Národní úložiště šedé literatury Nalezeno 2 záznamů.  Hledání trvalo 0.01 vteřin. 
Vliv klíštěcích slin na žírné buňky na úrovni signálních drah
HEJDOVÁ, Barbora
Intracellular signalling molecules create the signalling cascades which enable the transfer of the signal to the cell. In this work we have studied the influence of tick saliva on the cytokine production and the activation of signalling pathways in ionomycin stimulated murine mast cells. We found out that tick saliva inhibits production of several cytokines and affects two important signalling pathways in mast cells possibly involved in the regulation of cytokine induction.
Ekologie Aktinobakteriálních čeledí \kur{Micrococcaceae, Streptomycetaceae} a \kur{Nocardiaceae} v terestrických ekosystémech
HEJDOVÁ, Barbora
The families Micrococacceae, Nocardiaceae and Streptomycetaceae belong to a large phylum Actinobacteria. This phylum is ecologicaly important and many of its members are mainly found in soil, where they are involved in the carbon cycle and other degradation processes. This capability of degradation of complex bololymers is typical for the genera Arthrobacter and Rhodococcus in the bioremediation process. Other members like Streptomycetes are characterized by the ability to produce antibiotics, which are used in the pharmaceutical industry. In this work, we focuse on metabolism of selected actinobacterilal families, but also on the pathogenicity and to their occurrence in different habitats. We will use these pieces of information to evaluate the abundance and metabolic potential of these families in soil collected from the north-eastern region of Siberia along the Kolyma River (Cherskii, Republic of Sakha, Russia). Sequencing of the samples showed the highest occurrence of Streptomyces and Arthrobacter genera and have also relatively large metabolic potential cellulose and phenolics degradation, mainly in the upper soil layers.

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