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Molecular simulations in structure analysis of intercalates
Veteška, Marek ; Pospíšil, Miroslav (advisor) ; Beneš, Ludvík (referee)
The samples of hydrotalcite intercalated with pyrenetetrasulphonate acid were obtained. Their structure cannot be precisely determined by the analysis of X-ray data. The amount of water in the interlayer space and the structure of the samples differed considerably in dependence on humidity. Convenient procedures and minimization strategy were established on the base of X-ray data in the molecular mechanic and the molecular dynamic simulations. A procedure for using of the supramol software was made. This software enables deterministic searching of conformational space. Initial models from supramol were minimized in the Cerius2 software using the Universal force field and then they were eventually optimized by the molecular dynamics. The arrangement of molecules of pyrenetetrasulphonate acid and water was determined in the interlayer space of hydrotalcite for three different samples with different interlayer distances: The sample 1 prepared by RH = 0%: 9.83A; the sample 2 prepared by RH = 84%: 13.63A; the sample 3 prepared RH = 40%-50%: 11.74A a 12.81A. The results of these structures proved a large variability of the arrangement of the molecules in the interlayer space. The sample No. 3 seems to be unstable.
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Reverse parallel configuration manager
Doležal, Petr ; Yaghob, Jakub (advisor) ; Adámek, Jiří (referee)
Existing tools for build and configuration management of software projects often suffer from various drawbacks, the typical problems include, for example, a complicated notation of a project's configuration or difficulties with the portability of a configuration description between various platforms. This work analyses the advantages and disadvantages of the approaches used by existing implementations and it proposes the solution that is based on merging the well-established and interesting ideas of various existing solutions. An important part of the work is the implementation of a fully functional program according to the proposed design, which allows to test the solution in practice. The goal of the implementation is to avoid the disadvantages of existing similar programs while keeping their advantages.
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The analysis of financial management in selected municipalities
Skořepová, Nikola ; Slaboch, Josef (advisor) ; Čermák, Jiří (referee)
The main focus of this bachelor thesis is the analysis of the financial economics of Stezery during the years 2010 to 2015. This village is located around 7 km from Hradec Kralove, inside Kralovehradecky region. The aim of this work is to find options on how to make better economics of the village and recommend possible actions. The thesis is divided into two parts, theoretic and practice.
Theoretic part is focused on describing the concept of connecting to the village municipality, the budget of this municipality, authorities, incomes and costs. Briefly described are ideas for the village Stezery and propose an analysis of economics for it. The incomes and expenses of the municipal budget during the years 2010 to 2015 are solved in practice part. Except of the analysis of incomes and expenses there are a lot of economic indexes such as liquidity, analytical debt and budget balance, which illustrate the economics of the village.
There is an overall summary and evaluation of the minucupality is economics at the end of my bachelor thesis. According to established results were suggested to the municipality several recommendations.
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On-line learning in real-time environments
Pacovský, Ondřej ; Spier, Emmet (advisor) ; Mrázová, Iveta (referee)
In this work, a novel reinforcement learning algorithm, Stimulus Action Reward Network (SARN), is developed. It is targeted for application in real-time domainswhere the inputs are usually continuous and adaptation must proceed on-line, without separate training periods. Another objective is to minimise the amount of problem-specific teacher(human) input needed for successful application of the algorithm. The SARN architecture combines a connectionist network and scalar reinforcement feedback by employing Hebbian principles. By adapting the network weights, connections are established between stimuli and actions that lead to positive feedback. Since the links between the input stimuli and the actions are formed quite rapidly, it is possible to use a large number of stimuli. This leads to the idea of using recurrent random network (Echo State Network) as a pre-processing layer. Prototype implementation is tested in Unreal 2004 game environment. The comparison with Q-learning shows that on the time scale of tens of seconds to minutes, SARN typically achieves better performance. When coupled with an Echo State Network, SARN requires a uniquely low amount of problem-specific information supplied by the teacher. These features make SARN useful for domains such as autonomous robot control and game AI.
