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Evaluation of investment project of the company Moravia Sport Group s.r.o.
Dudová, Martina ; Scholleová, Hana (advisor) ; Nováková, Soňa (referee)
The topic of the thesis is an evaluation of a real investment project of the company Moravia Sport Group s.r.o. with regard to the current and projected development of macro area, competitive environment and financial analysis results. The aim of this thesis is to give recommendations for the management of the company in order to decide whether to realize or reject the intended project. The theoretical part summarizes the basic analysis, the stages of the investment decision, the parameters entering into the investment evaluation and methods of their evaluation. In its practical part, the thesis initially presents the analysis of the external environment and inner potential of the company performed at first. Subsequently the investment project including its input parameters is introduced and an evaluation of the investment on the basis of defined methods is performed. The conclusion of the practical part is devoted to the sensitivity analysis and overall assessment of the investment plan.
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Pharmacotherapy of glaucoma
Konečná, Petra ; Hrdina, Radomír (advisor) ; Mladěnka, Přemysl (referee)
Charles University in Prague Faculty of Pharmacy in Hradec Králové Department of Pharmacology and Toxicology Candidate: Petra Konečná Supervisor: Doc. MUDr. Radomír Hrdina, CSc. Title of diploma thesis: Pharmacotherapy of glaucoma Glaucoma is one of the main causes of blindness in the world and its prevalence is progressively increasing. An early detection and an effective therapy are very important to prevent progression of this disease. Ways of treatment involve pharmacotherapy and laser or surgical interventions. The diploma thesis is concerned with pathophysiology, classification and detection of glaucoma. The main part focuses on a medical treatment, especially on individual groups of medications, which are used from the initial stage of the disease to maximally tolerated doses. Prostaglandin analogs, which are currently used as the first line of therapy and which are used with other medications in fixed or unfixed combinations, are described in detail. Glaucoma is unfortunately incurable but it is possible to prevent its exacerbation and an irreversible loss of sight. The thesis follows up and summarizes results from international studies dealing with an effect, an effectiveness and side effects of single groups of medications. The purpose was to organize new observations in one complex and...
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Development of non-professional scenic dance 1945 - 1968
Smugalová, Zuzana ; Gremlicová, Dorota (advisor) ; Lössl, Jiří (referee)
This master thesis surveys historical development of non-professional art of dance in the Czechoslovak Socialistic Republic during politically complicated era after the Second World War. It follows trends of scenic dance and dance education, initially influenced by social realism and subsequently by the arrival of jazz and modern dance techniques. It summarizes facts about organisational provision of non-professional activities in the field of art, including the system of displays, festivals and competitions. It brings an outline of the state of dance education in the area of spare-time activity. Thus it allows to look into the era that is stigmatized by today?s prejudice caused by the same black and white vision for which the era itself had been noted.
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Monetary policy of the European Union
Drbohlavová, Jana ; Jeníček, Vladimír (advisor) ; Abrhám, Josef (referee)
The purpose of this thesis is to sum up the evolution of monetary policy of the European Union so far and to review the impact of the global financial crisis upon the euro area outlining its future. The other purpose is to analyze the Maastricht convergence criteria fulfillment by the Czech Republic and to sum up if the Czech Republic is or isn't ready to enter the euro area and to adopt the common currency. The first and the second part of the thesis are more descriptive of dealing with the historical evolution of monetary policy from the initial formation in the European Economic Community to the origin of the European Monetary system. The third part brings the reader particular information about the Economic and Monetary union and phases of its foundation. It also brings about the European Central Bank which is the most important institution for monetary policy of the European Union and in the end summarizes the advantages and disadvantages of adopting the common currency. In the fourth part I try to assess the impact of the global financial crisis upon the states of the euro area and mention the view of experts on its future. The last chapter deals with the potencial entry of the Czech Republic to the euro area. That review is based on the analysis of the Maastricht convergence criteria fulfillment.
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Mediation as a method of international dispute resolution
Hána, Lukáš ; Peterková, Jana (advisor) ; Havlová, Radka (referee)
Mediation is currently the most frequently used method for the resolution of armed conflicts in the international relations. Thanks to the participation of a neutral third party as a mediator it is possible to conduct peace negotiations even in the cases when participants are not willing to communicate directly with each other. The study summarizes the basic theoretical knowledge concerning the mediation, describes mediator's role, different forms and styles of mediation and other factors, that have influence on it. This knowledge is applied to the two case studies. Summits in Camp David in 1978 and 2000 are described in terms of initial conditions, course, participants and their styles of negotiation and last but not least their success. By comparing these two summits, the author formulates conclusions, which reflect the mediation efforts by the United States of America in their endeavor to settle the Palestinian-Israeli conflict and which highlight the greatest difficulties of the peace talks.
