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Synthesis of amides of 3,4-benzotropolone-carboxylic acid
Panýrková, Gabriela ; Machara, Aleš (advisor) ; Rýček, Lukáš (referee)
Tropolone and benzotropolone are both naturally occurring motifes with broad spectrum of bioactivities and interesting properities that are connected to these structures. This bachelor thesis explores preparation of 3,4,6-trihydroxy-5H-benzo[7]annulen-5-one, so called purpurogallin and it's possible preparation by enzyme catalyzed reactions and further synthetic use of these products. The study is mainly focused on synthesis of 3,4-benzotropolon- carboxylic acid, specially it's amides. First part deals with choosing the optimal reaction conditions for formation of these amides. In the next part palladium catalyzed carboxylations were performed on prepared bromoderivate of dehydroxypurpurogallin. Key words tropolones, benzotropolones, dehydroxypurpurogallin-4-carboxylic acid, amides, optimization, enzymatic catalysis, carboxylation
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Marketing Strategies of Czech Football Clubs: Targeting Fans through Match Programs
Grečl, Michal ; Crossan, William Morea (advisor) ; Kaprálková, Michaela (referee)
Title: Marketing Strategies of Czech Football Clubs: Targeting Fans through Match Programs Objectives: The aim of the thesis is to present recommendations to increase the level of fan experience on match day with regard to the objectives of marketing teams in reaching their defined segments of people. The thesis offers a cross- comparison through interviews with high-level marketers of selected first league participants of the highest Czech football competition, complemented by direct observation and data analysis, focusing on the essence and justification of the individual steps implemented by the clubs in the matchday programme in relation to their strategic targeting. Methods: The thesis uses a qualitative research approach with selected professional football clubs in the top Czech football competition, specifically in-depth semi-structured interviews with high-level marketing staff, focusing on their perceptions, experiences and decision-making processes in the field of marketing, together with the essence and justification of the individual steps they implement. The research also includes direct observation of match programmes and analysis of data collected from football clubs and publicly available sources. The thesis then conducts a comparative analysis to compare the differences and...
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Family Trees Making from Archive Records
Haltmar, Adam ; Zbořil, František (referee) ; Rozman, Jaroslav (advisor)
This thesis is about optimalization and increasing precision of already existing program for processing, comparing and linking archive records about people in a way to store them in a graph database while constructing family pedigrees as a side effect. It shows where the algorithm was approached badly and makes better alternatives for lowering the computation time. It also presents new methods for increasing the precision of record linking like name standardization and compares tests with the original program. Result of these changes is accelerating the program by more than 5000 %.
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Process model of the switchgear laboratory
Paloš, Radek ; Bušov, Bohuslav (referee) ; Šimek, David (advisor)
This thesis deals with the issue of process optimization. Especially with two selected methods, Lean six sigma and TRIZ. Both of these methods are briefly described, especially we could find in this thesis chapters about history, options of usage, and description of selected tools for realization. The thesis also deals with the comparison between methods, including their advantages and disadvantages. The next part of the thesis is about process mapping of preparation before testing electrical devices in the UVEE department FEEC laboratory, which is part of BUT. Except process map, there is an analysis of each process, evaluation, and future possible optimization.
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Registration of retinal image data using evolutionary algorithms
Matoušek, Šimon ; Mézl, Martin (referee) ; Odstrčilík, Jan (advisor)
This thesis deals with the registration of retinal images. Firstly, the introductory chapter summarizes the theory related to evolutionary algorithms and their practical application in the form of a literature search, then different approaches of retinal image registration and image transformation are described. At the same time, the anatomy of the eye as a key organ for visual perception is briefly introduced. In the practical part of the thesis, the method of registration of static and then dynamic retinal images is implemented using MATLAB software environment, and finally the results of different approaches are compared.
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Optimizing the line-up of a sports team in a sallary capped league
Sabo, Adam ; Popela, Pavel (referee) ; Hrabec, Pavel (advisor)
This thesis is focused on the optimization of the lineup of a professional sports team operating under a salary cap condition. In the first part of the thesis, the theoretical foundations necessary for a proper understanding of the issue are introduced. Further, mathematical statistics and optimization methods are explained here and used in data analysis and in the creation of the relevant model. Particular emphasis is put on the methods of principal component analysis and linear programming. In the second part of the thesis, the problem of the optimization task, which takes into account the relevant NHL rules of competition and the salary cap together with performance characteristics of players, is formulated. The formulation was used to develop an optimization model that simulates real conditions in the NHL. This section also presents the application of the model based on historical data. Results obtained from calculations using the Python programming language are presented in the form of graphs, tables, and commentaries, showcasing the optimal team lineups, their characteristics, and respective rankings.
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Evolutionary Design of Neural Networks
Kastner, Jan ; Hurta, Martin (referee) ; Sekanina, Lukáš (advisor)
The thesis deals with the implementation of a problem-solving method for the automated design of convolutional neural networks (CNN) architectures. The optimization of two fundamental and often conflicting characteristics, the number of parameters and the quality of CNN classification, is performed using a multi-criteria optimization genetic algorithm (NSGA-II). To encode this problem, the Cartesian genetic programming (CGP) technique is used, which enables the wide range of CNN architectures to be represented, and at the same time, the searched area can be appropriately limited by parameterization. Experiments were performed on the MNIST dataset to understand the effect of population size on the quality of the resulting solution. It is also evident from the results of the experiments that the quality of the architectures found can compete with already established models. This is therefore an alternative approach that does not require human intervention compared to manual design.
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Improvement of turbocharger inlet manifold parameters
Kula, Štěpán ; Vacula, Jiří (referee) ; Novotný, Pavel (advisor)
The bachelor thesis deals with the design of a new elbow geometry to reduce the pressure drop in the inlet suction pipe of a turbocharger compressor. At the beginning of the thesis there is a description of the fluid flow and hydraulics losses that result in pressure loss in the pipe. Next, possible methods by which the shape of the piping can be optimized are described. The last, main section deals with the actual optimization of the elbow using the manual method and the Adaptive Single-Objective method, which succeeded in reducing the pressure losses and improving the outlet flow profile.
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Optimization of the Manual Coil Wrapping Workplace
Válková, Aneta ; Machačová, Simona (referee) ; Videcká, Zdeňka (advisor)
This bachelor's thesis is focused on the optimization of the manual coil winding workplace in the Elektromotory Drásov spin-off plant of the Innomotics company. There are downtimes at the workplace due to excessive walking, which is the result of an inefficient layout of the workplace. In the theoretical part, individual concepts of process management in production are explained together with methods and tools for improving processes. In the analytical part, the company is described in more detail, especially its current state, including the waste that occurs here. In the design part, two proposals for a new workplace layout are created, which are further compared and, with the help of analyses, their savings in production time, excess walking and financial resources are evaluated.
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