National Repository of Grey Literature 14,430 records found  beginprevious14421 - 14430  jump to record: Search took 0.41 seconds. 

Sport, myth and popculture. An outline of several possible culturological views of existence, distribution, perception and interpretation of the sport and agonal principle in contemporary Western society
Děkanovský, Jan ; Czumalo, Vladimír (advisor) ; Matějů, Martin (referee)
v teto pn3ci jsme se pokusili za pomoci kulturologickych instrumentu nahlednout fenomen sportu v soudobe zapadni spolecnosti. Nas zajem smeroval ale spise k zachyceni a charakteristice zrcadleni tohoto fenomenu v kultui'e nez k uchopeni fenomenu sameho. Vychazeli jsme z pi'edpokladu, i.e nejvetSi cast recipientU se se sportem setkava v podobe kulturniho textu, jenz vznika distribuci sportu masovymi medii. Tento kulturni text jsme posleze podrobili blizsi analyze a nastinili jsme nektere moznosti jeho interpretace. Musime konstatovat, ~e v ceskych podminkach - na rozdil od zapadnich zemi - jde pravdepodobne 0 zatim specificky a ojedinely pokus. I u nas Ize zajiste nalezt celou i'adu nejruznejsich publikaci 0 sportu, vcetne praci odbornych. Zpravidla se tyto prace ale zamei'uji na zakladni sociologicke zkoumani, muzeme nalezt nespocet del ze sportovni historie a bylo by mozne jmenovat i pokusy 0 aplikaci filosofie na fundament sportu, jimz je minena zejmena specificka telesna cinnost. Pokud jde 0 zrcadleni, resp. vliv sportu na kulturu, byva kladen duraz na idealni podobu sportu: tedy sport coby mediator uslechtilych myslenek, zasad fair play apod. Jinou castou oblasti zkoumani jsou pak negativni projevy jiste casti recipientu - divaku, ktei'i ducha sportovniho soupei'eni zamenuji za ryzi nasili (napi'....

Synthesis and study of ceramide analogues
Školová, Barbora ; Vávrová, Kateřina (advisor) ; Matějka, Pavel (referee) ; Šklubalová, Zdeňka (referee)
Charles University in Prague, Faculty of Pharmacy in Hradec Králové Department of inorganic and organic chemistry Candidate: Mgr. Barbora Školová Supervisor: doc. PharmDr. Kateřina Vávrová, Ph.D. Title of doctoral thesis: Synthesis and study of ceramide analogues Ceramides (Cer) together with free fatty acids and cholesterol form intercellular lamellar space of the uppermost skin layer (stratum corneum, SC). This lipid matrix presents the proper skin barrier - it protects organism against outer environment and keeps its homeostasis as well. The composition and arrangement of the intercellular lipid matrix is essential for the skin barrier properties. In spite of this fact, the organization of SC lipids at the molecular level is not fully elucidated. The aim of this work is to contribute to more detailed insight into organization of skin barrier using SC lipid model membranes, in particular to find the structural parameters in ceramide molecules, which play a role in the maintenance of the skin barrier. The SC model membranes present a useful tool to study SC lipids, they mimic physiological or pathological conditions in the skin. The obtained results should be used in diagnosing or therapy of skin diseases characteristic with impaired barrier function, such as atopic dermatitis or psoriasis....

Project and realisation of a ropes course in the selected region
Laža, Matěj ; Frainšic, Michal (referee) ; Vomáčko, Ladislav (advisor)
Name of the bachelor essay: Ropes course - project and execution of the project . The goal of this bachelor essay is to create a complete step-by-step document of a rope center realization in the Recreational and sport center U Starého Rybníka in Zbraslavice by Zruč nad Sázavou. The reader will be briefly introduced to the history and development of the rope centers and the following environmental education. Further it offers the description and the extended current processes and means necessary to build a rope way, which we later on implicate into the practice in a real rope center with 7 rope obstacles. The methods used in the period of creation of this bachelor essay were firstly collection of the data from Czech as well as international literature and experiences of the professionals in fields that directly concern rope activities. Gathered data were used for the proposal of a rope center project, which was approved and later on indeed realized. The result of our work is the collection of experiences and knowledge, which offers to the reader a complete view of the rope center building process from the very first project until the first step on the rope obstacle. Keywords: ropes courses, Experiential Learning, wire rope, u-bolt wire rope clip

