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Helicopter Drop of Money - Is It Feasible in Practice?
Gábrišová, Nela ; Holub, Tomáš (advisor) ; Adam, Tomáš (referee)
The main goal of this thesis is to discuss the famous Milton Friedman's concept of Helicopter Drop of Money in context of its applicability in the real world as a possible solution to liquidity trap. For better understanding, the thesis briefly de- scribes conduct of traditional and unconventional monetary policies. Key focus is put on describing assumptions necessary for the concept to yield desirable economic outcomes, and on detailed analysis of periods when zero lower bound on nominal interest rates is binding. Furthermore, roles of agents involved in execution of the concept, and important channels of transmission process are discussed from idealised theoretical view to real world possibilities of feasible execution. Additionally, prac- tical experience with direct cash distribution in Australia, and with quantitative easing programmes in Japan and the USA are explained. The last part analyses effects of increased monetary base on CPI inflation, money multiplier M2, and GDP in Japan and the USA using vector autoregression. JEL Classificiation E31, E43, E51, E52 Keywords Helicopter drop of money, quantitative easing, monetary base, liquidity trap, zero lower bound Author's email nela.gabrisova@gmail.com Supervisor's email tomas.holub@cnb.cz
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Molecular genetic and biochemical studies of selected inherited metabolic disorders, development and applications of new methods
Mušálková, Dita ; Hřebíček, Martin (advisor) ; Adam, Tomáš (referee) ; Macek, Milan (referee)
Inherited metabolic disorders (IMD) form a diverse group of several hundred different diseases with a relatively high cumulative incidence (stated up to 1:600). They are associated with accumulation of the substrates and lack of the products in specific metabolic pathways, which is caused by deficiency of the enzyme or its activator, or dysfunction of the transport protein. However, the underlying cause is at the DNA level. The grounds for different phenotype manifestation in patients with the same genotype are often not known. During my work at the Institute of Inherited Metabolic Disorders, I designed several new methods for the research of IMD and applied them in the patients and their families. I created procedures for the isolation of lysosomal membranes that are used for the research of lysosomal storage disorders and general properties of lysosomes. Next, I introduced several novel assays for determination of the X-inactivation ratio, which led to a significant increase of informative women. Nowadays, we use these methods in heterozygous women with X-linked diseases in order to study the influence of X-inactivation on the manifestation of the diseases. The cases of a girl with mucopolysaccharidosis type II, a girl with OTC deficiency and a family with the mutation in HPRT1 gene are described...
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Characterization of promoter regions of HGSNAT and GBA genes, and a contribution to the study of pathogenesis of MPS IIIC and Gaucher disease
Richtrová, Eva ; Hřebíček, Martin (advisor) ; Macek, Milan (referee) ; Adam, Tomáš (referee)
Pathogenesis of mucopolysaccharidosis type IIIC (MPS IIIC) and Gaucher disease has not been yet fully clarified, and the causes of phenotypical variability between the patients with the same genotype in Gaucher disease remain obscure. Because the variants in the regulatory regions of genes can cause phenotypical differences mentioned above, I have studied promoter regions of HGSNAT and GBA genes mutated in these lysosomal disorders. I have shown that there is an alternative promoter of GBA (P2). Additional studies were aimed to elucidate possible physiological functions of P2, and its possible role in the pathogenesis of Gaucher disease. I have found that P2 is not tissue specific, and that its variants do not influence the variability of phenotype in Gaucher patients with the same genotype. P2 is used differentially neither during the differentiation of monocytes to macrophages nor in macrophages from controls and Gaucher patients, in whom there is a prominent storage only in cells of macrophage origin. We have thus not found any changes that would suggest a role for P2 in the pathogenesis of Gaucher disease. I have characterized the promoter region of HGSNAT and shown that the binding of Sp1 transcription factor is important for its expression. Sequence variants found in HGSNAT promoter in...
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Utilization of laser welding methods for fixation of electrotechnical sheet bundles
Adam, Tomáš ; Kubíček, Jaroslav (referee) ; Mrňa, Libor (advisor)
Thesis deals with individual technologies of packaging stator sheets and their use in practice. The greatest emphasis is placed on welding technologies, especially on the differences between the individual methods. The experimental part of the thesis is focused on finding suitable parameters for welding the stator package using a laser with a special wobling head. The samples were evaluated in terms of penetration depth, the number of defects, especially pores and grain coarsening.
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Three essays on empirical Bayesian econometrics
Adam, Tomáš ; Komárek, Luboš (advisor) ; Feldkircher, Martin (referee) ; Herrala, Risto (referee) ; Melecký, Martin (referee)
The dissertation consists of three papers which apply Bayesian econometric techniques to monitoring macroeconomic and macro-financial developments in the economy. Its aim is to illustrate how Bayesian methods can be employed in standard areas of economic research (estimating systemic risk in the banking sectors, nowcasting GDP growth) and also in a more original area (monitoring developments in sovereign bond markets). In the first essay, we address a task which analytical departments in central banks or commercial banks face very often - nowcasting foreign demand of a small open economy. On the example of the Czech economy, we propose an approach to nowcast foreign GDP growth rates for the Czech economy. For presentation purposes, we focus on three major trading partners: Germany, Slovakia and France. We opt for a simple method which is very general and which has proved successful in the literature: the method based on bridge equation models. A battery of models is evaluated based on a pseudo-real- time forecasting exercise. The results for Germany and France suggest that the models are more successful at backcasting, nowcasting and forecasting than the naive random walk benchmark model. At the same time, the various models considered are more or less successful depending on the forecast horizon....
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Manipulation through Evaluative Voting in the State Cinematography Fund
Pham, Petr ; Gregor, Martin (advisor) ; Adam, Tomáš (referee)
The goal of this thesis is to examine the use of evaluative voting in the Board of the Cinematography Fund, which is responsible for the public subsidies in the film industry. A dataset covering results of calls for support in the period of 2013-2017 is used. A logistic regression model is constructed to assess the probability to succeed in such a call. Potential extent of manipulation among members of the Board is analysed with game theoretic approach, where agents misreport their true preferences. The results of this thesis are in line with the literature on social choice theory and suggest a great susceptibility to exploitation in the committee.
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Design and manufacture of an engraving LED laser
Adam, Tomáš ; Slaný, Martin (referee) ; Dvořák, Jaromír (advisor)
The thesis deals with the evaluation of achieved parameters of unconventional machining methods and their current use in practice. In addition, the design and construction of the prototype of the laser engraving device is carried out. Several tests are performed on the device and are compared with similar devices after evaluation. The entire construction is designed so that no special equipment is needed and the construction could be done in each workshop.
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Generalized Nash Equilibrium Problems in Economics
Kratochvíl, Maxim ; Červinka, Michal (advisor) ; Adam, Tomáš (referee)
The aim of the thesis is to provide basic overview of term called Gener- alized Nash Equilibrium Problem (GNEP), mainly to the audience with economic education. Given term is the generalization of famous concept coming from Game theory called Nash Equilibrium Problem (NEP). Thesis describes basic properties of GNEP, illuminates main differences between NEP and GNEP and provides examples of both models. Thesis discuss hy- pothesis that there might exist economic models that could be advanced or solved by GNEP. One example of such economic model is presented to support given hypothesis. Keywords Generalized Nash Equilibrium Problems, abstract economy, social equilib- rium problem, pseudo-game, application.
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