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Alternative Plant Utilization for Obtaining of Significant Nature Substances: Can Weed Find a Utilization?
Wimmer, Zdeněk ; Sajfrtová, Marie ; Sovová, Helena ; Pavlík, Milan ; Svobodová, Hana ; Jurček, Ondřej ; Wimmerová, Martina
Numbers of compounds and their mixtures, which are produced by plants, can be obtained by extracting plant materials by supercritical fluids. Phytosterols and phytoecdysterotds represent an important family of these plant products. They can be used in a synthesis of supramolecular structures with possible importance for targeted effect of drugs or other biological(y active compounds. Target organisms for the compounds investigated are: (a) insects - pests and human food competitors, also important as model system in investigation of convenient application forms of biologically active compounds; (b) cell cultures used during basic pharmacological research. Supramolecular structures may form convenient matrices for practical application of the biologically active compounds. It has already been proved that numbers of medicinal or cultural plants produce important natural compounds. The present question has appeared to be answered, if so far inutile weeds may be turned into important sources of pro-drugs for disease treatments.
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The Model of Financial Compensation for placement of a Deep Geological Repository of Radioactive Waste in the Czech republic in period from 2010 to 2016
Englerová, Anna ; Zeman, Martin (advisor) ; Vebrová, Ludmila (referee)
Author examines a way of allocation of governmental financial resources to municipalities in locations preselected for deep geological repository. She is searching for a way how to add a motivational incentive to the process of allocation of financial resources in order to improve municipalities attitude towards deep geological repository. Hypothesis, examined in this thesis, contains two related questions. It is assumed that (1) amount and structure of financial resources can significantly affect municipalities decision making and also that (2) current mechanism of allocation of compensations is ineffective and does not create sufficient incentives. Currently (end of the year 2016), negotiations between government and municipalities are in crisis despite significant financial compensation from government nuclear account to the municipalities. This thesis have potential to change municipalities negative stance on deep geological repository through motivational model of resource allocation. Theoretical part reviews basic economic background and introduces historical, sociological, technological and economic views of radioactivity and deep geological repository. In practical part author analyzes socio-economic situation, compares evolution of transfers from government to municipalities with their attitude towards deep geological repository in time and shows that current system of resource allocation does not motivate the municipalities to change their stance on deep geological repository. That confirms second part of our hypothesis. Author also proposes a motivational model of resource alllocation. She confirms its viability by comparing it with similar models from other countries, by surveying mayors of concerned municipalities and also by examining experts opinion. Verification of the model confirmed its motivational effect. By that, first assumption of our hypothesis, that structure of resource allocation can significantly affect municipalities decision making, was confirmed.
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Development of interest rates in the mortgage market in the Czech Republic between 2006-2016
Ditrichová, Gabriela ; Strejček, Ivo (advisor) ; Klement, Josef (referee)
This bachelor's thesis is focused on the development of interest rates in the mortgage market in the Czech Republic in the decade between 2006 and 2016. A strong economic growth between 2006 and 2007, which had positive effects in the mortgage loan market, was followed by a deep slump in the form of global financial crisis unleashed by speculations in the real estate market in the U.S. The main aim of the work is based on the development of mortgage interest rates and the significant factors that affect their amount - to verify or disprove the hypothesis that interest rates respond to changes of these factors. The results confirm the hypothesis only in certain areas. The influence of changes of interest rates has been proven in the case of inflation and discount rates by usage of the econometric model. Factors that have not shown a significant direct influence of interest rates may have an indirect influence on their change.
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Sustainable tourism development of Vysocina Region
Veselá, Markéta ; Macháček, Jaroslav (advisor) ; Vondráková, Zuzana (referee)
The diploma thesis deals with the topic of sustainable tourism development at the regional level. This phenomenon is elaborated on the example of Vysocina Region. To evaluate sustainability of its development, the potential of this touristic destination is researched regarding various areas, including key products. These are subjected to comparisons with recommendations of significant tourism organization for the purpose of assessing the sustainability of tourism. The diploma thesis also includes a comparison with other Czech regions experience as a touristic destination. Vysocina Region has favourable initial conditions for its sustainable development, especially regarding supply of key products, which include both environmentally friendly goods and cultural attractiveness contributing to the personal development of individuals and promoting intercultural tolerance. The main issue appears to be the spatial imbalance of its development in the region, caused mainly by the concentration of tourist activities to certain areas and low local initiative in the less attractive areas. The diploma thesis proposes a number of solutions, such as utilization of geocaching and products of gastroturism, supporting the foundation of local destination management organisations, promoting cycling tourism and the foundation of highly visited tourist destinations.
