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The objectification of therapeutical methods used for improvement of the deep stabilizng spinal system
Malátová, Renata ; Kolář, Pavel (advisor) ; Bunc, Václav (referee) ; Pavlů, Dagmar (referee) ; Marešová, Dana (referee)
5 Summary So far, no commercially used device, capable of evaluating the condition of the deep stabilizing spine system (DSSS), has appeared on the market. Therefore, a so called muscle dynamometer (SD01, SD02), has been constructed that enables to reveal a possible dysfunction of the DSSS. During a six-week-rehabilitation-course, aimed at correcting the body posture and strengthening the DSSS muscles, a statistically significant change (p<0.001) between the values of input and output measurements of the chosen group tested has been obtained. Correctness of the approach to objectify the initial state of the patient and his progress during the treatment was shown by the completed measurements. The effectiveness of therapeutical training was confirmed. Based on positive experience from SD01, a new version of muscle dynamometer, SD02, was constructed. Measurements by SD02 were to establish the condition of DSSS (frontal spine stabilization) by a lay-sit test repeatedly from the test battery UNIFITTEST 6-60 and by the diaphragm test. Measurements were conducted on 45 samples. Basic somatic measurements were performed and then measurements with the SD02 were conducted during the diaphragm test and UNIFITTEST. For comparison of the values the pairing t-test was used (normal data distribution was verified by the...
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Insulin secretion in women with polycystic ovary syndrome
Grimmichová, Tereza ; Haluzík, Martin (advisor) ; Marešová, Dana (referee) ; Rešlová, Taťána (referee)
Polycystic ovary syndrome (PCOS) is one of the most common endocrinopathies occuring in 5-10% women in their fertile years. The incidence of impaired glucose tolerance and diabetes mellitus type 2 is significantly increased in PCOS. Hyperinsulinaemia and insulin resistance are present in a relevant number of PCOS women. In our projects we therefore concentrated on various aspects of insulin secretion in PCOS women. We used different approaches and calculations, which are complementary to each other and provide a more detailed insight into possible beta cell dysfunction. Aims of our studies were 1) examine how the beta cell function is influenced by the family history of DM 2, 2) examine the insulin pulsatile secretion, 3) examine the secretion of incretins and 4) examine the prevalence of glucose intolerance and its potential prediction in PCOS women. 1) Decreased insulin sensitivity was observed only in PCOS women with the positive family history of DM 2 in comparison to healthy controls. If these women have normal glucose tolerance, they compensate the decreased insulin sensititivity by the increased insulin secretion. 2) Lean PCOS women had similar insulin pulsatile secretion patterns with the exception of broader insulin peaks in comparison to healthy controls. Insulin sensitivity was not associated...
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Adrenal function in patients with diabetes mellitus type 1 (young adults)
Šimůnková, Kateřina ; Vondra, Karel (advisor) ; Kršek, Michal (referee) ; Marešová, Dana (referee)
Background: The Addison disease of the autoimmune etiology is mostly appearing as a part of APS2 whereas the most dangerous is a combination of DM1 and an autoimmune adrenalitis. The first evidence of adrenal insufficiency in DM1 is a repetitive hypoglycaemia and lower insulin consumption. Changes in the HPA axis caused by either the activation of the immunity system during the APS2 or by the structural changes in the insulin binding proteins may present the basis for the subclinical adrenal insufficiency. The functional adrenal disorders without autoimmune adrenalitis are frequently observed in autoimmune diabetes mellitus. (...) Conclusions: A rather slow autoimmune adrenalitis progress is observed in adult patients with autoimmune endocrinopathies but rarely ending with a full adrenal destruction. The adrenal antibodies importance is still under study. Higher adrenal disorder count in DM1 patients with first manifestation around the age of 30 is presumed according to our results. Subclinical adrenal insufficiency is still very difficult to diagnose and new diagnostic ways 7 are recently being proposed. We have proven the advantages of salivary cortisol during the test as well as in daily profile. We have shown that adrenal disorders are not caused by cortisol binding peptide structure modifications in...
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Mobile Phone in the Life of a Child
Marešová, Dana ; Marádová, Eva (advisor) ; Kučírek, Jiří (referee)
This graduation thesis is about phenomenon of mobile phones and its concept in relation to the children. In the first part of thesis the attention is given to psychology, medical, economical, education aspects of the use of mobile phones by the children from its positive and negative point of view. The fundamental attention is given to its influence in educational system. The second part introduces results of the research, surveying the influence of the mobile phones on the life style of the children between 11-15 years old. The conclusion of the thesis is recommendation for the pedagogical field.
