cytochromes P450 (7-alkyl/aryloxyresorufin dealkyl(aryl)ases, testosterone hydroxylase/oxidase, 7-methoxy-4-trifluoromethyl-coumarin demethylase), flavine monooxygenases (toward thiobenzamide), reductases of carbonyl group (toward oracin, 4-pyridine-carboxaldehyde, 1-acenaphthenol, DL-glyceraldehyde, ketoprofene, naloxone, daunorubicin, metyrapone) and cojnugation enzymes (p-nitrophenol-UDP- glukuronosyl transferase, UGT, 1-chloro-2,4-dinitrobenzene glutathione-S-transferase, GST) in old, female mouflons (Ovis musimon, Bovidae), both in healthy ones and those suffered from dicrocoeliosis were studied and compared. This parasitary disease is caused by Dicrocoelium dendriticum. Various methods were used, especially spectrophotometry, spectrofluorimetry, and method based on incubation of enzymes with relative specific substrate followed with HPLC analysis of biotransformation products. The amount of proteins was determined using methods with reduction of...
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Zlepšení metod předpovědi termické konvekce pro účely letecké meteorologie
Dvořák, Petr ; Řezáčová, Daniela (advisor) ; Brechler, Josef (referee)
This rigorous thesis is engaging by some processes in boundary layer of the atmosphere, namely rise and running of thermals, focused on vertical motion and speeds of thermals, and on methods of their measurement and forecasting. It exploits data, measured by the GPS receivers and loggers aboard of gliders and paragliders during flying over Czech Republic, and data from aerological soundings, provided by Praha-Libus observatory. Measurement was in progress in so called cross-country flight season 2007 and 2008. The solution of this research is improvement of forecasting of vertical velocity of thermals and can be used in specialised forecasts for private and recreative flying and in forecasts of thermal turbulence.
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Translation and Cross-cultural Validation of the Individual Zones of Optimal Functioning Questionnaire
Prokešová, Eva ; Hátlová, Běla (referee) ; Chalupová, Eva (advisor)
Bibliographical ldentification Author's first name and surname: Eva Prokešová Title of the Master's thesis: Translation and cross-cultural validation of the Individua! Zones ofOptimal Functioning Questionnaire Supervisor: PhDr. Eva Tomešová, PhD Year of the defence: 2008 Abstract: The main aim of the present study was a translation of the Individua! Zones of Optimal Functioning questionnaire (IZOF), and an intercultural validation ofthe Czech version. The IZOF model is a reputable method in the field of sport psychology. This model stresses the importance of both pleasant and unpleasant emotions on an athlete's successful and unsuccessful performance pattems. The main purpose of IZOF is to describe, predict, better understand, and explain the dynamics of the emotion- performance relationship. The Czech version of IZOF was designed in cooperation with sportmen as translators, using results from qualitative research requesting atletes to describe emotions experienced prior to and during their performance (N = 156); existing emotion and affect scales in Czech (especially POMS and CSAI-II) were also analysed. The first Czech version of the IZOF questionnaire was analysed in a pilot study using protocol analysis and the final version was created with the cooperation of experts from the field ofsport psychology....
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Prevention of HIV / AIDS at the grammer school
Pečánková, Tereza ; Holmerová, Iva (advisor) ; Olejník, Radoslav (referee)
This diploma thesis is trying to describe the actual situation of methods concerning the education about HIV/AIDS at the grammar school programs. It is focused rather in finding the teachers' interest to this topic, their cooperation with the experts and with the children. In the theoretical part there are the general information about the HIV/AIDS, characteristic of the illness, way of the transmission, treatment etc. This part also focuses to the description of the prevention activities of the public bodies in the Czech Republic. The practical part introduces the results of the research, which evaluate the present state of the education about the HIV/AIDS in the grammar schools. Subjective answers from the informants in combination with the known facts are forming a good general overview to the actual situation in that domain. The author within the evaluation offers several possibilities which might be a contribution to the future changes conducting to the positive developments of the current situation.
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Allergens of natural origin
Kavková, Kateřina ; Jílek, Petr (referee) ; Tůmová, Lenka (advisor)
Kateřina Kavková The aim of this diploma thesis is to create the summary of plants and natural compounds which can cause contact, inhalant or food allergies. Their incidence is documented by case reports, the most of them came from Europe, Asia and America where are these problems solved and science in these regions pays attention to allergies in general. Asteraceae family is the most often cause of allergy (10,8 %) thanks to sesquiterpene lactones, on the second place there is Lamiaceae family (7,2 %) with the content of fragrances and oils. The next position is engaged by families Anacardiaceae and Fabaceae (6 %). In the comparison with previous studies Asteraceae allergy is on the decline, but the number of subject positive to cosmetics and fragrances is increasing. Less amount of articles discuss about propolis and latex sensitivity. Source of allergies can be found in plants and animals as well. Particular case reports describe allergy and its diagnosis, identification of main allergens, therapy of resulting problems and eventually recommend next arrangements including prevention. The tables with complemented information present new pieces of knowledge incorporated to scientific periodics and journals from 2004 till 2009. The most of cited articles was published in Contact Dermatitis.
