National Repository of Grey Literature 235 records found  1 - 10nextend  jump to record: Search took 0.01 seconds. 
Development of UHPLC-MS/MS method for separation of Amaryllidaceae alkaloids
Burianová, Kristýna ; Nováková, Lucie (advisor) ; Chocholoušová Havlíková, Lucie (referee)
Charles University in Prague, Faculty of Pharmacy in Hradec Králové Department of analytical chemistry Candidate: Kristýna Burianová Supervisor: prof. PharmDr. Lucie Nováková, Ph.D. Consultant: PharmDr. Veronika Pilařová, Ph.D. Title of Doctoral Thesis: Development of UHPLC-MS/MS method for separation of Amaryllidaceae alkaloids In this master thesis, a method for the separation of 30 alkaloids of the Amaryllidaceae family was developed using ultra-high performance liquid chromatography coupled with tandem mass detection (UHPLC-MS/MS). Chromatographic conditions and mass spectrometer parameters were optimized. In the first step of optimization, screening of 10 analytical columns was performed on an ultra-high performance liquid chromatography coupled with photodiode array detection (UHPLC-PDA). Those tested columns were Acquity UPLC BEH C18, Acquity UPLC CSH C18, Acquity UPLC BEH Phenyl, Acquity UPLC CSH Phenyl-hexyl, Arion Plus C18, Acquity UPLC BEH Shield RP18, Ascentis Express RP-Amide, ACE Excel C18-PFP, Kinetex PFP, and Kinetex F5. Acquity UPLC BEH Phenyl, Acquity UPLC CSH Phenyl-hexyl, and Acquity UPLC CSH C18 as they provided the highest separation score for the analyzed isomeric groups of analytes were selected for further optimization. The optimization of MS conditions was performed by...
Method development for UHPSFC-PDA-MS analysis of ginsenosides in dietary supplements
Vaľková, Tatiana ; Nováková, Lucie (advisor) ; Pilařová, Veronika (referee)
Department: Department of analytical chemistry Candidate: Tatiana Vaľková Supervisor: Prof. PharmDr. Lucie Nováková Ph.D. Title of the diploma thesis: Method development for UHPSFC-PDA-MS analysis of ginsenosides in dietary supplements The aim of this diploma thesis was to develop an analytical method for the analysis of ginsenosides, the main active compounds of Panax ginseng, in dietary supplements. Measurements were carried out with ultra-high performance supercritical fluid chromatography (UHPSFC) system Acquity UPC2 coupled with photodiode array (PDA) and mass spectrometry (MS) detection. The first step was the column screening using 11 stationary phases in combination with a CO2-based mobile phase and 4 organic modifiers: MeOH, MeOH/ACN (1:1), MeOH + 10 mM NH3, MeOH + 2 % H2O. The method optimalization was carried out on 4 stationary phases with the best selectivity and peak resolution during the screening. This optimalization involved changes in the composition of the mobile phase, gradient elution settings, back pressure regulator pressure, and column temperature. Finally, the effect of make-up solvents was evaluated. The final UHPSFC-PDA-MS method used Torus 2-PIC column, gradient elution and CO2 + MeOH/ACN (2:1) + 5 % H2O mobile phase. The make-up solvent used was MeOH + 10 mM NH3. The...
EVALUATION OF THE IMPACT OF A PROCESS INNOVATION ON SALES IN COMPANY BEDNAR FMT S.R.O.
Bartošek, Jakub ; Nováková, Lucie (referee) ; Bočková, Nina (advisor)
This bachelor thesis focuses on the evaluation of the impact of process innovation in the field of sales at company Bednar FMT s.r.o. in 2014–2018. The theoretical part defines specific terms related to process innovation as well as terms and indicators of financial analysis. The analytical part describes the monitored company from the point of view of basic data, it also provides information about process innovation and financial analysis is carried out on the basis of theoretical background.
Favorit Brno / cycling stadium - bicross track / architectural study - design / stage 2021/22
Nováková, Lucie ; Žalmanová, Petra (referee) ; Šindlar, Jiljí (advisor)
The assignment of the diploma thesis is an architectural study of a cycling stadium - velodrome in the Pisárky district in Brno for TJ Favorit Brno. The existing velodrome is located southwest on the edge of the Brno Exhibition Center on Křížovského Street. The Velodrome no longer meets the current requirements of track cycling, but it is historically valuable and has its genius loci. The new 250 m long wooden bike track (together with other parameters of the International Cycling Union) and its associated sports grounds are "inserted" into the existing velodrome, which is modified and reconstructed according to requirements. The grandstands have been preserved. The built-in building with a new track is then completely roofed, creating an enclosed space. As part of the stadium reconstruction, a new facility was also created for TJ Favorit Brno from a modular container system; These are changing rooms for athletes, administrative areas, and facilities for visiting clubs and athletes and IP areas. The container construction system for sports facilities is very practical, economical, fast, environmentally friendly, variable, and flexible to the current requirements of a constantly evolving sport. The Anteroom and ground floor in the southern part of the existing velodrome is equipped with services for the public: a cafe, souvenir shop, cash register, information center, service, and a bicycle and sports equipment store. The new track with grandstands is covered with ETFE foil anchored to new lattice trusses, which are connected to the existing roof.
