National Repository of Grey Literature 90 records found  1 - 10nextend  jump to record: Search took 0.01 seconds. 
Preserved monastery gardens in Lesser Town of Prague
Pulcová, Veronika ; Altová, Blanka (advisor) ; Pešek, Jiří (referee)
The subject of this thesis is a description of the current state and a retrospective view of the history of the preserved monastery gardens in the context of the urban development of the Lesser Town. Specifically, these are the gardens that have survived at the Grand Priory of the Knights of Malta at the Church of Our Lady under the Chain, the garden of the Oblate Augustinians at the Church of St. Thomas, the garden of the Dominicans (formerly Magdalenites) at the former Church of St. Mary Magdalene, the garden of the Barefoot Carmelites at the Church of Our Lady of Perpetual Help, the Theatines (Cajetans) at the Church of Our Lady of Consolation, the Jesuit garden at the Church of St. Nicholas, the garden of the Convent of the English Maidens at the Church of St. Joseph (Vojanovy sady) and the garden of the Sisters of Mercy of St. Borromeo under Petrin. I describe the current state of the individual gardens and retrospectively trace their historical transformations in an urban context.
Sequences forming G-quadruplexes in the amyloid beta precursor human gene and its homologues
Stránská, Anna ; Šedrlová, Zuzana (referee) ; Brázda, Václav (advisor)
The APP gene encodes the transmembrane protein amyloid beta precursor, which is expressed in many cell types, including neurons. Its functions have not yet been fully described, but it is clear that it is being cleaved before being exported to the extracellular space. It is degraded by various degradation pathways also undergoes homodimerization, which can produce particles with protective neuronal function as well as fragments that are toxic and cause nerve cell death. The formation of harmful amyloid beta plaques and their accumulation among neurons in the brain is closely linked to the onset and progression of Alzheimer's disease, a neurodegenerative brain disease manifested by death and loss of neurons, which leads to dementia, i.e. loss of cognitive functions. There is currently a lot of research that deals with the links between neurodegenerative diseases and the occurrence of G-quadruplexes in genes that are involved in disease manifestations. G-quadruplexes are non-canonical DNA and RNA nucleic acid secondary structures that arise in guanine-rich regions. They are important mainly in terms of their connection with biological processes such as the regulation of gene expression in genes and mainly in oncogenes because they occur in important regions of the gene such as the promoter. It is possible to stabilize them with small molecules, and it is this ability that is used in research into the therapeutic treatment of various diseases. A bioinformatics analysis of both the human gene and 346 other gene homologs was performed to determine the importance of G-quadruplexes localization and conservation in the human APP gene. For this purpose, the G4Hunter program was used, which provided information about the found sequences with the potential to form a G-quadruplex, such as their location or G4Hunter score. In vitro analysis was performed using thioflavin T reagent, which tested the ability of the found sequences to form G-quadruplexes under physiological conditions. The results confirmed the presence and evolutionary importance of G-quadruplexes found in the APP gene of Homo sapiens and their ability to assemble into quadruplex structures in the presence of salts such as sodium and potassium.
On farm conservation of obsolete cultivars and landraces methodology
Holubec, Vojtěch ; Janovská, Dagmar ; Papoušková, Ludmila
This methodology defines basic terminology connected to on-farm conservation, presents links to international agreements and legal documents and describes its participants. There are presented possible practices of conservation based on experience in Europe, especially ECPGR, FAO and international projects focused on this topic. It proposes the system of on-farm conservation in the conditions of the Czech Republic as well as possibilities of its integration to international/European networks.
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The Food Conservation in Roman Italy
Benková, Martina ; Titz, Pavel (advisor) ; Ondřejová, Iva (referee)
This document deals with problems of food preservation in the ancient world focusing on Roman Italy. Attention is concentrated on individual conservation practices, covering the techniques of storage and direct preservative interventions, which include dehydration, salting, sweetening, pickling, smoking or making of diary products. The work is mainly based on the study of contemporary literary works particularly Latin agricultural handbooks dating from the 2nd century BC to the 6th century AD. The information obtained is supplemented to the maximum extent by iconographic sources and archaeological evidence of individual installations and their products. The result is a comprehensive overview of preservation methods, divided into categories and subcategories based on used technology approaches characterized in the introduction to each chapter. Powered by TCPDF (www.tcpdf.org)
Surviving of Northern Lapwing (Vanellus vanellus) chicks in agriculture landscape
Kubelka, Vojtěch ; Šálek, Miroslav (advisor) ; Cepák, Jaroslav (referee)
The variability of egg-size within a bird species reflects different reproductive investments and, besides the intrinsic constraints and particular female quality, it can be affected by environmental factors, too. Moreover, the egg-size predetermines the chick performance. The knowledge of factors influencing precocial chick survival is crucial for better understanding of life-history strategies as well as for endangered species conservation. The Northern Lapwing (Vanellus vanellus) represents a suitable model species for investigation of climate variables effects on egg-size and also to study factors influencing chick survival. Eggs in a total of 714 nests were measured during 13 breeding seasons over period 1988-2014 in South Bohemia and 293 lapwing chicks from 100 broods in 37 localities were monitored in 2013-2014. The mean egg-size through the whole season is positively affected by March precipitation, March clutches also negatively by minus temperatures in March. The higher intensity of rainfall there is during March, the bigger eggs are laid in March and the steeper is slope of decline in mean egg-size during season. This decline is more profound with lower rainfall in April. The effect of habitat is not significant. The body mass and condition of hatchlings is positively correlated with the...
