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Isolation of active compounds from algae and their application in cosmetic products
Nováková, Laura ; Byrtusová, Dana (referee) ; Skoumalová, Petra (advisor)
The bachelor thesis is dedicated to the study of active substances and antioxidant effects of cultivated microalgae. We compared the results with a commercial alga that is freely available. In the theoretical part we focused on description of algal metabolites in cosmetics and a brief description of the methods used in their testing. In the experimental part there were analyzed three types of extracts (aqueous, alcohol and oil) from 4 species of algae. It is mainly the content of polyphenols, flavonoids and antioxidant activity that is determined. According to the results, the highest content of active substances was found in oil extracts. All extracts were encapsulated into liposomes. The average size of the nanoparticles was in range of 200 nm to 300 nm. The particles were stable enough also for long-term stability. The largest decrease was observed in the oil extract of the cultivated algae Chlorella vulgaris. The cytotoxicity of oil extracts was realized by MTT test on human cell cultures HaCaT. Finally, we concluded that the prepared liposomal particles could be used for anti-aging cosmetics.
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EVALUATION OF THE IMPACT OF A PROCESS INNOVATION ON SALES IN COMPANY BEDNAR FMT S.R.O.
Bartošek, Jakub ; Nováková, Lucie (referee) ; Bočková, Nina (advisor)
This bachelor thesis focuses on the evaluation of the impact of process innovation in the field of sales at company Bednar FMT s.r.o. in 2014–2018. The theoretical part defines specific terms related to process innovation as well as terms and indicators of financial analysis. The analytical part describes the monitored company from the point of view of basic data, it also provides information about process innovation and financial analysis is carried out on the basis of theoretical background.
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Strategy of Business Development
Nováková, Libuše ; Veselý, Josef (referee) ; Koráb, Vojtěch (advisor)
This thesis is aimed at business plan of further development of the company XY, s.r.o. The theoretical basis for the work include basic concepts related to the focusing on the main idea of the company´s development plan. The analysis section deals with the evaluation of the current problém and includes the identification of key factors in the wider context of the environment, the summary of which is then followed by a suitable strategy for the implementation of future development. In this part, analyzes of External and internal factors are used. The proposals are based on a performer SWOT analysis. This section lists appropriate measures to eliminate risks in the field.
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Favorit Brno / cycling stadium - bicross track / architectural study - design / stage 2021/22
Nováková, Lucie ; Žalmanová, Petra (referee) ; Šindlar, Jiljí (advisor)
The assignment of the diploma thesis is an architectural study of a cycling stadium - velodrome in the Pisárky district in Brno for TJ Favorit Brno. The existing velodrome is located southwest on the edge of the Brno Exhibition Center on Křížovského Street. The Velodrome no longer meets the current requirements of track cycling, but it is historically valuable and has its genius loci. The new 250 m long wooden bike track (together with other parameters of the International Cycling Union) and its associated sports grounds are "inserted" into the existing velodrome, which is modified and reconstructed according to requirements. The grandstands have been preserved. The built-in building with a new track is then completely roofed, creating an enclosed space. As part of the stadium reconstruction, a new facility was also created for TJ Favorit Brno from a modular container system; These are changing rooms for athletes, administrative areas, and facilities for visiting clubs and athletes and IP areas. The container construction system for sports facilities is very practical, economical, fast, environmentally friendly, variable, and flexible to the current requirements of a constantly evolving sport. The Anteroom and ground floor in the southern part of the existing velodrome is equipped with services for the public: a cafe, souvenir shop, cash register, information center, service, and a bicycle and sports equipment store. The new track with grandstands is covered with ETFE foil anchored to new lattice trusses, which are connected to the existing roof.
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The Use of Methods of the Project Management for Real Company
Nováková, Lucie ; Ing.Jana Hývnarová (referee) ; Smolíková, Lenka (advisor)
The diploma thesis is focused on the packaging industry. Through the application of project management methods it proposed a solution a sewing workshop for the VMT Ecopack s.r.o. The Introductory part is aimed at the description of basic concepts and all subsequent stages of the project, focusing especially on the methodologies in the planning part. The Analytical section primarily states information about the company including conducted analysis of the internal and external area. The last part has been designed and developed my own proposal to establish, encompass and develop a new section of the company through the use of effective project management tools and approaches.
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New possibilities in wound healing
Nováková, Laura ; Szotkowski, Martin (referee) ; Skoumalová, Petra (advisor)
The diploma thesis is focused on the study of fibrous wound dressings prepared by electrospinning method from natural biopolymers. Three active ingredients were added to the dressings: ampicillin, ibuprofen and collagenase, which are responsible for relieving pain, reducing the risk of infection and selectively removing necrotic tissue in the wound. The theoretical part describes the therapeutic dressings currently available on the market and the most common methods of nanofiber production. The experimental part evaluates the optimization of the preparation of gelatin, alginate and chitosan fibrous wound dressings, which were subsequently enriched with active substances and their gradual release into the model environment was determined spectrophotometrically. Antimicrobial effects against E.coli and S. epidermidis strains andantifungal activity against C. glabrata yeast were monitored. Finally, two cytotoxicity tests on the human keratinocyte cell line HaCaT confirmed the safety of the prepared products, which can serve as bioactive skin dressings in the future.
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