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Cariovascular Profile, Level of Its Control in Relation to Complications in Type 2 Diabetic Patients
Nussbaumerová, Barbora ; Rosolová, Hana (advisor) ; Lacigová, Silvie (referee) ; Málková, Jana (referee) ; Soška, Vladimír (referee)
1. A sample of 415 type 2 diabetic (DM2) subjects was examined. The control of cardiovascular risk factors, e.g. blood pressure, lipids and glucose metabolism, is unsatisfactory in this sample. There is a lack in nonpharmacological treatment and regimen - physical activity, smoking, low energy diet. The choice of antihypertensive treatment is satisfactory. Many patients have only the monotherapy. The antihypertensives are underdosed. We are not sure about the compliance. The treatment of dyslipidemia is not sufficient enough, there is a lack of the statin + fibrate combination therapy. The nonpharmacological regimen in needed for better glucose metabolism compensation. The pharmacotherapy should be indicated earlier (esp. metformin). 2. The prevalence of microvascular complications (mvc) was high in this sample (54%), especially the diabetic nefropathy (95%). The macrovascular compliactions (MVC) were present in 27% subjects, more in men, 55% of them had coronary heart disease. Subjects with MVC had more often mvc. The risk profile was worse in subjects with any vascular complications. The common risk factors in association with both MVC and mvc were the age over 60 years and hsCRP plasma level over 1 mg/L. We follow the sample prospectively to estimate predictive factors for vascular complications. 3. We...
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Working load: nuclear power plant control room
Rounová, Kateřina ; Buriánek, Jiří (referee) ; Mudd, Dana (advisor)
This work is focused on problems concerning woking load in theory as well as in practise. In the theoretical section we define basic terminology, describe risk and protective factors, metods of evaluation and other aspects connected with this issue. Moreover, we apply the subject of this work to the field of practice. In the empirical part we describe a real screening project related to working load at an exposed workplace - nuclear power plant control room. The work results in practical suggestions that could be followed by further projects.
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Risk Analysis and Evaluation in a Transporting and Haulage Firm
Čegan, Tomáš ; Máša, Votěch (referee) ; Adamec, Vladimír (advisor)
This diploma thesis deals with an analysis and evaluation of risk in the freight transport company – Doprava Vícha s. r. o. The thesis describes the current situation in a freight transport industry, an applicable legislation, and risk analysis methods FMEA and WHAT-IF. Further the thesis analyses risks of a freight transportation and describes the company Doprava Vícha s. r. o. in detail. The thesis proposes a set of actions in order to minimize identified risks. The handbook with most important actions and advices for drivers is attached.
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Title of the Master´s Thesis
Sečkárová, Adriana ; Vrbová, Lucie (advisor) ; Hájek, Jiří (referee)
The goal of ZOFF is formulated as a change of stagnation and increase in annual profit in term of 2 years, provided adequate low risk. The paper describes the outcomes and conclusions from a marketing research that highlights the key attributes of the company and its target audience. Way out of the situation lies in identifying the problem and its subsequent formulation. To achieve the objective are used various methods of creation and comparison of the criteria which define variants created. This process comprises a decision matrix for identification and comparison of risk scenarios. The output of the work is to evaluate and compare the resulting variants and recommendation to the elimination of possible threats.
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Problems posed by the protection of lamprey and fish localities of European importance in the drainage areas of the Dyje, Morava, and Odra rivers
Lusk, Stanislav ; Lusková, Věra ; Lojkásek, B. ; Halačka, Karel
In consequence of the accepted legislation concerning the protection of lamprey and fish species of European importance, potential sites of community interest (pSCI) have been selected for such species. At present, the national list of the proposed pSCI is being examined by the European Commission. If approved upon, the pSCI will be proclaimed "special areas of conservation" within the NATURA 2000 system. Although such pSCI and their populations are protected by legislation, there occur risks that endanger, both directly and indirectly, the quality of the pSCI and the population of the particular species. The examples mentioned in the paper indicate that such risks include local emergency pollution, construction of weirs and small hydraulic power plants, extraction of sediments from streambeds, cruising vessels, and stream modification. Such risks are due to the inconsequence and reluctance in observing the legal protection measures by concrete authorities of nature conservation.
