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Multiple Sclerosis: Corticoid and Biological Therapy, Importance of Pedagogy in Rehabilitation
Rosová, Anna ; Ehler, Edvard (advisor) ; Pavlasová, Lenka (referee)
The submitted thesis deals with the theme of a neurodegenerative autoimmune disease, the sclerosis multiplex. Although this serious disease has become an object of intensive research in recent decades and there is an inexhaustible quantity of literature available, we haven't yet fully identified the causes of this disease as well as we haven't found such kind of effective treatment that would lead to the permanent recovery of patients. I focused my interest on two main spheres: first, the description and comparison of practices in terms of pharmacotherapy giving priority to its benefits to patients, second, the view of another important but not always appreciated part of therapy, physiotherapy or rehabilitation; the main point is studying of processes and actions from the pedagogical point of view.
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The analysis of pharmacotherapy by patients suffering with DM in Greece I
Kalaitzidis, Georgios ; Vlček, Jiří (advisor) ; Doseděl, Martin (referee)
The analysis of pharmacotherapy by patients suffering with DM in Greece I Author: Georgios Kalaitzidis Tutor: Professor RNDr.Jiri Vlcek,CSc. Department of Social and Clinical Pharmacy, Charles University in Prague, Faculty of Pharmacy in Hradec Kralove. Introduction: The diabetes in developed countries concerns 11% of people over 70 years and is the cause of 3% of total deaths in general population. Aim: The aim of the study was to assess the Pharmacotherapy of Diabetes mellitus type II in a pharmacy of a small town of Greece, Veria. Methods: It is retrospective cross-sectional study, which was conducted in a pharmacy in a small town of Greece, Veria. The study population consists of 60 patients with known Type II diabetes Melitus. The data collection was performed by a self-reported questionnaire, which was created and developed by the researcher and filled by the respondents. Results: The mean age of the sample was 56.5±17.5 years. Most of them were females (n=40). Most of the patients knew their fasting glucose level (93.3%,n=56).Of the patients who knew their fasting glucose level, 36 (64.3%) patients had high fasting glucose level and 20 (35.7%) had physiological fasting glucose level. From all the patients(n=60), some of them visited their physician every 6 months (n=24), and every 3 months...
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Recent Findings on the Pharmacotherapy of Methamphetamine Dependence: Potentially Suitable Substances for Methamphetamine Substitution
Oktábec, Zbyněk ; Gabrhelík, Roman (advisor) ; Minařík, Jakub (referee)
Charles University in Prague First Faculty of Medicine Study programme: Specialization in Health Care Branch of Study: Addictology PharmDr. Zbyněk Oktábec, Ph.D. et Ph.D. Recent Findings on the Pharmacotherapy of Methamphetamine Dependence: Potentially Suitable Substances for Methamphetamine Substitution Bachelor's Thesis Advisor: Mgr. Roman Gabrhelík, Ph.D. Prague, 2014 Abstract Methamphetamine has long been a lead drug of abuse among problem drug users on the Czech drug scene. At the moment, there is no worldwide effective pharmacological treatment of addiction on the methamphetamine/amphetamine-like substances. There have been found substances, with the greater or lesser success, from different ATC groups as well as some new substances, which some patients/clients could profit from. Nevertheless we still fail to find a widely effective pharmacotherapy of methamphetamine dependence, which would be efficacious and broadly applicable, i.e. as the substances in the treatment of opioid dependence. This work aims to present current information on substitution and/or craving reduction therapy in the treatment of methamphetamine dependence. This paper has the character of a research/review work and uses up-to-date data, not only in published articles and in the primary literature, but in ongoing clinical trials...
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Analysis of the effect of pharmacotherapy on the risk of a fall I.
