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Family and school life of children with Obsessive-compulsive disorder
Pokorná, Kateřina ; Lorenzová, Jitka (advisor) ; Hnilica, Karel (referee)
This thesis deals with the complications that brings obsessive-compulsive disorder (OCD) school-age children in the family and school life. It consists of two parts - theoretical and practical. The theoretical part is divided into the seven chapters and is drawn from the knowledge of professional literature and Internet sources. This section consists of basic information about OCD, the etiology, diagnosis, treatment options. The last three chapters deal with the consequences of obsessive-compulsive disorder and problems that OCD brings to family and school life. The practical part is an empirical investigation dealing with the main objective of the work, which is based on an analysis of complications that brings obsessive-compulsive disorder of school-age children in the family and school life. Survey results was achieved through open, axial and selective coding, which allowed delineation create grounded theory. It was found that OCD manifests in childhood and brings negative consequences not only for family but also for the school life of the child, especially in the form of disturbed domestic atmosphere and the inability to concentrate on teaching.
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Home care of oncological patiens
Pokorná, Kateřina ; Haškovcová, Helena (advisor) ; Holmerová, Iva (referee)
This thesis is about home care of oncological patiens. The thesis is divided into two parts. First part deals with all aspects of home palliative care. The second part presents results of the action research. The questionnaire investigate with how are the oncological patiens and their family informed about home care.
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Pre-clinical model of acute promyelocytic leukemia: Study of the anti-leukemic effect induced by ATRA and DNA vaccination
Pokorná, Kateřina
DOCTORAL THESIS 2012 POKORNA Abstract We have used a well characterized transplantable transgenic mouse model which mimics human acute promyelocytic leukemia (APL), both in its biological characteristics and its response to conventional therapeutic drugs. The aim of our study was to better characterize the efficacy of the combined treatment and to determine molecular markers of clinical outcome. We established a minimal residual disease monitoring based on the high sensitivity of detection of PML-RAR transcripts by polymerase chain reaction (PCR) technology in APL mice. We showed that oncogene-specific PCR-based assays allow, like in patients, the diagnosis, follow-up and prediction of disease evolution. Furthermore, PCR assay was used to assess various tissues and organs for the presence of PML-RAR-positive cells in minimal residual disease free long-term survivors. As expected, majority of mice had no measurable tissue level of PML-RAR demonstrating the efficacy of immunotherapy. However, tracking the oncogene-positive cells reveals for the first time that extramedullary PML-RAR-positive cell reservoirs such as the brain may persist and be involved in the leukemia relapse. We aimed at investigating the immune responses involved in the anti-leukemic effect of the combined immutherapy. To evaluate the...
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The impact of the process changes on the calculation of the chosen company
POKORNÁ, Kateřina
The purpose of this thesis is to analyze ongoing processes in the selected small and medium-sized enterprise Pokorny - Sítě s.r.o. Further, to find the bottlenecks, suggest how to improve them and to determine whether these improvements were reflected in the calculations of the products which are made in the company Pokorny - Sítě s.r.o. The thesis is divided into two parts: theoretical and practical. The theoretical part is divided into several chapters that describe the basic parts like the process, the process management, the process maps, the process management improvement, the reengineering and others. This section helps us to understand and to describe the basic concepts and definitions related to the process control. The practical part is based on analysis of business processes, observations and interviews with the employees and management of the company Pokorny - Sítě s.r.o and identify the bottlenecks which impede the ongoing processes to continue. After the bottlenecks were identified, the changes of the production process were proposed and applied to the production process of the company. The new layout of the production process led to the elimination of the bottlenecks and the reduction of the production time and also impoved the efficiency and continuity of ongoing production process. Subsequently, new calculation formula was propounded. The new calculation formula provides more information per product (costs - fixed and variable, margin, profit per product etc). The result of the applied changes in the production process is the streamlining production, reduced costs and increased company's profit per product.
