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Possibilities of waste treatment in iron and steel industry
Mlčoch, Jakub ; Louda, Jiří (advisor) ; Petrášek, František (referee)
Metallurgical industry annually produces several hundred thousand tones of metalliferous wastes, which contain beside of the oxides of iron, metallic and non-metallic iron also the compounds such as zinc and lead, which are both environmentally and, secondly, preventing the recycling of this waste in metallurgical process in the production of pig iron and steel. The management of this waste, according to the valid legislation, the producer of the waste is burdened by the costs in the form of charges for uploading to a secure landfill or disposal of third parties. At the same time experience a loss of metallic substance contained in the waste, which would be used as a substitute for iron ore in the metallurgical process. Currently occurs on the part of the EU, the pressure to minimize waste, while emphasis is placed on the back of recovery (recycling). This pressure is also reflected in the increase in charges for storing waste, forcing enterprises to innovate in the field of recycling technologies. The correct settings and the use of recycling technologies implies reduction of production costs, which can be discerned from the economic calculation in the application section of the work, that handle with a specific value of the fee for storage of waste.
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Synthesis of NK1 antagonists.
Puchnerová, Lucie ; Doležal, Martin (advisor) ; Zitko, Jan (referee)
Synthesis of NK-1 antagonists Lucie Puchnerová Department of Organic and Pharmaceutical Chemistry, Faculty of Pharmacy University of Seville NK-1 receptor antagonists are represented so far by only one drug, Aprepitant, which is available on the market for prevention of chemotherapy-induced nausea and vomiting. Nevertheless, it is assumed that NK-1 antagonists will be able to participate in treatment of migraine, rheumatoid arthritis, asthma, pain, inflammatory bowel disease, Parkinson's disease, anxiety and depression in future. This thesis is concerned with asymmetric synthesis of derivatives of 2-amino-4H-pyran, which thanks their substitutions are in accordance with structure of pharmacophore of NK-1 antagonists. As a starting material for their preparation has been used commercial methyl p-tolyl sulfone and (R)-methyl p-tolyl sulfoxide, which was synthesized from menthyl-(S)-p- toluenesulfinate by nucleophilic substitution. These compounds were subjected to reaction with ethyl 2-picolinate. From prepared β- ketosulfoxide and β-ketosulfone were obtained 2-amino-4H-pyrans by Michael addition. The derivatives proceeding from β-ketosulfoxide were subjected to reduction of the sulfoxide and trifluoroacetylation of the amine group on the carbon 2 of the pyran ring. Prepared derivatives had agonistic activity...
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Social aspects of people with poliomyelitis
PODHORSKÁ, Jitka
How it is a consequence of that title, this extended essay deals with problems of people suffering from poliomyelitis (infantile paralysis). Thanks to the systematic vaccination, this disease has not been found in the Czech Republik since the 1960s. The people who had got over paralysis after acute poliomyelitis in a successful way were feeling sureness for years. The return of the illness, respectively its late consequences after a few decades of a normal life means a change-over from the state of full or - as the case may be {--} only mildly reduced abilities to the state of lifelong invalidity for them. Handicapped people have to get over great numbers of obstructions and limits which arise partly from the existence of hte certain handicap and which are given by the handicaps {--} limits the organization of the society put in their way in the course of ist development in parts. Over recent years, the Czech Rebublik has ranged with the countries which realize a greater responsibility for the elimination of barriers keeping the handicapped citizens away from a full - value participation in the life of the society. The aim of the essay was to obtain a comprehensive view of possibilities of keeping social needs of people suffering from poliomyelitis {--} infantile paralysis and to evaluate the barriers which have to be got over by that group. It was also a very important thing to find the quality of life and satisfaction with a realization of aims of life as far as people suffering from poliomyelitis and to compare it with the quality of life as regards the current population. Three following hypotheses were set in line with this aim. Hypothesis No 1: In spite of the current legislation concerning the elimination of architectonic barriers, the handicapped people are limited in the participation in the public life. Hypothesis No 2: Considering the dependence on the other person´ s aid, the people suffering from postpoliomyelitis syndrome appreciate financial guarantees ensuing from the social service law in a high degree. Hypothesis No 3: The quality of life of people suffering from poliomyelitis is reduced, in comparison with the quality of life as far as healthy people. Hypothese 1 and 2 were confirmed by my research, hypothesis No 3 was not verified. The detailed analysis of the given hypotheses is included in the part of discussion in the extended essay. With respect to the relevance of the mentioned topic I suppose that the obtained results could be a contribution to the organizacions dealing with questions if the handicapped people . The essay can be presented at a public meeting of Assotiatin Polio various specialists and the lay public take part in.
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Patent protection for medicaments and its topical issues
Kučera, Jan ; Pítra, Vladimír (advisor) ; Růžička, Michal (referee)
- 61 - 7. Resume - Patent protection of pharmaceuticals and its current problems The pharmaceutical industry nowadays plays a major role in the world's economy, having an estimated total volume of USD 740 billion and being one of the recognized key innovation sectors. The system of patent law is of major significance to the industry in that the monopoly it confers, for a limited period of time, on using innovations provides a major incentive for innovative research activities that the industry is involved in. Although the availability of patent protection for chemical and pharmaceutical products has, from a historical perspective, only been reaffirmed in the near past, it has nowadays been accepted as a global standard mainly through the provisions of the WTO's TRIPS agreement. Despite the existence of various international treaties harmonizing patent laws, patents have to date in their effects remained strictly limited to individual jurisdictions. There're several ways of how patents can be used to protect the novel, innovative and non-obvious results of pharmaceutical research; patents for end products, processes of making a product or for new medical indications can mainly be of practical use, each of these types providing a different scope of protection and offering different approaches of preventing...
