National Repository of Grey Literature 133 records found  1 - 10nextend  jump to record: Search took 0.01 seconds. 
Mapping the Experience of Occupational Therapists with the Entrepreneurship of Occupational Therapy: Challenges and Opportunities
Iroušková, Darina ; Jelínková, Jana (advisor) ; Nováková, Olga (referee)
OF THE DIPLOMA THESIS Name: Bc. Darina Iroušková Thesis supervisor: Mgr. Jana Jelínková Thesis consultant: PhDr. et PhDr. PaedDr. Pavel Harsa, MBA, Ph.D., Ph.D. Title: Mapping the Experience of Occupational Therapists with the Entrepreneurship of Occupational Therapy: Challenges and Opportunities. Abstract of the diploma thesis: The theoretical part of this diploma thesis deals with the elaboration of the topics of entrepreneurship with specifics arising from the fields of health care, occupational therapy, including the conditions of providing health care and the legislative support of business, knowledge about the acquisition of entrepreneurial competencies and addressing ethical and quality issues of services provided. The practical part includes qualitative analysis of in-depth interviews conducted with seven occupational therapists who have established and successfully run private practice. The aim of the research interview was to obtain descriptive information about private occupational therapists' private businesses and to map their personal experiences of entrepreneurship. This exploration results in an understanding of the unique mindset of entrepreneurial occupational therapists by identifying their motives for starting a business and subsequently uncovering the entrepreneurial...
Verification of fermentative process of grape juice
Procházková, Lenka ; Nováková, Olga (referee) ; Vránová, Dana (advisor)
This thesis deals with identification of yeasts isolated during spontaneous fermentation of grape juice. For analysis the Pinot Noir grape variety grown in the integrated vineyard was chosen. In the theoretical part of this thesis basic information about yeasts are described. Genera of yeasts that occurs during fermentation process and methods based on PCR are also described. In this thesis PCR-RFLP method was used for identification of yeasts. The amplification of the 5,8S-ITS rDNA sequence was performed by the polymerase chain reaction with use of the primers ITS1 and ITS4. The restriction analysis was performed by applying five restriction endonucleases: HaeIII, HinfI, Taq?, AluI, MseI. The amplicons were split into fragments which length and number are typical for the particular species. These fragments were identified by agarose gel electrophoresis and electrophoreograms were evaluated by BioNumerics software. Dendrograms representing genetic similarity of isolated wine yeasts were created by using UPGMA cluster analysis.
The effect of chronic cold on Ca2+-ATPase (SERCA2) in rat heart
Šeovićová, Maja ; Horníková, Daniela (advisor) ; Nováková, Olga (referee)
Acute cold exposure is a significant stressor activating heat production by shivering after the prolonged exposure cellular oxidative stress increases. Chronic exposure to cold lasting at least 2 weeks leads to the development of cold acclimatization. The main thermogenic role is taken over by non-shivering thermogenesis taking place in brown adipose tissue, which significantly increases its weight due to cold. Cardiac hypertrophy, hypertension and impaired renal function are frequently observed pathologies of acclimatization at 4-5 řC. Our laboratory recently introduced a model of mild chronic cold acclimatization at 8 řC, during which no damage to the heart or kidneys occurs and has proven cardioprotective effect on reducing infarct size. Hence, the influence of this cold acclimatization model on the other cellular and molecular processes needs to be investigated. The cardioprotective effect of cold acclimatization includes changes in β-AR signaling, activation of anti-apoptotic pathways or augmentation of the antioxidant system. The aim of this thesis was to investigate the effect of cold acclimation and subsequent reacclimation on proteins regulating Ca2+ levels in the rat heart (SERCA2 and phospholamban) and on the stimulation of regulatory proteins β-arrestin 1/2 and protein kinase PDPK1. The...
Analysis of PKCα Influence on Cancer Cell Invasion.
Szabadosová, Emília ; Brábek, Jan (advisor) ; Nováková, Olga (referee)
7 Abstract Protein kinase C alpha (PKCα) is a serine/threonine protein kinase. PKCα is an important protein regulating cell polarity, protein secretion, apoptosis, cell proliferation and differentiation and tumorogenesis. Previous research has shown a role of PKCα also in a cancer cell migration and cancer cell invasion. The aim of this study was to investigate the role of protein kinase C alpha (PKCα) played in amoeboid mode of cancer cell invasion. We showed that higher expression of PKCα resulted in mesenchymal-amoeboid transition of K2 and MDA mesenchymal cancer cell lines, which was accompanied with decreased cancer cell invasive capability in 3D collage matrix. PKCα overexpression had no effect on the cell morphology of A375m2, however, the results showed a trend in increased invasive potential of A375m2 cells. Conversely, the expression of dominant-negative PKCα resulted in amoeboid-mesenchymal transition of A375m2 cells, and it was associated with decreased invasive potential of K2 and MDA cell lines. Furthermore, a linkage between PKCα and phosphatidylinositol 3-kinase (PI3K) was tested. The results revealed that increased activity of PKCα was accompanied with decreased level of active Akt in K2 cell line. To summarize, our results suggest a probable role of PKCα in regulation of amoeboid...
Occupational therapy in the rehabilitation of patients after fracture of the distal radius and hand
Malečková, Zuzana ; Nováková, Petra (advisor) ; Nováková, Olga (referee)
BACHELOR THESIS ABSTRACT Name, Surname: Zuzana Malečková Supervisor: Mgr. Petra Novotná Consultant: Bc. Aneta Křivánková Title: Occupational therapy in the rehabilitation of patients after fracture of the distal radius and hand Abstract: This is a theoretical-practical work. The theoretical part briefly describes the anatomy and kinesiology of the upper limb with a focus on the hand and wrist, and then presents a summary of the most common fractures in this body part. The last and the longest chapter is about the possibilities of occupational therapy for patients fractures of the distal radius and hand, especially in the period after removal of fixation. Occupational therapy has a very wide application for these patients. Functional disorders of the hand and wrist, which are a frequent complication of fracture treatment, are often closely related to the limitation of self-sufficiency and have a great impact on the patient's quality of life. The aim of the practical part is chosen and verify the occupational therapy methods for people with fractures of the distal radius and hand. This section contains case reports of three patients, two of whom suffered a distal radius fracture and one with fracture of the fifth metacarpal. Each case report contains a detailed initial and discharge examination with a focus...
