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Bipolar Disorder and Diabetes Mellitus
Růžičková, Martina ; Höschl, Cyril (advisor) ; Haluzík, Martin (referee) ; Papežová, Hana (referee)
Despite lots of research, the genetic and pathophysiological basis of bipolar disorder (BD) remains unclear. One of the possible reasons is that BD spectrum comprises a heterogeneous group of different subtypes of the illness sharing certain pathophysiological or genetic mechanisms. Patients with co-morbid diabetes mellitus (DM) may represent such a subgroup of BD with a distinct pathophysiology and possibly different clinical characteristics of BD. This thesis is aimed at investigating the possible link between BD and DM. Bipolar patients have about 3 times higher risk of DM (type 2 in particular). The first part of my thesis outlines the possible links between DM and BD, including medication, alterations in the hypothalamo-pituitary axis and signal transduction, and genetics. In the second part, I examined the possible differences in clinical characteristics between patients with (N=26) and without (N=196) co-morbid DM. Next, I examined the variables showing differences between groups, using logistic regression. Patients were recruited via The Maritime Bipolar Registry. The prevalence of DM was 11.7%. Diabetic patients were significantly older than non-diabetic patients (P < 0.001), had higher rates of rapid cycling (P = 0.02), more chronic course of BD (P = 0.006), more disability (P < 0.001), lower...
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The role of the Czech woman in the family from the public
KLOUDOVÁ, Hana
The contemporary role of Czech women in the families is being discussed a lot. Czech families have significantly changed and so the role of women. A traditional patriarchal model of Czech families has been disrupted.This Bachelor thesis is mapping public opinion on the role of Czech women in the families and the difference between traditional and present models. The theoretical part deals with historical development of women roles, a current structure of Czech families, new forms and ways of spouse coexistence, birth rate decline, two-career wedlocks, family roles of men and women and their housework share. A quantitative method, a questionnaire, was used for the research survey. The questionnaire consisted of 24 closed questions and 4 closed questions supplemented with factual data. Some colleagues, friends and family members from the South Bohemian region were the respondents. All of them were over 18. From two hundred questionnaires distributed, 148 were completed and used so the return rate was 74 %. Hypothesis 1 assumed a traditional family role of the Czech woman and was confirmed. Hypothesis 2 assuming high absence of ?a new woman? in a Czech family was not confirmed. Although the findings show a prevalance of the traditional family model, the percentage of traditional views has declined compared to the previous sociological research surveys. A man has lost his traditional breadwinner role while a woman, except for her housework and child care, is fully employed, earns quite big money, attends courses of further professional development and represents her husband. The findings of this Bachelor work can serve students of social and health care studies and form a basis for further research work in this field.
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The Use of Artificial Intelligence on Financial Markets
Hortai, František ; Budík, Jan (referee) ; Dostál, Petr (advisor)
This thesis deals with the design of a model for trading on financial markets by using artificial intelligence. The work describes some methods of artificial intelligence, description of financial market and stock market trading. The result of this work is a model of an expert system which uses fuzzy logic for investing and a functional model for predicting the course of shares trends using artificial neural networks. Both models algorithms were designed and tested in MATLAB.
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Merger of a parent company and its subsidiary and its specifics compared to the general regulation of mergers
Trnka, Filip ; Čech, Petr (advisor) ; Štenglová, Ivanka (referee)
Merger of a parent company and its subsidiary and its specificity compared to the general regulation of mergers The topic of this diploma thesis are the mergers between parent companies and subsidiaries. In my view, this is a very relevant topic nowadays which can be often faced in practice. The aim of this thesis is above all to describe the differences between this type of mergers and the other types (it is not my aim to describe the whole process of mergers between parent companies and subisdiaries step by step as a large part of regulation of this process is similar to the general merger process regulation). This thesis is divided into eight main chapters. In the first chapter current regulation and its historical development are outlined. The aim of the second chapter is to compare the incentives which lead to mergers between parent companies and subsidiaries and the incentives which lead to the other mergers. Of course, both partly overlap. However, there exist some differences, which are described in this chapter. Chapter three deals with the mergers between parent and subsidiary joint stock companies. To a large extent it consists of the analysis of the simplified approval process of such merger, which is included in the Czech legislature. Furthermore it includes the analysis of the share...
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The nursing process in a patient with complications following a lung transplantation
Goldbrichová, Věra ; Nikodemová, Hana (advisor) ; Kučková, Eva (referee)
You are holding the bachelor thesis which concludes my studies in the 2nd Medical School of Charles University. This thesis is meant for the public arena for those with some knowledge regarding medicine. For the topic of my thesis I have chosen the medical care process for a patient with complications after a lung transplant. The objective of this project is to present to the reader questions and answers regarding lung transplants, with emphasis on the seriousness of such an operation giving detail to some of the problems which may arise and the care required. These are issues which a nurse may, and most likely will, be faced with in her profession. The thesis is structured into two basic parts. The first, the theoretical section, is about the anatomy of the respiratory system and lung transplants. With the main detail describing the care required after a transplant and frequently experienced complications. In the second, practical section, the actual case of a patient with complications after a lung transplant is discussed in detail. The basic personal history was written up on the first day of care, this is followed by a description of treatment throughout the course of hospitalization and the planned nursing care. In conclusion, the thesis will discuss the final care of the patient and what the project...
