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Controversial issues of self-defence in Czech case law
Houzar, Petr ; Vokoun, Rudolf (advisor) ; Bohuslav, Lukáš (referee)
The focus of the thesis is set on the controversial issues connected with a legal institute of Czech criminal law called "self-defence", and how these controversial issues were dealt with within judicial practice. The first chapter serves as an introduction to the whole topic. The second chapter describes the concept of self-defence, as well as its prerequisites. The self- defence was classed into the system of criminal law. The goal of the third chapter is to define preconditions which are necessary in connection with application of the self-defence institute. The main parts of this chapter describe firstly attacking, first of all and secondly defence. Subsections of this chapter analyse the term of attacking itself, the attacker and his characteristics, the term of harmfulness of such attacks towards society. As for the second part of the third chapter it focuses on the defence itself, its proportionality etc. The fourth chapter is about the role of judicial practice within the context of Czech legal system. This chapter serves as a relevant contribution to the main part of the thesis, which is chapter five. Chapter five introduces specific cases, especially those which were at some point controversial. The specific case is briefly described and the controversial issue is named and further...
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Sanctions for Breaching the Obligations within Employment Law Relationships
Odvárková, Kateřina ; Morávek, Jakub (advisor) ; Štefko, Martin (referee)
The author conceives the presented thesis partly as a case study, when she illustrates different aspects of sanctions on a practical example defined for the purposes of this work. Furthermore, she maps different kinds of aspects related to analyzed sanctions. The thesis is divided into the introduction, five main chapters and the conclusion. Overall, the work has two parts, the first one is the introduction and the first chapter, second part consists of the definition of the practical example, from which it derives, then the second, the third, the fourth and the fifth chapter and the conclusion. In a brief introduction, the author has a think about the meaning of general terms such an obligation, a legal obligation and sanctions for breaching duties. The first chapter contains a definition of terms that are analyzed further in the work. Furthermore, the chapter continues with the general definition of sanctions, particularly from the perspective of legal theory, including the attempt on the author's own definition of sanctions. As an introduction to another part of the work is defined a model case from which the work (partially processed as a case study) further unfolds. The basis of this case is a breach of the obligation to pay out employees wages. On this basis, in the text are more fully...
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The Mechanism of Pathogenesis of Experimental Autoimmune Uveitis and Possilbilities of Their Regulation
Klímová, Aneta ; Heissigerová, Jarmila (advisor) ; Pitrová, Šárka (referee) ; Holáň, Vladimír (referee)
Introduction:Uveitis in an ocular inflammation affecting mostly people of working age. Uveitis is responsible for severe visual impairment despite of expanding new therapeutics. The animal models of uveitis were established, because the wide clinical variability of uveitis limits the studies in human medicine. The goal our project was to establish a reproducible model of experimental autoimmune uveitis in Czech Republic, and further on this model to observe the frequency of CD3+ and F4/80+ cells in retina, to assess the influence of microbial environment on intensity of intraocular inflammation and to test the therapeutical possibilities. Material and methods: The C57BL/6J mice were immunized by retinal antigen (IRBP 1-20, interphotoreceptor retinoid binding protein), enhanced by complete Freund's adjuvant and pertussis toxin and mild posterior autoimmune uveitis was induced. The mice were bred in conventional and germ-free (gnotobiotic) conditions. The uveitis intensity was evaluated in vivo biomicroscopically and post mortem histologically on hematoxylin eosin stained sections according to the standard protocol. The histological eye specimen were analyzed also by imunohistochemisty and by flow cytometry. Each experiment was performed for 35 days. The conventional mice with uveitis were treated...
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Laboratory diagnostics of micrometastases in breast cancer patients
Mikulová, Veronika ; Zima, Tomáš (advisor) ; Svoboda, Marek (referee) ; Průša, Richard (referee)
Introduction: The presence of circulating tumor cells (CTC) in the peripheral blood has been associated with worse prognosis and early relapse in breast cancer patients. CTC determination in the peripheral blood has been considered as a liquid biopsy. The aim of this project was to analyze the presence of CTC followed by their molecular characterization with the potential use not only as a new biomarker for real-time monitoring of therapy efficacy but also as a suitable tool for patient's stratification and individualization of treatment for breast cancer. Methods: A total of 54 patients with diagnosed early breast cancer were enrolled into a prospective study. Ten millilitres of peripheral blood were sequentially collected to test for the presence and characterization of CTC during the follow-up of patients. CTC isolation and detection was performed by AdnaTest BreastCancer™ (AdnaGen AG, Germany), which is based on the detection of EpCAM, HER2 and MUC1 specific transcripts in enriched CTC- lysates. cDNA from isolated CTC has been further used for newly optimized qPCR assays for breast tumor and therapy resistance associated genes: TOP1, TOP2A, CSTD, ST6GAL, KRT19 and reference gene actin. qPCR results have been analyzed by Genex software (MultiD Analysis). Results: 195 blood samples have been...
