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Railway Crossings
Nováková, Anna-Marie ; Hoza, Miroslav (referee) ; Svoboda, Richard (advisor)
This bachelor thesis is focused on the railway crossings problem from the point of meaning of all available legislation. In this work I tried to find out whether all available legislative resources for railway crossings design are identical in their interpretation, as ambiguity of these resources could confuse drivers of vehicles and lead to the big number of traffic accidents. To solve this problem I analyzed all available legislative resources. I determined the most important chapters which context might be interpreted in a different way. Furthermore, I investigated which specific legislative resources deal with the problem and then compared it individually. By completion of this work I figured out that the most important chapters of existing legislative resources don’t contain ambiguity in railway crossing design.
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Prevention of civilization diseases by the eyes of generation 50+
NOVÁKOVÁ, Anna
Introduction: The diploma thesis deals with the topic of prevention of civilization diseases by the eyes of the generation 50+. The incidence of civilization diseases in the Czech Republic is still on the rise. Therefore, the timely and consistent prevention is essential, especially in the areas of healthy eating, appropriate physical activity, and prevention of stress or risky behaviour. Aim: The aim of this work is to point out the knowledge of generation 50+ in the Hradec Králové Region on the risks and prevention of civilization diseases, the generation's attitude to prevention, how they assess their health condition and how they describe their own lifestyle. Methodology: A qualitative approach using a semi-structured interview was used in the research. The research sample consisted of 24 informants at the age of 51 to 79 years. Of these, 16 were women and 8 men. Results: The results showed that the generation 50+ in the Hradec Králové Region has certain knowledge in the area of prevention. Most informants think that the civilization diseases are specific diseases, especially cardiovascular diseases, oncological diseases or diabetes mellitus. In the area of risk factors, the informants predominantly correctly included risk factors for the development of civilization diseases. The most frequently mentioned factors were the lifestyle risk factors, especially diet, physical activity and risky behaviour such as smoking or alcohol. Regarding the area of prevention, most informants think it is important, but not all informants go to regular preventive examinations or preventive screening examinations. The change of opinion on prevention in informants changes with age and after the diagnosis of a disease. Among the informants, the information concerning prevention is most often obtained from doctors, the media or the press and to a lesser extent from general nurses. In the area of health, most informants emphasize the condition of being painless, self-sufficient and mobile. In the area of lifestyle, the research shows that most informants are not interested in a healthy lifestyle very much. However, they try to observe certain principles of a healthy lifestyle, especially in the area of appropriate eating and physical activity. Conclusion: The results indicate areas of prevention about which people should be repeatedly informed and alerted to their importance and possible consequences if they do not observe them. In particular, it is important to place greater emphasis on primary prevention, especially on lifestyle in the form of appropriate diet, physical activity, stress prevention and risky behaviour. Equally important is secondary prevention and preventive examinations and preventive screening examinations, and tertiary prevention, with a focus on eliminating or mitigating the consequences of diseases and improving the quality of life.
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Horizontal transfer of mitochondria and its role in carcinogenesis
Nováková, Anna ; Neužil, Jiří (advisor) ; Rösel, Daniel (referee)
Mitochondria are essential organelles as they produce most ATP to support cellular activities, synthesize critical metabolic factors and are involved in lipid and phospholipid metabolism as well as calcium signalling. The oxidative phosphorylation (OXPHOS) system, present at the inner mitochondrial membrane, plays role in regulation of cellular metabolism and survival of cancer cells. Recent studies show importance of OXPHOS in growth of cancer cells via regulation of the de novo pyrimidine synthesis pathway. Dihydroorotate dehydrogenase (DHODH), a flavoprotein localized in the inner mitochondrial membrane, converts dihydroorotate (DHO) to orotate within the de novo pyrimidine synthesis pathway, generating electrons that are transferred, via redox- cycling of ubiquinone, to complex III (CIII) of respiratory chain. Since DHODH is functionally linked to CIII activity, impairment of respiration results in reduced activity of DHODH and pyrimidine synthesis. Therefore, mitochondrial damage or mutation in mitochondrial DNA (mtDNA) leads to decreased respiration, cancer cell proliferation and delay of tumour growth. As a compensation for damaged mitochondria, horizontal transfer of functional mitochondria from donor somatic cells to the mitochondria-damaged tumour cells was demonstrated. This...
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The specifics of Japanese management on the example of Mitsubishi Electric Automotive Czech, s.
Nováková, Anna ; Tureckiová, Michaela (advisor) ; Reichel, Jiří (referee)
In this thesis certain elements of the Japanese management model are examined in the context of Euro-Atlantic management model. As a single integral model of Japanese management does not exist, firstly, two groups of selected elements of Japanese management are explained in the theoretical part. The aim of this thesis is to analyze whether selected approaches of Japanese management have been applied at Mitsubishi Electric Automotive Czech s. r. o., and or how they have been modified in the Czech Republic. The first group of selected elements includes approaches in which active employees allow the organization to achieve high quality products and services - the strategy of kaizen, the activities of quality control circles and total quality management. Japanese management features that are included in the second group lead to the organization cost minimization. Particularly, this paper describes the just-in-time production, total productive maintenance concept, the technique of 5S, the technique of systematic elimination of wasting and the phenomenon of employee loyalty. Having realized a qualitative survey with seven respondents, the analysis showed that the chosen approaches in the organization have been applied, except for the quality control circles. The kaizen strategy has been narrowed down...
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Transformation of radio broadcasting in Pardubice after 1989 (in relation to Radio Profil)
Nováková, Anna ; Groman, Martin (advisor) ; Cebe, Jan (referee)
The goal of this work is to describe (on the basis of archival sources, topical newspapers and magazines, legal enactments and interviews with personal observers) the emergence of the first private radio station in Eastern Bohemia in the beginning of nineties. This is seen as an example of wider transformation processes within the whole Czech media area. The state owned and controlled electronic media were substituted by private (mostly commercial) media and the statutory public-service broadcaster.
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Social Business of NGOs
Nováková, Anna ; Krbová, Jana (advisor) ; Dvořák, Jiří (referee)
The subject of the thesis is the proposal of the work integration social enterprise (WISE) of NGO SOS Children's villages. Proposal shall take form of a business plan and is based on the needs of the Association to reduce its financial dependence on an external sources of funding. A business plan is a proposal of the concrete WISE which fulfils the function of an alternative financing instrument for the main activities of the Association. The thesis uses the method of SWOT analysis to group and evaluate the available information from the external and internal environment of the WISE as well as uses tools of economic and financial analysis to determine the tipping point and the financial needs for the operation of social enterprise in the first three years of operation. The thesis brings new results and knowledge and proposes a recommendation of how the social enterprise could be realized.
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Comparison of instruments of state support for exports in the Czech Republic and Spain
Nováková, Anna ; Nejedlý, Michal (advisor) ; Rotecker, Johannes (referee)
The work deals with the comparison of instruments of state support for exports in the Czech Republic and Spain. The first and the second chapter describe the current concept of pro-export policy of the Czech Republic and Spain and provide an outline of the economic situation in the country. Chapter three defines the system and the instruments of state support for exports. It focuses on export promotion institutions providing state support for exports in the areas of finance, insurance and non-financial services such as counseling. Chapter four compares the settings for the two systems, individual instruments, export promotion institutions and their products. The work reflects the current status of state export promotion in the Czech Republic and Spain.
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