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Stability of humic acids in production of eye drops
Lišková, Kateřina ; Mravec, Filip (referee) ; Bilerová, Helena (advisor)
Glykoaminoglykans are the biological active compounds, which significantly affect the physiological processes in living organisms from under low concentrations. Marked representative of this group is hyaluronic acid. It is linear polysacharid, whose primary structure is consists of D-glucuronic acid and N-acetyl-D-glucosamin linking by glycosidic bonds (13) and (14). It is occurring connective tissues, synovial fluids and vitreous humor too, in which forms system with unique rheological and optical properties. Except of human body is its concentration especially high in the cockscombs. Hyaluronic acid has very high ability to bonding molecules of water, increasing molecular weight a then viscosity of aqueous solutions too. This fact together with characteristic viscoelasticity and lubricating properties plays an important role in preserve of organism. Acid, but its salt too form basic component of compounds using in ophthalmic surgery. It is using in extraction of cataract, operation of glaucoma, implantation of crystalline lens and corneal grafting too. Aim of this bachelor work was a determination of stability of hyaluronic acid solutions along the production of eye drops. Main objective was using by rheological measurement detect the influence of addition polymers (PVP, PACA, PEOX, PEG, PUD, PEI) and different pH on stability, degradation aqueous solution of hyaluronic acid at sterilization in the steam autoclave respectively.
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Major Events of the 20th Century as Recorded in Chronicles of Multi-grade Schools in the Area of Trhové Sviny and Nové Hrady
MÍČKOVÁ LIŠKOVÁ, Kateřina
The diploma thesis deals with the possibilities of teaching the educational field of Man and his world, the subject of homeland studies in the 4th and 5th year of primary school. The theoretical part defines the terms Multi-grade schools, clarifies the history and meaning of school chronicles and deals with the definition of the educational area Man and his world in the Framework Educational Program for Primary Education. It also characterizes the area of Trhové Sviny and Nové Hrady, whose historical network of small schools is the starting point for the practical part of the thesis. The practical part of the diploma thesis deals with the analysis of the content of school chronicles of selected Multi-grade schools, the analysis of the content of textbooks and the method of oral history in terms of the possibility of use in teaching homeland studies. Furthermore, the practical part introduces the proposals for the use of these materials and methods in teaching.
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The utilization of atomic force microscopy for study on hydrogels
Lišková, Kateřina ; Kalina, Michal (referee) ; Smilek, Jiří (advisor)
The presented bachelor thesis deals with the study of atomic force microscopy (AFM), especially the optimization of the measuring procedure for imaging the surface of variously crosslinked hydrogels in the hydrated state. The most attention was given to the physically crosslinked polysaccharide hydrogel (termoreversible agarose) in hydrated state, where the surface of the samples with mass concentration of 4, 2, 1, 0,75 and 0,5 % was measured. Subsequently, the surface of the ionically crosslinked 2 % alginate gel with calcium ions was measured. Based on a literature research, measurements were performed in water using the method of quantitative imaging (QITM Advanced Imaging), which is especially suitable for soft samples with uneven surfaces. Multiple cantilever were tested for measurement, finally the SNL-10 cantilever was selected, which showed versatility for imaging samples in any measuring environment, especially aqueous. The pore sizes of the agarose hydrogels were monitored by image analysis ImageJ. For the measurement of hydrogels in the swollen state, the procedure of measuring their surface using atomic force microscopy has been optimized, but for different types of hydrogels, individual optimization of both preparation and instrument setup will be required.
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Sign Language Translation in State Administration in Germany: Barrier Free Web Accessibility
Lišková, Kateřina ; Stará, Radka (advisor) ; Nováková, Radka (referee)
The aim of this thesis is to describe Web accessibility in state administration in the Federal Republic of Germany in relation to the socio-demographic group of deaf sign language users who did not have the opportunity to gain proper knowledge of a written form of the German language. The demand of the Deaf to information in an accessible form as based on legal documents is presented in relation to the theory of translation. How translating from written texts into sign language works in practice shows an example from two sign language translation providers in Germany. In conclusion, the visually accessible information on the Web might have an impact on the quality of Deaf people's lives. Keywords: translation, sight translation, interpreting, deaf interpreter, German Sign Language, Federal Republic of Germany, freedom of information, deaf, people with hearing loss
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Quality of Life, Satisfaction with Life, Social Self-efficacy and People after Acquired Brain Injury.