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Economic Diplomacy of China in Africa
Dus, Jakub ; Stuchlíková, Zuzana (advisor) ; Vlčková, Jana (referee)
This study is about economic diplomacy of China in Africa. It describes development of China-Africa relations, their current form and examines, whether less democratic countries trade more with China than the democratic ones. The study is divided into four chapters. The first one defines economic diplomacy theoretically. The second one focuses on China-Africa relationship from its history up to establishing of Forum on China-Africa Cooperation. It also describes motives of China-Africa cooperation, stressing China's energy dependance. The third chapter describes development of China-Africa trade, Chinese foreign direct investments and development aid and pros and cons of China's presence in Africa. The last chapter examines relationship between level of democracy in african countries and their trade with China.
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Business Plan for Establishment of Travel Agency
Nenička, Dominik ; Dvořák, Jiří (advisor) ; Musil, Martin (referee)
The subject of this thesis is a Business plan. This business plan describes the idea of establishing a new travel agency which would offer school trips to London. The theoretical part of the thesis describes basic terms at first. Then it summarises the theoretical knowledge of creating a business plan. The practical part of the thesis includes the research and producing of the busi-ness plan for an imaginary travel agency, EnHol, s. r. o. In the end the whole thesis and business plan are evaluated.
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Business plan for Air transport company
Sobotová, Kateřina ; Fuchs, Jan (advisor) ; Cimler, Petr (referee)
The main point of this graduate work is to investigate objectively how the current situation on czech trade looks like. Based on this evaluate if it is good idea to establish new air transport company for private charter flights. For this purpose, was made market research and good imitation of real new company formation. All obtained data will be compare and evaluate for final decision. For analysis was used a website showing summary of one hudred the biggest companies in the Czech Republic and websites of czech airliners which makes competitive environment actually.
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Dynamický Balanced Scorecard v učící se organizaci
Leciánová, Gabriela ; Uhrová, Inka (advisor) ; Dedouchová, Marcela (referee) ; Nováček, Jan (referee) ; Nováček, Jan (referee)
The main goal and intended contribution of the presented doctoral dissertation is to define the most important principles for the usage of the Dynamic Balanced Scorecard (DBSC) as a practical guide for learning organization. The Dynamic Balanced Scorecard is based on the fundamental idea that the conventional (static) Balanced Scorecard (BSC) is not able to encompass the contemporary dynamic environment and hence is not an appropriate tool for any strategic management system. At the beginning of the dissertation, the thesis is dedicated to description of the BSC limitations. Moving further, the thesis establishes a practical guide described in three stages: ? the main principles of DBSC, ? the methodology of implementing DBSC, ? the working model. The model was developed in a real company and is now being used in pilot operation. Furthermore the model contains measurements that help demonstrate the transformation from a traditional organization to a learning organization. I did not find, based on questionnaires collected from 110 companies and my experience in a consulting company, any examples of DBSC being currently used in the Czech Republic. The original hypothesis about non-use of any dynamic model for strategic management system was confirmed in the empirical part of the dissertation.
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Vliv klíštěcích slin na žírné buňky na úrovni signálních drah
HEJDOVÁ, Barbora
Intracellular signalling molecules create the signalling cascades which enable the transfer of the signal to the cell. In this work we have studied the influence of tick saliva on the cytokine production and the activation of signalling pathways in ionomycin stimulated murine mast cells. We found out that tick saliva inhibits production of several cytokines and affects two important signalling pathways in mast cells possibly involved in the regulation of cytokine induction.
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Za rámec běžného plánování podníkání: budování internetového startupu v rychlé ekonomice
Šimek, Vojtěch ; Krause, Josef (advisor) ; Vaněček, Michal (referee)
First part of the thesis compares available approaches on business planning, namely the traditional and newly emerged and proposes a Business Planning Approach Selection Framework that should help (newbie) entrepreneurs with orientation in the chaotic business planning world and choosing an approach suiting their specific needs. Conclusion of the theoretical part is that both the traditional and modern business plans have their role in todays business environment. While the old are great for external presentation and funds securing, the new enable to create more complex process for planning successful business from the original idea to and beyond their launch, building on customer feedback and gradual iterations. The practical part then builds on the theoretical research and aims to check feasibility of an actual business project, a multisided platform mediating sales of automotive financial products. It describes the model refinement and product creation process as well as eventually proves viability and feasibility of the whole business.
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