National Repository of Grey Literature 27,502 records found  beginprevious27493 - 27502  jump to record: Search took 1.63 seconds. 

Trends in the CRM business information systems
Valenta, Martin ; Basl, Josef (advisor) ; Novotný, Ota (referee)
The purpose of this thesis is to analyse the trends related to the Customer Relationship Management (CRM) with emphasis on the CRM software. Essential trends were identified through professional analytical reports and dedicated servers. CRM trends were analysed from the time and factual perspective. The core purpose of this thesis was to evaluate possible business value of identified trends for businesses from a selected market segment. To fulfil this goal, the banking segment was chosen to be further analysed. The author of this thesis studied the extent of implementation of chosen trends in a real CRM implementation project executed in a bank operating on the market of Czech Republic. In the process, the set of interviews with "CRM in banking sector" professionals were completed to figure out how they are possibly appreciated by the whole banking sector. Through the responses of the chosen professionals, some trends characteristics were mainly followed. These were trend maturity (captured by slightly modified Gartner Hype Cycle) and trend business value (captured by defined numeral evaluation). An average evaluation of business value of each trend, done from various time perspectives, was displayed by two different tables, each grouping trends on the factual basis. Finally, trends business values were represented graphically to accent their possible progress as seen from the banking sector point of view and to provide users with a simple tool to confront their view with the view of the professionals. The tool mentioned allows users to focus on the trends that are likely to be very beneficial (according to the general opinion of the chosen professionals) and at the same time allows users to stay clear of the trends that don't promise much value for the banking sector, not even in the future.

Working professional insurance agent training
HAMERNÍKOVÁ, Šárka
The goal is to develop a training program that will allow insurance agents to cope with abnormal situations associated with insurance. In the beginning is get you started in the theoretical issues of insurance, insurance agents, skills and characteristics of individuals operating in this area. Furthermore, the study points to the importance of training, knowledge, skills, modify attitudes, social action agents. The main part is developed job training, to contribute to the achievement of the objectives and requirements of insurance. In the end, provide appropriate practical recommendations for insurance brokers and insurance companies.

Chromatin modifiers and their relation to transcription regulation in Saccharomyces cerevisiae
Hálová, Martina ; Folk, Petr (advisor) ; Staněk, David (referee)
Relations among transcription, pre-mRNA processing and chromatin modifications are only partially understood. The human protein SNW1/SKIP belongs to factors which couple these processes. The protein plays role in pre-mRNA splicing and transcription on the level of both initiation and elongation. According to the hypothesis of K. Jones laboratory, it physically and functionally interacts with positive transcription elongation factor b during transcription elongation and influences methylation of histone H3 on lysine 4, a modification characteristic for active transcription (Bres et al., Genes Dev. 19:1211-26, 2005, Bres et al., Mol Cell. 36:75-87, 2009). The yeast ortholog of SNW1/SKIP, Prp45, was until now reported only in connection with splicing regulation. However, unpublished results from our Laboratory and others showed that it is employed in transcription elongation as well. The aim of the diploma project was to search for the relations between Prp45 and the factors regulating transcription. It was confirmed that the mutation prp45(1 169) results in the delay of PHO5 and PHO84 expression during transcriptional induction. Next, we discovered new genetic interactions between PRP45 and several genes encoding the effectors of chromatin modifications. How Prp45 influences the expression of PHO5 and PHO84...

The analysis of the structure of music festivals´ visitors and new festival project
ŠERPÁN, Adam
The master thesis analyzes the structure of multi-genre music festivals´ visitors and on the base of this analysis, a part of marketing mix of concrete festival is proposed to be modified. This modification is primarily focused on communication mix. Music festivals are the product of tourism. This is one of the essential ideas of this master thesis. Festival is a service - nonmaterial product, so there must be reached the maximal efectivaty of the communication with the music festival customer - visitor. The secondary goal of the master thesis is proposal of the realizatoion of multi-genre music festival in České Budějovice. This goal is almost achieved, when local authority has expressed the agreement with this project.

Spacetimes with photon rockets
Kolář, Ivan ; Podolský, Jiří (advisor) ; Krtouš, Pavel (referee)
In this work we study exact spacetimes that represent the gravitational field of a localized object accelerating due to an anisotropic emission of photons - pho- ton rocket. First, we describe general properties of the Kinnersley and the Bonnor rocket, which both belong to the family of Robinson-Trautman spacetimes. Sub- sequently, we summarize two main approaches to the study of asymptotically flat spacetimes: the Bondi-Sachs and the Penrose methods, combined and modified by Tafel and Pukas in recent papers. We compare the mass aspect of the Robinson- Trautman spacetime obtained by both methods, and generalize thus the relation found by von der Gönna and Kramer. Next, we calculate the energy-momentum vector, the Bondi rest mass, and the "news tensor for the arbitrarily moving Kin- nersley rocket. By using these results, we naturally define the velocity vector of the rocket with respect to the Minkowski "background spacetime. We conclude with the physical interpretation of the Kinnersley rocket in various reference fra- mes.