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Vliv sportovních odvětví s jednostranným zatížením - HOKEJ - na poškození páteře a pohybového aparátu
PEROUTKA, Michal
Abstract This bachelor thesis discusses the issue of impact of specific ice-hockey movement on the player{\crq}s locomotory system. The thesis was aimed to identify the occurrence rate of spinal damage and locomotory system function disorders in a selected set of top sportsmen. The strategy of this bachelor thesis is based on quantitative research. A standardized interview and observation methods were used for data collection. It includes clinical examination methods of aspection, palpation and testing. Photos and videos were used to obtain more accurate evaluation of some clinical examinations. The acquired data were tabulated and a positive finding rate was evaluated in percentage. The set under evaluation was created by random selection with the following criteria: - Respondent is a top ice hockey player - Respondent player{\crq}s position is defender or forward The set includes 60 members who are divided in three sections by age categories of the Rules & Regulations of the Czech Ice Hockey Association. In addition, this breakdown provides information on whether the damage rate of occurrence depends on how long the player has played the sport. The survey results confirmed a hypothesis that ice hockey contributes to spinal damage and locomotory system function disorders. This thesis should provide another piece of evidence that the player{\crq}s locomotory system is not adequately considered in the training process. It is documented that although this issue is mentioned in training methods, preventive and corrective actions with respect to inflicted locomotory system injuries are not sufficiently used in practice.
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Computer games and Internet addiction among second grade pupils of elementary schools: a comparison of urban and rural populations
Kramářová, Simona ; Vacek, Jaroslav (advisor) ; Vondráčková, Petra (referee)
The theme of this thesis is Computer games and Internet addiction among second grade pupils of elementary schools: a comparison of urban and rural populations. Its documents are the scientific literature and studies on the subject and the results of research conducted in the period from March to May 2012. The aim of this thesis is to find a prevalence of addictive behavior on the Internet and PC games among second grade pupils of elementary schools, to compare the prevalence of urban and rural population and to identify factors associated with this dependency behavior. Theoretical part is divided into six chapters. There are briefly described addictive and impulsive disorders, and further described dependency theories on the Internet / PC games, diagnostic criteria and symptoms by which this dependence may be identified, for comparison with my results there are the results of prevalence studies of defects observed in comparable populations. The thesis also focuses on the characteristics of the target groups and character traits, which are described in the problem users of the Internet/ PC games, protective and risk factors for the emergence and development of addiction to computer games and Internet, as well as prevention and treatment of these disorders. The practical part consists of a research...
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Business Plan of Wedding Agency
Klocová, Lucie ; Tyll, Ladislav (advisor) ; Strouhal, Jiří (referee)
This thesis focuses on a creation of the business plan of a wedding agency. The theoretical part is devoted to the analysis of individual parts of the business plan. In the practical part I will apply this knowledge to a specific foundation project, with a regard to the functioning principles of wedding agencies in our country and also to competitor analysis. The result is a unique business plan, which should succeed in current real conditions. In the end I focuse on possible risks associated with this type of business and try to find the best method how to prevent and control them.
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Cyberbullying
Hášová, Gabriela ; Vítečková, Michaela (referee) ; Pelikán, Jiří (advisor)
Bullying has never been easier. Thanks to boom in informations a comunications technologies, almost anybody, in privacy of their houses, in anonymity of PC classroom or internet caffés, can bullying almost whosever. 24 hours a day, 7 days a week. Also this can be a form of cyberbullying. What cyberbullying is, what are the specifics, what are the most common forms, who are aggressors, who are targets, how many young people has encounte with cyberbullying not only all around the world, but also in Czech Republic. How school staff, parents and targets have to react, when a problem with cyberbullying has appared. What are the possibilitis of prevention. I have tried to respond on following next pages to those questions.
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The Motivation Issue of Upper Primary Students
Mazúchová, Ráchel ; Sedláčková, Daniela (advisor) ; Kasíková, Hana (referee)
The aims of this thesis is to map all issues related to learning motivation (or lack of it) of upper primary students. It tries to analyze factors that reduce or complicate motivation at school and it focuses on the most common consequences of frustration in school environment - boredom and anxiety. It also deals with possibilities how to arouse cognitive, achievement and social needs which play the key role at school, and it attempts to answer questions about the ways a teacher can increase upper primary students' motivation for learning, taking into account the specifics of their ontogeny. Special attention connected with this issue is devoted to the influence of teacher-pupil interaction. The empirical part provides insights from practice, these insights are regarded as a complement of the theoretical part.
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Electronic records of sales as a tool to eliminate tax evasion
Bělinová, Marcela ; Pikola, Pavel (advisor)
This thesis deals with the prevention of evasion of tax control implementation instruments, namely the introduction of electronic evidence in revenues. The first part defines basic terms as tax, inspection tool, the Tax Code, tax compliance and more. There is mentioned view of tax administration in terms of legislation. Then describes the tools for eliminating tax evasion, zoom their operating principles of electronic evidence in sales in the Czech Republic. Definition of the problem, the reasons for introducing targets entities required to record sales, the subject of electronic evidence in revenues, mandatory data sanctions measures, the impact on businesses and the public budget. Work is in its second part deals with the evaluation of electronic evidence in revenues as a tool for professional elimination of tax evasion in the Czech Republic, Evaluation of Options Croatian model as a model for the introduction of evidence of sales in the Czech Republic. Based on information mapping pozice Czech Republic
Croatia to introduce the EET This will also assess the suitability or otherwise of the election of Croatia as a model for the introduction of EET in the Czech Republic.
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