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Work integration options in people with multiple sclerosis: influence of symptoms and other comorbidities
Ulmanová, Alena ; Novotná, Klára (advisor) ; Rodová, Zuzana (referee)
BACHELOR THESIS ABSTRACT Author: Alena Ulmanová Supervisor: Mgr. Klára Novotná Ph.D. Consultant: Mgr. Eliška Rotbartová Title: Work integration options in people with multiple sclerosis: influence of symptoms and other comorbidities Abstract: This theoretical-practical bachelor thesis focuses on the impact of multiple sclerosis symptoms and other comorbidities on the employment of people who are dealing with this diagnosis. The thesis aims to find out what are the main difficulties that limit the ability to work of people with multiple sclerosis, using a questionnaire of work difficulties called Multiple Sclerosis Work Difficulties Questionnaire (MSWDQ-23). The importance of this aim is based primarily on the fact that the disease mainly affects young adults in productive age, for whom employment tends to be an essential part of life and the difficulties associated with reduced work capacity can negatively affect their financial and social situation, but also their general physical condition. The theoretical part of the thesis summarizes the knowledge on the given issue using the current foreign and Czech literature. In the practical part, quantitative research based on a questionnaire survey is used. A standardize questionnaire called MSWDQ- 23 is used, which comprehensively assesses the work difficulties...
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Interdisciplinary cooperation in planning care for clients with multiple sclerosis in residential respite service
Linhartová, Petra ; Vrzáček, Petr (advisor) ; Mertl, Jiří (referee)
The diploma thesis deals with the effectiveness of interdisciplinary cooperation by setting up processes focused on communication and information sharing in a multidisciplinary team. It is based on theoretical starting points mainly in connection with a systemic approach to the client. The principle of case management, individual cooperation with the client and the consulting paradigm of social work were applied here. The aim of the work is to identify possible forms of effective interdisciplinary cooperation in the selected facility, using the example of which it presents the elements affecting the quality of outputs of care planning for clients with multiple sclerosis in the conditions of a specific residential respite service. In the theoretical part of the thesis, a unique organization in the Czech Republic, which has been involved in the care of people in a long term, especially in the advanced stage of the disease and which includes a residential respite service, is presented. The mentioned respite service strives to improve the quality of care for clients by setting up effective interdisciplinary cooperation using the Human Centered Design (HCD) method. Through a case study describes the process of introducing change and setting up cooperation processes in a specific multidisciplinary team...
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Cognitive rehabilitation of people with multiple sclerosis
Bílková, Tereza ; Novotná, Klára (advisor) ; Krivošíková, Mária (referee)
BACHELOR THESIS ABSTRACT Name, Surname: Tereza Bílková Supervisor: Mgr. Klára Novotná, Ph.D. Consultant: Mgr. Eliška Rotbartová Title: Cognitive rehabilitation of people with multiple sclerosis Abstract: This bachelor thesis focuses on the topic of cognitive rehabilitation in patients with multiple sclerosis, which takes place in a home environment using the computer program HAPPYneuron. Multiple sclerosis is classified as an autoimmune disease, during which the cells of our central nervous system are damaged. The aim of this bachelor's thesis is to test whether cognitive rehabilitation of 16 weeks, conducted through the computer program HAPPYneuron, has a positive impact on spatial orientation, short-term memory, attention and speech in MS patients. In the theoretical part of the bachelor thesis I describe the actual issue of multiple sclerosis, including the clinical picture and types of multiple sclerosis. I then go on to describe in more detail the most affected domains of cognitive function, their examination and the possibilities of cognitive rehabilitation. Last but not least, I describe cognitive rehabilitation using computer programs, with a more detailed description of the HAPPYneuron program. In the practical part, three patients were first examined by a clinical neuropsychologist. Based on this,...
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Multiple sclerosis - clinical and paraclinical markers for monitoring disease activity and factors influencing its course
Šťastná, Dominika ; Horáková, Dana (advisor) ; Libertínová, Jana (referee) ; Taláb, Radomír (referee)
Multiple sclerosis (MS) is a chronic neurological disease that, without treatment, leads over years to decades to severe disability in most patients. We cannot cure the disease, but there is growing evidence that early initiation of anti-inflammatory therapy and management of associated comorbidities has a major impact on its course. Patient registries have an irreplaceable contribution to evaluating factors influencing the MS course and the monitoring of therapeutic agents in real clinical practice. First, this thesis evaluated therapy management trends between 2013 and 2021 based on data from the Czech National MS Registry (ReMuS). Subsequently, the paper responds to the onset of the covid-19 pandemic through registry data and addresses this issue in the context of MS. The proportion of patients in ReMuS treated with high-efficacy disease-modifying therapies (HE-DMT) increased from 16.2% to 37.1% between 2013 and 2021, and the proportion of treatment-naive patients initiating HE-DMT increased from 2.1% to 18.5%. Regarding covid-19 infection, we determined that higher body mass index, older age, recent high-dose glucocorticoid treatment, and anti-CD20 therapy were independent variables associated with pneumonia based on data from 958 MS patients with a history of covid-19. Further, we analyzed...
