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Modular Synthesis of Steroids by Negishi Reagent
Herrmann, Pavel
1 Introduction This dissertation is focused on the development of new methodology for the synthesis steroid derivatives. Steroids, due to their biological activity, still represent a favourite target of total syntheses. Many approaches for their preparation, based on transition metal-mediated or catalyzed reactions, have been developed. From the synthetic point of view, it would be ideal or at least highly desirable and interesting to develop a methodology based on the repetitive use of one reagent. Fortunately, such a strategy has not been published yet. To bring this methodology to life, it is crucial to use a suitable reagent that can selectively react with a wide variety of functional groups. In this regard, zirconocene derivatives seem to be potentially applicable as they display a broad reactivity. Hence, the main objective of this work is to elucidate the viability of their sequential use in the synthesis of complex natural compounds. 2. Aim of the Work The aim of this work is to develop a new synthetic methodology for the preparation of polycyclic isoprenoids. This methodology should be based on the sequential repetitive use of one reagent and should enable modular and flexible access to a wide variety of compounds. The appropriate reagent should function as a universal tool. Bearing the broad...
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Theory and Practice of Financial Analysis
Jakova, Ivana ; Taušer, Josef (advisor) ; Černá, Iveta (referee)
Analysts, managers or other business executives and students have at their disposal wide variety analytical techniques when they want to evaluate company's financial position or when they wish to better understand the financial implication of business operational activities or investment. This thesis examines the uses of financial analysis as one of the main financial assessment techniques. After describing theoretically the main tools of financial analysis, this thesis determines the practicality of these tools in evaluating the financial health of a car distributor company for the period from year 2002 to year 2009. Despite the fact that the analyzed company's core business is car distributor, this analysis takes into consideration also other activities of the company such as repair center because, as the analysis shows, it influenced the financial results of the company. This thesis is concluded with general outcomes from the financial analysis and with recommendation for the company in order to prevent potential risks and in order to improve its financial results.
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Financial analysis of Cukrovar Vrbátky, a.s.
Hronová, Lucie ; Mikan, Pavel (advisor) ; Vávrová, Hana (referee)
The object of this thesis is the financial analysis of the company Cukrovar Vrbátky, a. s. Its purpose is to provide the minority shareholder with the overview of the financial position of the company during the tracking period, so that it could serve as one of the information sources for his investment activities. The company is presented at the beginning of the thesis along with the sugar industry development. The introduction to the financial analysis theory follows, comprising the description of particular methods and tools applied by the financial analyst. The core of the thesis is the application of certain methods for the purpose of the evaluation of the company's financial situation within the years 2004 to 2008.
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Corporate Income Tax in Accounting
Šámalová, Marie ; Müllerová, Libuše (advisor) ; Zelenková, Marie (referee)
The aim of this thesis is to describe in detail the issue of accounting treatment for income tax of legal persons in accordance with current accounting and tax legislation. For a comprehensive understanding of the theory display the corporate accounting is appropriate to first deal with the two systems separately and only then proceed to define the operating results, respectively. tax base as one of the bridges connecting the two systems. Transformation operating results for the income tax base is outside the corporate accounting. Information provided by accounting systems are the most important basis for the determination of the tax at the entity. An integral part of this thesis is a detailed description of the accounting operations, which may be an entity in relation to tax corporate income to meet during the accounting, respectively. period. For clarity, the final part includes practical examples of application of the tax accounting theory.
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The status of animals as experimental objects in the light of wider sociological-historical perspectives
Vandrovcová, Tereza ; Suša, Oleg (advisor) ; Lupač, Petr (referee)
The thesis is dealing with the moral status of experimental animals in biomedical research. Aside of the sociological analysis of the problem, the aim of this work is to introduce a new field in social science Animal Studies, which is focused on elaborating the status of animals in human society and the relationships between humans and other living beings. In the first part, the author outlines the development of theories of moral status and evaluates the possibility of their application to the ethical problems related to nonhuman creatures. Practical part of the text is focused on the way the animals are objectified by laboratory personnel for the purpose of their instrumental use. The following chapter on the socialization of scientist focuses on the way the people are prepared and trained in emotional distance from the animals-instruments. Moreover, the author presents the process of desensitizing future scientist and discouraging individuals who are unable to accept specific concepts stabilized within the community of researchers who use animals. In the following part of the text the author describes the process of social construction of experimental animals as deindividualized objects representing the part of the laboratory and the negative effects that the consequent structure causes to animal...
