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The Maleč farm at the time of F.L. Rieger
Vojáček, Milan ; Čechura, Jaroslav (advisor) ; Hájek, Jan (referee) ; Štaif, Jiří (referee)
František Ladislav Rieger was o ne of the most famous Czech politicians of the second half of the 19th century. He was František Palacky's son-in-law and his successor in the leading of the Czech politics. He and his wife Marie Rieger bought the Maleč farm from Franz Xaver Auersperg in 1862. Rieger had already had experience with management of a farm in Suchdol between 1854 and 1857. The Suchdol farm, much smaller than Maleč, did not bring enough profit. Rieger sold the Suchdol farm and his saw mill in Semily and bought the Maleč domain for 300 000 guldens. It was a big investment and Rieger had to mortgage the farm as well as his wife's house in Prague. By the research I wanted to answer the following general questions: 1. How did the farm in Maleč work? 2. How much ofhis time and effort did F. L. Rieger invest in the management? 3. How much money did he need for his representative life of an important Czech politician? 4. Where and how did he get his money? As far as the theme "Farms in the second half of 19th century" is concerned, analytic studies are very rare in the Czech historiography. Most studies about family farms do not go beyond the middle of the 19th century. The available literature is more general in its focus- about the agriculture, industry, demography, Rieger and his family, or political...
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Biological activity of antioxidant compounds in monocytes THP-1
Hájek, Jan ; Boušová, Iva (advisor) ; Szotáková, Barbora (referee)
Charles University in Prague University Roma Tre Faculty of Pharmacy in Hradec Králové Department of Biology Department of Biochemical Sciences Candidate: Jan Hájek Supervisor: PharmDr. Iva Boušová, Ph.D. Prof. Sandra Incerpi, Prof. Jens Z. Pedersen Title of diploma thesis: Biological activity of antioxidant compounds in monocytes THP-1 Elaboration of this work is based on the experiments carried out in the Laboratory of Physiology at University Roma Tre in Rome, under the supervision of Prof. Sandra Incerpi. The team of this laboratory studies the antioxidants of different structures and evaluates their ability to prevent the production of reactive oxygen species (ROS). These reactive species are essential for many physiological processes, but they can also have deleterious effects and participate in the development of various diseases. In this work, I dealt with a study of antioxidant properties of different polyphenolic compounds (mosloflavone, negletein, 5,6-dihydroxyflavone, baicalein, gallic acid, and compound 1625) in the cell culture of human monocytes THP-1 and also in the in vitro test. Three different methods were used: intracellular ROS determination (dichlorofluorescein assay), cytotoxicity assay, and electron paramagnetic resonance spectroscopy (EPR). Mosloflavone showed scavenging...
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Cooperative as one of the possible tools of the economic concept of Steady-State
Dekastello, Petr ; Hájek, Jan (advisor) ; Vejchodská, Eliška (referee)
The thesis analyzes the theory of Steady-State Economy based on a research of literature as well as principles and starting points for its application in practice. The central question revolves around the viability of the theory. First, however, the thesis focuses on the context, i.e. the background and needs for the emergence of this theory. Thus, the research begins at a time of industrial revolution and the rise of modern economies. In the course of the research, the analysis also points out the phenomenon of cooperatives, which arise in the early days of industrialization, as examined at the start of the work. Later, after a comprehensive introduction of the steady-state economy theory, the thesis returns to cooperatives, as during the research certain parallels in both of the phenomena emerge. Consequently, the conclusion recapitulates and examines whether steady state economy has been proven to be viable, what could support its functioning and whether one of the answers might be cooperatives - considered they have been shown to realize certain assumptions of this economic theory in practice. After a review of criticism of both of the phenomena, a final evaluation and decision may be reached, i.e. the research questions may be answered.
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Web Application for Estate Agency
Hájek, Jan ; Kunc, Michael (referee) ; Grulich, Lukáš (advisor)
This thesis is addressed on making a web application for a real-estate agency. In this application both common users and administrators will be able to access and employ the underlying system with ease. The system will be holding up-to-date list of available realties, as well as managing the presentation. The thesis contains description of the complete developing process, including initial specifications, covering diagramme projecting and the final implementation itself, with XHTML, CSS, PHP, MySQL and JavaScript technologies used.
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Alfred Nobel's dynamite factory in Zámky by Prague during the monarchy and the first Czechoslovak Republic
Jandek, Prokop ; Jakubec, Ivan (advisor) ; Hájek, Jan (referee)
(English) The thesis concerns itself with the functioning of the concern belonging to Alfred Nobel in Bohemia and other parts of Austria-Hungary. Particularly regarding the inception and operation (range of products, position on the market, health and safety) of dynamite factory in Zámky by Prague and the adjacent factory producing artificial fertilizers in nearby Lísek. Other minor topics include the stance of Austrian authorities towards the new industry, characterisation of individuals connected with the facility, relations with the headquarters of the company in Vienna and the fate of this subsidiary in the successor state of Czechoslovakia. The thesis is set into the period 1868-1926 during which the factory belonged to the concern of Alfred Nobel.
