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Multipurpose Town House on Křížová Street, Brno
Souček, Michal ; Kynčl, Jakub (referee) ; Ruller, Ivan (advisor)
The aim of this Diploma Thesis was the design of multipurpose town house located on Křížová Street, Brno with the significant housing part, but also with areas for administration offices and commercial use. The project focuses on new attempt and concept of inner part of the block, as well as on connection into the existing historical urban structure. A new multi-storey monolithic house with seven floors and glass façade was designed. Commercial area is located in the parterre of the house, second floor is used for offices and the roof (7th floor) gives attractive place for a café. The rest of the house (3rd to 6th floor) has a dwelling purpose. Diploma Thesis copes with the function of yard and underground parking place, as well.
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Information systems in medicine with a focus on scientific information in clinical practice and biomedical research
Papíková, Vendula ; Vlasák, Rudolf (advisor) ; Souček, Martin (referee) ; Špála, Milan (referee)
The dissertation deals with information systems in medicine with a focus on scientific information. Topics are treated from the perspective of a user, whether a scientist or a doctor in the clinical practice. Attention is therefore devoted to information sources, search tools, the ability to communicate and share scientific information, and current methods of analytical and synthetic processing of published medical literature, both at the level of value-added information services and at the level of automatic text processing. -- The topics mentioned above are divided into separate chapters. A large portion of the text devoted to new information sources is added to an overview of traditional biomedical databases. Further, current trends in biomedical information searching are described. Next, current possibilities of communication and sharing of scientific knowledge via the Internet and applications and services of Web 2.0 ar listed. Particular attention is paid to scientific information for clinical desicion-making support. -- The dissertation newly presents a comprehensive classification of biomedical information resources supplemented by illustrative examples. Further, five case tasks are described. Three of them demonstrate the claims made in the text. The other two test non-traditional retrieval...
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Determining the amount of insurance coverage for a structure damaged by a tornado
Souček, Martin ; Klika, Pavel (referee) ; Čech, Josef (advisor)
The diploma thesis deals with the issue of determining the amount of insurance compensation for a damaged object of a family house in the village of Hrušky in the Břeclav region. This work is divided into a theoretical and a practical part. In the theoretical part, terms related to insurance and real estate valuation are defined. The practical part is dedicated to the actual solution of the problem, where the object is valued in a cost way in three time periods. At the end of work, the itemized budget determines the cost of repairing the damaged object to its original condition and assesses the adequacy of the amount of the final insurance payment.
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Invaluable Library Services
Řehák, Tomáš ; Souček, Martin (advisor) ; Ivánek, Jiří (referee) ; Šušol, Jaroslav (referee)
The paper deals with the issue of valuation and calculation of efficiency of public library services. In the introduction the paper explains the motivation for the research undertaken. The first (theoretical) chapter places the whole issue in the general economic and legislative framework, in particular relating libraries to the concept of public goods and describing different approaches to determining their value. It explains the concepts of efficiency and return on investment (ROI). It describes specific approaches to measuring the efficiency of libraries as a whole, with particular attention to the contingent valuation method and its development. It describes in detail several studies that the author considers to be of particular methodological value. The chapter concludes with information and descriptions of two key ISO standards that are directly related to the issue. Chapter 2 describes research on the efficiency of the library as a whole (referred to as ROI 1.0) conducted in 2012 at the Municipal Library in Prague (MKP) and verified in three other cities. Chapter 3 captures the effort to determine the effectiveness of one selected service (ROI 2.0), namely lending services (i.e. circulations of library items). It describes the chosen taxonomy of individual library services and the basic...
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Material Culture and Everyday Life in Residences of Ottavio II Piccolomini
SOUČEK, Martin
The work presented here uses modern theoretical principles, which have been applied in recent years in the research of material culture and residential networks of aristocratic estates. Heuristically, it is based on a set of previously unused sources, which are deposited mainly in the State Regional Archive Zámrsk, Piccolomini Family Archive, Náchod, 1431-1881. The work is based on the analysis of the preserved castle inventory from 1732, the palace inventory from 1739, financial documents from the 1830s and reports of the Piccolominis´ agent Adalbert Anthony Gayer. The author is interested not only in the material equipment of the residences of Ottavio II. Piccolomini (1698-1757) in Náchod, Ratibořice and Prague, but he also asks questions about the daily running of the residences. He also focuses on the people who occupied these buildings.
