Doctoral theses

Doctoral theses 24,242 records found  beginprevious15427 - 15436nextend  jump to record: Search took 0.01 seconds. 
Peer Review of Vocational Education and Training Schools
Michek, Stanislav ; Rýdl, Karel (advisor) ; Chvál, Martin (referee) ; Pol, Milan (referee)
TITLE: Peer Review of Vocational Education and Training Schools AUTHOR: Stanislav Michek DEPARTMENT: Department of Primary Education, Charles University in Prague SUPERVISOR: prof. PhDr. Karel Rýdl, CSc. ABSTRACT: The subject of the research of the thesis is the issue of external evaluation, particularly technical and vocational schools by partners at the same level (peer review). In the theoretical part is paid attention to concepts associated with the development of the school, the peer review is set in the context of other forms of external evaluation in education in general level and then describes the current state of the external evaluation of schools in the Czech Republic. For the empirical research was designed mixed methods design. When the research was, along with other research methods effected multiple case study - fed 4 specific stories of peer review in the Czech Republic. From the findings have been identified following supportive factors peer review: attitudes toward evaluation, condition, experience with evaluation, competency of the participants, of the interaction rated the school and peers and support peer review. At the end are suggested other possible ways of research and recommendations for educational policy. KEYWORDS: peer review, external evaluation, mixed methodology, school, teachers
The role of S100 proteins in the pathogenesis of rheumatic diseases
Andrés Cerezo, Lucie ; Šenolt, Ladislav (advisor) ; Hrnčíř, Zbyněk (referee) ; Horák, Pavel (referee)
Introduction: Recent findings and better understanding to the pathogenesis of rheumatic diseases contributed to the development of biological therapies targeting cytokines and immune cells. Several S100 proteins exert cytokine-like effects and participate in the regulation of the inflammatory process. The aim of this work was to study the role of selected S100 proteins in the activity and in the pathogenesis of the rheumatic diseases. Results: Our data show for the first time an association of S100A4 proteinwith RA disease activity and decrease of the bioactive form, but not the total amount of S100A4, after aplication of tumour necrosis factor (TNF) blocking biologic therapy in patients with RA. We demonstrated that in vitro S100A4 acts as a potent pro-inflammatory mediator inducing production of TNFα, interleukin (IL)-1β and IL-6 in PBMCs via Toll-like receptor 4 (TLR-4), transcription factor NFκB and tyrosine kinases erk1/2 and p38. Moreover, S100A4 can play an important role in the pathogenesis of inflammatory myopathies. S100A4 is present in the inflammatory infiltrate of the affected muscles and in the regenerating muscles and may act as a cytokine-like factor indirectly promoting muscle fiber damage by stimulating mononuclear cells to increase the synthesis of pro-inflammatory cytokines. We...
Topophilia and Escapism: W.H.Auden's Interwar Poetics of Place (1927-1938)
Vít, Ladislav ; Mánek, Bohuslav (advisor) ; Sukdolová, Alice (referee) ; Franková, Milada (referee)
This work focuses on Wystan Hugh Auden's (1907-1973) early poetry (1927-1938) and analyzes its engagement with places, landscapes and local cultures. The scope is limited to the interwar years, when Auden started to write poetry, entered the literary stage and formed his ethical stances, poetics and a personal voice within one of the most socially arduous and aesthetically innovative periods of recent history. This turns his 1920s and 1930s work into a fertile ground for research, which is evidenced by the large body of extant criticism scrutinizing the technical aspects of Auden's interwar poetry as well as its reflection of the poet's affinity with Marxism and the politically conscious intelligentsia of his generation. While sharing the same historical focus, this dissertation diverges from existing scholarship and traces the character of Auden's imaginative dynamic, which renders an inscription of the physical world into art. Auden was highly emotionally and intellectually responsive to particular places, environmental types, human spatial experience and their embedment in arts. This work examines his engagement with Alston Moor in the Northern Pennines, Iceland and England. In his prose, the former two are constructed as sacred places and asylums for his imaginative and physical escapism. The...
