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HIL test stand for universal electronic control units
Zouhar, Štěpán ; Musil, Filip (referee) ; Brablc, Martin (advisor)
This diploma thesis is focused on testing of Electronic Control Units, especially functional testing in which hardware and software is verified and also Model in the Loop, Software in the Loop, Processor in the Loop and Hardware in the Loop testing methods. Within practical part of this thesis testing stand for functional test of the ECU was developed and manufactured. It is connected to PC via Input/Output card, testing is controlled by MATLAB script. Whole process of testing is automated from initial upload of testing firmware to tested ECU over all phases of test up to bootloader flashing. Hardware in the Loop test was also created, in which ECU works as controller and DC motor is simulated in real time with PC in MATLAB environment.
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Functional HIL testing of an electronic control unit
Štramberský, Jan ; Appel, Martin (referee) ; Brablc, Martin (advisor)
This thesis deals with the functional HIL testing of a universal electronic control unit. The control unit is graphically programmed in an application in which it is possible to create state machines with pre-programmed functions. Within the scope of this work, a HIL test of the unit has been created. Signals are exchanged between the unit and PC using an input/output card. The PC runs the HIL test script in Matlab. This test verifies the firmware of the unit by checking the expected behaviour of the functions and the conditions of the transitions.
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Physiotherapy in scoliosis after the surgery
Kačírková, Hana ; Šafářová, Marcela (advisor) ; Rampová, Michaela (referee)
The aim of the bachelor thesis is to present information regarding the surgical treatment of scoliosis and care for the operated patient. The options of the operation, its indications, contraindications, risks and goals are presented. The thesis describes the care of the patient preoperatively, perioperatively and postoperatively, and the procedures used and recommended measures are presented. The effect of scoliosis on the patient and the changes after surgery are mentioned. The assumption is that physiotherapy has a positive effect on the outcome of the surgical intervention. Part of the practical part is a case report of a patient with adolescent idiopathic scoliosis after surgery by the posterior approach fusion technique. This patient regularly attended physiotherapy and exercised intensively. As part of the case report, a kinesiological analysis was performed supplemented by functional tests from DNS, dynamic tests, examination of breathing stereotype and measurement of chest flexibility. The examination was carried out twice four months apart. The results were compared with each other with the assumption that continuous rehabilitation before and after surgery will bring improvement in the monitored tests. This assumption was confirmed.
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Phenotypic and functional characterization of leukocytes in patients with immune system dysregulation
Fejtková, Martina ; Kanderová, Veronika (advisor) ; Vlková, Marcela (referee) ; Balounová, Jana (referee)
Inborn errors of immunity (IEI) are a heterogenic group of diseases of the immune system causing dysregulations of both innate and adaptive immunity. New altered immune-related genes are discovered every year, nowadays reaching over 400. (Tangye et al., 2020) Here three new autoinflammatory disorders of IEI patients are described. Toll-like receptors (TLR) 7 and 8 are endosomal receptors in the innate immune response against external pathogens and endogenous autoantigens. A dysregulation in TLR7 and TLR8 in mice causes autoimmunity and inflammation, however, in humans, the immunopathology of TLR8 and TLR7 remains unclear. We identified a novel X-linked c.1715G>T mutation in TLR8 that leads to autoimmune haemolytic anaemia and autoinflammation in male twins caused by dysregulation in TLR8 and TLR7 response especially in myeloid cells (low TLR8 protein expression, cross-reactivity of TLR8 for TLR7 ligands and enhanced TLR7 response). Hematopoietic cell kinase (HCK) belongs to the Src family of kinases and is involved in myeloid cell migration, adhesion and degranulation. Kinase activity in the immune response must be strictly regulated. In HCK, this regulation is based on C-terminal inhibitory tyrosine, which when phosphorylated, HCK kinase activity is switched off. We identified a heterozygous...
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Functional HIL testing of an electronic control unit
Štramberský, Jan ; Appel, Martin (referee) ; Brablc, Martin (advisor)
This thesis deals with the functional HIL testing of a universal electronic control unit. The control unit is graphically programmed in an application in which it is possible to create state machines with pre-programmed functions. Within the scope of this work, a HIL test of the unit has been created. Signals are exchanged between the unit and PC using an input/output card. The PC runs the HIL test script in Matlab. This test verifies the firmware of the unit by checking the expected behaviour of the functions and the conditions of the transitions.
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Complex therapy after surgery impingement syndrome omae
Váchová, Kateřina ; Němeček, Ondřej (advisor) ; Molnár, Petr (referee)
In my work I deal with the processing of case reports of three patients who underwent arthroscopic acromioplasty for the diagnosis of impingement syndrome of the shoulder joint, but each of them was physiotherapy led other way. The work consists of two main parts. The theoretical part includes kinesiology and biomechanics of the shoulder joint, including a description humeroscapularis rhythm and dynamic stabilization. I also deal with the diagnosis and defining impingement syndrome. The next section describes the various methods of complex therapy that can be used for a given problem. The practical part includes processing kinesiology examination, during therapy, and evaluates the effect of treatment with each of the patients. The shoulder joint is the most flexible joint of the human body, which is related to its instability and frequent vulnerability. In NsP Česká Lípa, where I conducted the examination was conducted in 2012, 54 arthroscopic decompression subakromialis type operations in 2013 and this was done in the period from January to end of March already performed 15 operations of this type. This number shows how often a problem is impingement syndrome. The main aim of this study is to compare which approach is beneficial for the patient and how surgery followed by a suitably chosen...
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Reliability of DNS tests in cunical practise
Stýblová, Jaroslava ; Kobesová, Alena (advisor) ; Demeková, Júlia (referee)
Introduction: Functional testing which is used in rehabilitation is mainly based on aspection and palpation. It is a subjective examination of a patient and you cannot find out specific physical quantities with this method. If you want to use functional tests in clinical practise it is necessary to determine the reliability of the tests. Aim: To determine the inter-rater reliability for the DNS tests and to create a detailed descriptive statistics and a new evaluation sheet. Materials and methods: There were six experienced evaluators who are trained for the DNS method. We have worked with a mixed group of patients. There were patients with health problems as well as patients without any difficulties (n = 10 women, average age - 34, 5, n = 4 men, average age - 35, 2). We used percentage agreement, Fleiss's kappa coefficients (κ) and P-value. Results: The research of DNS tests reliability is innovative. Evaluators of DNS tests usually agree with each other. In some cases there is a problem with using Fleiss's kappa coefficients (κ) because of the position of relative frequencies. In most tests we found out that the inter-rater reliability is good (κ ≥ 0.80), substantial (0.60 ≤ κ < 0.80) and moderate (0.40 ≤ κ < 0.60). Conclusion: The evaluation of one character in a case of one patient by three...
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HIL test stand for universal electronic control units
Zouhar, Štěpán ; Musil, Filip (referee) ; Brablc, Martin (advisor)
This diploma thesis is focused on testing of Electronic Control Units, especially functional testing in which hardware and software is verified and also Model in the Loop, Software in the Loop, Processor in the Loop and Hardware in the Loop testing methods. Within practical part of this thesis testing stand for functional test of the ECU was developed and manufactured. It is connected to PC via Input/Output card, testing is controlled by MATLAB script. Whole process of testing is automated from initial upload of testing firmware to tested ECU over all phases of test up to bootloader flashing. Hardware in the Loop test was also created, in which ECU works as controller and DC motor is simulated in real time with PC in MATLAB environment.
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