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B- and T- lymphocyte subpopulations in lymphocyte-associated immunodeficiencies
Šinkorová, Vendula ; Kalina, Tomáš (advisor) ; Javorková, Eliška (referee)
The antigen-specific immunity consists of cells called T and B lymphocytes. These cells together with cells of non-specific (innate) immunity begin their development in fetal liver and later in bone marrow from the common progenitor, the hematopoietic stem cell. Both B and T lymphocyte lineages then undergo differentiation which is regulated by many cytokines and transcriptional factors and leads to very heterogeneous cohort of subsets. Because the immune system is not only protecting the organism from infections and malignant growth but also from itself, lymphocyte differentiation must pass many checkpoints where B and T clones are strictly selected. Cells of both lineages closely communicate with each other and also with cells of innate immunity. If, due to mutation of protein encoding genes, disturbance of differentiation or malfunction of effector activities providing some of these functions occurs, an immune system malfunction called immunodeficiency arises. Multiparametric immunophenotyping followed by flow cytometry examination has been proven one of the most suitable techniques for studying lymphocyte subsets and lymphocyte- associated immunodeficiencies. Here we describe examples of primary lymphocyte- associated immunodeficiencies, how they affect individual lymphocyte subsets, what it...
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Merleau-Ponty and the beginings
Urbanová, Kateřina ; Janoušek, Jaromír (referee) ; Šulová, Lenka (advisor)
This work whishes to open phenomenological paradigm in child psychology. It is inspired by the philosophy of Maurice Merleau-Ponty. It, at first, foreshadows his thinking, which is not very extended in czech psychology. So, it discusses the relationship between psychology and phenomenology too. Then it tends to put down how it is possible to understand some aspects of infant perception. The pivotal part of the work is a consideration about the nature of the "beginings" of our life and about how their conception influences developmental psychology at all. We try to find out what gives a fashion and direction to the development of man. Hier, it takes advantage also from others fenomenological authors. The result of this work is summary of the phenomenological view on child and it's development. It suggestes non-privative conception of child and it's world. It couldn't be uderstanded only as an imperfect wolrd of adults. We show, that the task of the other people is rather "to introduce" a child to the world.
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Professional Competencies od Coach - Pilot study
Zemanová, Vladěna ; Rychtecký, Antonín (referee) ; Kovář, Karel (advisor)
Title: Coach's Key Competens -pilot survey Author: Vladena Zemanovd Goals of thesis: Based on the theoretical part of my final thesis, I tried to conduct a survey, which has never been conducted before. It was supposed to show two aspects of a trainer's job. The first one is education (based on a model of a new concept of lifelong education) and the second one is the importance of key competence in activities of a trainer. Methodology: I made a questionnaire, which is divided into two parts. The first one is about the education and it's called Trainer Q and the second one is called Competence Q, which asks the respondents questions connected to particular activities in different dimensions of key competence. Results: I was successful at making a pilot questionnaire, which could be useful in future surveys. Additionally, the part of the questionnaire about the activities in particular dimensions of key competence can be tested. Key words: trainer, key competence, education, abilities, skills, personality
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School assessment and its influence on the child
Boldišová, Lenka ; Stará, Jana (advisor) ; Kargerová, Jana (referee)
UNIVERZITA KARLOVA v PRAZE Pedagogická fakulta katedra primární pedagogiky ŠKOLNÍ HODNOCENÍ A JEHO VLIV NA DÍTĚ SCHOOL ASSESSMENT AND ITS INFLUENCE ON THE CHILD Vedoucí diplomové práce: PhDr. Jana Stará, Ph.D. Autor diplomové práce: Lenka Boldišová Studijní obor: učitelství pro 1. stupeň ZŠ Forma studia: kombinovaná Diplomová práce dokončena: březen, 2012 ABSTRAKT: In the theoretical part the problems of evaluation in contemporary education will be analyzed. The attention will be particularly focused on the collection of information based on influences of the evaluation and its individual forms and types on the child. In the empirical part the combination of quantitative and qualitative methods will be utilized. In the quantitative part of the research, questionnaires for elementary schools teachers, for pupils of the primary school grade 2 to 5 and the parents of those pupils will be used. The questions will be focused on their attitude to the different forms of the school evaluation - what they are mainly afraid of, what they prefer, what attitude they have to self-evaluation, how they are influenced by the different forms of evaluation. In some detailed dialogues with pupils, their parents and their teacher I will examine the way of evaluation of pupils in the elementary school and to what degree their...