Physiotherapeutic procedures in patients with rheumatoid arthritis with maximum difficulties in the joints of the hand area
LEDVINOVÁ, Eva
This bachelor thesis is focused on physiotherapeutic methods used in patients with rheumatoid arthritis whose difficulties are mainly in the joints of their hand. Rheumatoid arthritis is a chronic inflammatory joint disease in most cases with a protracted course and it may cause joint deformations. These lead to handling issues which complicate normal daily activities of the patients. Thus this disease causes both physical disability of the patient and as well significantly disrupts their social and psychological life. In the first part, which is concerned with theory, I briefly outlined the functional anatomy and kinesiology of the upper limb and shoulder girdle. Furthermore there is a detailed description of rheumatoid arthritis, definition of the disease, its causes and occurrence, clinical features, laboratory and x-ray examination, differential and functional diagnosis and all the treatment possibilities. In the conclusion of theoretical part there is the prognosis of the disease and practical difficulties during the care of patients with rheumatoid arthritis. The aim of this thesis is to map the possibilities of physiotherapy in patients with rheumatoid arthritis and the use of physiotherapeutic procedures and methods in individual patients with this disease. The qualitative research method, in which three patients treated in Berta Spa in Třeboň participated, was used for the practical part of the thesis. The therapy was initiated by an entrance kinesiological analysis, including the specific examination such as the examination of joint-play in small joints of hands, examination of the gripping, palpation of muscle tonus in muscles of the upper limbs and goniometric examination of joints of the upper limbs. This was followed by nine individual therapies, during which we focused mainly on upper limb joints. At the last session an output kinesiological analysis was conducted and the patients were taught about the necessity to comply with regime measures. At the end they spoke about their subjective feelings connected with the therapy and with their Balneotherapy stay in the spa. The results of the treatment were recorded for each individual case. This bachelor thesis may serve as an educational material for students in medical fields, general public to increase awareness of rheumatoid arthritis and last but not least for patients themselves or their families.

Laboratory diagnostics of micrometastases in breast cancer patients
Mikulová, Veronika ; Zima, Tomáš (advisor) ; Svoboda, Marek (referee) ; Průša, Richard (referee)
Introduction: The presence of circulating tumor cells (CTC) in the peripheral blood has been associated with worse prognosis and early relapse in breast cancer patients. CTC determination in the peripheral blood has been considered as a liquid biopsy. The aim of this project was to analyze the presence of CTC followed by their molecular characterization with the potential use not only as a new biomarker for real-time monitoring of therapy efficacy but also as a suitable tool for patient's stratification and individualization of treatment for breast cancer. Methods: A total of 54 patients with diagnosed early breast cancer were enrolled into a prospective study. Ten millilitres of peripheral blood were sequentially collected to test for the presence and characterization of CTC during the follow-up of patients. CTC isolation and detection was performed by AdnaTest BreastCancer™ (AdnaGen AG, Germany), which is based on the detection of EpCAM, HER2 and MUC1 specific transcripts in enriched CTC- lysates. cDNA from isolated CTC has been further used for newly optimized qPCR assays for breast tumor and therapy resistance associated genes: TOP1, TOP2A, CSTD, ST6GAL, KRT19 and reference gene actin. qPCR results have been analyzed by Genex software (MultiD Analysis). Results: 195 blood samples have been...

Study of Factors Influencing the Development of "Water Bloom" in the Water Reservoir Seč
Forczek, Sándor ; Holík, Josef ; Rederer, L. ; Koza, V.
In this work, we monitored several parameters that influence the development of algal bloom on the\nwater reservoir Sec. Primarily climatic conditions belong to the monitored parameters that influence\nthe population dynamics of algae (air temperature and rainfall, incident light), temperature\nstratification of water, concentration of oxygen, concentrations of total phosphorus, phosphate,\nvarious forms of nitrogen and organic substances, turbidity and also diversity and frequency of\nphytoplankton and zooplankton species. Between 2012 and 2014 have not occurred massive algal\nblooms in the summer months, however the measured physical, chemical and biological data, can be\nused to assess the development of algal population. The population dynamic factors influencing algal\ngrowth must be understand to be able to predict formation and to attempt suppression of algal\nblooms.

