National Repository of Grey Literature 25 records found  beginprevious16 - 25  jump to record: Search took 0.01 seconds. 
Infectious diseases and migration
Vostrá, Jana ; Dzúrová, Dagmar (advisor) ; Seidlová, Markéta (referee)
The topic of this diploma thesis is Infectious diseases and migration. Its aim is to assess the distribution of selected infectious diseases in the world and in Europe, with a focus on Czech context. While from the literature it can be concluded that the spread of serious infectious diseases is conditioned by migration, based on the available data it cannot be confirmed that immigration currently constitutes a significant threat for Czech citizens.
Latitudinal trends in prevalence and diversity of parasites and pathogens of vertebrates
Wichová, Eliška ; Albrecht, Tomáš (advisor) ; Reif, Jiří (referee)
The latitudinal diversity gradient (LDG) indicates a decrease of species richness from equatorial regions toward poles and it is known as a biogeographical pattern applicable for the majority of free-living animals and plant species. Many hypotheses link this phenomenon with a high measure of biotic interactions at low latitudes, which play an important role in the origin and maintenance of species diversity. One of these interactions is the host-parasite relationship. The aim of this thesis is to summary recent investigations of parasitic and pathogenic occurence according to latitude for representative groups of host vertebrates with focus on diversity (number of infectious species per host species) and prevalence (the total number of infected cases per whole population at specific time). Using comparative approaches was revealed, that latitudinal gradient in richness and prevalence is characteristic particularly for vector-born parasites of terrestrial vertebrates and ectoparasites of marine fish.
Periodic Water Bodies and Their Biota.
Bušová, Tereza ; Říhová, Dagmar (advisor) ; Škodová, Jana (referee)
This thesis is focused on a description of small periodic water bodies and their biota. These telms are formed as a result of heavy spring rains, floods, melting snow or the ground water level rising. They are formed on green parts, non-green parts or fallen parts of a plant (in that case they are called phytotelmes), in water-filled tree-holes (dendrotelmes), in fissures of rocks (lithotelms) or in various cavities, artificially created by human - in empty jars, water- filled tires, flower-holding vases in cemeteries etc. The thesis deals mainly with dendrotelmes and phytotelmes which are the most frequent, especially in tropics. It provides the information about their formation and animals that lives in these small habitats. Also, a taxonomical review of the main reported fauna was added for better orientation of the reader. The most common taxa which occur in temporary pools are families of mosquitoes (Culicidae), chironomids (Chironomidae) and ceratopogonids (Ceratopogonidae). There are also present other Dipteran larvae or larvae of scirtid beetles from the family Helodidae. Some of the animals living in the pools used different evolution strategies to be well adapted to deal with periodicity and drying out of the water bodies. Their overview is also included in this thesis. Furthermore,...
The relation of the population's health condition and the system AB0.
Pavlíková, Zuzana ; Peterka, Miroslav (advisor) ; Likovský, Zbyněk (referee)
This work is a summary of observations about relationships between AB0 blood groups and occurrence of certain diseases. To diseases mentioned in this work belong different types of cancer, malaria, leprosy, small-pox, vitiligo and many others. Marked association with AB0 blood groups was found for cancer of stomach, ovarian cancer, peptic ulcers and cholera. The results for other diseases are not evident or on their relationship to blood groups were not made enough confirmative studies.