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The Controlling Study
Herda, Tomáš ; Mikovcová, Hana (advisor) ; Herda, Zdeněk (referee)
The main goal of this Diploma´s Thesis is to make a model for calculation of water and sewer rates for the company Vodovody a kanalizace Náchod, a.s. when sticking to the set criteria both from the side of VaK Náchod, a.s. and law regulations. Based on the theoretical part an analysis of customer sensitivity to the price changes using the data for last 20 years follows. Findings from the first two parts are used in risk analysis in next part. The created model calculates the water and sewer rates based on the information from the company accounting system in the way to generate sufficient financial resources to fulfill the renovation plan of infrastructural property plant and equipment and to transfer given amount to the company funds. In addition, the model monitors whether the legal condition of maximal allowable increase of profit per m3 is met. In the customer sensitivity to the price changes part the price elasticity of demand for water and sewer rates is calculated based on the data from 1995 to 2015. The assumption of inelastic demand is confirmed. Risk analysis part is deals with potential risk regarding the demand and prices. Potential impacts for the most significant risk are quantified. The analysis uses knowledge gained in the first two parts. It was confirmed that potential risks are exiting but do not have any significant impact on the going concern of VaK Náchod, a.s. The created model has been already used for the calculation of prices for the year 2017. Customer sensitivity analysis to the price changes and link to the potential risks is an additional information for VaK Náchod, a.s. which validates that nowadays, there are no significant threats which could affect the demand and water and sewer rates significantly.
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Support for Unemployed People Aged Under 30 Years at Entry to the Labor Market
ŠABARTOVÁ, Alžběta
The Bachelor Thesis deals with the problems of unemployment benefits for people at the age up to 30 when entering the employment market. Unemployment is currently one of the serious problems in the world. The reduction in the number of unemployed people is one of the political priorities. The meaning of work as a job is taking an irreplaceable position for the life within our culture. Job loss has a considerable influence on social as well as personal life of an individual. The age is playing a significant role when seeking a job. Especially the time connected with the beginning of the career. School leavers who apply for their first job are concerned. They have no working experience, no practice, and they have so far had no possibility to acquire the basic work habits. A disharmony between zero experience and excessive earnings demands belongs to other root causes of the lack of interest in giving work opportunity to school leavers. Employment Office plays an irreplaceable role for the mediation of job and the consultancy. To solve unemployment within each target group, active and passive labour policies are available. The situation of the specific target group is stimulated especially through single programs and projects. The theoretical part pays attention to the definition and objectification of the unemployment-related terms and the analysis of labour market in Ceske Budejovice. Observations of a number of authors who are dealing with these problems and the related issues are summarized herein. The empirical part is formed by observations from own investigation. Two job-related targets have been set. The first target is to analyse the ideas the young people aged up to thirty, living in the district of Ceske Budejovice, have of their employment. The other target is to analyse the employers´ ideas of giving work to school leavers and young people. In order to fulfil the above targets, two investigative questions have been put: 1: Young peoples´ ideas of earning possibilities are unrealistic. 2: Employers find the European Social Fund helpful in giving work to young people. For the purpose of answering the investigative questions a qualitative research method, namely a case study the study of a few cases was selected. Interviewing was chosen as the most suitable method of data gathering. Initially, ten participants aged up to thirty were interviewed. At the time of interviewing, all of the participants were registered at the Employment Office in Ceske Budejovice and were taking part in a retraining scheme arranged by the Employment Office. When talking with young people I found that their gross commencing salary is expected to amount to approx. 16 200 CZK. The other selective group comprised five employers in Ceske Budejovice. It emerged from the interviews that one of the companies does not utilize the programs and projects announced by the European Social Fund at all. Two of the companies complain about excessive administration. One of the employers must always carefully consider its ability to satisfy the involvement conditions. Some negative feelings also appeared about the frequent changing the blank forms, a low number of announced projects for a particular business branch. The programs being related to deepening knowledge and staff training were most appreciated. The results of the Thesis will give the Employment Office a feedback on the utilization of the European Social Fund by employers and will help in adjusting the conditions for further projects being prepared.
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Film induced tourism
Čepková, Petra ; Abrhám, Josef (advisor) ; Kalábová, Markéta (referee)
The master thesis deals with new phenomenon in tourism film induced tourism. The main objective of the master thesis is to characterize film induced tourism which could be used as a tool to increase the attendance of the destination where the film was shot. Next main objective of the thesis is evaluation of film induced tourism in Europe, more precisely in Great Britain and Northern Ireland where the film induced tourism is at relatively advanced level. The master thesis is divided into the eight main chapters. The first part briefly defines term tourism, its importance and tips related to the place of realization. In the second chapter there is described management of destination, following with marketing direction in the fourth chapter. In the fifth part, there is definition of film-induced tourism, related history, supply, the opportunities of marketing promotion and typology of the film induced tourist. Next parts of thesis show significance and efficiency of film induced tourism, film induced tourism in Czech Republic and in the Europe where the main attention was focused on Great Britain and Northern Ireland. The last chapter refers to own research where the potential of film induced tourism was investigated by using quantitative and qualitative methods from respondents which were based in Czech Republic.