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Diagnostic options for detection of postoperative lymphoedema in patients with breast cancer
Halaška, Michael ; Marešová, Dana (advisor) ; Bunc, Václav (referee) ; Stárka, Luboslav (referee)
Lymphoedema is a severe postoperative complication after treatment of many malignancies. It is a pathological accumulation of extracellular water (ECW). Early diagnostic tool is needed. Multifrequency bioimpedance analysis (MFBIA) is a method for detection of changes in ECW. We would like to establish the methodology for detection of lymphoedema of limb in patients undergoing breast cancer surgery. We measured a control group of 60 women, 5 women with pronounced lymphoedema and a group of 37 patients undergoing a breast cancer surgery during 9 month after the surgery by MFBIA and circumferency. Characteristics of the patients were recorded. Different linear extrapolations from 1, 5, 50, 100, 200 kHz were determined to find resistance at 0 Hz for each women; ratio of R0 nondominant/ dominant and non-operated/operated limb was evaluated; Pearson correlation coefficient was used to compare correlation of the results and characteristics of the patient. Extrapolation with the lowest standard deviation was found to be 5, 50, 100 kHz. On the group of women with pronounced lymphoedema higher sensitivity was found by MFBIA compared to circumferency measurements. Stronger correlation between the volumes calculated from circumferences with weight and BMI compared to MFBIA was found. We found statistically significant...
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The Image of the Burgher from Prague Johanna Barbora Englová, Born Zimmerová through the Family correspondence in the 19 th century
MAREŠOVÁ, Dana
The thesis is entitled "The Image of the Burgher from Prague Johanna Barbora Englová, Born Zimmerová through the Family correspondence in the 19 th century" and it presents J. B. Englova´s destiny (18101874) on the basis of both correspondence and some ego-documents analysis. She was Emanuel Engl´s mother (18441907) who was an early Czech politician. Thanks to her, even the Prague civic society can be observed. The thesis is divided into five main chapters. At first, the life within the House of Habsburg monarchy in the 19 th century is described. Afterwards, the thesis is being focused on the situation in Prague, the civic society and its possibilities as for the social life. The second chapter pursues Johanna Englova´s family life. The third chapter is the crucial one it presents social connections which Johanna Barbora Englová made throughout her life and which can be observed within the well-preserved correspondence. The last chapter presents the salon, balls and the society as a part of Johanna Englova´s life. The thesis is trying to present contacts, relationships and social situation on the given example of both former and new family of Johanna Barbora Englová. The part of the thesis consists of an all round analysis of chosen sources. Moreover, the thesis reflects a social upswing of Johanna Barbora Englová and the process of becoming a part of the civic smart set in Prague. The thesis is followed by the list of sources, bibliography and online sources. The diagram, table, genealogy and the part with visual materials are listed in the annexe.
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The Commonplace Book of Lady Zimmer from 1818 to 1837
MAREŠOVÁ, Dana
This bachelor´s thesis is called "The Commonplace Book of Lady Zimmer from 1818 to 1837" and its aim is to form a critical edition accompanied by a codicological and a content description and by an overall analysis of the book as well. The work is divided into four main chapters. The first one deals with the establishment, origin and commonplace books characteristics, afterwards it is focused on the 19th century and it descends up to the 20th century. The second chapter treats the topic of a division of the girls especially from the urban environment, their access to education and destiny to get married, and the final part of this chapter solves the level of the girls´ language knowledge and their experience as readers. The third chapter contains a critical edition which is accompanied by an interior and exterior analysis of the commonplace book of lady Zimmer, these parts are followed by the used language items analysis as well as of mistakes in the entries, poetical means, and last but not least the analysis of the topic and also the art depiction. On the basis of the analysis of this book the fourth chapter emerged and its aim is to show the environment from which the owner originated, her family background and her friends. It reveals her personality step by step as a woman originated from the urban environment living her whole life in the household of a family publishing house owner. The whole work is finished with a conclusion which contains the analysis of all gained information from this very special lady commonplace book from the beginning of the 19th century. The work is accompanied by a list of used sources and literature as well as by diagrams, tables, font samples and picture part, and a family tree of Jan Jakub Ryba which shows certain relationships with the Zimmers. One of the attachments represents the lady Zimmer´s husband´s publishing activity.
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