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Corporate Information Strategy
Hrabčak, Miroslav ; Souček, Tomáś (referee) ; Koch, Miloš (advisor)
Master´s thesis is focused on a presentation of entrepreneurial intention of corporate information strategy. The corporate information strategy is based on the analysis of current situation of the company and its environment which uses modern trends in IT business. It is about a complex solution which should help to the growth of turnover, strengthen of mark of company and stabilize the market position.
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Rail bridge over Morava river between Staré Město and Uherské Hradiště
Křivánek, David ; Štrba, Michal (referee) ; Pešek, Ondřej (advisor)
This diploma thesis deals with the design and assessment of a railway bridge over the Morava River between Staré Město and Uherské Hradiště on line No. 341. The existing railway bridge has a span of 20,5 + 60 + 20,5 m. Five different variants with different static systems were developed. All variants of the bridge steel structure were designed and solved with a lower orthotropic bridge deck. To select the final variant, all variants were statically assessed and compared using multicriteria analysis based on the selected criteria. The final variant was subsequently assessed in more detail according to the applicable standards.
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A Nodalization Study of Phebus FPT-1 Experiment in MELCOR 2.2
Cerny, T. ; Ptacek, M.
Phebus, an integral experimental facility located in France, is scaled down version of a French 900 MWe pressurized water reactor (PWR) by a ratio of 1/5000. The goal of the facility is to study phenomena occurring during light water reactor severe accidents and validate models and computer codes used for calculation of sever accidents. The aim of this paper is to compare different modelling approaches in MELCOR 2.2 computer code and the influence on thermal hydraulic behavior and core degradation in comparison with experimental results.
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Application of health education in Waldorf pedagogy
MUSELOVÁ STRETTIOVÁ, Anežka
The aim of this work is: to find what ways do they apply health education to a Waldorf-type kindergarten. The method of moderated semi-structured interview was used to determine the methods of application and the degree of their involvement in teaching in kindergartens with Waldorf pedagogy. The results of the findings cannot be generalized, they are subjectively focused (tied to) to two kindergartens with Waldorf pedagogy. The findings were fulfilled as expected, the rate of application was on a daily frequency, but the methods of application can be improved in many places. Especially in one of the kindergartens, healthy nutrition and the involvement of targeted exercise for development, can be improved. The work finds a new opportunity to participate in primary prevention in kindergartens.
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Evaluation of the Prediction Equations for Resting Energy Expenditure in Critically ill Patients
Tichá, Veronika ; Hronek, Miloslav (advisor) ; Herink, Josef (referee)
Charles University in Prague, Faculty of Pharmacy in Hradec Králové Department of Biological and Medical Sciences Candidate Mgr.Veronika Tichá Consultant PharmDr. Miloslav Hronek, Ph.D. Title of Thesis Evaluation of the prediction equations for resting energy expenditure in critically ill patients The inaccurate prediction of nutritional requirements of critically ill patients can cause overfeeding or underfeeding. It may lead to deceleration of repair processes, failure of organ function to fatal consequences. Indirect calorimetry is the most accurate method for assessment of energy requirements, but it not available in every intensive care unit. Thus, the purpose of this study was to evaluate accuracy of the prediction equations in critically ill patients and compare them with REE measured by indirect calorimetry. The study took place in the intensive care unit at FN HK during 8 months. Twenty patients were examined (mean age 35 years ± 16 years, BMI 27,8 kg/m2 ± 8,4 kg/m2 ). Measure of resting energy expenditure by indirect calorimetry were compare with REE calculate by using different nineteen prediction equations. Resting energy expenditure was on average 2166 kcal/d ± 552 kcal/d. Only these equations - Ireton-Liepa (2239 kcal/d ± 341 kcal/d; P = 0,6152; 103 % MEE), Ireton-Jones 1997 (2266...
