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Electronic information resources in the Information Department of the Institute of International Relations
Heringová, Hana ; Bratková, Eva (advisor) ; Kolátorová, Helena (referee)
Práce má za cíl popsat elektronické informační zdroje informačního oddělení Ústavu mezinárodních vztahů v Praze a navrhnout pro ně skupinu dalších využitelných elektronických zdrojů. První část práce identifikuje informační potřeby uživatelů prostřednictvím popisu oboru mezinárodních vztahů a činnosti ústavu. Druhá část práce prezentuje jednotlivé zdroje, jež má oddělení v současnosti k dispozici, s ohledem na jejich podstatné vlastnosti a jejich hlavní přínos pro uživatele služeb oddělení. Poslední část zpracovává obdobným způsobem elektronické zdroje volně dostupné v prostředí internetu, navržené jako doplněk stávajících zdrojů.
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The study of molecular and biochemical bases of cytochrome c oxidase deficiency
Veselá, Kateřina ; Zeman, Jiří (advisor) ; Farghali, Hassan (referee) ; Drahota, Zdeněk (referee)
This thesis has been worked out in The laboratory for study of mitochondrial disorders (Department of Pediatrics, 1st faculty of Medicine, Charles Univezity in Praha), which serves as the diagnostic center for patients from Czech and Slovak Republics. During the last years, more than 40 children with isolated COX deficiency were diagnosed in our lab. But molecular background except 12 patients with mutations in SURF1 gene was remaining unknown. Due to the lack of adequate treatment for these patients, the genetic counseling and the possibility of prenatal diagnostics have high importance for the families. The possible dual origin of the defect with different hereditary aspects makes the genetic counseling in the affected families complicated and prenatal diagnostics based only on biochemical analyses very problematical if even possible. This work had been arisen basically from the necessity to find the molecular background of isolated COX deficiency in our patients. In addition of simple characterization of molecular background and optimalization of methods for routine diagnostics, we were able to study the impact of several mutations in nuclear genes for COX assembly factors on the biochemical, structural and histochemical level in affected tissues.
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Education of patients before an elective cholecystectomy
Žampachová, Milada ; Schneiderová, Michaela (advisor) ; Vachková, Eva (referee) ; Horáčková, Alexandra (referee)
Author: Žampachová Milada Institution: Institute of Social Medicine LF UK in Hradec Králové, Departement of Nursing Title of the work: Education of patients before an elective cholecystectomy Supervisor: Mgr. Schneiderová Michaela Prim. MUDr. Svoboda Jiří Number of pages: 105 Number of attachments: 13 Year of the defence: 2010 Keywords: Education, Cholecystectomy, SILS, Preoperative and postoperative care, Dietotherapy The Bachelor Thesis is focused on the education of patients before an elective cholecystectomy. The theoretical part is divided into two chapters. The first one concentrates on the education of patients, defines it and describes communication principles of the educational process, documentation and the competence of paramedical sanitarian staff to educate. The second chapter is dedicated to the cholecystectomy itself, where the anatomy and physiology of the gallbladder, diagnosis of the pathologies, surgical treatment, preoperative and postoperative care and principles of the diets following are described. The main objective of the empirical part is a quantitative research survey obtained by questionnaires aimed at discovering whether the education of patients undergoing an elective surgery is of adequate quality and uncovering areas needing improvement. This work is based on a...
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Burn injury as a hard life situation, its different perception and managing between women and men
Kuglerová, Simona ; Píbilová, Agata (advisor) ; Šauerová, Daniela (referee) ; Klein, Leo (referee)
Burn injury as a hard life situation, its different perception and managing , between women and men. The baccalaureate thesis deals with burn injury as a hard life situation, its different perception and managing between women and men. Emphasis of the thesis is placed on a subjective and different perception and managing of the burn injury between interviewed men and women which were hospitalized. My interest was focused not only on the identification of the subjective perception of the burn injury, but also to determine differences in perception and managing the burn injury on the basis of used questionnaire method of examination. Emphasis of the thesis is formed by research investigation on the inpatient adult unit (department) at Burn Centre in Praque, Teaching hospital Královské Vinohrady. Purpose of this work is to compare differences of perception and managing hard life situation during burn injury between man and women, as well as to evaluate the subjective perception and managing of the burn injury on the selected population of patients.
