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Use of Markov decision processes for modelling of collective games
Zákutný, Roman ; Antoch, Jaromír (advisor) ; Koubková, Alena (referee)
In this thesis, a model based on the continuous-time Markov process is built and implemented and later applied on an one chosen collective game. An extensive analysis of available data is carried out to build a regression model to estimate parameters of the game model. An usableness of the game model is shown by a simulation process. Pros and cons are evaluated in a comparison analysis against the application of the discrete-time Markov chains, how it was described in my bachelor thesis [Roman Zákutný (2007)]. In conclusion are discussed possible extensions for other collective games.
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Jewish New York. Diversity of Jewish immigration waves 1820-1924
Zubková, Katarína ; Šedinová, Jiřina (advisor) ; Ebelová, Ivana (referee)
Jewish New York today is indisputably the center of the Jewish Diaspora. It is the largest and the richest Jewish community outside of Israel. Already since the beginning of the 201 h century it has had the largest urban Jewish population in the world. Nevertheless, Jewish New York is not only vast, but immensely complex as well. Jews were arriving in various historical immigration waves from different places in the world, each one of them preparing the ground for the next wave. The goal of my M.A. thesis called "Jewish New York. Diversity of the Jewish Immigration Waves 1820- 1924", was to identify the waves of Jewish immigrants that were transforming the city of New York and to describe the way they settled in, adapted and lived in New York. The time span is limited to the century of the mass migration starting in 1820 and ending in 1924 after the immigration restriction legislation was adopted. I was inspired by reading Jewish American authors such as I. B. Singer, Bernard Malamud, Philip Roth or J.S. Foer, particularly in specialized seminar conducted by Hana Ulmanova, PhD., at the Department of English and American Studies. The final decision to write about this topic was influenced by the fact that in 2007 I received a one semester scholarship at the Department of Hebrew and Judaic studies at New York...
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Determination of the kinetics of crushing industrially produced tablets
Čechalová, Kateřina ; Řehula, Milan (advisor) ; Musilová, Marie (referee)
7.2.Summary Determination of the Kinetics of Crushing of Mass-Produced Tablets The degree paper aimed to determine the optimal parameters of the devices for the evaluation of the strength of tablets. Rates of preloading from 0.01 to 0.1 mm/s, preloading from 1 to 4 N, and rates of the cycle from 5 to 20 N/s were tested. These parameters were evaluated on the basis of the records of the force-course. Deformation curves were employed to calculate the course of crushing in mm, crushing force in N, and energy of crushing in N.mm. The reading of the curves was evaluated as well. The obtained results were evaluated using the method of the analysis of diameters following Otto. The results show that for the standard determination of mechanic resistance of tablets, the following adjustment of the device is suitable: rate of the cycle, 0.01 N/s, preloading, 4 N, rate of preloading, 5.mm/s.
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Protein-protein interaction mapping of cytochrome P-450 by methods using chemical modification and mass spectrometry
Ječmen, Tomáš ; Černá, Věra (referee) ; Šulc, Miroslav (advisor)
Cytochromes P-450 (P450s) belong to haemoprotein superfamily and they are responsible for metabolism of a wide variety of compounds, among others many drugs and carcinogens. P450s serve as the terminal oxidases in the mixed function oxidase system in cooperation with a redox partner NADPH: cytochrome P450 reductase (CPR) providing input of two electrons to the reaction cycle of P450. The CPR can be substituted by other redox partner of P450, cytochrome b5 (cyt b5), to deliver the second electron. Three dimensional structure of P450 is required in order to fully understand its reaction mechanism. At the present time, a homology model of cytochrome P-450 2B4 (CYP 2B4) is available in our laboratory. In this study, the mapping of interaction domain between CYP 2B4 and cyt b5 employing a crosslinking agent EDC to form amide bonds between close complementary charged amino acid side chains was the first goal. We have identified five interacting amino acid pairs in total using mass spectrometry (MS). The second research interest was to verify and refine the CYP 2B4 model using a photoaffinity labelling with N-(p-azidobenzyl)-N-methyl-p-aminophenylamine probe. This photoreactive probe is known as CYP 2B4 ligand binding to the central iron atom of haem. After photoactivation the arginine 197 was found by MS...
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ICT investment decisions
Náprstek, Miloslav ; Chocholatý, Drahomír (advisor) ; Balcar, Filip (referee)
The goal of this dissertation is to create instruction, how to proceed at creation of initial analyses in pre-investment phase of informatics investment. There are described for this reason various types of used studies during this phase of service life of this investment in the dissertation. There is created tool in the dissertation, which enables to make feasibility study for organizations, so that it was suitable for informatics investment for concrete environment. Designed procedure is verified by means of the study of practicability of the concrete investment project and its evaluation. Implementation the project proceeding tool designed for concrete bank institution is tested investment intention.