Lišková, Kateřina ; Šivicová, Gabriela (advisor) ; Kebza, Vladimír (referee)
This thesis is focused on quality of life theme, satisfaction with life topic and social self- efficacy subject, with emphasizing of the acquired brain injury context and specific and unique brain injury consequences. Thesis is based on theoretical fundament of all mentioned concepts, but mainly there are actual quantitative data and results of quality of life, satisfaction with life and social self-efficacy and other-efficacy in the framework of acquired brain injury research sample in Czech Republic. Not only description of quality of different life parts subjective perception, but also search of possible relationships strength between quality of life and social efficacy has been probed. All of these has been used in application of lots of standardized and also new questionnaire and methods. Keywords: acquired brain injury, quality of life, satisfaction with life, social self-efficacy, social other- efficacy
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Options of "Employing" of Volunteers in Czech Public Libraries
Lišková, Kateřina ; Drobíková, Barbora (advisor) ; Stöcklová, Anna (referee)
The main target of this diploma thesis is to focus on the area of volunteers in libraries and librarianship, mainly in the Czech Republic and try to summarize the voluntary tasks or services in these public institutions. Firstly, the text tries to explain the main ground and principles of volunteering, also the historical background and terminology. Secondly, the thesis deals with the voluntary network, their centres, reflexion, motivation and legislation. The main part focuses on the comparison of German and Czech faces of volunteering in the libraries and the results of questionnaire done in the chosen Czech libraries are presented and commented. The conclusion includes all received knowledge and information and outlines the potential possibilities of the usage of volunteers in libraries and public sector in the Czech Republic (including suggested working tasks volunteers can be used for). [Author's abstract].
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IL-25: Novel target to treat allergic diseases
Lišková, Kateřina ; Hrdý, Jiří (advisor) ; Boháčová, Pavla (referee)
Interleukin (IL) 25 is a proinflammatory cytokine that promotes a Th2-type cell response. Its alternate name is IL-17E, and along with 5 other members, IL-25 belongs to to the family of cytokine IL-17. The family is based on the similarity of their amino acid sequences. The source and target cells of IL-25 include many different cell types. IL-25 is not only produced by many types of immune cells, but epithelial and Paneth cells are involved in its production as well. Its receptors form heterodimers composed of 2 subunits - IL-17RA and IL-17RB. Both receptor proteins are required for IL-25 mediated activities and occur in other IL-17 family members. IL-25 also plays an important role in allergies - one of the most common diseases in developed countries. Cytokine IL-25 has been studied primarily in asthma. However, other very common types of allergies, such as food allergies, atopic dermatitis and allergic rhinitis, can not be overlooked. Even in these cases, the role of IL-25 is not negligible and is studied. Based on the knowledge of IL-25 biology and its role in allergies, this cytokine may be an important therapeutic target in the treatment of allergic diseases. One possibility is, for example, the use of neutralizing antibody and subsequent blocking of IL-25 activity. Key words: interleukin-25,...
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Crisis intervention via electronic communication (on-line chat, on-line videochat)
Čechová, Kateřina ; Havránková, Olga (advisor) ; Lišková, Kateřina (referee)
This diploma disertation deals with the topic of on-line crisis intervention (KI further on in the text) in the Czech Republic (CR), specifically the service functioning of the online chat and videochat. This topic has not been paid attention to so far. The topic concerned is a rather new service area which provides service to the clients in a difficult situation on the internet and which has been working for past few years in a few KI centres (workplaces). No professional has tried to search it systematically or describe it in more detail yet. Considering the fact the internet is a widely used medium in our population nowadays, a high future potential of these services can be expected in the field of psychosociology. Therefore this diploma disertation aims to give a detailed description of the on-line chat and videochat functioning and necessary connections at KI centres (workplaces) in order to create a quidebook to the basics of these services for specialists and amateurs who are interested in this topic. Secondly, this diploma disertation is written to inform about the process of implementing the on-line chat into KI centres (workplaces) at three contemporary providers in CR, and to make the readers understand what the whole process is about. At the same time, this is to compile all the data for a...
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Study of decomposition of organic matter in soil using the method of "tea bags"
Lišková, Kateřina ; Sedláček, Petr (referee) ; Enev, Vojtěch (advisor)
The main aim of this master thesis was to introduce an optimal method which could be used for study of a decompostion of an organic matter in a soil. For this purpose was chosen based on a literaly review so-called tea bag method. With regard to the completeness of the work, a physico-chemical characterization of the soil environment and HS isolated from it was also performed. The degraded organic material was then further characterized using thermogravimetric analysis, elemental analysis, FT-IR spectroscopy, and the total content of water-extractable polyphenolic substances in the samples was also determined.
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