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Cost-effectiveness model of universal screening for thyroid disorders in pregnancy for the Czech Republic
Tužil, Jan ; Bartáková, Jana (advisor) ; Brennan Kearns, Pavla (referee) ; Babeľa, Róbert (referee)
Model nákladové efektivity plošného screeningu poruchy funkce štítné žlázy v těhotenství pro Českou republiku Cost-effectiveness model of universal screening for thyroid disorders in pregnancy for the Czech Republic Disertační práce English Abstract Introduction: Subclinical hypothyroidism affects approximately 5% of pregnant women in the Czech Republic and is associated with a number of health risks for both mother and child. The negative effects can be prevented by effective and safe hormone replacement therapy. Although subclinical hypothyroidism can be diagnosed solely by blood tests, only 45% of pregnant women in the Czech Republic are currently tested. Thyroid function screening (thyrotropin; TSH) can be accompanied by thyroid autoimmunity testing (anti-thyroid peroxidase antibodies; anti-TPO) to predict increased risk of postpartum thyroiditis. Aims: The aim is to model the cost-effectiveness, budgetary impact and impact on routine practice of the introduction of universal TSH screening (versus the current state of things) and an addition of the universal anti-TPO screening (versus TSH screening alone). Method: The cost-benefit ratio, budget impact, and impact on routine practice were modelled using a decision tree for implementation of the TSH test and a nested decision tree for the addition of the...
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Library of Reusable Components and Utilities for the Angular 2 Framework
Branderský, Gabriel ; Beran, Vítězslav (referee) ; Herout, Adam (advisor)
Táto práca sa zaoberá vytvorením knižnice znovapoužiteľných komponent a utilít určené na použitie v dátavo-intenzívnych aplikáciach. Jednou typickou komponentou pre také aplikácie je tabuľka, ktorá je považovaná za hlavnú komponentu knižnice. Pre zaistenie vysokej kohezie sú všetky ostatné komponenty a utility sú s nou úzko prepojené. Výsledná sada komponent je použiteľná deklaratívným spôsobom a umožnuje rôzne konfigurácie. Uživateľské rozhranie je tiež prizpôsobené na dátovo-intenzívne aplikácie s rôznymi prvkami.
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Intelligent Fighting Units
Kužela, Martin ; Janeček, Petr (referee) ; Drahanský, Martin (advisor)
The field training of army units includes high financial, material and human resource investments. From this reason, an emphasis on the simulator training of these units arised recently. But the training in simulator needs to have the simulated units as intelligent as a human beings are, so the field training with real human opponents can be successfully replaced with the simulator training. This work deals with the design of fighting unit's intelligent behaviour, that will be applicable in the E-COM simulator environment. Work covers the description of intelligent agents and ways how to achieve their rational and autonomous behaviour. The proposal and the analysis of intelligent fighting unit's implementation and unit's communication with surrounding environment, basic implementation of this proposal and experiments with created implementation are also described in this work.
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Measurement of data network quality parameters
Ripper, David ; Kováč, Dominik (referee) ; Zeman, Václav (advisor)
The aim of this thesis was studying and describing known methods for testing transmission parameters in data networks based on protocol stack TCP/IP. Firstly were individual transmission parameters specified and determined their impact on service quality. Another aim was to carry out a comparison of the different methodologies of measurement of transmission parameters, performed their qualifications on the basis of these findings and methodology for measuring service quality from the user's perspective was proposed. It was a web application where users measured basic transmission parameters, then the users judged videos according to the evaluation scale MOS (Mean Opinion Score) and with the help of these data was analysis, classification connection and impact of connection on MOS evaluation.
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Mathematical Models of Demand
Trzaskaliková, Eva ; Půža, Bedřich (referee) ; Mezník, Ivan (advisor)
The diploma thesis deals with the analyses of demand using standard tools of engineering mathematics. Mathematical models of demand, both single and multi- factor are investigated. Elasticity of demand is applied for decision making in price policy. Problems of optimization of demand reflecting utility and budget constraints are under consideration. Constructions of demand curve and compensated demand curve are presented. The text is accompanied by illustrative examples aiming at methodical aspects of the work
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Visual support of theoretical explanation in MPKT course
Passinger, Jiří ; Koutný, Martin (referee) ; Jeřábek, Jan (advisor)
The bachelor thesis deals with creating animations and using the selected utilities in operating systems GNU/Linux and Windows. This work describes the selection of programs for creating animations, the procedure of animation creation and their resulting form is shown. Further on there are suggested possibilities of use of the animations, their extention and description of theory to the action the animations deal with. Another part is dedicated to utilities for IPv6, DNS and ARP. Real examples of using these utilities the format writing and examples of responses are shown.
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Application of recent methods for synthesis of heat exchanger network
Kunc, Vlastimil ; Kohoutek, Josef (referee) ; Jegla, Zdeněk (advisor)
Master’s thesis deals with the problems of heat exchanger network synthesis and compare the present methods with emphasis on Pinch Design Method and deterministic method. Based on theoretical formulation of deterministic model the computer program for heat exchanger network synthesis was developed in the software Maple environment. Developed software implementation of deterministic method has been applied to several case studies.
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Analýza hospodaření vybraných ekologických farem
Peichlová, Zuzana
The diploma thesis analyzed selected production and reproduction factors in Czech Fleckvieh cattle. The data was obtained from three organic farms and one conventional farm for comparison. The owners wished to remain anonymous. The data was collected from the utility inspection records and zootechnical evidence from the years 2020, 2021, and 2022. From the production indicators, the following factors were monitored: daily yield, number of lactations, fat content (%), protein content (%), somatic cell count (thous./ml), number of born and raised calves, and culling rate (%). From the reproductive indicators, the following factors were monitored: insemination index, insemination interval, service period, intercalving period, and pregnancy after first insemination (%). The findings indicate that the production indicators on organic farms are not the worst, and the conventional farm only has problematic somatic cell counts and numbers of born and raised calves. Reproductive indicators show better values on organic farms, while the conventional farm reports worse indicators.
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