Šturcová, Klára ; Malý, Josef (advisor) ; Doseděl, Martin (referee)
Analysis of the Effect of Pharmacotherapy on the Risk of a Fall I. Author: Klára Šturcová1 Tutor: Josef Malý1 1 Department of Social and Clinical Pharmacy, Faculty of Pharmacy in Hradec Králové, Charles University in Pague Introduction: Falls of hospitalized patients are one of the most common problems in health institutions. In terms of prevention of falls it is necessary to analyze all the factors that might have contributed to the emergence of a fall and subsequently minimize these risk factors. Objectives: The aim of the thesis was to analyze the possible drugs and other causes of falls of patients hospitalized in a certain rehabilitation institution. Methods: The data were collected from 21 March to 31 July 2014 in an institution providing rehabilitation care. The evaluated group consisted of patients who fell during the hospitalization in this period. The data about the fall, personal and drug anamnesis were transferred to an electronic form and subsequently evaluated by means of the frequency analysis, converted into graphs and tables and discussed. Results: 67 patients experienced 79 falls. Women experienced 53 % of falls; men experienced 47 % of falls. 87 % of the patients fell once, 9 % of the patients fell twice, 4 % of the patients fell three times. 58 % of all falls were experienced by...
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Analysis of Pharmacotherapy by patients with diagnosis of COPD
Kartali Kaouni, Marilena ; Vlček, Jiří (advisor) ; Matoulková, Petra (referee)
Title: Analysis of Pharmacotherapy by patients with diagnosis of COPD Student: Marilena Kartali-Kaouni Tutor: Prof. RNDr. Jiri Vlcek, CSc Department of Social and Clinical Pharmacy, Charles University in Prague, Faculty of Pharmacy in Hradec Kralove Background: " Chronic Obstructive Pulmonary Disease (COPD) is characterized by airflow limitation that is not fully reversible. The airflow limitation is usually both progressive and associated with an abnormal inflammatory response of the lungs to noxious particles or gases". Tobacco smoking is the major risk factor in the development of COPD. COPD is a leading cause of morbidity and mortality worldwide. Aim: 1st from the current literature to understand the nature of COPD and obtain information about the aetiopathogenesis of the disease, diagnosis options and summarize the current view of strategies for achieving the goals of treatment. 2nd in a pilot study to analyze drug therapy in COPD patients visiting a pharmacy in Greece. Methods: 56 prescriptions with the diagnosis of COPD were collected during a period of 8 months from a Greek pharmacy. Information from the prescriptions with regard to COPD medications prescribed (active substances, trade names, strength, dosage scheme, pack size), patients characteristics (age and gender) and prescribing...
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Analysis of Pharmacotherapy by patients with diagnosis of arterial hypertension
Kontou, Vasiliki ; Vlček, Jiří (advisor) ; Macek, Karel (referee)
Title: Analysis of Pharmacotherapy by patients with diagnosis of arterial hypertension Student: Vasiliki Kontou Tutor: Prof. RNDr. Jiri Vlcek, CSs Department of Social and Clinical Pharmacy, Charles University of Prague, Faculty of Pharmacy in Hradec Kralove Introduction: Arterial Hypertension (AH) is characterized by elevated blood pressure, which often leads to increased morbidity and mortality. AH divided into primary and secondary. Aim: In the theoretical part the aim is to analyse the etiopathogenesis, methods of diagnosis and the treatment strategies of arterial hypertension in the recent literature. In the experimental part the aim is to analyse the provisions of the above diagnosis of arterial hypertension. Method: During a six month period were collected 58 prescriptions with the diagnosis of arterial hypertension from a pharmacy that provided pharmaceutical care in the Greek village, Mytikas. Only one prescription for one patient was analysed. In the prescriptions were collected data on drugs, patients and physicians. Results: The pilot study included 58 prescriptions. Most patients were elderly, over 65 years old and 30% were in age 71 - 80 years. General practitioners prescribed 65% of the medical prescriptions. Most frequently prescribed ARBs with hydrochlorothiazide drugs (27%) and...
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Public Opinion on Methods of Treatment Used at Psychiatric Wards
FILLEROVÁ, Markéta
The thesis deals with up-to-date subject of medical treatment of mental disorders. The work is divided into a theoretical and a practical part. The theoretical part involves explanation of terms such as mental health, mental disorder and also includes classification of mental disorders. There are chapters devoted to mental illness as a social problem, to stigmatization and to the legal issue of people affected with mental illness in the thesis. History of psychiatric treatment and its development are briefly mentioned here and also some important methods used to treat the mentally ill at present. The empirical part is devoted to a quantitative research by means of a questionnaire inquiry. The main objective of the survey was to find out, what is the public opinion on methods of medical treatment applied at psychiatric wards. In this part the obtained data are analyzed and the hypotheses are checked. Evaluation of most of the questions is demonstrated graphically. The conclusion of the thesis involves my opinion on this issue and summary of the research results.
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