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Providing brief interventions related to the use of tobacco and nicotine products for patients in outpatient and inpatient healthcare facilities
Hubáčková, Jana ; Rolová, Gabriela (advisor) ; Votavová, Aneta (referee)
Background The using of tobacco and nicotine products causes nicotine addiction. Cigarette smoking increases the risk of cardiovascular disease and lung disease. It is involved in the development of metabolic diseases and diseases of the gastrointestinal and urogenital tract. Brief interventions in the area of smoking are carried out to reduce the risks associated with the use of tobacco products and provide decision support in quitting. Healthcare staff in the hospital setting should provide brief interventions targeting the use of tobacco and nicotine products. Currently, the topic of providing brief interventions in hospital settings is minimally researched. Objectives The objective of the research was to find out whether the medical staff carry out short interventions and to map the range of brief interventions associated with the use of tobacco products provided by the medical staff in a university hospital in Prague. Methods The research was carried out on the basis of a quantitative questionnaire survey conducted among the medical staff (doctor, general nurse and other medical staff - paramedic, nurse, practical nurse) of 3 clinics in the university hospital in Prague. The data were subsequently processed in MS Excel and evaluated using descriptive statistical methods. Results Based on a...
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Prevalence of kratom use among 8th and 9th-grade students in primary schools in the Nymburk district - a questionnaire survey
Škabradová, Barbora ; Jandáč, Tomáš (advisor) ; Votavová, Aneta (referee)
Background: Mitragyna Speciosa - a plant, more commonly known as kratom, that has a history and tradition in Southeast Asia for centuries. In recent decades, it has been gaining popularity worldwide. In addition to its benefits, which include energizing, pain and stress relief, and reducing opiate withdrawal symptoms, kratom use carries health risks along with the development of addiction. In the Czech Republic, kratom is not yet legislated, its use is not regulated and everyone, including children, has access to it. Aims: The aim of this study was to map the lifetime prevalence among 8th and 9th graders in the Nymburk district and patterns of use, their awareness in terms of effects, risks and availability, sources of information about kratom and attitudes towards it. Methods: The data were collected using a paper questionnaire in four primary schools in the Nymburk district. The schools were selected by random sampling. 287 pupils participated in the survey. Results: 17.8% of pupils had experience with kratom. Boys reported experience more often than girls. More than half of the respondents with experience have used kratom at most twice, got it for free from a friend and tried it out of curiosity. The most well-known desirable effects in pupils' minds were feeling calm and relaxed and increased...
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Methodology for assessing the effect of sublethal doses of pesticides on solitary bees employing the OMICs approach
Erban, Tomáš ; Shcherbachenko, Elena ; Šlachta, Martin ; Cudlín, Pavel ; Chalupníková, Julie ; Halešová, Taťána ; Tomešová, Daniela ; Václavíková, Marta ; Votavová, Alena
Pollinators are potentially exposed to a number of pesticides in the environment. The most important group of hazardous substances comes from the category of plant protection products (PPPs), which are applied not only by farmers but also by small gardeners. Each PPP including the active substance and formulation undergoes a very detailed and thorough evaluation, which is in the European Union (EU) based on Regulation (EC) No 1107/2009 of the European Parliament and of the Council. Although the negative effects of PPPs on the environment and non-target organisms are minimized with proper use, we cannot rule out possible hidden effects, especially those of a sublethal nature. Modern analytical approaches, such as the application of high-throughput methods, help to identify hidden side effects. This methodology is focused on the evaluation of the effect of sublethal doses of pesticides on solitary bees employing the OMICs approach. In the risk assessment of pesticides, the honey bee has long been preferred as a model species of pollinator, while solitary bees stay in the background. The methodology contains innovative aspects for experiments, such as a modified isolator, preparation of plants for exposure, the timing of the experiment, monitoring of active substance distribution or proteomic analysis of solitary bees to identify hidden effects of the test substance or its formulation. In this methodology, the model of the solitary bee, red mason bee (Osmia bicornis), is considered. However, the methodology is also applicable to other, especially related species of solitary bees. The methodology can be used in areas of state administration, private laboratories and research activities in the assessment of environmental risks of pesticides on solitary bees. The methodological procedure can confirm or even eliminate environmental risks when registering new products or reevaluating existing products. This methodology therefore has the potential for use in testing new substances intended for plant protection before their registration. In an exemplary embodiment, the effect of acetamiprid in a Careo sticks formulation was tested. The distribution of acetamiprid in the soil substrate and the plant was evaluated. The hazardous metabolite acetamiprid IM-2-1 was identified in plant tissues. However, proteomic analysis indicated a very low risk of acetamiprid for O. bicornis. This result is in agreement with the fact that acetamiprid has been assessed by EFSA to be a low risk for bees and is registered in the EU until 28 February 2033.
