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Qualitative research in the aplication of desinfection and sterilization of nursing unit
KARBÁČOVÁ, Marika
Abstract The thesis focuses on the application of disinfection and sterilization in the surgical unit. These methods are an integral part of nursing care and they prevent creation, transmission and spread of infection. The qualitative research was carried out in the surgical department in the Hospital Prachatice a.s.. The method used in the research is an unstandardized in-depth interview, in the second phase extended to a structured observation. There were set three objectives. Objective 1: to determine the ways of application of disinfection in the surgical unit, Objective 2: to determine the ways of application of sterilization in the surgical unit, Objective 3: to determine whether nurses observe the principles of disinfection and sterilization in the surgical unit. On the basis of these objectives, there were formed three research questions: What types of applications are used for disinfection in the surgical unit? What types of sterilization applications are used in the surgical unit? What principles of disinfection and sterilization are observed in the surgical unit? From the results of the in-depth interview and observation, it was discovered that physical and chemical disinfection is applied in the surgical unit. The employees use the services of central sterilization. In the surgical unit, there is not used any type of sterilization, except of the pre-sterilisation preparation. While disinfection, the employees follow the correct procedure, but they do not always use the correct amount of disinfectant. As the possibility of improvement, I would suggest to carry out training and remind that the recommended concentrations of disinfectants are sufficiently effective. There is no need to increase their amount hence it increases the financial costs of the surgical unit.
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Business process analysis of RWE CZ
Mizera, Jiří ; Pour, Jan (advisor) ; Lebeda, Adolf (referee)
Práce se zabývá analýzou podnikových procesů a procesního řízení v plynárenské společnosti RWE CZ. Konkrétní analýza pak probíhá v již vytvořeném jednotném procesním modelu RWE CZ tzv. Master Modelu. Kromě analýzy struktury Master Modelu a důvodů jeho zavedení, je prakticky analyzována skupina procesů Nákup. Jednotlivé druhy modelů v rámci Master Modelu jsou tak vysvětleny na konkrétním příkladě a na závěr jsou navrženy kroky pro zlepšení. V úvodu je věnována kapitola s obecnými definicemi podnikového procesu a podnikového informačního systému a jejich vzájemnými vztahy. Dále jsou pak definovány obecné požadavky na informační systémy v energetice a je provedena stručná analýza nabídky ERP produktů, v tomto odvětví. Teoretické poznatky nabyté v úvodní a v následující kapitole jsou prakticky poukázány na příkladu RWE CZ. Celá práce je potom zaměřená primárně na ekonomické systémy používané v energetice a důraz je kladen na efekty plynoucí z nasazení těchto systémů, jak informatické tak ekonomické. Závěr práce je věnován především harmonizaci informačních systémů v rámci skupiny RWE v ČR, zvláště pak nasazení systému SAP IS-U.
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Financial analysis of PSP engineering, a.s.
Červinková, Hana ; Mikovcová, Hana (advisor) ; Bernátová, Marcela (referee)
The purpose of this work is to carry out financial analysis of a manufacturing company which is aimed at discovering of its total financial health, present progress and is also trying to evaluate future perspective. In the methodological part there are selected methods and procedures of financial analysis characterized which are applied also in the practical part. This part is composed of several sections. In the introduction the company PSP engineering a.s. is introduced, also its focus and present progress in recent years is presented. As the first extensive analysis including horizontal and vertical analysis of financial balance and income sheet is carried out. After that selected methods of financial analysis are applied which will help to judge the financial health and general position of this company.
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Study of interspecies differences in plasma protein binding of 18F-labeled radiopharmaceuticals
Pašková, Barbora ; Konečná, Klára (advisor) ; Jílek, Petr (referee)
Mgr. Barbora Pašková The study of antimycotic activity of newly synthetized substances Rigorous thesis Charles University in Prague, Faculty of Pharmacy in Hradec Králové Study program: Pharmacy Background: The aim of this rigorous thesis was to evaluace the antimycotic activity of 77 substances prepared at the Department of Inorganic and Organic Chemistry, Faculty of Pharmacy in Hradec Králové of Charles University in Prague. Method: The substances were tested by the microdilution broth method and all substances were tested at eight strains of yeasts and filamentous fungi. The tested substances were divided into five groups according to their chemical structure to salicylanilide carbamates, sulfoneamide ureas - derivates of sulphamethoxazole, sulphonamide imidazolidinetriones - derivates of sulphamethoxazole, derivates of isoniazide and substances with disunited structure. Results: The highest antimycotic activity was discovered in group of salicylanilide carbamates. There were tested 28 derivates of this group, from which 18 of them showed antimycotic activity. On the other hand, substances from group of derivates of isoniazide showed no antimycotic activity. The most susceptible strain was Trichophyton mentagrophytes and the most resistant was strain Aspergillus fumigatus. Conclusions: To...
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Analysis of value added tax with focus on construction and installation works
Batistová, Petra ; Vopátek, Jiří (advisor) ; Kozlová, Taťána (referee)
The work focuses on the issues of VAT and taxation system in the Czech Republic. The theoretical part describes the history of taxes and basic terminology. The core of the work is the second part, which is devoted to analyze the impact of various tax VAT Act amendments to the tax payers, with a focus on construction and assembly works. The goal is to solve the practical problem - the application of various amendments to the VAT Act in terms of construction and assembly work. Calculation is carried out and then compared the impact of amendments to the VAT Act on the price of construction and assembly works. Another practical example describes how the reverse charge regime translates into recognizing and completing VAT returns in a construction company.