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Integration of the Financial Markets of the New Member States of the EU
Chaloupka, Jiří ; Taušer, Josef (advisor) ; Záklasník, Martin (referee) ; Varadzin, František (referee)
The subject of the thesis is the integration of financial markets of the new member states of the European Union (hereinafter referred to as the NMS). According to the standard economic theory, the process of financial integration should be associated with several positive effects, among others a) the enforcement of the law of one price in the form of the interest rate parity, b) the smoothening and the synchronisation of the consumption growth among countries, c) the increased diversification of investors portfolios, and d) the decreased dependence of domestic investments on national savings. These envisaged effects serve in the thesis as the indicators of the integration of NMS financial markets with the global financial market. These indicators show that the degree of the financial integration differs among the NMS, despite the fact that they all went through the process of integration with the EU. However, the order of the NMS based on the degree of their financial markets integration could not have been determined as each test indicated a different order. However, most tests indicated that there is a trend towards more integration of the NMS financial markets as the dependence of the domestic consumption growth on the global consumption growth has been increasing and the dependence of domestic investments on national savings has been decreasing. Surprisingly, the indicators did not prove the hypothesis that NMS financial markets are more integrated with the financial market of the EU, despite the fact that these countries had to open their markets to investors from the EU and had to harmonize their legislative requirements. Contrary to the results of previous articles, indicators used in the thesis show that majority of the analysed puzzles in international economics disappeared for large developed markets like the USA. On the other hand, these puzzles persisted for the NMS. Given that majority of the NMS adopted euro during the period under investigation, results presented above indicate that the financial markets of the NMS were not fully integrated with the financial market of the EU and therefore one of the conditions for the existence of the optimum currency area has not been met. Such result also contradicts the hypothesis of the endogeneity of the optimum currency area as the adoption of the common currency did not improve the degree of financial market integration.
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Model CAPM
Burianová, Eva ; Pošta, Vít (advisor) ; Nováček, Jan (referee)
Cílem první části této bakalářské práce je - pomocí analýzy výchozích textů - teoretické shrnutí ekonomických modelů a teorií, na kterých model CAPM stojí: Markowitzův model teorie portfolia (analýza maximalizace očekávaného užitku a na něm založený model výběru optimálního portfolia), Tobina (rozšíření Markowitzova modelu ? rozdělení výběru optimálního portfolia do dvou fází; nejprve určení optimální kombinace rizikových instrumentů a následná alokace dostupného kapitálu mezi tuto optimální kombinaci a bezrizikový instrument) a Lintnera (alternativní přístup k separačnímu teorému). Ve druhé části popíši samotný model a jeho dnešní podobu. V poslední části budu vycházet z empirických studií E.Famy a K.Frenche a zhodnotím nedostatky modelu ? konkrétně vypovídací schopnost koeficientu beta, aproximaci tržního portfolia a předpoklad efektivnosti kapitálových trhů.
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Optimální portfolio
Menčík, Tomáš ; Musílek, Petr (advisor)
Tato práce si dává za úkol stanovit optimální týdenní portfolio složené z burzovních indexů s přihlédnutím k měnovému riziku a zpracovává data vývoje jednotlivých indexů i směnných kurzů od roku 1999. Optimální portfolio jsem zkoumal z hlediska investora v amerických dolarech, eurech a českých korunách. Na základě analýzy výsledků jsou stanoveny faktory, které rozhodujícím způsobem ovlivňují složení portfolia.
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A growth maximizing contrarian trading strategy
Janča, Marek ; Krištoufek, Ladislav (advisor) ; Havránek, Tomáš (referee)
Účelem práce je vytvořit obchodní strategii, která by využívala jevu "contrarian profitability". První část práce se věnuje samotnému odvozování strategie. Nejprve využijeme faktu, že strategie maximalizuje růst, právě pokud v každé periodě maximalizuje logaritmus hodnoty našeho bohatství. Poté log-optimální portfolio approximujeme portfoliem, které leží na efektivní hranici (termín z oblasti moderní teorie portfolia). První a druhé podmíněné momenty specifikujeme pomocí dynamického ekonometrického modelu. V druhé části prodiskutujeme nedostatky naší strategie a pomocí Monte Carlo simulací ji modifikujeme. V závěrečné části demonstrujeme životaschopnost strategie na historických datech. Za předpokladu neomezené páky a rozumných transakčních nákladu jsme byli schopni dosáhnout průměrného ročního zhodnocení kolem 24%.
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Investment decisions on the PSE
Kolaříková, Klára ; Borovička, Adam (advisor) ; Kuncová, Martina (referee)
This thesis deals with the investment decision on the Prague Stock Exchange (PSE) in the SPAD system (System to support the market shares and bonds). Introduction belongs to financial markets and important institution, which is a part of the financial market - stock exchange. We describe an environment of the Prague Stock Exchange (PSE), where are realize the investment decisions. An extensive section is devoted to the theory of decision making, specifically discrete models of multiple criteria decision making and continuous models of decision making, which includes linear programming and the special role of the target programming. In the practical part of thesis, all these methods are used for calculating the optimum composition of the portfolio for the investor. The target of the thesis is to determine the final composition of the portfolio investment recommendations, in order that an investor from the investment decision had the greatest benefit.
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