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Cabaret "Červená sedma" in the light of archival materials of Czech Radio
Vítková, Eva ; Ottlová, Marta (advisor) ; Douša, Eduard (referee)
This bachelor's thesis maps the situation, in which the archive of the "Červená sedma" cabaret, that is in large part deposited in rooms of the Czech Radio archive, in the present days is found. It compares the dates from the former catalogue, that was managed by the members of the cabaret themselves, with the real today's situation. It even shows individual differences and discrepancies, that were during the revision found. This thesis also concentrates on the "Červená sedma" as a part of the Czech or more precisely the Czechoslovak Radio broadcasting and encourages programmes, in which this company occured, either directly by its members, or indirectly through the actors of other generations or memorial programmes devoted to it.
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Alzheimer's disease in the current health and social policy
Čepeláková, Kristýna ; Dobiášová, Karolína (advisor) ; Angelovská, Olga (referee)
Univerzita Karlova v Praze Fakulta sociálních věd Veřejná a sociální politika Diplomová práce Bc. Kristýna Čepeláková Alzheimerova choroba v současné zdravotní a sociální politice Alzheimer's disease in the current health and social policy Praha 2017 Vedoucí práce: Mgr. Karolína Dobiášová, PhD. Abstract (in English): My dissertation deals with the system of care for patients with Alzheimer's disease in the Czech Republic. For the first objective is to describe this piecemeal issue and confirm, that it's a public- policy problem for the present and will be public-policy problem for the future too. I will collect information about the various measures that the system of care for this type of patients affected. Through content analysis of available resources in the field of care for patients with Alzheimer's disease I will identify the main problem points area of health and social policy. I will place great emphasis on social responsibility for this type of patients and on the impact of public policy measures on the target group of thesis. As a target group I will define not only patients with Alzheimer's disease, but also informal carers, including their close surroundings. They are under great physical and psychological pressure and meets with obstacles in the form of provided formal care services, reduction...
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Analysis of the health insurance system in the Czech Republic after year 1989
Zubrová, Soňa ; Čabanová, Bohumila (advisor) ; Orságová, Petra (referee)
UNIVERZITA KARLOVA V PRAZE FAKULTA SOCIÁLNÍCH VĚD Institut sociologických studií Katedra veřejné a sociální politiky Soňa Zubrová Analysis of the health insurance system in the Czech Republic after year 1989 Abstrakt Praha 2011 Abstrakt The system of the Czech Republic health insurance stands for one of the pillars of the social security in the Czech Republic. Within last twenty years is has been changed significantly several times. The changes have been intended to contribute mainly to the reduction in the number of exploited sickness leaves, to the strengthening of responsibility of employees, employers and physicians. After 1989 the system faced many legal modifications. This thesis is focused on analysis of the health insurance system in the Czech Republic after year 1989. The theoretical resources of the thesis are human and social rights, social security and its principles. The main segment of the theoretical part of the thesis is a function of the right for social security and a description of health insurance. The exploratory part of the thesis analyses the chosen occurrences relating to the health insurance system problems and thereby it responds to questions asked in the introduction of the thesis. The research has proved a diminishing percentage of sickness leaves in connection with accepted...
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The pilgrimage church of the Holy Trinity at Trhové Sviny
Nedbalová, Alice ; Oulíková, Petra (advisor) ; Royt, Jan (referee)
The pilgrimage church of Holy Trinity in Trhové Sviny Abstract This thesis presents a monograph of the pilgrimage church of Holy Trinity near Trhové Sviny. It focuses on its origin, historical background and the benefactors of the building and finally on the artistic value of the church. The work deals not only with a description of the church's architecture, but also looks into patterns and analogies with the Bavarian pilgrimage churches such as the one in Kappel near Waldsassen. Interestingly, the unifying element is the iconography of the Holy Trinity, which is reflected in the architecture and decoration of the church, in frescoes and the mobiliar. This iconographic concept is cleverly thought out, especially in the Trinitarian symbolism of the number three and the triangle motif that is repeated several times here. A valuable contribution is the main altar from Matěj Václav Jäckel, who probably created the church pulpit as well. The frescoes celebrating the Holy Trinity were made by Carlo Bonanelli who worked in the nearby České Budějovice. The church is an interesting result of the unifying principles of Baroque theology with the ultimate art design work. And we must not forget the question of the baroque feeling demonstrated through an impressive setting of the church in the landscape. Pilgrimage...
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Key competencies for sustainable action in early education curriculum
Vošahlíková, Tereza ; Teodoridis, Vasilis (advisor) ; Činčera, Jan (referee) ; Dostál, Petr (referee)
Univerzita Karlova v Praze Pedagogická fakulta ABSTRACT KEY COMPETENCIES FOR SUSTAINABLE ACTION IN EARLY EDUCATION CURRICULUM PhDr. Tereza Vošahlíková Vedoucí práce Doc. RNDr. Vasilis Teodoridis, Ph.D. Katedra biologie a environmentálních studií Pedf UK Doktorský studijní program pedagogika Externí konzultantka Prof. dr. Ute Stoltenberg Institut für integrative Studien, Leuphana Universität Lüneburg Praha 2012 The thesis introduces environmentally oriented concepts in early education curriculum with one leading point of view: key competences for sustainable action. Key competences represent new, open ended form of educational goals. Early education curriculum defined broadly as all educational content (planned, realized and hidden) presents a field of study of this thesis. In this field, a new concept, education for sustainable development, should be implemented worldwide. The question is, how far and how successfully can this concept be introduced in the early education curriculum on the level of educational goals. There are many general strategies and models of curriculum revision. In order to structure the empirical study, a hierarchical model of macro-, meso- and micro level of curriculum was established. This model allows examination of two ways of education for sustainable development implementation,...
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