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Screening for impairment and design of a rehabilitation program for executive function in substance abusers from the perspective of an addictionologist
Votavová, Aneta ; Šťastná, Lenka (advisor) ; Miovský, Michal (referee)
Background: The entire research is based on the hypothesis that due to regular and long-term abuse of addictive psychotropic substances, the risk of damage to executive and cognitive functions in a given user increases. If a deficit develops, very often there is a decrease in the quality of life of the individual. The addictologist should be able to notice a deficit in his patients and, if confirmed, also intervene in the right way. Aim: The aim of the research is to create a proposal for two cognitive rehabilitation programs that could be implemented in clinical work with addictological patients. If an executive or cognitive deficit is detected in a patient, the selected programs should be able to provide high- quality and effective rehabilitation. In this way, each of the programs could bring a higher quality of life in selected patients. Another aim of the diploma thesis is to test the selected research set for damage to executive functions. The research set is divided into four groups. Each group is characterized by an abuse of a selected addictive substance or group of addictive substances. Methods: Each participant in the research set was tested through a test battery. The test battery was composed of several parts. These included frontal Assessment Battery, Pathway Test (version A, version...
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Measures to support populations of solitary bees in agroecosystems
Šlachta, Martin ; Erban, T. ; Votavová, A. ; Cudlín, Ondřej ; Cudlín, Pavel ; Halešová, T.
Solitary bees participate in the pollination of crops. According to our field\nsurvey, this involves 88 species of solitary bees in spring, mainly mining bees\n(Andrenidae) and sweat bees (Halictidae) nesting in the soil. The species\nnesting above soil were present less due to the lack of nesting opportunities\nand generally summer nesting activity. Among them, mason bees (Osmia sp.),\nnesting in spring, are used abroad for the pollination of fruit trees. The aim of\nthis methodology is to provide farmers with instructions for the use of mason\nbees for pollination of orchards by means of artificial nesting sites. We propose\na convenient construction of nesting sites and the methodology for rearing the\nEuropean orchard bee, Osmia cornuta (Latreille, 1805), which is, due to its earlyspring nesting activity, a suitable substitute for the currently used buff-tailed\nbumblebee. Breeding can be supplemented by the red mason bee, O. bicornis\n(Linnaeus, 1758), with later nesting activity. The book contains also suggested\nmeasures to support solitary bees in the landscape and new research data on\nthe diversity of solitary bees and pollen preferences of mason bees.
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Methodology for assessing the effect of sublethal doses of pesticides on solitary bees\nemploying the OMICs approach
Erban, T. ; Shcherbachenko, E. ; Šlachta, Martin ; Cudlín, Pavel ; Chalupníková, J. ; Halešová, T. ; Tomešová, D. ; Václavíková, M. ; Votavová, A.
