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Knowledge transfer on the background of National Innovation System: the case of Czech biotechnology firms
Vinař, Radim ; Perlín, Radim (advisor) ; Tomeš, Jiří (referee)
9 Abstract It has been widely acknowledged that the ability to learn, to apply outcomes of R&D and to innovate are key-factors of contemporary economic competitiveness. These aspects are of increasing importance in conditions of the Czech republic as well. Therefore, ambition of this diploma thesis is to deepen current insufficient knowledge in this field in our country. The thesis describes interactions of knowledge-intensive biotechnology companies with the innovation millieu of the Czech republic by analyzing the process of scientific knowledge transfer. It aims at identification of the ways in which knowledge is transfered in applied R&D and at rating the importance of different sources of knowledge for biotech firms. At the same time it identifies actors and institutions of czech biotechnology sector and their relations. In order to display linkages between different subjects in biotechnology, the concept of National Innovation System is used. Further, the importance of different spatial levels for knowledge transfer is analyzed and major institutional and social barriers for development of biotechnology sector are discussed. The thesis concludes by making a distinction between formal (joint research activities) and non-formal types (spare-time meetings) of knowledge transfer. Universities, research...
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Copmplex conception of health and sustainable developement
Krýslová, Simona ; Rynda, Ivan (advisor) ; Haškovcová, Helena (referee)
My diploma thesis deals with the topic of health and sustainable development. I am working with two topical Euro-American concepts, the socio-ecological model of health as promoted by the WHO (holistic concept of health) and the strategy of sustainable development as I acquainted myself with it during my studies at the School of Humanities of the Charles University. First of all, I analyse both concepts by means of expert sources. I emphasize their characteristic features, compare them and carry out a synthesis. On grounds of that I demonstrate three established hypotheses: 1. the holistic concept of health and the strategy of sustainable development with regard to their historical development are not only complementary but also mutually conditional concepts; 2. the holistic concept of health and the strategy of sustainable development have many common features; 3. the holistic concept of health is a natural and indispensable part of sustainable development. I began to be interested in interconnecting those topics in my diploma thesis in the moment I found out what both these interdisciplinary and systematic concepts have in common. At the same time, the interconnection was the most precarious part of my work. I did not expect to have any particular difficulties with separating individual features from...
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Versatile use of liquid chromatography and mass spectrometry in drug metabolism studies
Suchanová, Bohumila ; Wsól, Vladimír (advisor) ; Solich, Petr (referee) ; Lemr, Karel (referee)
Human organism has always been exposed to a vast array of chemicals encountered in the environment. Chemical revolution has significantly influenced biological evolution of humans leading to serious unpredictable toxicities. In response to continual chemical stress they have developed a variety of enzymes to transform these xenobiotics. Xenobiotics are mostly highly lipophilic and cannot readily be excreted from the body without metabolism to more hydrophilic, water-soluble metabolites. Not only environmental chemicals represent xenobiotics but also drugs, dietary components etc. Biotransformation studies play an important role in the drug discovery and development process. Usually data from drug metabolism is required before a new substance can advance towards the development stages of a new therapeutic agent. Data on metabolism is frequently used to optimize drug candidates, suggest more active compounds or support toxicology studies. The increased flux of new chemical entities into drug discovery has placed an increased need for fast and reliable information on the metabolism of these substances. Liquid chromatography coupled with mass spectrometry can meet demands for rapid drugs and metabolites analysis imposed by modern drug discovery strategies. This dissertation thesis presents an evidence...
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Proposal technology of production scheet-metal part of car body
Sviták, Martin ; Špaček, Jindřich (referee) ; Žák, Ladislav (advisor)
The Master’s Thesis is focused on stamping of sheet metal parts. The analyzed part is a structural part of an automobile body. The part is made of DC04 (cold rolled mild steel) material. The annual pruduction volume is 10.000 pieces. Theoretical background research is a knowledge base for design of tooling that can produce parts which meet quality requirements. There are three technological processes proposed in the Thesis. An economic analysis identifies the optimal technological process for the production volume. The thesis contains a complex analysis that confirmes material formability. Computer simulation verifies the part design, material and technological parameters of the forming process.
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Comparative study of methods of librarians work with school aged children in order to develop reading literacy
Kadučáková, Mária ; Landová, Hana (advisor) ; Drobíková, Barbora (referee)
KADUČÁKOVÁ, Mária. 2016. Comparative study of methods of librarians work with school aged children in order to develop reading literacy. Prague, 106 p. Diploma thesis. Charles University. Faculty of Arts: Department of Information Studies and Librarianship. Supervisor: PhDr. Hana Landová, Ph.D. The diploma thesis is dedicated to the methods of work of children's librarians with younger school age readers in order to develop their reading literacy. The aim of this work is to acquaint with the specifics of younger school age readers, to analyze the librarian in the children's department and to link these two elements to achieve interplay in the development of reading literacy. The thesis can be divided into three main parts, theoretical, analytical and empirical. The first two chapters focus on the theory in the field of reading literacy, specifics of younger schoolchildren, furthermore focuses on the working environment of children's librarians, their competence and skills, particularly in education and basic methods of work with children. The next two chapters have analytical character and they examine reading literacy support abroad. Included is also an analysis and comparison of children reading literacy support in two countries surveyed, the Czech Republic and Slovakia. At the same time, these...