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Site-directed mutagenesis of the human histamin H4 receptor: The role of Arg-341 in the interaction with cyanoguanidine - type H4R agonists
Ládová, Kateřina ; Skálová, Lenka (advisor) ; Pávek, Petr (referee)
Charles University in Prague Faculty of Pharmacy in Hradec Králové Department of Biochemical Sciences Candidate: Kateřina Ládová Consultant: Prof. Dr. Armin Buschauer Doc. RNDr. Lenka Skálová, Ph.D. Title of diploma thesis: Site-directed mutagenesis of the human histamine H4 receptor: The role of Arg-341 in the interaction with cyanoguanidine-type H4R agonists The human histamine H4 receptor (hH4R) was discovered in 2000. The H4R is supposed to be involved in immunological processes and is considered a potential drug target, e. g., for the treatment of inflammatory diseases. Cloning and expression of the hH4R inspired to the search for selective agonists and antagonists. Recently, UR-PI376 (2-cyano-1-[4-(1H- imidazol-4-yl)butyl]-3-[(2-phenylthio)ethyl]guanidine) was identified within a series of cyanoguanidines as a highly potent and subtype-selective H4R agonist with pronounced preference for the human over the murine H4R (mH4R). According to molecular modelling studies, the cyanoguanidine moiety of UR-PI376 forms charge-assisted hydrogen bonds with Arg-341 of the hH4R, suggesting this amino acid brings about selectivity for the hH4R over the hH3R and is the reason for the preference of UR-PI376 for hH4R over mH4R as well. To elucidate the role of this amino acid in the interaction with...
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Insolvency proceedings with a European international element
Šebková Stráska, Eva ; Smolík, Petr (advisor) ; Zoulík, František (referee)
in English In this thesis, I analyse Council regulation (EC) No 1346/2000 of 29 May 2000 on insolvency proceedings and its practical effects in EU member states' bankruptcy proceedings. The regulation creates a European insolvency law which is aimed at proper functioning of the internal market. The market requires efficient and effective cross-border insolvency proceedings in order to protect creditors. I review interpretations of the principle of controlled universality, Lex fori concursus, recognition of insolvency proceedings, and cooperation of liquidators whose function is to administer or liquidate assets located in various member states. I also examine the process of launching primary and secondary proceedings in relation to the debtor's centre of main interest and to his place of operations where the debtor carries out a non-transitory economic activity with human means and goods. I demonstrate the current legal reasoning of the Court of Justice of the European Union in e.g. the Judgment of the Court (Grand Chamber) of 2 May 2006 in Case C-341/04, Eurofood IFSC Ltd. which interprets Articles 1, 2, 3 and 16 of the regulation, and in the Judgment of the Court (First Chamber) of 21 January 2010 in Case C-444/07, MG Probud Gdynia sp. z o.o., which interprets Articles 3, 4, 16, 17 and 25 of the...
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Hellinger-Reissner Variational Principle Based Quadrilateral Finite Element
Středulová, Monika ; Eliáš, Jan
The Finite Element Method is without a doubt one of the most prominent tools in solving the equations governing mechanics of solids. It is an approximative method and, as such, its performance largely depends on the definition of the finite element used in a computation. The simplest elements, based on one primary field, tend to suffer from “locking”, that is excessive stiffness when an element is subjected to bending or the material is nearing the limit of incompressibility. One of the alternatives is the use of an element based on multiple primary fields. The present article aims to describe one such element (based on mixed-field Hellinger-Reissner variational principle) and analyze its robustness in comparison to other methods which were used in the past to mitigate locking. The analysis will be done in the framework of linear elastostatics.
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Motivation factors in prevalence of doping in fitnes centres visitors
Macho, Juraj ; Slepička, Pavel (advisor) ; Harsa, Pavel (referee) ; Krejčí, Milada (referee)
This thesis aims to specify the role of motivation in tendency to dope in a fitness environment. The aim reflects research questions focused on external and internal motivational factors and their influence on doping tendencies. We combine quantitative and qualitative research strategies to achieve this aim. The quantitative approach is based on the Theory of Planned Behavior (Ajzen, 1991) and the Self-Determination Theory (Deci & Ryan, 1985; Ryan & Deci, 2017). A total of 142 fitness center members (81 men and 61 women, age 30,2 ± 9,39 years) participated in this part of the study. In regression models, we observed some significant effects of the independent variables on variables stemming from the Theory of Planned Behavior. Specifically, we found a significant positive effect of external regulation (ß = ,195; p < ,05; R2 = ,324) and a significant negative effect of intrinsic motivation (ß = -,288; p < 0,001; R2 = ,324) in the model of attitudes toward doping. Furthermore, we found a significant positive effects of attitudes toward doping (ß = ,646; p < 0,001; R2 = 563) and doping offer in the fitness center (ß = 341; p < 0,001; R2 = 563) in the model of intention to dope. In the qualitative approach, we implemented a methodological framework of interpretative phenomenological analysis (IPA)...
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