Pollinators are potentially exposed to a number of pesticides in the environment. The\nmost important group of hazardous substances comes from the category of plant protection\nproducts (PPPs), which are applied not only by farmers but also by small gardeners. Each PPP\nincluding the active substance and formulation undergoes a very detailed and thorough evaluation,\nwhich is in the European Union (EU) based on Regulation (EC) No 1107/2009 of the European\nParliament and of the Council. Although the negative effects of PPPs on the environment and nontarget organisms are minimized with proper use, we cannot rule out possible hidden effects,\nespecially those of a sublethal nature. Modern analytical approaches, such as the application of\nhigh-throughput methods, help to identify hidden side effects. This methodology is focused on the\nevaluation of the effect of sublethal doses of pesticides on solitary bees employing the OMICs\napproach. In the risk assessment of pesticides, the honey bee has long been preferred as a model\nspecies of pollinator, while solitary bees stay in the background. The methodology contains\ninnovative aspects for experiments, such as a modified isolator, preparation of plants for exposure,\nthe timing of the experiment, monitoring of active substance distribution or proteomic analysis of\nsolitary bees to identify hidden effects of the test substance or its formulation. In this methodology,\nthe model of the solitary bee, red mason bee (Osmia bicornis), is considered. However, the\nmethodology is also applicable to other, especially related species of solitary bees. The\nmethodology can be used in areas of state administration, private laboratories and research\nactivities in the assessment of environmental risks of pesticides on solitary bees. The\nmethodological procedure can confirm or even eliminate environmental risks when registering new\nproducts or reevaluating existing products. This methodology therefore has the potential for use in\ntesting new substances intended for plant protection before their registration. In an exemplary\nembodiment, the effect of acetamiprid in a Careo sticks formulation was tested. The distribution of\nacetamiprid in the soil substrate and the plant was evaluated. The hazardous metabolite\nacetamiprid IM-2-1 was identified in plant tissues. However, proteomic analysis indicated a very\nlow risk of acetamiprid for O. bicornis. This result is in agreement with the fact that acetamiprid\nhas been assessed by EFSA to be a low risk for bees and is registered in the EU until 28 February\n2033.
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Screening of executive function impairment in alcohol users from the point of view of addictologist
Votavová, Aneta ; Šťastná, Lenka (advisor) ; Miovský, Michal (referee)
Background: Long-term regular alcohol consumption poses a real risk of impairing executive functions. An addictologist, as a specialist health care professional, should be able to create and screen executive functions from his or her professional position through a test battery. Based on the performed screening, subsequently evaluate the state of these functions in the given patients. Aim: Creating the design of the test battery of executive, or cognitive, functions that an adjunct scientist has in his remit. Validation of this test battery and its sensitivity to picking up any potential deficit in executive and cognitive function. Perform anamnestic description of selected adjunct patients, dependent on alcohol. Evaluating the effectiveness of the test battery created and recommending it if appropriate by a future research investigation. Methods: The data was obtained through a created test battery. The test battery was made up of International Physical Activity Questionnaire, Beck Depression Inventory, Beck Anxiety Inventory, Trail Making Test, Addenbrooke's Cognitive Examination, Barthel Index, The Lawton Instrumental Activities of Daily Living Scale and Dysexecutive Questionnare. The entire aunt battery was supplemented with an anamnestic sheet, helping to make up the patient's image. The...
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Democratic deficit of the European Union
Votavová, Andrea ; Rovná, Lenka (advisor) ; Šlosarčík, Ivo (referee)
The diploma thesis analyses the democratic deficit of the European Union. Each state which enters the European Union has to transfer a part of its sovereignty to supranational institutions. These institutions than adopt legal acts binding for all member states. The paper deals with the separation of powers in the process of adopting legal acts on the European level. The legislative power is represented mainly by the directly elected European Parliament. The diploma thesis defines the term "democratic deficit" as a weakening of the legislative power to the benefit of strengthening of the executive power on the European level and then deals with its origin and development with the emphasis on the increasing competences of the European Parliament. The last part focuses on an engagement of the European Parliament itself in an attempt of removing the democratic deficit, especially in the period after the adoption of the treaty of Nice and the entering of the Lisbon treaty into force.
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