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Use of NMR in structural analysis of natural products
Dohnalová, Hana ; Špulák, Marcel (referee) ; Kuneš, Jiří (advisor)
This Diploma work is dedicated to the determination of the structure of unknown substances. A large number of alkaloids was isolated from an Eschscholtzia Californica plant (Papaveraceae) at the Department of Pharmaceutical Botanic and Ecology of the Pharmaceutical Faculty in Hradec Králové. Some of them were passed to the Laboratory of the structure and interaction of the biological aktive molecules along with the request for the structure analysis.The main object of this Diploma work was the identification of three of unknown subjects by the help of NMR analysis. The structures of unknown substances were identified on the basis of the NMR experiments (1 H-NMR, 13 C-NMR, DEPT, ghmqc, ghsqc, ghmqfcops a dpfgnoe). These structures were confirmed based on the comparison with the data provided in the subject publications. Now identified substances belong to isochinoline alkaloids. Namely, it is scoulerine and retikuline. The third substance was not specified in the subject publication.
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Biochemical and mechanical processes in synovial fluid - modeling, analysis and computational simulations
Pustějovská, Petra ; Málek, Josef (advisor) ; Süli, Endré (referee) ; Jäger, Willi (referee) ; Maršík, František (referee)
vi Title: Biochemical and mechanical processes in synovial fluid - modeling, mathematical analysis and computational simulations Author: Petra Pustějovská (petra.pustejovska@karlin.mff.cuni.cz) Department: Matematický ústav UK, Univerzita Karlova v Praze Institut für Angewandte Mathematik, Universität Heidelberg Supervisors: prof. RNDr. Josef Málek CSc., DSc. (malek@karlin.mff.cuni.cz) Matematický ústav UK, Univerzita Karlova v Praze, Prof. Dr. Dr. h.c. mult. Willi Jäger (jaeger@iwr.uni-heidelberg.de) Institut für Angewandte Mathematik, Universität Heidelberg Abstract: Synovial fluid is a polymeric liquid which generally behaves as a viscoelastic fluid due to the presence of polysaccharide molecules called hyaluronan. In this thesis, we study the biological and biochemical properties of synovial fluid, its complex rheology and interaction with synovial membrane during filtration process. From the mathematical point of view, we model the synovial fluid as a viscous incompressible fluid for which we develop a novel generalized power-law fluid model wherein the power-law exponent depends on the concentration of the hyaluronan. Such a model is adequate to describe the flows of synovial fluid as long as it is not subjected to instantaneous stimuli. Moreover, we try to find a suitable linear viscoelastic model...