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Liability in employment law
Koubalíková, Lucie ; Procházková, Eva (referee) ; Štefko, Martin (advisor)
97 Liability in labour law Summary This diploma paper analyzes liability in labour law with focus on liability for damage. At first the diploma paper introduces conception of liability in general and idea of liability in labour law considering different position of employee and employer in labour relations. The diploma paper then enumerates the types of labour-law liability. The next chapter concentrates on liability for damage. This chapter describes characteristic features of liability for damage and prerequisites for occurence of liability for damage. Functions of liability for damage are detailed as well, namely prevention of damage. The following chapter elaborates liability for damage of an emloyee and an employer. This analysis includes general liability and special types of liability in order to compare types of liability for damage. The chapter contains specification of compensation for damage. The final chapter mentions brief comparison of liability for damage of an emloyee and an employer, labour-law liability and civil-law liability and evaluation of actual legal arrangement with regard to distinction between former and currently valid Labour Code. The diploma paper gives attention to application of legislation, practical cases, experiences described in expert literature and jurisdiction in...
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Hannah Arendt's concept of thought and action
Štech, Daniel ; Němec, Václav (referee) ; Kouba, Pavel (advisor)
The present thesis follows the distinction made by Hannah Arendt between the life of the mind and vita activa. In her earlier writings, Arendt presents acting in concert as a supreme human possibility. The devaluation of active life in the Western tradition is seen as related to the subordination of the experience of action to the experience of thought, which presupposes a turning away from the world of phenomena and plurality. With respect to the ability to act, Arendt understands thought as marginal or even detrimental. On this note, she contrasts thought with opinion, a specifically political attitude bound to the experience of action and plurality. Following the process with Eichmann, however, this image saw a revision. With the collapse of the public sphere, the dependence of the ability to tell right from wrong on the activity of thought became more prominent. Subsequent considerations therefore shift to the sphere of the mind. In the light of the corpus of Arendt's works, the present thesis enquires into the nature of mental acts required for adequate action. The first part presents political thought within the situation of plurality. The second part takes into account the collapse of the public sphere and deals with the uneasy relationship between thought and the ability to relate to the common...
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Valuation of Infineon Technologies AG
Drotár, Martin ; Jurečka, Jan (advisor) ; Makovec, Martin (referee)
The aim of this thesis is evaluation of the public company as a whole as well as on a one share basis (intrinsic value)and comparison of these values with the values based on a market price. Cash flow methods and market multiples were used in a valuation. Autor is trying, apart from the valuation itself, to analyse impact of the global economic crisis on the value of the company.
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Painful States of Wrestlers
Vodrážka, Zbyněk ; Hošek, Václav (advisor) ; Hátlová, Běla (referee)
Cizojazyčné resumé: The graduation theses approaches problems of pain and pain conditions during the Greco-Roman wrestling, together with some factors which can this incurred pain accompany and/or influence. Main objective of this thesis is to explore how much and which way the pain influences an achievement of wrestlers in a match or in training, and how the pain is perceived by wrestler. Next ~etect which stand-point coaches have in the problems of pain of their wards, and how these access wrestlers themselves perceive. An important component will also be inquest of intension of pain, whereby the wrestler is obliged to scratch an important or ordinary match, and intension of pain when he/she stop to coach. No less important it will be some findings how often the wrestler run in a match with some ache and how often he/she finish the match with some ache. Iťs ascertained that accident rate of wrestlers is quite higher than accident rate of other sportsmen. This thesis should also identify body parts which are the most strained by combat sport. Key words: wrestling, acute pain, chronic pain, muscleskeletal pain, measurement ofpain
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Hegel s concept of civil society
Svojše, Jiří ; Skovajsa, Marek (advisor) ; Muhič Dizdarevič, Selma (referee)
This master's thesis is concerned with Hegel's concept of civil society. After an introduction of the contemporary normative concepts of civil society and their research potential, it provides a detailed description and interpretation of Hegel's concept, with a special emphasis on three major interpretative approaches. The final part of the thesis also includes the author's own interpretation of this concept.
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