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Information Education in Italy: Projects and Activities in Academic Environment
Klimešová, Pavlína ; Landová, Hana (advisor) ; Dombrovská, Michaela (referee)
This thesis deals with the issue of information education in Italy and focuses primarily on projects and activities in the academic environment. This thesis deals with the issue of Information Education in Italy and focuses primarily on Projects and Activities in the Academic Environment. In the introductory chapter several theses are formulated, regarding Italian environment in relation to Information Literacy and Information Education. In the second chapter many aspects and challenges of Information Education in Italy are briefly zoomed - a system of legislative efforts on the path towards the Information Society, a characteristics of the current state of Higher Education and Information Education at universities, the interpretation of terms Information Literacy and Information Education and their terminological pitfalls in Italian, characteristics and tools supporting Information Education, the issue of Plagiarism. The third chapter discusses several major Italian initiatives (including one European, based in Italy) from a non academic sphere. The fourth chapter discusses the status of libraries and librarians in Italy and their role in the educational process. The fifth chapter is devoted to analysis of specific Information Literacy Projects in selected Italian universities. The conclusion summarizes...
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Old Czech legends and their current treatment
Brožková, Lucie ; Brožová, Věra (advisor) ; Hrabáková, Jaroslava (referee)
Resumé The thesis is focused on the processing of old Czech legends in literature for children. The aim is to show how the writers adapted legend the children. The initial treatment the Old Czech Legends by Alois Jirásek. The theoretical part deals with legends, its types, legends in the folk tradition and legends in children's literature. The practical part is interpreted five books of legends from children's literature. Interpretation shows different ways that authors use to approach reputation child readers, or even shift the topic, if any. The conclusion summarizes the findings arising from the interpretation.
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Criminological aspects of crime recidivism
Oliberiusová, Jitka ; Tlapák Navrátilová, Jana (advisor) ; Marešová, Alena (referee)
The issue of criminal recidivism represents a significant social problem. The aim of this thesis is to analyze the problematics of criminal recidivism, gather available information related to this topic, evaluate current measures used to counter recidivism and propose possible ways of increasing their efficiency The thesis consists of five main chapters, which are divided into smaller subchapters. Chapters are focused on different aspects of criminal recidivism. The initial foreword is followed by the first chapter, which is focused on different perceptions of the term "recidivism". Subchapter describes dealing with recidivism in terms of its recourse (nebo sanctioning) within the Czech legal system. The second chapter reflects the current state of recidivism in the Czech Republic. It shows that the statistics concerning recidivism within the whole concept of criminality differ in judicial, police and prison statistics according to different perceptions of this term. The third chapter summarizes the causes of criminal activity. It is divided into two subchapters. The first part looks at the "outer"causes of recidivism. As a specific cause it refers to imprisonment, which is analyzed to higher extent. The second part presents the recidivist's personality and its role in committing illegal...
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Usage of antibodies and immunoconjugates in the pharmacotherapy of cancer
Vaidlová, Alena ; Čečková, Martina (advisor) ; Mladěnka, Přemysl (referee)
4 ABSTRACT Charles University in Prague Faculty of Pharmacy in Hradec Králové Department of pharmacology and toxicology Candidate: Alena Vaidlová Supervisor: Pharm.Dr. Martina Čečková, Ph.D. Title of diploma thesis: Usage of antibodies and immunoconjugates in the pharmacotherapy of cancer. This diploma thesis display posibility of tumor treatment by antibodies, their conjugates and antibody fragments. Antibody therapy uses natural antibody binding of tumor cell or other abnormal cell. Antibodies bind only cells with cellular biomarkers which are present on target cells. Binding initiate disposal process of damaged cell. Genetic engineering helps to create different antibodies and their conjugates with different qualities, especially various affinity to specific structures they recognise. Unconjugated antibodies are chimerical, humanized, pure human or pure murine. Conjugated antibodies are represented by imunoconjugates, conjugates with cytostatics, with enzymes, with phytogenic or animal toxines. Developement of antibodies has totally new phenomenon - creating of antibody fragments. These elements are products of genetic engineering and their utilization has a great future. This work summarizes the latest knowledge about using monoclonal antibodies and immuoconjugates in theanticancer therapy.
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Data Governance Implementing Method
Slouková, Anna ; Slánský, David (advisor) ; Pour, Jan (referee)
This thesis refers to Data Governance issue and the way of implementing this program. It is logically devided into two parts -- theoretical and practical one. The teoretical part represented by first chapter summarises actual findings about the Data Governance program, it explains what is hidden behind the term Data Governance, cause for Data Governance initiatives emergence, it itemizes particular parts of which the program is composed and basic, mostly software tools, that are necessary for successful program run. Practical part consists of second and third chapter. The second chapter contains enumeration of various types of outputs that grow up either during the implementation of program or in its run itself. It categorizes and deals in detail with processes and activities, organizational structure of the program, dokuments, used metrics and KPIs and IS/IT tools. Third chapter describes the process of implementing the program into an enterprise in detail. It is devided into four consequential phases -- assessment of current state, design, implementation and run of the program. In every chapter, there are inputs, outputs, detailed decomposition into particular activities with references to document tepmlates that are used during theese activities, risks and resources introduced. In two attachments of this thesis, there are two helpful documents -- general document teplate and teplate of a role description -- that serve to better implementation of Data Governance program.
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