Vojvodovo Sketches
Jakoubek, Marek ; Horský, Jan (advisor) ; Moravcová, Mirjam (referee) ; Penčev, Vladimir (referee)
The dissertation "Vojvodovo Sketches" thesis consists of an introduction and further of published texts related to Vojvodovo. Vojvodovo, a Czech village in north-western Bulgaria founded in 1900 by about twenty Czech evangelical families from the village of Svatá Helena in what is today the Romanian part of Banat, which they left because of religious disputes and a shortage of land. Although Bulgaria engaged in several armed conflicts in the first decades of the twentieth century, the village flourished economically and the population rose steadily during that period. Eventually, however, its economic prosperity, based almost exclusively on agriculture, was curtailed by a land shortage. As a result, some villagers emigrated to Argentina in 1928. By 1934/5 the village was again overcrowded and suffering serious land shortage. This time some of its inhabitants moved to the Turkish village of Belinci in north-eastern Bulgaria (Isperich region). The history of Czech settlement in Vojvodovo, as well as Belinci, effectively ends in 1949-1950, when the overwhelming majority of their Czech inhabitants left as a part of post-war migratory processes organized under inter-state agreements and resettled in several villages in the South Moravia region of the Czechoslovak Republic. Vojvodovans were renowned for their...
Fundamental Painting: Birth, Characteristics, Formal Roots and Significance
Rajlich, Claudia ; Lahoda, Vojtěch (advisor) ; Wittlich, Petr (referee) ; Valoch, Jiří (referee)
Title: Fundamental Painting Author: Claudia Rajlich Department: Institute of Art History Supervisor: Prof. PhDr. Vojtěch Lahoda, CSc. Abstract: This dissertation wishes to define fundamental painting - a term which was coined and a current which was defined by the Stedelijk Museum in Amsterdam in the form of a show of 18 artists of different nationalities in 1975. Like the show, it wishes to give a clear view of a specific new kind of painting of the 1970s, which is "a reflection on the foundations of painting."1 The core of Fundamental Painting is formed by the four painters of American Minimal Art and the show based on a text concerning their work (upon which innumerable texts have been written since). This dissertation focuses on the European part of this "common mentality" as the curators call it, which remains unresearched until today. Its scope is to define: What was it, where did it come from and was it at all? The research is limited to artists in the show (although we conclude that a few should be replaced by others), historical evidence concerning new painting in the 1970s, the critical analysis of texts, artists statements and, above all, the undeniable documentation in the form of the body of works themselves. The existence of Fundamental Painting is proven, its characteristics determined in...
Neuronavigation of RMTS based on brain functional imaging in clinical aplication in auditory hallucinations
Klírová, Monika ; Horáček, Jiří (advisor) ; Papežová, Hana (referee) ; Rektorová, Irena (referee)
NEURONAVIGATION OF rTMS BASED ON BRAIN FUNCTIONAL IMAGING IN CLINICAL APPLICATION IN AUDITORY HALLUCINATIONS Monika Klírová Summary Transcranial magnetic stimulation (TMS) represents a noninvasive method used in diagnostics of neurological disorders and physiological research of sensoric, motor and cognitive function and intracortical relations. This method has found its leading position also in the treatment of neuropsychiatric disorders. TMS is based on the administration of short pulses of a strong magnetic field, which induces secondary electric currents in a limited volume of cerebral cortex. Therapeutic modification utilizes a repetitive TMS (rTMS) in which the magnetic coil generate a series of pulses of different frequencies. Low-frequency rTMS (LF-rTMS) of the left temporo-parietal cortex (LTPC) has been proposed as a useful therapeutic method for auditory hallucinations (AHs). Majority of rTMS studies use "standard" coil positioning, which is often not fully corresponding to cortical area(s) of maximal functional changes. Stereotactic neuronavigation enables the magnetic coil to be targeted according to the individual parameters obtained from neuroimaging. Individualized rTMS neuronavigated according to positron emission tomography (18 FDG PET) allows us to focus the coil explicitly on a given...