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The *.eu domain and the protection of third persons' rights
Blažek, Jiří ; Dobřichovský, Tomáš (advisor) ; Císařová, Zuzana (referee)
Rozvoj internetu, jako fenoménu konce 20. století, sebou přináší mnohé otazníky a výzvy, jak technické, tak právní, na které je mnohdy třeba odpovídat a řešit je bezprostředně poté, kdy vyvstanou. Postupem času toto "kybernetické" prostředí přestalo být ryze vědeckou záležitostí a začalo se, čím dál více, komercionalizovat. Právě spolu se zvyšujícím se využíváním internetu jako virtuálního tržiště, se začaly objevovat problémy, na které bylo potřeba adekvátně reagovat. S velikým zjednodušením lze pojmenovat dva stěžejní okruhy problémů, se kterými se "provozovatelé" internetu v současnosti především potýkají, a těmi jsou zabezpečení dostatečného počtu "internetových adres" a vypořádání se s neduhy, které registraci těchto "adres" provázejí. Těmito jsou především spekulativní registrace doménových jmen, když tyto zcela oprávněně vyvolávají reakce subjektů, které se takovou registrací cítí poškozeny. Životní cyklus doménových jmen, tedy proces počínající jejich registrací a případně končící zrušením takové registrace, popř. diskvalifikace doménového jména z možnosti jeho další registrace, je upraven zejména tzv. soft law - tedy pravidly vydávanými jednotlivými správci TLD. K hlavním znakům této oblasti lidské činnosti patří až minimalistická úprava zákony jednotlivých států (tedy řečí oboru teorie práva,...
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The principle of primacy of European law and the legal order of the Czech Republic
Ondřejková, Jana ; Kysela, Jan (advisor) ; Tryzna, Jan (referee)
105 Summary - shrnutí v anglickém jazyce; klíčová slova The presented thesis challenges the simple reading of the principle of primacy of European law as a "rule of primacy in application". Both the analysis of the early decisions of the Court of Justice of the European Communities (ECJ) on the primacy of Community law (Van Gend en Loos, Costa, Internationale Handelsgesellschaft, Simmenthal) and the short insight to the political and legal development of the European integration indicate, that the differences among scholars in theorising about the meaning and the scope of application of the principle of primacy are significantly based on their pre-understanding of the relationship between the European and national legal system. Therefore, the scope of application of this principle is assessed according to the subsequent decisions of the ECJ. The special regard was given to the possible exceptions based on EC/EU Treaties and/or recognized by the ECJ. The most common readings of the principle of primacy - the rule of interpretation, the collision rule, the derogation rule, the legal principle and the essential quality of European law - were studied in order to establish which of them correlates the best with the results of the decisions of the ECJ on the scope of application and exceptions to this principle....
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Maternity in later age or phenomenon of the present time
Zadražilová, Jana ; Miskolczi, Martina (advisor) ; Antovová, Michaela (referee)
The bachelor´s work concerns with maternity in late age and lays the goal to draft present trends showing in the Czech Republic, using qualitative research to reveal the opinions and experience of women facing the mentioned problem and find out how much they are influenced in decision about the time of birth of the child by the partner. The work brings basic historical overview of changes in family behaviour, theoretical approaches that try to explain these changes and moreover it devotes also to occurence of evolutional defects at children of older mothers, also older fathers and rising interest about methods of assisted reproduction in connection with still rising age of mothers. Using the analysis of the trends of fertility from the year 1989 was found that it got to decrease of total fertility and specific rate of fertility is still moving to higher age of women but with lower intensity. The average age of women is still rising and with this also the number of performed cycles of assisted reproduction. In the same time also the occurence of inborn defects at the age of women 35 and more is relatively high. Thanks to qualitative research were in most of cases confirmed the arguments for postponement of maternity got from the professional literature. Moreover was found low level of knowledge about the occurence of inborn defects at children of older expectant mothers and relying on the methods of assisted reproduction in case of inability to become pregnant. The attitude of the partner in deciding about the time to have the first baby is either the same as the woman partner or the attitude of the woman is in this matter primary. In question of having a baby or not is deciding the attitude of the partner.
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Czech baroque coronations
Hrbek, Jiří ; Maur, Eduard (advisor) ; Hojda, Zdeněk (referee)
The Bohemian coronations in the baroque period certainly ranked among the most significant politi cal events in the entire Habsburg monarchy in the 17th and 18th centuries. In my study, I tried to compare the coronations of Ferdinand III. (1627), of his two sons Ferdinand IV. (1646) and Leopold I. (1656) and of Leopolďs son Charles Vl. (1723). I discussed four spheres, in which we can see these events. The first one was the political sphere: after the battle on the White Mountain, Bohemia became a hereditary monarchy, so it was never more necessary for Habsburgs to deal with the Bohemian estates, when the son of the King should be coronated. But the vote of the new king was only one limitation of the King's power, another limitations, which originated from the early modem political philosophy, continued further in the baroque period. There was no responsibility to the estates, but King was responsible to the God and to this effect he took an oath during the coronation mass before the unction. When the archbishop of Prague as a consecrator was pouring the holy oil with balsam ( chrisma) on the head of the King, he received the Goď s Grace like the jewish kings of the Old Testament (David, Salomon). The coronation connected the politics with the religion and only after the unction the King could receive the...
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