RNA secondary structure conservation identification module for rPredictor
Pešek, Jan ; Hoksza, David (advisor) ; Škoda, Petr (referee)
The issue of comparing ribosomal RNA secondary structures is currently an open research problem. Goal of this work is to design and implement program comparing so called mutual conservancy of a group of rRNA secondary structures. This program is included as a new module of an existing system called rPredictor consisting of the structure database and an algorithm that predicts these structures. This thesis covers an introduction into the problem of secondary structures conservancy identification and summarizes known approaches towards the problem. The result of this work is a stand alone program for the secondary structure comparison and also a new analytic module of the rPredictor system, where the secondary structure comparison program can be used for comparison of the structures from the rPredictor database. Powered by TCPDF (www.tcpdf.org)
Lepidoptera Community of the Woodland Complex Loučany near Klatovy
Rendlová, Veronika ; Heřman, Petr (advisor) ; Hanel, Lubomír (referee)
This thesis is focused on faunistic survey of Macrolepidoptera in Loučany (foothills of the Šumava Mts, Czech Republic). The research, involving different capture methods, proceeded from April to November 2015 on given transect and several other habitats. Based on the results (including partial data from 2013 and the last two decades of the 20th century), an inventory of identified species of Macrolepidoptera was made. Altogether 205 species from 16 families were found in Loučany. The most important species are for example the Black-veined White (Aporia crataegi), High Brown Fritillary (Argynnis adippe), Pearl-bordered Fritillary (Boloria euphrosyne), Purple Emperor (Apatura iris), Spruce Carpet (Thera britannica) and Sandy Carpet (Perizoma affinitata). The environmental parameters of experimental sites were noticed during research and the habitat preferences of species were analysed using specialized literature. Altogether 186 species (90,7 % of all identified species) are linked to some kind of woodland habitat. To support present biodiversity of the community of Macrolepidoptera, it is necessary to practice a suitable woodland management, conserving mosaicity and open canopy. Key words: Lepidoptera, species diversity, Czech Republic, Klatovy area, conservation, woodland management
Villa Müller versus Villa Tugendhat - A Comparison of Two Different Restoration Projects of Modernist Buildings
Ksandr, Karel ; Biegel, Richard (advisor) ; Lahoda, Vojtěch (referee)
1 English abstract: Villa Müller versus Villa Tugendhat - A Comparison of Two Different Restoration Projects of Modernist Buildings. The work compares two successful restorations of interwar Czechoslovak avant-garde buildings realized between 1995 and 2012. At first, the respective histories of both buildings are compared since their creation through two totalitarian regimes up to their restoration. The fates of builders and architects of both villas are also described. From the point of view of historic preservation the work describes the state of both buildings before the commencement of restoration. The errors committed by the original designers are also described here. The methodology of restoration of both villas stemming from the professional points of view and relevant laws governing heritage protection is also treated in detail. The emphasis is given on preparation works preceding the design phase - the historic-structural survey, which, in both cases, was conceived as above-standard. Due to their span, these surveys have marked a key moment in relation to the modern cultural heritage within the Czech context. In the last part of the work links and comparisons are given to similar modern cultural heritage objects abroad. The work also documents the influence these two restorations have had on...
Social motivations to conservation of nature in the Czech Republic until 1956: the analysis of selected (protected) areas
Léblová, Kateřina ; Rynda, Ivan (advisor) ; Pojer, František (referee)
15 Abstract The main focus of this thesis is to discover psycho-social motivations leading to nature preservation. During the research almost a hundred of (protected) areas were selected and subsequently analysed to determine what variety of psychological/social motivations are decisive for preserving the nature in the Czech Republic. The localities were selected in the way that each region of the Czech Republic is being represented. The work explores a period since the beginning of purposeful preservation activities (circa 1800) until 1956 when the first Law on Protection of Nature was adopted by a socialist government. The objective is to categorize revealed motivations and to determine their significance as well as to find the most common initiators and scopes of environmental protection. Based on the results we shall be able to define tactics for the encouragement of civic and private activities. This revival could subsequently lead to a further protection of nature, to enhance interest in local events and to take responsibility for the condition of the environment. This research acknowledges what kind of environmental objects will most likely be protected in the future, what initiators are most often involved or whether education is of great importance. Key words Nature conservation, protected area,...
Podlepování historických textilií: Metodika projektu Ministerstva kultury ČR NAKI II „Vývoj metod podlepování historických textilií“
Krejčí, Jan ; Škrdlantová, Markéta ; Drábková, Klára ; Bureš Víchová, Jana
Metodika doporučuje a popisuje konkrétní metody podlepování vhodné pro konzervování-restaurování historických textilií, a to s využitím v současné době dostupných adheziv a podkladových materiálů. Doporučení jsou v práci podložena výsledky rozsáhlého výzkumu, který byl proveden na Ústavu chemické technologie restaurování památek na Vysoké škole chemicko-technologické v Praze.
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