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The Way - A Pilgrimage through the Eyes of an Atheist
Šlemrová, Helena ; Špirk, Ivan (advisor) ; Synecký, Jakub (referee) ; Špirk, Ivan (referee)
Master thesis is a theoretical and practical study of choosen topic. It contains part of text and diary from pilgrimage realizated by my self completet by photograph. There are creative workes designed by children according to suggest which you can find in text part. Subject of theoretic part is a study about religion pilgrimage in past and today. There is comparson with unique Hájek pilgrimage too. In didactic part suggest creative projectes for basic school and university of art. Deal especially with religious and usual thinges in world today. The practical part and today in my graduation thesis I did try to show theoretical and in picture new look on pilgrimage.
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Ingrid Kurz and her Contribution to the Development of
Šindelková, Markéta ; Čeňková, Ivana (advisor) ; Vavroušová, Petra (referee)
The MA thesis Ingrid Kurz and her Contribution to the Development of the Theory of Interpreting is a descriptive theoretical study dealing with the work of the conference and television interpreter, Interpreting Studies scholar and professor of Translation Studies at University of Vienna Ingrid Kurz, born Pinter. This thesis analyses individual stages of her research and looks into the development of her opinions and interests, which can be followed chronologically in her articles, studies and extensive publications. It also informs on teaching and interpreting projects of this researcher and, last but not least, reflects her contribution in the area of interdisciplinary cooperation. The interconnection of psychological and interpreting education inspired her towards the first experiments in the field of simultaneous interpreting. Keywords: Ingrid Kurz, theory of interpreting, interdisciplinary research, cognitive psychology, quality of simultaneous interpreting, stress, the media, audiovisual interpreting, didactics.
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Writing in the Streets - a Comparison of Danish and Czech City Planning
Hubáčková, Barbora ; Špirk, Ivan (advisor) ; Raudenský, Martin (referee)
annotation: Hubáčková B.: Signs in the streets - Comparison of Danish and Czech city design. (Graduation theses) Prague 2006 - Charles University, Faculty of Education, department of art. Signs in the streets - Comparison of Danish and Czech city design is a desk study which is concerned with history and forms of visual communication in public area and its position in the early 21st century. The target of these graduation theses was compare the position and level of visual communication in Denmark and in the Czech Republic. Information and orientation systems are incorrect in both countries but the errors come from different reasons. The big differences were noted at the level of processing of advertising which is at an even higher level in Denmark due to of stability and tradition of craft. keywords: street development, graphic design, visual communication, design, orientation system, advertising, poster, graffiti.
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Family and connected things
Jeřábková, Marie ; Pešková, Jaroslava (advisor) ; Lášek, Jan Blahoslav (referee) ; Semrádová, Ilona (referee)
Family has gone through its own change during the course time and it seems that a complexity of time and a complexity of a situation inside the family das not fully aliowe a creation of a security of home and proximity. A man is disturbed, he/she lapses from ones s own principles nad often even looses meaning. Where a relationship can be terminated any time, a man does not have to make any efforts.. A hope for a melamoipliosis of a man oilers a chance for him to "return to oneself'' and to - from inside - understand a necessity for "nurturing" his or her own partnership with a lasting care - a marriage preceeded by "exclusivity" of a partner's choice. A quality of marriage and a foundation of a family is then found in a Jove lived", despite failures, where "two freedoms" meet, mutually offering their own opportunities and also belief in The Other one with the absolute hope in his or her change a"d his or her lasting discovery. Once a man understands the problem (?) he/she will find that a family and home represent for a child the highest value - the greatest gift inside which a child can grow and to let grow the original human "it", which will enable liim/or her to meet one's own "das Selbst", the wholeness of the world and of the universe. In the security of home not only a respect for difference can také...
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Jak čelit nejistotě při rozhodování o odstranění fosforu ve vodohospodářství
Brabec, Jan ; Vojáček, Ondřej (advisor) ; Zajíček, Miroslav (referee)
Implementation of EU Water Framework Directive has led to an increased demand for cost-benefit analysis in water management. The directive introduces a good status, which is required on all water bodies by 2027. Excessive phosphorus inflows are one of the main reasons for not meeting the criteria in the Czech Republic. If achieving of the good status is not cost-proportionate, exemption can be applied. Many different methodologies were created across different states, including Czech official methodology by Slavíková et al. (2015). However, this methodology does not deal with uncertainty of measures effectiveness. This thesis describes how to implement the uncertainty into calculations using Bayesian networks. A case study of Stanovice water reservoir demonstrates the approach practically. Results of the Bayesian network show, that selected measures with available data eliminate desired amount of phosphorus in 70% of all cases. This reduction is most likely sufficient, because it holds for the upper estimate of required abatement (60 to 200 kg). Based on comparison of benefits and costs, it seems net benefits are generated by implementing suggested measures. Therefore, policy recommendation is to implement the selected measures.
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