Driving Simulator and Its Use in the Rehabilitation of People with Acquired Brain Injury
Strubinská, Šárka ; König, Jan (advisor) ; Nováková, Olga (referee)
DIPLOMA THESIS ABSTRACT Name, surname: Bc. Šárka Strubinská Supervisor: Mgr. Jan König Consultant: Mgr. Eliška Burdová, Mgr. Bc. Jitka Bonková Sýkorová Title: Driving Simulator and Its Use in the Rehabilitation of People with Acquired Brain Injury Abstract: The diploma thesis describes the utilization of a driving simulator for manual control in the rehabilitation of individuals with acquired brain injury. The main objective of this thesis is to determine the feasibility of using a driving simulator and its potential to increase the likelihood of returning to driving by clients with acquired brain injury in the chronic stage. The first sub-objective is to investigate the influence of driving simulator training on attention and the potential to increase the likelihood of returning to driving by clients with acquired brain injury in the chronic stage. The second sub-objective is to determine whether the proposed set of tests is appropriately designed as a criterion for inclusion in the driving simulator research. The theoretical part summarizes the knowledge about acquired brain injury and its consequences, cognitive functions, impairments, car driving, and legislative regulations or possibilities for driving skills testing. Furthermore, this section provides information about rehabilitation by acquired brain...
Distance Therapy and Telerehabilitation in Occupational Therapy: Contemporary Use in Patients after Acquired Brain Injuries.
Altmanová, Šárka ; Hoidekrová, Kristýna (advisor) ; Nováková, Olga (referee)
DIPLOMOVÉ PRÁCE Jméno, příjmení: Bc. Šárka Altmanová Vedoucí práce: PhDr. Kristýna Hoidekrová, Ph.D. Title: Distance therapy and telerehabilitation in occupational therapy: contemporary use in patients after acquired brain injuries Abstract: Acquired brain injuries (ABI) are the most represented type of injuries in neurorehabilitation. In the Czech Republic, there is a shortage of outpatient occupational therapists. The involvement of telerehabilitation appears to be a possible solution to the lack of therapists. These methods are already being used with a good effect around the world. The aim of this thesis is to compare the possibilities of telerehabilitation against conventional occupational therapy in patients with ABI. A partial goal is to undertake a SWOT analysis of telerehabilitation and evaluate the communication platform eAmbulance. There are four single case studies. The patients are aged between 27-81 years (two women and two men) with different severity of right-sided hemiparesis. These patients underwent interventions of 60 minutes per week for a period of four weeks. The content of each therapy was different. Patients filled in a feedback questionnaire following each intervention. The results show that a large variation of approaches from conventional therapies can be used. The...
Executive function assessment in patients with acquired brain damage: translation and clinical use of the ‚‚Weekly Calendar Planning Activity"
Michálková, Nikol ; Krivošíková, Mária (advisor) ; Nováková, Olga (referee)
Name, Surname: Nikol Michálková Thesis supervisor: Bc. Mária Krivošíková, M.Sc. Title: Executive function assessment in patients with acquired brain damage: Translation and clinical use of the "Weekly Calendar Planning Activity" Abstract: Executive functions are absolutely essential for everyday life and when they are violated, a person is often severely limited in all areas of their life. People with a disorder of these functions tend to have problems, for example with starting an activity and planning individual steps, or are unable to complete the activity correctly and efficiently. Executive functions are localized primarily in the area of the frontal lobes and when they are damaged, an executive deficit is manifested. Clinically, the impairment of executive functions manifests itself in very diverse ways. The degree and severity of the disability depends on many factors, such as the etiology of the acquired brain damage, its location or education of the patient. The aim of this bachelor's thesis is the one-way translation of the "Weekly Calendar Planning Activity" test from English to Czech language and its subsequent verification in practice on selected patients with acquired brain damage. This is a so-called performance test that evaluates executive functions using an activity (filling in a...
System of Prevocational Assessment Centers in the Czech Republic and his Functioning in the Process of Prevocational Assessment from the Perspective of Occupational Therapist
Pudichová, Anna ; Sládková, Petra (advisor) ; Nováková, Olga (referee)
Title: System of Prevocational Assessment Centers in the Czech Republic and his functioning in the process of Prevocational Assessment from the perspective of the Occupational therapist Abstract: Prevocational assessment is a process intended for people with disabilities, during this process, the work potential of the client is evaluated for employment purposes. The applicant for this examination can be the Labor Office, the employer or the client himself. The prevocational assessment examination is attended by an interprofessional rehabilitation team, an integral part of this team are doctors, as well as non-medical professions, including an occupational therapist. The prevocational assessment examination is a very important component of the entire prevocational assessment, as it is the most time-consuming part of this examination.The examination takes place in one of thirteen specialized Prevocational Assessment centers in the Czech Republic. All centers must meet personal, substantive and material standards. Conclusions from individual examinations are presented by experts from the team at a case conference. The output of the prevocational assessment examination is a final report that contains a positive recommendation of what the client can handle or could handle. The aim of the thesis was to find out...

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4 NOVÁKOVÁ, Olga
2 Nováková, Oldřiška
3 Nováková, Olga,
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