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Study of mechanical properties and dynamics of biomembranes and single molecules with the use of laser beam - an overview
Jonáš, Alexandr ; Zemánek, Pavel
A micron-sized dielectric particle confined in a laser trap can be employed as a probe for the measurement of forces in the range from piconewtons to hundreds of piconewtons. Thus, if a biological system of interest (e.g. DNA molecule, single myosin or kinesin molecule, cell membrane) is attached to such a probe, its mechanical and dynamical properties (elasticity, viscosty, forces associated with movement) can be studied during its interaction with the environment with unprecedented resolution. This article introduces the basic principles of the laser trapping and force measurement and illustrates on several examples the great potential of the light-based force transducer for exploiting non-invasively the dynamics of basic biological systems.
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Možnosti využití sociálních sítí pro podporu podnikání v autoservisech
Mischaniuk, Mykhailo ; Molnár, Zdeněk (advisor) ; Gála, Libor (referee)
The diploma thesis deals with the problem of using social networks in the field of car repair services. The primary aim is to provide the recommendations for businesses in a structured way on how to better utilize these networks to get better competitiveness. This work is divided into three parts. The first theoretical part deals with basic description of networks and their statistics. This part also covers some basic tools that we can use to analyze and maintain social network platforms. The second analytical part deals with competitive analysis in car repair services and gives an overview of the most popular Runet social network platforms. The third practical part provides structured view on all important aspects of social platform maintenance and behaviour. In this section, you can find the description of various views and the recommendations I give to the specific car repair service.
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Effective dashboard design in the analytical tasks of IS
Janeczková, Agata ; Šedivá, Zuzana (advisor) ; Pour, Jan (referee)
The thesis deals with analysing and designing an effective dashboard. By way of introduction the topics of Business Intelligence, data storages and data quality are described. Then, an overview of analytical outputs is given and the process of their formation is outlined. The basic principles of an effective design of management reports are described, with emphasis laid on the end user. The thesis focuses on important factors of efficiency, such as applicability of transferred information and the form of their transfer. The practical part concentrates on the improvement of the efficiency of a particular dashboard. Besides the rules of a correct design, knowledge of cognitive psychology is also used for this purpose. Upon an analysis of deficiencies of an existing dashboard, proposed changes are incorporated. Changes resulting in more effective transfer of information via a dashboard are based on a theoretical basis of the previous section.
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Clustering and regression analysis of micro panel data
Sobíšek, Lukáš ; Pecáková, Iva (advisor) ; Komárek, Arnošt (referee) ; Brabec, Marek (referee)
The main purpose of panel studies is to analyze changes in values of studied variables over time. In micro panel research, a large number of elements are periodically observed within the relatively short time period of just a few years. Moreover, the number of repeated measurements is small. This dissertation deals with contemporary approaches to the regression and the clustering analysis of micro panel data. One of the approaches to the micro panel analysis is to use multivariate statistical models originally designed for crosssectional data and modify them in order to take into account the within-subject correlation. The thesis summarizes available tools for the regression analysis of micro panel data. The known and currently used linear mixed effects models for a normally distributed dependent variable are recapitulated. Besides that, new approaches for analysis of a response variable with other than normal distribution are presented. These approaches include the generalized marginal linear model, the generalized linear mixed effects model and the Bayesian modelling approach. In addition to describing the aforementioned models, the paper also includes a brief overview of their implementation in the R software. The difficulty with the regression models adjusted for micro panel data is the ambiguity of their parameters estimation. This thesis proposes a way to improve the estimations through the cluster analysis. For this reason, the thesis also contains a description of methods of the cluster analysis of micro panel data. Because supply of the methods is limited, the main goal of this paper is to devise its own two-step approach for clustering micro panel data. In the first step, the panel data are transformed into a static form using a set of proposed characteristics of dynamics. These characteristics represent different features of time course of the observed variables. In the second step, the elements are clustered by conventional spatial clustering techniques (agglomerative clustering and the C-means partitioning). The clustering is based on a dissimilarity matrix of the values of clustering variables calculated in the first step. Another goal of this paper is to find out whether the suggested procedure leads to an improvement in quality of the regression models for this type of data. By means of a simulation study, the procedure drafted herein is compared to the procedure applied in the kml package of the R software, as well as to the clustering characteristics proposed by Urso (2004). The simulation study demonstrated better results of the proposed combination of clustering variables as compared to the other combinations currently used. A corresponding script written in the R-language represents another benefit of this paper. It is available on the attached CD and it can be used for analyses of readers own micro panel data.