The Use of Methods of the Project Management for Real Company
Nováková, Lucie ; Ing.Jana Hývnarová (referee) ; Smolíková, Lenka (advisor)
The diploma thesis is focused on the packaging industry. Through the application of project management methods it proposed a solution a sewing workshop for the VMT Ecopack s.r.o. The Introductory part is aimed at the description of basic concepts and all subsequent stages of the project, focusing especially on the methodologies in the planning part. The Analytical section primarily states information about the company including conducted analysis of the internal and external area. The last part has been designed and developed my own proposal to establish, encompass and develop a new section of the company through the use of effective project management tools and approaches.
Usage of information technologies for optimalization of payment transactions
Kost, Tomáš ; Nováková, Lucie (referee) ; Kříž, Jiří (advisor)
This master's thesis analyses the problems concerning system of payments especially clearing credit transfers, bank statement of accounts and interconnection with the company’s information system. It proposes suitable ways of optimalization which in the upshot lead to a better exploitation of information technologies and simplification for the human operator.
Evaluation of the Financial Situation in the Firm and Proposals to its Improvement
Nováková, Lucie ; Měsíčková, Bohumila (referee) ; Strnadová, Michala (advisor)
The Bachelor's thesis focuses on evaluation of the financial situation of a company Jednota, spotřební družstvo v Hodoníně during the years 2010 - 2015. The evaluation of the financial situation of a company is based on materials provided by the company (balance sheet, profit and loss statement and cash flow statement). This thesis also includes a proposal and recommendation for maintaining or improvement financial situation of a cooperative.
Costs reduction in production of Al-alloy castings
Nováková, Lucie ; Lána, Ivo (referee) ; Roučka, Jaromír (advisor)
This thesis deals with solving the most serious internal defects in castings made of aluminum alloys which are cast in sand molds in Slévárna a modelárna Nové Ransko Ltd. The problem solving contains a description of the problematic castings with the investigation of the structure and phases and subsequent detailed analysis of their production. The Author of this thesis also examines the influence of Fe and Mn on a possible formation of the internal porosity with the help of test meltings with the evaluation of the internal structural change. The Author’s design solution is a close checking of chemical composition with regard to the ratio Mn / Fe present in the alloy, the purchase of Foundry Degassing Unit to reduce gassiness of melted metals and better control of gassiness with the help of the appropriate equipment for the density Dichte index.
Description of lathe machines
Nováková, Lucie ; Matějka, Petr (referee) ; Blecha, Petr (advisor)
The bachelor’s thesis deals with description and classification of vertical lathe machines. The text is divided into several coherent chapters. The introduction is concerned with history and basis of the turning. Next part describes basic types of vertical lathe machines and the greatest attention is given to the analyse of particular parts of the machine. The end of the bachelor´s thesis includes some representatives of Czech and foreign producers of the lathe machines followed by the comparison of their products.
The Apartment block Masarykova ctvrt
Nováková, Lucie ; Ležatka,, Lukáš (referee) ; Pavlovský, Tomáš (advisor) ; Petříček, Tomáš (advisor)
By submitting the bachelor thesis is the design of the new building Viladom in Masaryk District in Brno, District of Stránice. The specified plot lies between the Roubalova Street and the Helceletova Street. The building was designed with respect to the surrounding area. The object respects the street line. The underground floor is designed for the parking and storage areas, it has separate cellars to individual apartments. The first floor is dedicated to common areas and a separate flat, the second floor consists of two separate apartments.The third above ground floor contains the largest independent apartment and fourth floor is redistributed among the individual apartments. The floor is dedicated to terraces and living quarters. The main entrance to the building is direct and barrier-free from the Roubalova Street. Entrance for cars is accessible from the Helceletova Street.

National Repository of Grey Literature : 235 records found   1 - 10nextend  jump to record:
See also: similar author names
3 NOVÁKOVÁ, Lada
38 NOVÁKOVÁ, Lenka
90 NOVÁKOVÁ, Lucie
10 NOVÁKOVÁ, Ludmila
3 Nováková, Lada
4 Nováková, Laura
38 Nováková, Lenka
2 Nováková, Leona
3 Nováková, Libuše
1 Nováková, Lidmila
8 Nováková, Linda
10 Nováková, Ludmila
1 Nováková, Luďka
4 Nováková, Ľubica
Interested in being notified about new results for this query?
Subscribe to the RSS feed.