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Proteins demaged by oxidative stress, their role in physiology and ageing of yest cells
Mikešová, Jana ; Palková, Zdena (advisor) ; Borčin, Kateřina (referee)
Reactive oxygen species (ROS) are regularly produced in cells as a by-product of aerobic metabolism. Hence, organisms developed various defence mechanisms, which are able to avoid molecular damages caused by ROS under physiological conditions. In stress conditions, however, such defence mechanisms are not sufficient to avoid molecular damages. Accumulation of oxidized proteins is supposed to be a reason for ageing and many diseases including Friedreich's ataxia, Amylotrophic lateral sclerosis, Alzheimer's disease and many others. During oxidative stress, reactive oxygen species are reflected in oxidation of cystein residues in transcription factors, regulation proteins and active canters centers of enzymes. Oxidative modifications however could lead also to changes in transcription factor activity and activation of specific pathways, including changes in gene expression, cell cycle and proteolysis. This work shows defence mechanisms, ROS and proteins altered by reactive oxygen species that may function as important signalling molecules, which are essential for many cellular processes.
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Seniors and active aging in the seniors'house in Ostrava
Lipowská, Jana ; Tuček, Milan (advisor) ; Trusinová, Romana (referee)
Demographic aging of population brings a number of needs, demands and changes in many areas of social life. In this case, Czech Republic has accepted several documents which also contain National Programme of Preparation for Aging for 2003 - 2007, and then for 2008 - 2012. This document regards to the concept of active aging and old age, which was accepted by the World Health Organization in the 90's, defined as a process of health quality development, seniors' social participation and the entire rising of a quality of life in an old age. The activity becomes desirable and proper way of the seniors' life. The diploma project is focused on the seniors' activities, specifically on the offer of activation activities and their usage in Ostrava seniors' house. The theoretical part is pursued on the definition of aging and old age, physical, mental and social changes and the science disciplines, which are focused on those. Besides, it deals with social services, closer with the seniors' houses, activity and activation in the houses and about the concept of active aging, National Programme of Preparation for Aging and European Year of Active Aging. The empirical part is focused on the case study of seniors' house in Ostrava, based on semi-structured and Focus group with seniors and activation workers. It...
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Development of Prague's Housing Estates: Ageing and Functional Use
Worschová, Markéta ; Ouředníček, Martin (advisor) ; Machala, Branislav (referee)
There lives currently one third of population in the post-socialist housing estates in the Czech Republic. Because of many problems that accompany the estates, many scientific studies deal with the topic. In my study, I focus on analysis of the age structure changes in Prague housing estates and investigate whether it corresponds to the level of the functional use. The analytical part is divided into two sections. The first one is the analysis of the age structure based on the statistical data. The second section is an assessment of the level of the use in Prague housing estates through a questionnaire survey in a selected estate. In principle, it was confirmed that the Prague housing estates really have been aging and this trend affects to some extent functional use of the locality. It is important to solve the needs of estates individually so that the changes were effective. Based on the analysis the conclusion is that the Prague housing estates have good prospects for the future. Key words: Prague; housing estates; ageing; functional use
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History, present and perspectives of the Universtities of the Third Age in the Czech republic
Kuželová, Monika ; Šerák, Michal (advisor) ; Beneš, Milan (referee)
The bachelor thesis is focused on senior's education that is put into wider psychosocial and economic framework. My thesis characterizes ageing, old age and seniors. Ageing of population is evidenced by demographic dates. It describes negative social phenomenons, especially "ageismus" and an endeavour of society to restrict these negative social phenomenons e.g. prosenior education. The thesis mentions economic impacts of ageing upon society. It contents some documents, both national and international, for endorsment of seniors. These documents declare social, medical and economic importance of care of senior's group. These documents place emphasis on active old age that ensure better quality of life in old age. The education is one of the possibilities. The senior's education is attached enormous meaning. There is originated new pedagogic discipline, which deal with specifics of senior's education, gerontopedagogy. Senior's education is part of lifelong learning and it has mostly special-interest character. The highest degree of education offers the Universities of the Third Age. These universities are extended all over the world. The universities offer so many programs that help to seniors to orientate in contemporary changeable world, these programs meet the needs of new pieces of knowledge and...
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The efficiency of memory and physical training of the elderly
Waidingerová, Iveta ; Štětovská, Iva (advisor) ; Šípek, Jiří (referee)
The thesis discusses the training of cognitive functions and physical exercise in the elderly population. It concerns the issue of active ageing, which is a very topical one. The theoretical part describes the findings and results of the latest studies mainly in seniors of good cognitive health. The practical part presents the research in how the seniors of good cognitive health respond to the combination of cognitive training, in other words memory training, and physical exercise. Keywords: ageing, active ageing, cognitive function training, memory training, physical exercise
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The Social-activating Programs for Seniors in Klub Remedium
Jančová, Jaroslava ; Vodáčková, Daniela (advisor) ; Kodymová, Pavla (referee)
This study deals with social-activating programs for seniors. It tries to answer the question how seniors evaluate social-activating programs in Klub REMEDIUM. The main task is then to find reviews of the social services provided at Klub REMEDIUM its visitors and draw cocnclusions along with a concept of posible improvement of service delivery. As a target then I'm also interested in the contribution that seniors are seeing from the use of these services. To achieve the goals I have used a quantitative method of data collection survey, which I also completed by the qualitative method of personal interviews and my own observation for deeper understanding of the topic. I have found that seniors evaluate these programs strongly positive. But I also encountered the problem areas that have become an incentive to improve service delivery.
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Specifics of third age education
Zachová, Adéla ; Kopecký, Martin (advisor) ; Mužík, Jaroslav (referee)
The purpose of this diploma work is to describe the possibilities of senior education and specific needs of senior education. The population of Czech republic is ageing. In order to this it is necessary to define very important terms like age, ageing, age management. Demographic situation will need new solutions in learning, because people will have to work longer than it was in history. To be successful at labour market, older people will have to pass various courses and trainings. It is also necessary to prepare for age, because people are living longer, this period can last 30 or 40 years. Learning is a very good way to keep healthy and vital. Senior education has many variations - for ambitious people it can be University of third age, for less demanding students it can be for example Leisure time university. It was proofed, that senior education has positive influence on their health, they are not so often sick, have better mood. Seniors can thank to learning understand the current world and that is useful for them and for the society too. Key words: age, ageing, age management, senior, lifelong learning, specifics of senior education, ageing society, preparing for ageing
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Residents of retirements homes in region of Zlín in point of demographic view
Lukácsová, Hana ; Šídlo, Luděk (advisor) ; Hulíková Tesárková, Klára (referee)
Residents of retirements homes in region of Zlín in point of demographic view Abstract Presented work introduces the law no. 108/2006 on social services that determines retirements homes as one of the facilities providing social services. The capacity of these facilities in the Zlín region is evaluated with the help of availability indices and facility normatives. More detailed attention was drawn to an analysis of age, gender, former permanent address and dependence degree of residents in selected retirement homes. This part of the research is based on data provided by five retirement homes in Zlín region. Obtained data was evaluated with the Kaplan-Meier method in order to estimate surviving function for these clients. The resemblance was tested employing the determination of the null hypothesis by log-rank test or Wilcoxon test. Keywords: ageing, residents of retirements homes, law on social services, survival analysis
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