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Analyze of working satisfaction
Mašátová, Jana ; Stříteský, Marek (advisor) ; Rys, Luboš (referee)
The aim of thesis was summed up the basic theoretical knowledge, to identify the fundamental factors of working satisfaction, to analyze working satisfaction to identify the factors of working satisfaction and dissatisfaction. Based on the results of research propose new measures how to improve dissatisfaction. In this thesis was used a questionnaire survey and structured interviews. A questionnaire was used for technical-economic employees and workers. Structured interviews were conducted with five top managers. Respondents were asked about satisfaction with the content of work, remuneration, promotion of personal development and career growth, the human relations and working conditions. In conclusion they were asked about their relation to the company in which they work.
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The molecular mechanism of CSL protein participation in oxidative stress response in Schizosaccharomyces pombe
Daněk, Petr ; Převorovský, Martin (advisor) ; Sipiczki, Matthias (referee)
Redox homeostasis maintenance is important for proper organism and cell function, for while relatively low amount of reactive oxygen (and nitrogen) species contributes to the fine tuning of signal transduction, excessive concentration of ROS (oxidative stress) has demonstrably harmful effects and is tightly connected to many pathological states. Cells therefore evolved broad palette of antioxidant mechanisms that express striking level of conservation among different species. Large, intricate stress response signaling networks have been already described; nonetheless, novel molecules employed in stress-related signaling are still being discovered. Several studies recently suggested transcription factors CSL, proteins essential for regulation of metazoan development as effectors of Notch signaling, are also involved in response to oxidative stress. The fission yeast Schizosaccharomyces pombe, well established model of response to various stresses, comprises two paralogs of CSL proteins - Cbf11 and Cbf12. We have found cells depleted of cbf11 are highly resistant to hydrogen peroxide. This resistance appears to be caused by upregulation of important stress responsive genes including ctt1, gst2, pyp2, and atf1. Cbf11 is therefore negative regulator of these genes, which suppresses their expression...
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Decompilation of High-Level Constructions in C++ Binaries
Jakub, Dušan ; Křivka, Zbyněk (referee) ; Matula, Peter (advisor)
The thesis addresses the decompilation of high-level object-oriented C++ language from a machine code. The term reverse engineering is defined and existing decompilers are described with emphasis on their ability to reconstruct C++. AVG decompiler project is introduced, to which this thesis contributes. C++ language is analysed, both on a logical level and in the machine code and existing methods of decompilation are described. On this basis a novel method is introduced, capable of decompiling classes, their hierarchy, constructors, destructors and definitions and usages of virtual methods. The method is implemented, tested and evaluated. In the conclusion, several suggestions for future development of this project are presented.
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Using modern technology in economic education
Krejčík, Jan ; Krpálková Krelová, Katarína (advisor) ; Krpálek, Pavel (referee)
The bachelor thesis ,Using modern technology in economic education, is focused on a problem with integration technology (smarthphone, tablets and others) into a normal economic classes in high schools. First, technical part, describes each individual device and different kinds of operating systems they use. Second part describes results from other researches about similar topics. Third, didactic part, is focused on didactic technology, e-learning, m-learning a new theories in education. Fourth part includes my own research about using modern technologies by students and teachers in high schools and brings analysis of discovered information. Final part gives practical recommendation for pedagogical practice in teaching economical subjects.
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Business rule learning using data mining of GUHA association rules
Vojíř, Stanislav ; Strossa, Petr (advisor) ; Pour, Jan (referee) ; Kouba, Zdeněk (referee) ; Gregor, Jiří (referee)
In the currently highly competitive environment, the information systems of the businesses should not only effectively support the existing business processes, but also have to be dynamically adaptable to the changes in the environment. There are increasing efforts at separation of the application and the business logic in the information system. One of the appropriate instruments for this separation is the business rule approach. Business rules are simple, understandable rules. They can be used for the knowledge externalization and sharing also as for the active control and decisions within the business processes. Although the business rule approach is used for almost 20 years, the various specifications and practical applications of business rules are still a goal of the active research. The disadvantage of the business rule approach is great demands on obtaining of the rules. There has to be a domain expert, who is able to manually write them. One of the problems addressed by the current research is the possibility of (semi)automatic acquisition of business rules from the different resources - unstructured documents, historical data etc. This dissertation thesis addresses the problem of acquisition (learning) of business rules from the historical data of the company. The main objective of this thesis is to design and validate a method for (semi)automatic learning of business rules using the data mining of association rules. Association rule are a known data mining method for discovering of interesting relations hidden in the data. Association rules are comprehensible and explainable. The comprehensibility of association rules is suitable for the use of them for learning of business rules. For this purpose the user can use not only simple rules discovered using the algorithm Apriori or FP-Growth, but also more complex association rules discovered using the GUHA method. Within this thesis is used the procedure 4ft-Miner implemented in the data mining system LISp Miner. The first part of this thesis contains the description of the relevant topics from the research of business rules and association rules. Business rules is not a name of one specification of standard but rather a label of the approach to modelling of business logic. As part of the work there is defined a process of selection of the most appropriate specification of business rules for the selected practical use. Consequently, the author proposed three models of involving of data mining of association rules into business rule sets. These models contain also the definition of a model for the transformation of GUHA association rules in the business rules for the system JBoss Drools. For the possibility of learning of business rules using the data mining results from more than one data set, the author proposed a knowledge base. The knowledge base is suitable for the interconnection of business rules and data mining of association rules. From the perspective of business rules the knowledge base is a term dictionary. From the perspective of data mining the knowledge base contains some background knowledge for data preprocessing and preparation of classification models. The proposed models have been validated using practical implementations in the systems EasyMiner (in conjunction with JBoss Drools) and Erian. The thesis contains also a description of two model use cases based on real data from the field of marketing and the field of health insurance.
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