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Global Economy Outlook - October 2016
Česká národní banka
The October issue of Global Economic Outlook presents the regular monthly overview of recent and expected developments in selected territories, focusing on key economic variables: inflation, GDP growth, leading indicators, interest rates, exchange rates and commodity prices. In this issue, we focus in detail on the industrial producer price index (PPI), which, alongside the consumer price index (CPI), is a key indicator of inflation on the production side of the economy. We also explain the specifics of the PPI, especially in the EU, and present a model simulation indicating the sensitivity of the PPI to a change in oil prices.
Fulltext:  PDF; PDF
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Design of Experiment for Non-Stationary Processes of Production
Jadrná, Monika ; Macák, Tomáš (advisor)
The doctoral thesis is concerned with the services sector and the area of mass production. Particularly, the optimization of the product portfolio of the travel agency and the optimization of production rounds of ammunition.
The theoretical part deals with the current overview of discussed topic. Further, the terminology and methods of the decision-making process are defined to support decision making. The theoretical basis of research focused on the choice of appropriate input variables in the area of services, and on the choice of a particular material option in the production area and appropriate equipment for the production. The theoretical part forms the basis for the practical part of the thesis.
For the doctoral thesis was chosen an enterprise operating in the defined sector. Product portfolio for the services sector is optimised using Fuzzy logic and Fuzzy sets so that the enterprise can maintain its competitiveness in todays highly ambitious market. Product portfolio for manufacture is optimised for achieving desired properties of the product.
The main aim of the thesis is to propose a new methodological approach for the management of selected business processes in their nonstationary time course. The aim of the practical implementation is to verify the functionality of the proposed methodological approach, both in the area of services and in the field of mass production.
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Design and implementation of e-learning in the area of interest
Marešová, Nikola ; Husa, Jiří (advisor) ; Marek, Marek (referee)
The bachelor's thesis entitled "Design and implementation of e-learning in the area of interest" deals with buying used cars. The essential part of this work is a creation of e-learning course for buyers and other people interested in this area which aims to improve their knowledge. The participants will get an overview of the most common situations and problems they can meet when buying a used car. The theoretical part presents an overview of the topics of the issue of purchase of used cars. It may serve as a theoretical guidance to the e-course, it brings its content. The topics are based on the analysis of information from printed and electronic sources, supplemented by experiences of the author and experts in the field. The practical part deals with the creation of an e-learning course. It contains an analysis of the needs of buyers, the reasons for the creation of the course and the requirements of it, its objectives, a description of the used authoring tool eXe and graphic creation process from the creation of the course after its publication in steps. All this is complemented by the feedback from six volunteers who have expressed an interest in testing the course and then doing a review. Before the creation of the course it was necessary to analyze the situation and find out why such a course is needed. The acquired knowledge was then processed in the course by the synthesis method. For the evaluation method it was used a short personal interview where the author examined satisfaction with the course, its possible shortcomings and suggestions for improvements or enhancements.
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Subsidy Support of the Sustainable Waste Management
BEDNÁŘOVÁ, Renata
The subject of the dissertation is the issue of the waste management with special emphasis on the recycling of the construction and demolition waste. The recourse is an analysis of the key instruments regulating the activities and behaviour of market operators in this field toward fulfilling all-society priorities and principles of the sustainable development, where special accent is put on the area of subsidy policies and programmes. The aim of the dissertation is to analyse and evaluate the setting of the selected subsidy programme in terms of economic and ecological efficiency with the emphasis on the assessment of the impact on the recipient. The subject of the research will be a priority axis 4 "Improvement of Waste Management and Removal of Old Environmental Burdens" within the Operational Programme Environment 2007 - 2013. In the literature review basic concepts and important definitions are defined, followed by the comprehensive and complex searches of the problematics from different angles of view. First of all, the global aspect of environmental protection is discussed, broader historical, legal, economic and political contexts, that are essential fundament for understanding the current and future challenges both globally regionally, are summarized. Hereafter, a more detailed description of the situation of the European Union is followed, then the overview is completed by a detailed view at the state of the problematics in the Czech Republic. Subsequent chapters are devoted to a detailed analysis of the waste management sector, again in terms of global, European and national standpoint, in the end the view is focused on the key issue of the dissertation problematics of construction and demolition waste. In the application part the fulfilling of the stated objective of the dissertation through four defined hypothesis is solved. Hypotheses verify the efficiency and appropriateness of the setting of the system of subsidies in the frame of the monitored programme. The emphasis is imposed on the assessment of the impact of the allocated subsidies to the private entities on their economic and environmental efficiency.
