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The regulation of financial markets - contemporary legal aspects
Špaček, Martin ; Kohajda, Michael (advisor) ; Kotáb, Petr (referee)
The subject of this thesis is the evaluation of certain legal aspects of financial markets regulation related especially to dealing activities. Important role plays the context of contemporary period struggling with the consequences of recent financial crisis with the emphasis put on EU (resp. national) regulation. The first part is in general devoted to the meaning of existent regulation itself. Related legislation and institutional layout are subsequently brought closer in context of national and esp. EU environment. Certain point of interest deserves even (american) the most comprehensive financial markets reform ever. The key part of this thesis devotes to public law aspects instantly influencing dealing and trading activities on financial markets and their contrast to reality. The first theme describes categorization of clients entering on financial markets and duties put on subjects involved (counterparties), who conclude ind. deals with them. Then follow rating agencies, who have been influencing daily routine on financial markets for years and whose evaluation activities imminently influence the row of processes present on financial markets - starting from calculation of capital adequacy requirements until settlement of credit derivatives trades. Capital adequacy is put in context with...
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New biological markers in lymphoproliferative diseases
Špaček, Martin ; Mandys, Václav (advisor) ; Smolej, Lukáš (referee) ; Lysák, Daniel (referee)
New biological markers in lymphoproliferative diseases Summary The prognosis of patients with lymphoid neoplasms is extremely variable. Reliable prognostic markers could allow the identification of patient subsets that may benefit from alternate approaches. Epstein-Barr virus (EBV) is associated with approximately one third of Hodgkin lymphoma (HL) cases. EBV-DNA is often present in the plasma and whole blood of EBV-associated HL patients. However, the significance of EBV-DNA monitoring is debated. In a cohort of 165 adult HL patients EBV-DNA viral load was prospectively monitored. Our results suggest that assessment of plasma EBV-DNA viral load might be of value for estimation of prognosis and follow-up of patients with EBV-positive HL. The role of the TP53 gene's R72P polymorphism in NHL has been analyzed in several studies but it has not been studied in HL. We have evaluated the role of R72P in 340 NHL and 298 HL patients. Our results support the evidence that R72P is not a prognostic factor in Caucasian NHL patients, and they indicate its irrelevance for HL development or prognosis. In a study of 73 patients with chronic lymphocytic leukemia we have assessed IgVH mutational status, presence of mutation in TP53 gene and expression of CD38 and ZAP-70. Overall concordance between ZAP-70 expression and IgVH...
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Spirituality in Seriously Ill and Dying Patients
Špaček, Martin ; Lachman, Jan (advisor) ; Keřkovský, Pavel (referee)
This thesis focuses on spirituality particularly in relation to dying and death. It aims to provide an introduction to spirituality for health care professionals - especially physicians - as well as to discuss possible ways of addressing spiritual concerns in complex care of patients. The secularization of modern society and technological advance in medicine have extensively marginalized death and dying. However, hospice movement and palliative care reintroduced a new model of "good death" and revived interest and recognition of spirituality of seriously ill and dying patients. Despite multiple official recommendations including World Health Organization statements spirituality has a low profile both in our society and health care system, spiritual issues are generally not considered in medical education or in training of allied professions. Spirituality - as well as religion - is a complex phenomenon and may be discovered and expressed in wide variety of ways, depending on cultural and religious traditions. Medical staff should be able to identify and address spiritual issues of importance to their patients, not only in the end-of-life issues but also during the course of treatment. Powered by TCPDF (www.tcpdf.org)
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Management spa
Špaček, Martin ; Čapov, Martin (referee) ; Němeček, Petr (advisor)
This thesis deals with analysis of internal and external spa environment which is used for definition of business strategies. These strategies should be implemented by company for increase its ability to compete. The thesis also describes potentialities and benefits of using e-marketing.
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Questions around the introduction of euro in the Czech Republic
Janna, Martin ; Vopátek, Jiří (advisor) ; Špaček, Martin (referee)
The goal of the thesis is to propose an opinion regarding the accession to the eurozone supported by the analysis of the related benefits and constraints in connection with the current economic and political situation. Allowing to get an idea of what the benefits and downsides of euro adoption would be for them, the gathering of information and arguments suitable for entrepreneurs, managers and citizens is the sought outcome of the work. The issue was analysed both quantitatively and qualitatively with the help of the SWOT analysis, optimum currency area theory and analysis of macroeconomic indicators. To achieve a more comprehensive understanding, also political programmes of the political parties represented in the Chamber of Deputies of the Czech Parliament were analysed. The contribution of the thesis lies in providing a comprehensive insight into issues regarding the euro while assessing the current situation and indicating the closest possible date for euro adoption.
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Strategic management in Ekvita, s.r.o.
Doležal, Ondřej ; Svobodová, Ivana (advisor) ; Špaček, Martin (referee)
The diploma deals with the strategic management in small and medium-sized companies. The strategic management is applied to a specific company operating in the field of mechanical engineering. The main goal of the diploma is to propose strategic variants focused mainly on the company's' development and resulting from the external and internal analyses. The results from both analyses are further used for the SWOT analysis which summarizes the strengths and weaknesses of the company influenced from the "outside" as opportunities and threats. SWOT analysis led to the definition of two strategic variants. First one is focused on the development of a new product; second one is more about searching for new opportunities on the market and marketing. After evaluating both proposals and considering dis/advantages only one has been recommended for the realization -- the second proposal.
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The analysis of the causes of decline in selected football clubs
Pánková, Barbora ; Novotný, Jiří (advisor) ; Špaček, Martin (referee)
The aim of this work is to identify and describe the causes of the problems of football clubs Glasgow Rangers FC and Portsmouth FC, which entered the financial crisis. This thesis aims to answer the question, what constitutes the greatest danger for the club and which factors play the most important role in the financial decline of football clubs. The theoretical part of the work provides the methodological basis for the practical part, where the individual clubs are analyzed in case studies. The last chapter deals with the destiny of football villages in the Czech Republic and Germany.
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Financial analysis of the company Karlovarská Korunní s.r.o.
Horváth, Jiří ; Špička, Jindřich (advisor) ; Špaček, Martin (referee)
The Bachelor thesis is devoted to financial analysis of the company Karlovarská Korunní s.r.o. The goal of the thesis is to evaluate the overall financial position of the company between the years 2008 to 2012 from the perspective of a minority shareholder. The company's annual reports were used as the main source of information. All of the applied methods are described in detail in the theoretical part of the thesis. The practical part then then applies these methods on Karlovarská Korunní s.r.o in order to evaluate the company's financial health. The methods of financial analysis used in the thesis include vertical and horizontal analysis, application of financial ratios, and evaluation of economical value added, evaluation of working capital, bankruptcy and creditworthiness models or comparison with competitors. The end part of the thesis summarizes the retrieved information.
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Financial analysis of Vinné sklepy Valtice a.s.
Gruberová, Milena ; Špička, Jindřich (advisor) ; Špaček, Martin (referee)
The bachelor thesis analyzes financial situation of company Vinné sklepy Valtice from 2007 to 2012. The thesis consists of two parts -- theoretical and practical. The theoretical part includes methods used in practical section. To analyze the company, we use vertical and horizontal analysis, differential indicators, financial ratios, credibility and bankruptcy models. Final results are compared with the results of competitors in viticulture by the means of different methods. A complete financial situation of the company is summarized in conclusion.
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