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Tax competition: strategic tax rate lowering and expected impact of US 2017 reform on other countries
Hamráková, Júlia ; Janský, Petr (advisor) ; Hájek, Jan (referee)
This thesis deals with an international corporate income tax competition with focus on corporate income tax rate spillovers from the past tax cuts in the USA. The main research question we seek the answer to is: "Do countries follow the USA in the corporate income tax rate setting?" Empirical models were evalu- ated using GMM model for the panel data. Our results confirm the existence of the tax rate spillovers, however, do not prove solid leadership of the USA in the tax rate setting. We found that countries which are geographically closer to the USA and OECD jurisdictions are more likely to follow the USA in the tax rate policy changes. Our research is unique extension to the previous literature dealing with this topic as it uses not only the weighted world corporate income tax rate in the model, but also the corporate income tax rate of the USA and therefore allows us to see the effect of the past tax cuts in the USA for other countries. The results of our work can serve as a lead for examining the impact of the US tax rate cut in 2017. JEL Classification F12, F21, F23, H25 Keywords tax competition, corporate income tax rate, tax spillovers, profit shifting Title Tax competition: strategic tax rate lowering and expected impact of US 2017 reform on other countries Author's e-mail...
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Analysis of Determinants of Carsharing
Špiroch, Jakub ; Chytilová, Julie (advisor) ; Hájek, Jan (referee)
Shared economy is a phenomenon becoming more prevalent in our society. The study explores the case of business-to-consumer (B2C) carsharing. Using a unique cross-sectional data set, which is compiled by aggregating several city- specific demographic and geographic factors, we construct several models which should be explanatory on the characteristics of cities, where car sharing is ac- tive and successful. Firstly, a logistic regression is employed to estimate the impact of predefined factors on the presence of B2C car sharing in a city. We find out that there is significantly positive relationship between the presence of prestigious university and active shared mobility platform. Furthermore, we introduce the OLS regression with log-level functional form to estimate, what determinants affect the quantity of cars in cities. Additionally, we provide explanation on demographic and geographical variables, which have the most defining impact on the prosperity of car-sharing. In conclusion, several sugges- tions on future research and studies based on carsharing success are presented. Keywords car-sharing, shared economy, B2C, Logit, OLS regression Author's e-mail spiroch.jakub@gmail.com Supervisor's e-mail julie.chytilova@cuni.cz
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Biological activity of antioxidant compounds in monocytes THP-1
Hájek, Jan ; Boušová, Iva (advisor) ; Szotáková, Barbora (referee)
Charles University in Prague University Roma Tre Faculty of Pharmacy in Hradec Králové Department of Biology Department of Biochemical Sciences Candidate: Jan Hájek Supervisor: PharmDr. Iva Boušová, Ph.D. Prof. Sandra Incerpi, Prof. Jens Z. Pedersen Title of diploma thesis: Biological activity of antioxidant compounds in monocytes THP-1 Elaboration of this work is based on the experiments carried out in the Laboratory of Physiology at University Roma Tre in Rome, under the supervision of Prof. Sandra Incerpi. The team of this laboratory studies the antioxidants of different structures and evaluates their ability to prevent the production of reactive oxygen species (ROS). These reactive species are essential for many physiological processes, but they can also have deleterious effects and participate in the development of various diseases. In this work, I dealt with a study of antioxidant properties of different polyphenolic compounds (mosloflavone, negletein, 5,6-dihydroxyflavone, baicalein, gallic acid, and compound 1625) in the cell culture of human monocytes THP-1 and also in the in vitro test. Three different methods were used: intracellular ROS determination (dichlorofluorescein assay), cytotoxicity assay, and electron paramagnetic resonance spectroscopy (EPR). Mosloflavone showed scavenging...
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International Spillovers of (Un)Conventional Monetary Policy: The Effect of the ECB and US Fed on Non-Euro EU Countries
Hájek, Jan ; Horváth, Roman
We estimate a global vector autoregression model to examine the effects of euro area and US monetary policy stances, together with the effect of euro area consumer prices, on economic activity and prices in non-euro EU countries using monthly data from 2001-2016. Along with some standard macroeconomic variables, our model contains measures of the shadow monetary policy rate to address the zero lower bound and the implementation of unconventional monetary policy by the European Central Bank and US Federal Reserve. We find that these monetary shocks have the expected qualitative effects but their magnitude differs across countries, with Southeastern EU economies being less affected than their peers in Central Europe. Euro area monetary shocks have greater effects than those that emanate from the US. We also find certain evidence that the effects of unconventional monetary policy measures are weaker than those of conventional measures. The spillovers of euro area price shocks to non-euro EU countries are limited, suggesting that the law of one price materializes slowly.
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