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Civil-Military Culture in re-united Germany
Kučera, Tomáš ; Střítecký, Vít (advisor) ; Karásek, Tomáš (referee)
In the course of last two decades the German foreign policy has significantly changed as far as the use of military force is concerned. It can be seen that this process is a result of a rational adaptation to new circumstances. In this thesis an effect of social norms and shared beliefs on shaping the German military policy is accented. The concept of civil-military culture was used in order to explain why the German military policy still differs from a "normal rational policy". This German exceptionality can be on the one hand explained by persisting influence of the culture of restraint in using military power that is still a noticeable part of the German strategic identity, on the other hand this thesis pointed out an effect of shared perceptions of German society about the military. Results of an analysis of how mass media report on Bundeswehr and its soldiers are used as evidence that the dominant image of Bundeswehr as a humanitarian organisation strongly limits the way of how soldiers can be deployed. Whereas post-conflict reconstruction and humanitarian missions are seen to belong to basic tasks for Bundeswehr, according to the persistent image of the military any kind of a battle deployment is believed to be inappropriate and inadequate.
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Study of dispersity of nanoemulsive drug carriers
Hájková, Hana ; Doležal, Pavel (advisor) ; Vachek, Josef (referee)
SUMMERY Theoretical part of this work is focused on explanation of such terms like nanoparticules and nanoemulsions and their usage within peroral and topical administration. Next part explains the merit of zeta potential and DLVO theory, which influence the stability of the elements. Off course, also the principle of the measuring of viscosity is mentioned, because viscosity is taken into consideration in case of measuring of the element dispersion. The experimental part is focused on determination of the partije size by photon correlation spectroscopy by temperature of 25řC and 37řC. The measurement was taken in chronological succession to estimate the stability of dispersion system. It was also measured electrokinetic parameter - zeta potential, which plays a fundamental role by keeping the stability of nanoemulsions. It was proved, that the size of the elements gets settled after approx. 1 week, further changes are not so striking anymore, not even by the increase of temperature to 37řC. Since creating the emulsion (approx. 1 week), the major share of the size of particles (about 60-95%) was ranging between 120-175 nm. As well zeta potencial remains in stable range (+2 mV - -0,6 mV) by the increase of temperature to 37řC and adding of three pH highs of buffers. From the gained results we can draw...
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Estimating the impact of the 2012 liquor prohibition on crime
Krejsa, Jiří ; Dušek, Libor (advisor) ; van Koten, Silvester (referee)
This thesis focuses on capturing causal link between alcohol consumption and one of its externalities, crime. The quasi-natural experiment of the Czech temporary ban on hard liquor following an outbreak of methanol poisonings in September 2012 provides a valuable setting for evaluation of the alcohol-crime relationship. Over the course of the prohibition, violent crime rates fell by approximately 10 %, just like the aggregate of aggravated assault, criminal threatening, vandalism and property damage. In addition, the biggest share of reduction in crime falls on weekend criminality. The number of offenders under the influence of alcohol dropped by approximately 18 % for traffic-related offences and by 28 % in non-traffic offenses. The possibility of the reduction in crime being caused by lower detection capabilities of the law enforcement was examined. The reduction in reported cases of e.g. driving under the influence might be to a large extend explained by lower detection, but it could have reduced only rates of victimless crimes. Finally, the property crime rate was not significantly affected by the intervention, except for burglaries into bars and restaurants.
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Implementation of Personal Scheduler
Filák, Jakub ; Květoňová, Šárka (referee) ; Lukáš, Roman (advisor)
The goal of this bachelor´s thesis is to explore the possibilities of the time scheduling and to create a tool for its simplification. Besides managing personal tasks and events, the tool can also be used for planning appointments with other users, mainly due to a user diaries sharing and a searching tool for appropriate dates. The first part of the thesis deals with the technologies employed, followed with a part concerning the requirements for the time scheduling tool and a description of an implementation of the tool. In the last part the programme capabilities are evaluated, along with the results of the work.
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Elizabeth Bishop: Translation as Poetics
Machová, Mariana ; Quinn, Justin (advisor) ; Hilský, Martin (referee) ; Costello, Bonnie (referee)
The dissertation thesis is based on the concept of translation as an aesthetic stance not limited to translating from one language to another, but informing a certain type of original creation. In order to speak about this aesthetic stance which shares some of its features, methods and values with those often found in the work of a translator the term "translation poetics" is proposed. The American poet Elizabeth Bishop (1911-1979) is presented and examined as a representative of this poetic type. A study of her lifetime work as a translator creates a context and background for the formulation of the basic characteristics of Bishop's "translation poetics", and, consequently, for the reading of her poems. The detailed chronological examination of all her translations (from Ancient Greek, French, Portuguese and Spanish) is followed by an outline of the main poetic principles which lie both behind translation and the original creation, and these are exemplified by detailed close-readings of a selection of Bishop's poems. The key features of Bishop's "translation poetics" (the interest meetings and borders; tensions between domination and submission, and between the insider and the outsider position; sensitivity towards the plurality of voices and of perspectives; a stress on dialogue and interaction;...
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