Inflation And Real Income Of Households In View Of Public - January 2017
Červenka, Jan
A third (33%) of people believe that for the income of their household they can buy or pay less than a year ago, 53% believe that the real income of their households is about the same as a year before, and 11% of respondents said that their real income during the last year has increased. 51% of Czech citizens consider current inflation to be acceptable, 29% of people share the opposite opinion. 44% of Czechs expect that this year they will be able to buy less goods and pay less services for the same amount of money than the last year.

SPECT regional cerebral blood flow in diferential diagnosis of dementias.
Švehlová, Dana ; Lang, Otto (advisor)
To assess the importance of testing single-photon emission computed tomography (SPECT ) of the brain in patients with cognitive disorders, a retrospective Data analysis examined patients over four years to compare the clinical diagnosis conclusions SPECT brain. Of 33 patients with clinically probable Alzheimer's disease ( AD ) had 87 % brain SPECT image of AD , half of them was present finding of mixed dementia ( MIX) . U 13 with mild cognitive impairment (MCI) were found heterogeneous patterns of brain perfusion matching mixed population of individuals with MCI and their significance can be evaluated only after a longer interval . In the next phase we test the hypothesis of hypoperfusion in the cingulate gyrus posterior patients with MCI (4 ) could be a promising marker for early detection of AD in a heterogeneous group of these patients. We performed measurements of regional perfusion in the posterior cingulate gyrus in the 10 AD patients , a 7 patients with MCI and 6 standard. Low perfusion in this field has been demonstrated in patients with AD . Keywords : 99mTc - HMPAO SPECT brain , dementia , cognitive disorders , Alzheimer's disease

Analýza invazivní schopnosti a infekčního potenciálu nově popsaných druhů borelie z komplexu \kur{Borrelia burgdorferi} sensu lato, \kur{B. americana} a \kur{B. carolinensis} na laboratoním modelu infikovaných savců
ŠOLCOVÁ, Lucie
The aim of the study was to analyze the infectious potential of the newly described species, B. americana and B. carolinensis, studied on the laboratory model mammals mice. Our goal was to analyze and compare the vectorial capacity of two different tick vectors, Amblyomma americanum and Ixodes ricinus, in acquiring and transmition of both spirochete species to the host. The results of this study confirmed that ticks A. americanum and I. ricinus are capable to maintain and transmit B. americana and B.carolinensis.We confirmed that both analysed spirochete species, B. carolinensis and B. americana, showed the potential to develop the disease in laboratory model mammal, which indirectly support the fact that both spirochete species might be concidered as the risk factors in the area where they are distributed. Our results shows that A. americanum is able to transmit both spirochete species, which increases that risk of acquiring the Lyme disease to human population in the area of distribution of A. americanum

The Migration of Labour in The Southbohemian District
PETRÁCH, Filip
My bachelor thesis deals with the analysis of the labour market, in the context of the labour mobility in the Southbohemian District. The bachelor thesis contains two parts: Theoretical part describes the labour market, its functions, segments and types of the area mobility. The author dwells in this part upon the characteristic of the chosen and monitored region, in the economical and social aspect. The second, practical part is subdivided to three chapters. These chapters include the primary research of the trends and streams in the types (3) of the area mobility, evaluation of the mobility influence, in connection with the labour market, and the prognosis of the future situation at the end. The analysis of the abovementioned trends and streams makes its observations within three major types of the area mobility: 1) The up-country migration (mobility) in Czech Republic is observed in the period 1996 {--} 2006. 2) Immigration of the foreigners in the same time period. 3) The commutation is monitored in the years 1991 and 2001. The analysis proceeds from the temporal series, where the ordinary used indicators (e. g. balance, turnover, intensity, effectivity, gross and net rate of migration) are applied. The last chapter of the practical part brings up the prognosis for the area mobility progress, in the context of labour market, or its indicators.