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Discussion on US sanctions against Cuba at the U.N. General Assembly
Šplíchalová, Eva ; Trávníčková, Zuzana (advisor) ; Machoň, Miloslav (referee)
The United States imposed the longest lasting sanction regime on Cuba in 1960 as a result of strained relations in recent years. Each US administration modified form of the sanctions regime, depending on the attitude toward the Cuban issue. General Assembly, the highest authority of the UN, adopts not legally binding but politically significant resolutions. Resolution condemning US sanctions regime has been adopted annually since 1992. Discussion on changes of the sanction regime in the General Assembly is a sign of reflection on current events and unrigid process of resolutions adoption. The main purpose is to determine whether the changes of the sanction regime were mentioned in the discussions on the adoption of the resolutions. The result of the analysis shows the reflection of the events in the speeches of ambassadors. The amount of mentioned events in speeches depends whether they were positive or negative step toward easing the embargo, and also how important the event was.
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Forms of advertising on social networks and consumer protection
Žďárský, Jiří ; Vavrečka, Jan (advisor) ; Štěpánek, Petr (referee)
The theme of this thesis are forms of advertising on social networks and consumer protection. The main informational source is above all research of specialized literature, articles, online or other sources in connection with author's own observations and analysis of the respective legislation and ultimately the comparison with author's gained professional experience. The result of this work is a comprehensive overview and introduction to the law of social networks and advertising, demonstration of the importance and significance of this topic and finally evaluation of the effectiveness of legislation that protects consumers in the environment of social networks.
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Modelling, parameter estimation, optimisation and control of transport and reaction processes in bioreactors.
ŠTUMBAUER, Václav
With the significant potential of microalgae as a major biofuel source of the future, a considerable scientific attention is attracted towards the field of biotechnology and bioprocess engineering. Nevertheless the current photobioreactor (PBR) design methods are still too empirical. With this work I would like to promote the idea of designing a production system, such as a PBR, completely \emph{in silico}, thus allowing for the in silico optimization and optimal control determination. The thesis deals with the PBR modeling and simulation. It addresses two crucial issues in the current state-of-the-art PBR modeling. The first issue relevant to the deficiency of the currently available models - the incorrect or insufficient treatment of either the transport process modeling, the reaction modeling or the coupling between these two models. A correct treatment of both the transport and the reaction phenomena is proposed in the thesis - in the form of a unified modeling framework consisting of three interconnected parts - (i) the state system, (ii) the fluid-dynamic model and (iii) optimal control determination. The proposed model structure allows prediction of the PBR performance with respect to the modelled PBR size, geometry, operating conditions or a particular microalgae strain. The proposed unified modeling approach is applied to the case of the Couette-Taylor photobioreactor (CTBR) where it is used for the optimal control solution. The PBR represents a complex multiscale problem and especially in the case of the production scale systems, the associated computational costs are paramount. This is the second crucial issue addressed in the thesis. With respect to the computational complexity, the fluid dynamics simulation is the most costly part of the PBR simulation. To model the fluid flow with the classical CFD (Computational Fluid Dynamics) methods inside a production scale PBR leads to an enormous grid size. This usually requires a parallel implementation of the solver but in the parallelization of the classical methods lies another relevant issue - that of the amount of data the individual nodes must interchange with each other. The thesis addresses the performance relevant issues by proposing and evaluation alternative approaches to the fluid flow simulation. These approaches are more suitable to the parallel implementation than the classical methods because of their rather local character in comparison to the classical methods - namely the Lattice Boltzmann Method (LBM) for fluid flow, which is the primary focus of the thesis in this regard and alternatively also the discrete random walk based method (DRW). As the outcome of the thesis I have developed and validated a new Lagrangian general modeling approach to the transport and reaction processes in PBR - a framework based on the Lattice Boltzmann method (LBM) and the model of the Photosynthetic Factory (PSF) that models correctly the transport and reaction processes and their coupling. Further I have implemented a software prototype based on the proposed modeling approach and validated this prototype on the case of the Coutte-Taylor PBR. I have also demonstrated that the modeling approach has a significant potential from the computational costs point of view by implementing and validating the software prototype on the parallel architecture of CUDA (Compute Unified Device Architecture). The current parallel implementation is approximately 20 times faster than the unparallized one and decreases thus significantly the iteration cycle of the PBR design process.
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