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The Gargoyle
Čížek Uxová, Nikol ; Lukášová, Helena (referee) ; Helia De Felice, Jennifer (advisor)
Appropriation Gothic to contemporary art , in the form of temporary site-specific installations in the cellar. Installation consists of four separate pieces, which combines a common theme , which is based on his own experience and creates its own temple environment .
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Evaluation of industrial heritage
Navrátil, Oldřich ; Králová, Eva (referee) ; Zemánek, Václav (referee) ; Ryšková, Michaela (referee) ; Zemánková, Helena (advisor)
The main subject is evaluation of effective use in terms of care (not only within protection of monuments) in order to save and protect industrial heritage. Pointing out on critical issues connected with the end of production of traditional branches which played the key role in historical development of our cities. Nowadays abandoned buildings and sites are represented by memory of the place or its prosperity. New owners often don't share the positive approach to the industrial heritage, developers are seeking new sites, cities and inhabitants have developed new needs through the time. The work will demonstrate examples within European context and will make recommendations in monitoring and classification of industrial heritage to prevent undo able losses.
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Evaluation criteria of industrial heritage - practical application
Zelik, Radovan ; Hrabec, Josef (referee) ; Králová, Eva (referee) ; Staňková, Eva (referee) ; Zemánková, Helena (advisor)
The protection of monuments in Slovakia is mostly concentrated on „classical“ examples of cultural heritage (castles, historical city centers). It is not paying much attention to industrial buildings, which are important documents of national development in European context from the era of industrialization. These buildings are often also on the edge of public interest, due to their brownfield character, what places then into the great risk. Because many of these buildings are in private hands, it is often complicated to define the protection policy. It is in the interest of healthy development of society to protect cultural heritage as part of its own identity. The thesis is monitoring approaches to protection of monuments in Slovakia, as well as in global context and offers alternative approaches in terms of protection of industrial heritage.
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Plasma cleaning of corroded plumb objects
Bubnová, Kateřina ; Grossmannová, Hana (referee) ; Krčma, František (advisor)
This bachelor thesis deals with the application of low-pressure hydrogen plasma to lead corrosion products. There are many historical objects and these objects require careful removal of corrosion layers. Therefore, it is necessary to optimize the treatment process in order not to destroy real historical artefacts in the future. This work is focused on lead, which has not been explored by this method yet. Model samples with corrosion were prepared for comparison and these samples corrode in vapors of concentrated acetic acid and formic acid. There were three working temperatures for plasma chemical treatment because of the low lead melting point and the atomic heating. Argon-hydrogen plasma and hydrogen plasma was applied to 12 corroded samples during the experiment. Process progress was monitored by optical emission spectrometry and surface analysis was performed by SEM, XRD and EDX analysis. The results of these analyzes showed that the most appropriate temperature for plasma chemical treatment was 130 ° C. Based on the obtained results many suggesstions and ideas were obtained for the future research like using of pulse mode and gas composition.
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Sequences forming G-quadruplexes in the amyloid beta precursor human gene and its homologues
Stránská, Anna ; Šedrlová, Zuzana (referee) ; Brázda, Václav (advisor)
The APP gene encodes the transmembrane protein amyloid beta precursor, which is expressed in many cell types, including neurons. Its functions have not yet been fully described, but it is clear that it is being cleaved before being exported to the extracellular space. It is degraded by various degradation pathways also undergoes homodimerization, which can produce particles with protective neuronal function as well as fragments that are toxic and cause nerve cell death. The formation of harmful amyloid beta plaques and their accumulation among neurons in the brain is closely linked to the onset and progression of Alzheimer's disease, a neurodegenerative brain disease manifested by death and loss of neurons, which leads to dementia, i.e. loss of cognitive functions. There is currently a lot of research that deals with the links between neurodegenerative diseases and the occurrence of G-quadruplexes in genes that are involved in disease manifestations. G-quadruplexes are non-canonical DNA and RNA nucleic acid secondary structures that arise in guanine-rich regions. They are important mainly in terms of their connection with biological processes such as the regulation of gene expression in genes and mainly in oncogenes because they occur in important regions of the gene such as the promoter. It is possible to stabilize them with small molecules, and it is this ability that is used in research into the therapeutic treatment of various diseases. A bioinformatics analysis of both the human gene and 346 other gene homologs was performed to determine the importance of G-quadruplexes localization and conservation in the human APP gene. For this purpose, the G4Hunter program was used, which provided information about the found sequences with the potential to form a G-quadruplex, such as their location or G4Hunter score. In vitro analysis was performed using thioflavin T reagent, which tested the ability of the found sequences to form G-quadruplexes under physiological conditions. The results confirmed the presence and evolutionary importance of G-quadruplexes found in the APP gene of Homo sapiens and their ability to assemble into quadruplex structures in the presence of salts such as sodium and potassium.
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The ruins and the possibilities of their conservation
Pyreňová, Eliška ; Vyšvařil, Martin (referee) ; Rovnaníková, Pavla (advisor)
This bachelor´s thesis deals with a question of conservation of castle ruins. The theoretical part discusses generally building materials used in their construction, sort of material´s degradation and corrosion of materials, possibilities of ruin´s conservation by using suitable building materials, and processes in realization of historical property restoration. Work focuses on a history and conteporary condition of two historical buildings, the castle Cimburk in Czech republic and the castle Lietava in Slovakia. As a part of my work was collection and subsequent analysis of samples of historical mortars of these castle. Resulting response curves differential thermal analysis, RTG diffraction analysis and their mutual comparison.
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Osud hradů a zámků po roce 1989 v okresech Tábor, Český Krumlov a Prachatice
DŘEVOVÁ, Lenka
The thesis will deal with the fate of castles and chateaus in three districts of the South Bohemian Region, one inland and two border districts located in the area of the former Sudetenland. In the theoretical part of the thesis, three basic aspects influencing their historical development will be discussed - the role of conservation, the number of visitors and the owners of the castles and chateaux. In the research part I will create a database of still existing castles and palaces in selected districts. This will be followed by a presentation of the five selected objects, consisting of a brief history and a description of the historical development of the castle or chateau in the 20th century, which had a significant impact on its post-war status. The aim of the thesis is to map the fate of castles and chateaux in the three districts under study, as well as to provide a detailed description of the five selected historic buildings.
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