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Energy assessment of building
Žůrek, Petr ; Horák, Petr (referee) ; Hirš, Jiří (advisor)
Diplomová práce se zabývá energetickým sektorem v Ruské Federaci se zaměřením na sektor budov a jejich energetickou efektivnost. Je zde vytvořen základní přehled předpi-sů a norem týkajících se sektoru budov a dotační programy vytvořené Ruskou vládou na snížení energetické náročnosti. V praktické části je provedeno energetické hodnocení dané budovy v podmínkách Čr a Ruské Federace. Výpočty energetických bilancí budovy jsou prováděny pro klimatické podmínky daných zemí a v souladu s národními předpisy. Na základě energetických bilancí jsou navrženy opatření na úsporu energie. V závěru je provedeno ekonomické posouzení, s ohledem na rozdílné ceny energií a nákladů na provedení návrhových opat-ření v České republice a Ruské Federaci.
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Role and competences of the nurse in compared with Czech Republic and Namibia
KLYNCYPAROVÁ, Hana
Theoretical grounds The nursing profession among the professions and mission. Job nurse is one of very important professions. Nurse is an independent worker who has an irreplaceable role in the provision of care. In practice, certain roles, such as the role of a caregiver, the educationalist, communicator, the role of the lawyer, consultant, person, who brings the change, manager and researcher. These roles are constantly interacting and are interconnected. Health care has multidisciplinary and multiprofessional character. Although each of these professions contribute to care in a unique way, all share certain skills that are necessary to ensure the quality of care. Over the years there have been increasing professional skills and increase competencies. Expanded the range of services for which they previously did not have the competence or sisters had a written authorization of a doctor. This work is made up of theoretical and empirical part. The theoretical part provides an overview and information on the field of nursing and its history, dealing with the care system and education system in the Czech Republic and Namibia. The following list of findings roles and their importance in the nursing profession. The last part deals with the competencies of nurses in both countries. The aim of the thesis: The aim of the study was to determine the roles and responsibilities of nurses in the Czech Republic and Namibia. To to obtain this information were chosen research question what role nurses advocate in the Czech Republic and Namibia, and what are nurses in the Czech Republic and Namibia competence. Methods: To ensure the necessary data and information was chosen qualitative research through deep interviews. Nurses who were interviewed were from a hospital in the Czech Republic and nurses from hospitals in Namibia Keetmanshoop. All interviews were recorded on a Dictaphone andwritten down on the paper. Results: Recorded interviews were analyzed after writing down, we were using paper and pencil methods. Dialogs were openly coded. The analysis of these data arose following categories: the role of caregivers, the role of the teacher, communicator, the lawyer's role, the role of counselor, role of person who brings the change, the role of leader, manager's role, the role of researcher and categories of competence. Individual categories were assigned to subcategories. All informationwere are illustrated by clear diagrams of the individual categories. Conclusion: The Research shows that nurses have a general maintenance of the roles and competencies, actually both of sides, Namibia and Czech Republic also. both groups were mostly able to define roles in nursing care. Surprisingly czech nurses most failed in the role of the Advocate, while African colleague have proven to be very informed. Research also showed negative effect of paperwork and administration in czech system. Nurses having feeling they do not provide active care as they would be able to. Czech nurses seems also low initiative and ambitious, Czech nurses do not desire for increasing competence on the other hand African nurses, who have more competencies, want still more, than they already have.
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