Possibilities of utilization of brick-grind-dust in systems based on portland cement
Palovčík, Jakub ; Kalina, Lukáš (referee) ; Opravil, Tomáš (advisor)
This thesis deals with possibilities of using brick-grind-dust which is a secondary product from manufacturing of grinded bricks. A boom in this method of masonry is connected with an increase of production of these secondary materials. These secondary materials are partly returned to brick manufacturing and partly buried in a landfill site. Due to their composition and origin, these materials are potentially pozzolan active, making them interesting for applications in hydraulic binders. The aim of the work was to study the physical and chemical properties of several brick-grind-dust and brick sands. Subsequently, binders based on these materials and Portland cement were prepared. The properties of the binders were modified by means of adding a commercially available polycarboxylate superplasticizer. The development of mechanical properties of the prepared binders has been studied over time. Hydration of the selected binders was analyzed by isothermal calorimetry.

Study of genetic factors modifying the risk of onset and progression of colorectal and pancreatic cancer
Mohelníková Duchoňová, Beatrice ; Souček, Pavel (advisor) ; Skálová, Lenka (referee) ; Macek, Milan (referee)
Introduction: The aim of this study was to evaluate the role of genetic and lifestyle factors in the risk of onset and progression of colorectal and pancreatic cancer. The first part deals with the etiological factors and the importance of polymorphisms in biotransformation enzymes and genetic alterations in the gene CHEK2 in the origin of these malignancies. In the second part, the ABC transporter genes were analyzed as potential prognostic and predictive markers of a treatment's outcome. Materials and methods: The polymorphisms and other genetic alterations were detected using real-time PCR, allelespecific PCR and PCR-RFLP methods in DNA which was extracted from the blood of patients. The frequency of polymorphisms was evaluated and their importance was assessed with regard to the available epidemiological data. Gene expressions were determined by qPCR in paired samples of tumor tissue and adjacent non-tumorous parenchyma. Results: A majority of the observed polymorphisms failed to show a relationship between their presence and the risk of any of these malignancies. CYP2A13 variant allele*7 coding inactive enzyme was found in 7 of 265 controls and in none of 235 pancreatic carcinoma patients. In contrast, GSTP1-codon 105 Val variant allele and GSTT1-null genotype were associated with an elevated...

Genetically modified organisms and the legal regulation of their disposal
Musilová, Kristýna ; Žákovská, Karolina (advisor) ; Stejskal, Vojtěch (referee)
This thesis aims to give a complex insight into the framework and problem questions arising in connection with legal regulation of genetically modified organisms (hereinafter referred as "GMOs"). As the use of GMOs is spreading it brings along many discussions regarding their positive and potential negative impacts on human health and the environment. After the introduction into the GMOs from the practical and technical point of view, the analysis of the underlying principle, the precautionary principle, follows. Different approaches to the risks connected with GMOs formed different views on construction and application of the precautionary principle and caused its uncertainty as to its position in international law. Significant part of the international law relating to the GMOs consists of soft law documents. The willingness of states to be bound by binding rules in this area is still lacking. The only exception is the Cartagena Protocol on Biosafety focusing on the transboundary movement of GMOs. The Law of European Communities comprises of Regulations, Directives, and Recommendations. The law distinguishes following types of use: contained use, deliberate release of GMOs into the environment for any other purpose than for placing on the market, release of GMOs on the market and transboundary movement....

Redesign of information systems in multimedia laboratory(GML) on VSE
Burda, Adam ; Horný, Stanislav (advisor) ; Krsek, Libor (referee)
This paper aims to describe and propose solutions to problems impairing the functionality of the Prague School of Economics' Graphics and Multimedia Laboratory (GML). The problems to be solved arise in the current information technology devices, more specifically in data back-up, usuitable hardware and lan connection as well as missing software. Finally, the paper discusses the idea of puchasing devices to be used outside the GML. The multimedia laboratory is concerned with issues relating to graphics creation and video adjustment. The solution put forward in this paper proposes using specific hardware designed for editing and graphics applications. While an effort is made to seek a multiple solution, the proposed adjustments require purchasing new hardware and software which are innovative if rather costly. Financially demanding as those are, both the optimal and the more budget-friendly options are introduced. Finally, an overview table summarises the costs, supplemented by detailed calculations. The solutions proposed are based on generally accepted procedures. These are modified in view of the author's experience of network administration and devising specific coputer systems.

Analysis of transportation problem with bounded variables
Klasová, Petra ; Kalčevová, Jana (advisor) ; Šmídová, Milada (referee)
This bachelor thesis introduces the transportation problem with bounded variables, methods design and practical application of these methods on fictive data. The examples demonstrate the algorithm of optimal solution calculation. This thesis describes the modification of the north-west corner method, index method and Vogel's approximation method for problems with bounded variables, as well as the distribution and modified distribution method.