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Evaluation of the Communication on Social Networks of Selected Titles of the Company Economia
Pokorná, Kateřina ; Černá, Jitka (advisor) ; Ischia, Michal (referee)
The content of the thesis is a description of social media and social networks and the following analysis of communication on social networks for titles Hospodářské noviny, Respekt and Ekonom which belong to company called Economia. The main goal of this thesis is to analyze and to compare the communication on social networks of each title and come up with a recommendation for the titles. The secondary goal of this thesis is to map the situation of social networks and propose the procedure for companies which want to analyze the communication on social networks or compare their communication with competitors. In the practical part, there will be used Socialbakers Analytics tool for analyzing the communication, as well as Google Analytics and Facebook Insights. There will be also used a questionnaire survey among fans of titles and public.
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The Efficiency of Chondroitin suphate, Glucosamine and other supplements of joint nutrition to the articular and musculoskeletal system in the world literature.
Pokorná, Kateřina ; Vilikus, Zdeněk (advisor) ; Tuka, Vladimír (referee)
Title The efficiency of Chondroitin sulphate, Glucosamine and other supplements of joint nutrition to the articular and musculoskeletal system in the world literature The aim of the work The aim of thesis is to assess the efficacy of glucosamine, chondroitin sulphate, hyaluronic acid and diacerein to the structure of joints with joint disease, especially osteoarthritis, according to world literature. Methodology Bachelor thesis is conceived as review of the world literature on the topic. The main method of the work was compilation meta-analysis based on an analysis of numerous quality publications and world scientific literature focused on the topic of bachelor thesis. Electronic databases EBSCO and PubMed and Internet search engine Google Scholar were used as resources for search. Results It found several high-quality studies concerning the influence of drugs of SYSADOA group on the structure of joints. Generally, drugs of this group may have some influence not only to symptoms accompanying osteoarthritis, but also the structure of joint tissues. However, some studies refute this claim. Therefore, it is necessary perform further extensive studies. The correlation between the stage of disease of the patient and the effectiveness of the individual active substances was found. Patients with moderate...
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How active seniors cope with stereotyping
Pokorná, Kateřina ; Šanderová, Jadwiga (advisor) ; Tuček, Milan (referee)
The diploma thesis "How active seniors cope with stereotyping" presents the view of active senior citizens on the issue of ageism in Czech society. Research based on analysis of semi-structured interviews shows that active seniors do not consider inequality as a major problem, mainly because of their life optimism, which helps them overcome the stereotypes. Another important strategy the respondents - active seniors - apply is building/keeping a distance between themselves and the rest of the senior population, upon which they look the same way as the rest of Czech society does. The idea that they themselves do not match the prejudices, but the other seniors do, reinforces the stereotypical view of older people and also presents the active seniors as exceptional. The veneration of an active lifestyle in old age does not seem to be a direct effect of active aging trend, as all respondents had been very active throughout their whole life. Although active seniors present themselves as open to society, they prefer to spend their free time with other (active) people of their own age. Despite the rhetoric of assertiveness they are often passive, when confronted with discrimination, and try to sidestep an anticipated unpleasant situation.
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The Community Trademark - grounds for refusal
Pokorná, Kateřina ; Dobřichovský, Tomáš (advisor) ; Růžička, Michal (referee)
The purpose of this rigorous thesis is to explore the absolute and relative grounds for refusal of registration of the Community trademark. The paper deals with the basic principles of the Community trademark including the description of the registration process. The paper further describes each of the absolute and relative grounds for refusal of application and analyses the decisions of the Court of Justice of the European Union concerning the individual grounds.
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Family and school life of children with Obsessive-compulsive disorder
Pokorná, Kateřina ; Lorenzová, Jitka (advisor) ; Hnilica, Karel (referee)
This thesis deals with the complications that brings obsessive-compulsive disorder (OCD) school-age children in the family and school life. It consists of two parts - theoretical and practical. The theoretical part is divided into the seven chapters and is drawn from the knowledge of professional literature and Internet sources. This section consists of basic information about OCD, the etiology, diagnosis, treatment options. The last three chapters deal with the consequences of obsessive-compulsive disorder and problems that OCD brings to family and school life. The practical part is an empirical investigation dealing with the main objective of the work, which is based on an analysis of complications that brings obsessive-compulsive disorder of school-age children in the family and school life. Survey results was achieved through open, axial and selective coding, which allowed delineation create grounded theory. It was found that OCD manifests in childhood and brings negative consequences not only for family but also for the school life of the child, especially in the form of disturbed domestic atmosphere and the inability to concentrate on teaching.
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