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Field of ritual: a case study on the role of space in daily temple ritual of Gaudiya Vaisnavism
Huspeková, Tereza ; Ondračka, Lubomír (referee) ; Chlup, Radek (advisor)
temple ritual of the Gauóa Vaiavism. The work attempts to develop a theoretical approach to a particular set of empirical data by merging together various analytical concepts and theories from different levels of theorizing on ritual. The interpretation is based on a selection of empirical data from field research which was carried out in a local Gauóa Vaiava temple in Kolkata, West Bengal in 2007. The thesis consists of two parts, descriptive and interpretative. The descriptive part is ordered according to the main analytical concepts employed further in the process of theorizing. It contains textual and audio-visual materials providing a detailed description of the studied ritual environment seeking to enable the reader to enter the field of research. The interpretative part attempts to view the data through a 'focusing lens' of the concept of 'field of ritual' which shows that the ritual environment can operate as a responsive matrix structuring the actions of ritual actors which is further structured by them.
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Archetypes in economic analysis
Petráš, Jaroslav ; Rosický, Antonín (advisor) ; Šubrta, Václav (referee)
Transdisciplinary focused work concentrates on the possibilities of the application of the system thinking in the various science branches. Out of system disciplines it studies in detail the system dynamics -- specifically Archetypes (general structures). Introduction to the general system theory can be found in the first section of the theoretical part. Next sections are more particular and refer to the main ideas of system dynamics and Archetypes. Next part of the work focuses on common methods of the economic analysis. Apart from their brief description there is also discussion about their main theoretical flaws. The economic analysis of the specific socio-economic issue (road speed limits) is performed in the last part of the work and it includes substantial usage of the Archetypes and general system-thinking attitude. Primary aim of this part is to confirm or disprove the hypothesis of the utility of Archetypes in the economic analysis.
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Reed-Solomon codes and applications
Horal, Pavel ; Vojtěchovský, Petr (referee) ; Drápal, Aleš (advisor)
Xazev praee: Reed-Solomonovy kody a jejich aplikaco Autor: Pavel Iloral Katcdra (ustav): Katedra Algebry Vedouci bakalafsko prace: Doc. RNDr. Ales Drapal. CSc. c-nia.il vedoiiciho: drapar^karlin.mil', cuni.cz Abstrakt: Prace podava ucelenon definici klasiekyeh Reed-Solomonovych kodn, vcetne potfobuyeh zakladu tcxjric1 k()du. Je dokazana cykliciiost RS kodn delky q - I . Na cyklienosti jsou pak zalozeny tri inx'zontovane dekcklovac'i algoritmy fPetersonnv, Rorlrkain])-Mas.seyuv a Enklidi'iv dekodova.ci algoritmns), vcetne. dukazfi existcniee feseni. V ])oslodni ka])itole uvadiin nckolik a.]>likaci RS kodu, vcetne nejznainejyiho standardu CIRC' pouzivancho na Imdebnich CD. Klieova alova: .s;nnoo])ravny k(5d.1'X'C, Reed-Solomon. Pcterstm, Berlekanip-Massey. Euklid. CIRC1 Title: Rood-Solomon codes and applications Author: Pavel llora.1 Department: Department of Algebra Supervisor: Doc. HXDr. Ales Drapal, CSc. Supervisor's e-mail address: drapal (fkarlin.nirl.ouni.c/ Alislracl: This work presents compact definition of classic Heed-Solomon codes with necessary elements of coding theory. The ryclicity of RS codes of length q - 1 is prooved and there are comletely described three decoding algorithms (Peterson's, Berlekamp-Ma,ssoy and Euclid decoding algorithm) based on RS cyclirity. I also in- troduce a few RS...
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The relationship of information and graphic design - the application on certain marketing tools
Procházková, Magda ; Krsek, Libor (advisor) ; Horný, Stanislav (referee)
In today's world overcrowded of information is necessary to distinguish what is important and what is not. This helps the information and graphic design. The work explains the relationship between them and describes their principles. Than applies them to the elements of marketing mix such as product and promotion. The first part of this work deals with theories and principles. First describes the information design, its birth, discipline, informational designer and provides practical advice. In other part it deals similarly with graphic design. In the last part of the theory marketing describes marketing and marketing mix. Practical part first describes the relationship of information and graphic design. It refers to the interdependence and shows the differences between them. In other parts are applied information and graphic design rules on the elements of marketing. In the product part focuses on the logo and corporate identity, product design and product packaging. The promotion part evaluates the usage on the web promotion and printed promotion.
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