Music collections of the Brothers Hospitallers in the Bohemia Lands
Freemanová, Michaela ; Gabrielová, Jarmila (advisor) ; Sehnal, Jiří (referee) ; Perutková, Jana (referee)
The 'provincia germanica' of the Order of the Brothers Hospitallers was probably founded in 1616. In the early 1770s it covered almost the whole of Central Europe. Today's Bohemian province consists of eight monasteries (Prague, Nové Město nad Metují, Kuks, Brno, Prostějov, Valtice, Letovice and Vizovice). This book deals with their history, their music life and their surviving music collections from Prague, Nové Město nad Metují, Kuks (the Kuks collection catalogue was published independently in 1998), Prostějov, Brno and Valtice (the Letovice and Vizovice collections are not extant). They are quite a rarity: it seems that, apart from the small collections in Graz and Vienna, and the until now inaccessible Wroclaw (Breslau) collection, no other such collections survived anywhere else in the former Austro-Hungarian Empire. Apart from Kuks, most of the Czech and Moravian Order music collections are fragmentary. Fragmentary also are the Order documents. Even so it is possible to follow the rise and fall of the music activities of the Brothers Hospitallers, whose original and principal mission was to care for the helpless, aged and the sick. Music became integral part of the Order members' general education inside the "provincia germanica" since 1718; the musicians named in the catalogues of the Order...
Changes of systolic blood pressure figures in dependance on measuring point, body position and the level of physical load among girls from 11 to 13 years
Pavlů, Regina ; Bartůňková, Staša (advisor) ; Kohlíková, Eva (referee) ; Velemínský, Miloš (referee)
Thesis is a pilot study to get reference figures for evaluation of relevancy of hemodynamic development disorders of coartation of the aorta. 18 healthy girls aged from 11 to 13 were tested. In total 450 measurements were carried out and 2700 figures were measured within 1 year in 5 positions. Blood pressure was measured on arteria brachialis and femoralis, supplemented by electric impedance technology on lower limb. The following positions were measured: standstill lying down on a bed, stand after passive verticality up to 66 degrees, standstill seat on a bicycle ergometer and load of 1W/kg and 2W/kg of body weight for 3 minutes. This thesis confirmed the differences in circulation reactions. The systolic pressure gradient among healthy population was lower than among patients with coarctation of aorta and during the physical load was decreasing. The results are important for diagnostics examinations of evolutionary defects. Keyvords: BMI, coarctation of aorta, systolic blood pressure, pressure gradient, load testing
Description quadrupedal locomotion diagonal pattern in specific sport activity (rope climbing, walking, pull-up)
Bačáková, Radka ; Kračmar, Bronislav (advisor) ; Kučera, Miroslav (referee) ; Zounková, Irena (referee)
Tittle: Description quadrupedal locomotion diagonal pattern in specific sport activity (rope climbing, walking, pull-up) Aim of work: The aim is to find a description kvadrupedal locomotion diagonal pattern with rope climbing and its motion pattern compared with the motion pattern of walking and pull-up. Methods: This work is descriptively-association study with quantitative and qualitative analysis. The dates were measured by surface electromyography and 2-D video-analysis. Results: Alternating activation of upper extremities (rope climbing without the lower extremities), we proved that the movement supporting lower extremities is quadruped locomotion diagonal pattern. Symmetric work of upper extremities (pull-up) is not in response at lower extremities quadruped locomotion diagonal pattern. Key words: Electromyography (EMG), quadruped, diagonal pattern, rope climbing, pull-up, walking
The Right of Self-Defense in Current International Law
Kittrich, Jan ; Hýbnerová, Stanislava (advisor) ; Ondřej, Jan (referee) ; Beránek, Milan (referee)
The Right of Self-Defense in Current International Law The dissertation thesis is devoted to one of the key issues of current international law - the right to self-defense. The work is divided into six chapters including introduction and conclusion. After an introductory chapter describing the historical development of the use of force in international relations, it deals with classical self-defense in the context of customary law and contractual setting in the U.N. Charter. The main attention is devoted to the analysis of particularly controversial concepts, such as for example armed attack, with the explanation based on the International Court of Justice case law and doctrinal interpretation. In this context, substantial part of this chapter is devoted to the issue of indirect use of force. In this respect, the judgment of the International Court of Justice in case of Nicaragua is discussed in detail. The thesis also explores the relatively new concept in international law - the cyber-attack. The next chapter deals with preventive self-defense. The thesis analyzes in detail the doctrinal approaches to prevention, focusing on their main arguments. The two main theories - traditional and restrictive - are subject to thorough analysis. This chapter is also devoted in detail on the historical...

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