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From machine to icon:car in popculture from the 60s
Rybář, Václav ; Bednařík, Petr (advisor) ; Jirák, Jan (referee)
An automobile is one of the most important phenomenons of modern technology. Since its origins, it has profoundly shaped our physical, economic, politic, social, cultural and media habitat. The objective of this Master thesis is to analyze the evolution of the role of the car in the popculture from the 60s onwards and its dimensions, with a primary focus on Anglosaxon culture, with excursions to Asia and continental Europe, primarily Czechoslovakia/Czech Republic. The core foundation of the thesis lies in the analysis of the popcultural genres, selected films, TV series, computer games and comic books. The main purpose of the thesis is to reflect upon the identity and conceptual shifts of car, going from a mere transport machine through a vehicle of product placement towards the concept of the icon, a narrative hero of popculture. The hypothesis to verify is that the car has become an essential part of the popculture itself, reflected in many various dimensions: car as a toy, car as a friend, car as a status symbol, car as a narrative extension of the hero and finally, car as a hero and subject. The thesis is divided into five separate chapters, all including case studies. Following an introduction summarizing cultural, economic and historic factors of the car industry, the first chapter describes...
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Usage of Markov chains in banking
Klímová, Hana ; Marada, Tomáš (advisor) ; Prášková, Zuzana (referee)
The aim of the thesis is to get acquainted with the theory of Markov chains and to show how it is used in banking for estimation of credit rating transitions. In the first part, an introduction to the theory of discrete-time and continuous-time Markov chain with discrete state space is provided. In the next part three estimating methods that are used to calculate credit rating transitions - namely cohort method, durability method and Aalen-Johansen estimator are described theoreticaly. In the last part these methods are applied to calculate the matrices of transition probabilities on the basis of real rating migrations. Next an empirical transition matrix is used to simulate set of rating progressions, which are then used for estimating the original matrix by all the above mentioned methods. Finally the distance between the original and estimated matrices is evaluated to show the differences between the methods.
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Questa inFact Capabilities Demonstration Set
Fodor, Dušan ; Krčma, Martin (referee) ; Zachariášová, Marcela (advisor)
This bachelor thesis deals with presentation of working with platform Questa inFact from Mentor Graphics company. In introduction, teoretical information about verication itself is provided and several verication methods are introduced. Teoretical part is followed by examples of usage Questa inFact tool for coverage driven verication and contains set of demonstational samples.
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Environmental impact assessment (EIA) in european law
Králová, Tereza ; Grmelová, Nicole (advisor) ; Zicha, Jiří (referee)
The main goal of this diploma thesis, called Environmental impact assessment (EIA) in european law, is to explain the procedure of environmental impact assessment. Emphasis of this diploma thesis is placed on legislation dealing with the environmental impact assessment and its development. The diploma thesis is divided into five chapters, further it contains the introduction, the conclusion, the list of abbreviation, the list of pictures, attachement and the list of literature. Chapter one defines the environmental impact assessment itself and distinguishes the project (EIA) and strategic (SEA) assessment. Chapter two describes the international law concerning the environmental impact assessment. The most important part of this diploma thesis is chapter three, which contains the analysis of european and czech legislation regarding to the environmental impact assessment. The czech legislation is then compared to legislation of other member states of the EU. Chapter four characterizes the procedure of environmental impact assessment within the Natura 2000. Chapter five analyses the case Temelín with respect to environmental impact assessment.
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Inertial Navigation Unit
Dvořák, Jan ; Hubík,, Vladimír (referee) ; Šebesta, Jiří (advisor)
This thesis is focused on the design and realisation of inertial navigation unit INS. The unit is capable to measure, store and send data to a PC in real-time for a later offline processing. The first part of the thesis introduces the reader with the basic principles of accelerometers, gyroscopes and MEMS sensors. An introduction to coordinate systems and measuring errors is also included. The second and third part of the thesis deals with the analysis of the solution and the implementation of the INS unit. The fourth part of the document is dedicated to the software for the INS unit. This thesis concludes with explanation how the gathered data are processed.
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Nodální regiony v Evropě vymezené na základě letecké dopravy
ROZKOŠNÝ, Filip
This master´s thesis deals with the delineating of nodal regions via civil aviation data in the territory of central European states. This kind of transport has become a very popular type of spatial mobility after its deregulation and liberalization particularly thanks to its speed, cheaper fares and relative safety. Thanks to this spatial mobility of inhabitants, it is possible to delineate borders of regions according to real movements. Supposing usage of aviation data to delineate nodal regions, the airports represent their nodes. The purpose of this master´s thesis was delineating nodal regions via civil transport data in an interesting territory of Central Europe. Its western and eastern part has undergone different historical and political development which has had consequences on the aviation development level. Research input data included number of flights between central European airports for the period of 1 day. The master´s thesis is structured into 5 chapters. The first parts are: introduction and goals, theoretical part and methodology. The analytical part evaluates the whole nodal-region-delineating process and also nodal regions final hierarchical structure. Each partial part of research was depicted into a map and was also expressed by population and area. There are answers on the input hypothesis in the final part of this paper.
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