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Evaluating the with successfulness of playing actions of an individual in women's volleyball at the Olympic games in Beijing 2008
Němcová, Eva ; Pokorný, Ladislav (advisor) ; Jahodová, Gabriela (referee)
Tittle: Evaluating the with successfulness of playing actions of an individual in women's volleyball at the Olympic Games in Beijing 2008 Author: Eva Němcová Department: Department of physical training Supervisor: PaedDr. Ladislav Pokorný, Katedra tělesné výchovy Pedagogické fakulty Univerzity Karlovy v Praze, M. D. Rettigové 4, 116 39 Praha 1 Supervisor's e-mail adress: pok.lad@email.cz Abstract: This thesis is intended for interested people from general public, firstly as educational materials for a narrow group of teachers and coaches of volleyball on high schools, sports grammar schools, etc. The thesis includes chapters focused on history, characteristics of particular playing actions of an individual, playing systems, combinations and playing achievements. The research deals with successfulness of playing actions of an individual in women's volleyball at the Olympic Games in Beijing 2008. Keywords: volleyball, playing actions of an individual, spike, serv, block, digging, reception
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The Linguistic Characteristics of a Baroque Legend
DOLEŽALOVÁ, Zdeňka
Main topic of this work is to analyze language elements used in the legend from baroque period and that from the complete conception on the gross information contents this work and characteristic features of phonetics and morfology. No research in the field of syntax and lexicology was made at this point (our final work would be to extensive). The complete interpretation refers to father Jiří David´s baroque legend Medicus Hercinius, {\dots} dated 1713. First part we apply to common informations about the author, about the period, in which he lived and wrote his legend, and about his contemporaries. We describe the legendistic literature and conditions to her expansibility in our country, the life of saint Gunther then and the substance of whole David´s work in general. There are important informations about noted humanismus and baroque authors in next two chapters. We describe individual phenomens of two language levels phonetics and morfology then, especially with regard to theory and practice. Principal aim of my work is to contribute to o deeper understanding of Czech language from the late baroque.
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The young and their lifestyle.
Brož, Michal ; Jílek, Petr (referee) ; Klusoňová, Hana (advisor)
Michal Brož Young people's lifestyle Diplomová práce Univerzita Karlova v Praze Farmaceutická fakulta v Hradci králové Studijní obor: Farmacie Background: - to define a situation in the area of using legal and illegal habit forming substances among students at the age from 16 to 20 years - to analyse the dependence of development of psychic problems on using habit forming drugs Methods: - questionnaire study: anonymous questionnaire (contains questions on smoking, alcohol, habit forming substance and the BSI form) - opened, closed and semi closed questions - 343 students (106 males, 2237 females) at the age 16 - 20 years (average age 18,58 year) - data analysed in SPSS for Windows, version 16.0 Results: Legal substances: - 57,4% of students have an experience with smoking tobacco - only 17,8% of respondents smoke regularly and only 8,7% smoke daily - 86,9% of students have an experience with drinking alcohol Illegal substance: - 39,7% have an experience with using illicit substance (47,2% male and 36,3% female) - the most frequently used drug is marijuana (32,7%), then hashish (13,7%), Cocaine (8,7%), sleeping pills (7,3%) and amphetamine and LSD - as the most dangerous substance are considered heroin, cocaine, ecstasy, LSD, methadone and amphetamine Psychical disorders: - a two-sided...
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Evaluation of activity of potentional antifungal substances through the use of microdilution broth method I.
Nitraiová, Jindřiška ; Paterová, Pavla (referee) ; Vejsová, Marcela (advisor)
1. Abstract Jindřiška Nitraiová Evaluation of activity of potentional antifungal substances through the use of microdilution broth method I Diplomová práce Univerzita Karlova v Praze, Farmaceutická fakulta v Hradci Králové Farmacie The aim of the thesis was a screening of activity of new potentional antifungal substances. For testing of substances was used the microdilution broth method. This method allows a routine assesment of MIC of a larger amount of antimycotics and also complete strains. The compounds for the strains Candida albicans, C. tropicalis, C. glabrata, C. krusei, Trichosporon beigelii, Aspergillus fumigatus, Absidia corymbifera a Trichophyton mentagrophytes were tested. The derivates of pyrazinedicarbamide, pyrazinedicarbothioamide, pyrazole-1- carboxylate, hydrazinecarboxylate, diazene-1,2-dicarboxamide and cyclohexanone did not show any antimycotic effectiveness. On the contrary the derivates of benzamide and benzenecarbothioamide showed a good antimycotic activity against all the testing strains. In the group of other substances, it means the derivates of pyrazinecarboxamide, pyrazinecarbothioamide, pyrazine-anilides, pyrazine-2-amine, pyrazine-2-carbohydrazide and pyrazine-2,5-dicarbonitrile and thiazolidine-4-one, some substances were effective but some had no effect. The derivates of...
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