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Selected aspects of methotrexate treatment in patients with rheumatoid arthritis
Hloch, Karel ; Pávek, Petr (advisor) ; Souček, Miroslav (referee) ; Tomčík, Michal (referee)
Charles University, Faculty of Pharmacy in Hradec Králové Training Workplace Department of Social and Clinical Pharmacy Doctoral Degree Program Clinical and Social Pharmacy Candidate MSc. Karel Hloch Supervisor prof. PharmD. Petr Pávek, Ph.D. Advisor assoc. prof. MUDr. Tomáš Soukup, Ph.D.; PharmD. Martin Doseděl, Ph.D. Title of Doctoral Thesis: Selected aspects of methotrexate treatment in patients with rheumatoid arthritis Introduction and objectives Rheumatoid arthritis (RA) is an autoimmune disease typically connected with chronic inflammation of the joints, causing their swelling and pain. The prevalence of RA is about 1% in the general population. A crucial role in higher morbidity and mortality in RA patients has been associated with increased inflammatory activity. Methotrexate (MTX), a drug with immunosuppressive activity, is the most frequent drug of choice used in RA therapy. It seems that main anti-inflammatory effect is mediated via release of purine nucleoside adenosine. The status of patients with inflammatory diseases is influenced by activation of A2a and A3 adenosine receptors. High caffeine (adenosine receptor antagonist) consumption may therefore lead to alteration of MTX treatment efficacy. 1) The aim of first study was to determine whether RA patients who had discontinued...
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Development of investment opportunities for individual investor in the Czech Republic since 1990
Souček, Martin ; Mejstřík, Michal (advisor) ; Teplý, Petr (referee)
Purpose of this thesis is to describe historical development of the Czech capital market and collective investment market, to be able to analyse further investment opportunities of individual investor within these markets from the year 1990. In the first part of thesis we are describing institutional development of financial market from transition period through privatization until presence. In the second part we set up limiting conditions and theoretical presumptions for our analysis of investment opportunities of individual investor. We define also separate investment strategies and predictive models. In the third part of thesis we compare profitability of separate investment strategies in combination with various predictive models. Purpose of this analysis is to find out within our observed period optimal investment strategy based on historical data and econometric methods and verify usefulness of various investment rules.
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Web news aggregation: current world trends
Tatranská, Martina ; Papík, Richard (advisor) ; Souček, Martin (referee)
Diplomová práce se zabývá agregací zpráv neboli monitoringem médií od jejího vzniku až po současnost. Cílem práce je uvedení do problematiky agregace zpráv a analýza nejvýznamnějších systémů zabývajících se elektronickým monitoringem médií. V první části práce jsou vymezeny pojmy týkající se této oblasti a následně nastínění problematiky kvantitativního nárůstů informací, který se odráží i pii tvorbě zpravodajských informací, jejichž základní vlastnosti jsou v práci popsány. Druhá část práce více definuje činnost agregace zpráv, její historický vývoj vycházející z výstřižkových služeb, jak ve světě tak i v českých podmínkách, typologii a způsoby užití. Nejsou opomenuty fonnáty pro poskytování obsahu, jejich stručná historie a význam v agregaci zpráv, největší důraz je zde kladen na RSS kanály. Další část práce je věnována analýze vybraných významných systémů. V závěru jsou popsány trendy vývoje agregace zpráv a jejich možné perspektivy.
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Making of successful websites in commercial sphere
Mráz, Martin ; Souček, Martin (advisor) ; Šlerka, Josef (referee)
Tato bakalářská práce je věnována návrhu webu z hlediska grafiky, použitelnosti, přístupnosti a obsahu. První kapitola se věnuje návrhu webu a informacím, které je nutno znát ještě před samotným začátkem procesu. Druhá kapitola poté shrnuje grafickou stránku webu, rozebírá kompozici a doporučení. Třetí kapitola je věnována použitelnosti a faktorům, které ji ovlivňují. Zmíněna je i problematika použitelnosti nových technologií. Kapitola o přístupnosti rozebírá pravidla přístupnosti a upozorňuje na nejčastější problémy přístupnosti u komerčních webů. V poslední kapitole jsou rozebrány komponenty, které ovlivňují úspěšnost textu a rady, jak takový text napsat.
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