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Eye-Tracking Control of an Adjustable Bed
Kopeček, Martin ; Kremláček, Jan (advisor) ; Čapek, Lukáš (referee) ; Komzák, Martin (referee)
The origin of this work was based on the need to control an electric positioning bed by patients with no or significantly reduced upper limb motor skills. The key point and objective of the dissertation study was to develop non-contact alternatives to manual controls and to verify that the eye-tracking technique is usable and offers patients a new level of increased self-sufficiency. The thesis is organized into three related parts with experiments conducted at the detached departments and in the laboratory. After an introductory section covering the stages of development and current progressive trends in eye movement tracking, an experimental study of the applicability of bed control with the role of alternating head and leg position changes using on-screen graphical controls is described. This stage was conducted using a virtual bed. In a group of 17 patients with diagnoses of a pentaplegia, tetraplegia, high paraplegia, myopathy, and spinal muscular atrophy, the overall time to solve the task was 67.1 s (median) with a large interindividual variability with interquartile range from 56.7 s to 92.9 s. The solution efficiency (100 % matched to optimal performance) was 45.5 (34.9; 62.0) %. Within each group patients achieved different results for both studied parameters. When evaluating the features of the...
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Physiotherapy during Covid - 19 pandemic within patients with sclerosis multiplex
Knapová, Ivana ; Novotná, Klára (advisor) ; Havlová, Martina (referee)
Name, surname: Ivana Knapová Supervisor: Mgr. Klára Novotná, Ph.D. Title: Physiotherapy during COVID-19 pandemic within patients with sclerosis multiplex Abstract: This work focuses on the possibilities of physiotherapeutic intervention in patients with multiple sclerosis who experience persistent symptoms after recovering from COVID-19 infection. The main aspects of therapeutic intervention include physical therapy and respiratory physiotherapy. The theoretical part of the work introduces the issue of post-COVID syndrome and delves into its terminology, pathogenesis, diagnosis, prevalence of clinical symptoms, and therapeutic possibilities from both general and physiotherapeutic perspectives. Another part is dedicated to the characterization of multiple sclerosis itself, providing a detailed description of the basic characteristics of this disease. In the concluding section of the theoretical part, topics such as pulmonary rehabilitation, respiratory physiotherapy, and physical therapy are thoroughly discussed. The main objective of this work is to provide an overview of the benefits of respiratory physiotherapy and physical therapy for patients with multiple sclerosis who experience post-COVID syndrome symptoms. As part of this objective, a brochure containing exercises suitable for self-therapy...
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Pain in patients with multiple sclerosis
Paulů, Kateřina ; Novotná, Klára (advisor) ; Grosserová, Barbora (referee)
The bachelor thesis deals with the topic of pain in patients with multiple sclerosis. The aim of the thesis is to map the prevalence of pain among patients with multiple sclerosis, its localization, time course, triggering factors, type, character, intensity and some other aspects pain through a shortened Czech form of the standardized questionnaire of McGill University. The thesis consists of theoretical and practical part. The theoretical part deals with the issue of pain in general, but also focuses on the individual types of pain that are characteristic of multiple sclerosis. The practical part relies on data collection by means of a questionnaire survey that focuses on mapping the prevalence of pain, its location, haracter, duration, intensity and other possible related factors. To collect data, I used a shorter form of the Czech version of the standardized McGill University questionnaire. The questionnaire survey was carried out with patients of the Centre for Demyelinating Diseases, Department of Neurology 1. LF UK and VFN in Prague, who were given a paper questionnaire. The information I obtained was processed into graphs and tables. The results showed that pain is present in 60 % of respondents with multiple sclerosis, most often localized in the spine and lower limbs. The intensity of...
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Use of electrostimulation according to Jantsche and Hufschmidt to influence triceps surae muscle spasticity and walking speed in patients with multiple sclerosis
Tichá, Simona ; Demeková, Júlia (advisor) ; Hojková, Klára (referee)
This thesis focuses on comparing the effectiveness of two types of electrostimulations, specifically electrostimulation according to Hufschmidt and Jantsche, in reducing m. triceps surae spasticity and influencing walking speed in patients with multiple sclerosis (MS). The aim of the thesis is to determine which type of electrostimulation is more suitable for patients with MS. The topic was chosen based on two previous theses that examined the effects of these electrostimulations individually. The theoretical part provides basic information about MS, explains the pathophysiology of spasticity and the possible influence of spinal mechanisms on it, describes the examination of spastic patients, and summarizes the possibilities of electrotherapy treatment. The practical part compares the effects of both types of electrostimulations in patients with MS who were partially randomly divided into two groups of three and evaluates short-term and long-term results using the "Five step clinical assessment in spastic paresis" examination and the subjective perception of walking questionnaire MSWS-12 (Multiple Sclerosis Walking Scale). The results of the thesis do not show significant differences in the effects of both electrostimulations. The most significant improvements in both groups were observed in the...
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