Adumbration of Malaria in Africa
Houšková, Barbora ; Kofroň, Jan (referee) ; Frajer, Václav (advisor)
This bachelor thesis is devoted to malaria, its geografic extension and the fight against this illness. Malaria affects tropics and subtropics and mainly on the African continent the malaria influences lives of millions inhabitations. Disease is caused by the parasite Plasmodium, which is transmitted by mosquitoes. As a result of extreme poverty associated with lack of protection and prevention against the malaria, this illness is causing major problems in Africa. Fight against malaria is long and more or less unsseccful for the present. At the beginning of this thesis is characterization of the disease, this thesis is devoted geografical extension of malaria, the most detailed description is devoted the most disabled states of Africa. At the end of the thesis are given economic and social consequences of malaria. Key words: malaria, tropics and subtropics, Third World, the fight against malaria
Microfinance: Development Aid Tool
Klačková, Zuzana ; Taušer, Josef (advisor) ; Černá, Iveta (referee)
In the 20th century, microfinance went through a revolution: the number of microfinance was expanding exponentially all over the world. Microfinances are supposed to be one of the most efficient tools in alleviating poverty. The paper, Microfinance: Development Aid tool is analyzing whether microfinance institutions provide, beside the credit services, also preventive antimalarial services so as to lower malaria cases. Theoretical part is focused on definition and familiarization with 'microfinance, development aid and malaria' terms. Practical part analyses the malaria problem in connection with microfinance market and microfinance organizations in the three above mentioned countries.
9-[2-hydroxy-3-(phosphonomethoxy)propyl] ("iso-HPMP")derivatives of purine bases and their side-chain modified analogues: synthesis and antimalarial activity
Krečmerová, Marcela ; Holý, Antonín ; Hocková, Dana ; Dračínský, Martin ; Keough, D. T. ; Guddat, L. W.
Hypoxanthine and guanine iso-HPMP derivatives substsituted in 2´-position were prepared and studied as potential inhibitors of a key enzyme of the malarial parasite Plasmodium falciparum HGXPRT.
Use of 1,3-dioxolanes in the syntheses of alpha-branched alkyl and aryl N-9-[2-(phosphonomethoxy)ethyl]purines
Pomeisl, Karel ; Holý, Antonín ; Krečmerová, Marcela
Syntheses of various alkyl and aryl substituted N-9-[2-(phoshonomethoxy)ethyl]purines from a number of 2-alkyl(aryl)-1,3-dioxolanes were developed in preparative yields. The cleavage of a dioxolane ring with Lewis acids was chosen for preparation of suitable phosphonate building blocks as a key reaction step followed by their Mitsunobu reaction with purine bases. Obtained phosphonate derivatives were tested as potential HG(X)PRTase inhibitors. In contrast to previously published N-9-[2-(phosphonoethoxy)ethyl]purines, no inhibitory activity towards this enzyme was observed.
Phenotyping of a glutamate dehydrogenase a null mutant of \kur{Plasmodium falciparum}
PERNER, Jan
Glutamate dehydrogenase a (GDHa) has been suggested as a potential drug target against the malaria parasite Plasmodium falciparum. GDHa knockout cell line was generated and needed a phenotypic description by means of molecular biology and biochemistry. The knockout cell line was tested for higher oxidative stress sensitivity, levels of relevant proteins and gene transcripts were quantified. Furthermore, concentrations of two key molecules enabling redox homeostasis, glutathione and NADPH, were attempted to quantify. Finally, we attempted to disrupt a gene of another glutamate dehydrogenase, gdhb, which did not result in formation of viable parasites. In conclusion, GDHa is not a suitable drug target and GDHb needs to be further elucidated.
Medical care and diseases in the developing countries
KRČMÁRIKOVÁ, Lucie
This diploma thesis focuses on HIV/AIDS problematics in Africa. Africa is a continent most affected by the HIV/AIDS epidemic. Two thirds of all HIV positive individuals (25,8 milion)live in sub-Saharan Africa. Among others, spreading the HIV virus is also the result of some traditions and social and cultural custome. The extent of the HIV/AIDS epidemic in Africa is also connected with the deterioration in the epidemiologic situation of other serious infections, tuberculosis and malaria in particular. Uganda is country that has manager to stop the HIV/AIDS epidemic. The WHO{\crq}s estimations show that 10-12% of HIV positive individuals live in Uganda. Another problem faced by Uganda is a high perinatal and maternal death rate, whose decrease is one of the Uganda goverment{\crq}s priorities.

National Repository of Grey Literature : 25 records found   beginprevious16 - 25  jump to record:
Interested in being notified about new results for this query?
Subscribe to the RSS feed.