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The effect of specific dietary intervention on inflammatory activation of innate immunity in patients with stabilized celiac disease
Selková, Katarína ; Daňková, Pavlína (advisor) ; Černá, Marie (referee)
Introduction: Celiac disease is a complex autoimmune disease induced in genetically predisposed individuals after ingestion of cereals containing gluten. Monocytes, as the main effector cells of innate immunity, play a non-negligible role in the development of the immune response in response to pathogenic and foreign agents as well as in the pathogenesis of celiac disease. The only effective treatment for celiac disease is strict and lifelong adherence to a gluten-free diet, while dietary choices are of key importance in the regulation of this disease. Oats have emerged as a controversial but nutritionally rich option to supplement a gluten-free diet with a source rich in fiber, micro- and macronutrients. Therefore, in this thesis, we focused on how the innate immune system, specifically monocytes, interact with the avenin peptides of a selected gluten-free oat cultivar and whether an immune reaction detectable at the molecular level occurs in response to its consumption. Materials and methods: 39 patients with stabilized celiac disease were included in the study, who consumed 50 g of raw oatmeal of the selected cultivar daily for 14 days. CD14+ monocytes were isolated from whole blood before the start of the study and after its completion using immunomagnetic separation, in which TLR2, TLR4, TNFα,...
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Art therapy as a support tool for high school art students
ČERNÁ, Magdalena
This bachelor thesis introduces the possibilities of incorporating art therapy as a supportive method for secondary art school students. The theoretical part deals with the definition of the term adolescence, the issue of physical and psychological changes during high school and the most common behavioural disorders associated with this period. It also briefly describes the characteristic principles of art therapy. The practical part is based on the author's work with selected pupils. Case studies of individual respondents with whom the author has worked during several sessions are described. The characteristics of the art expression of the pupils of the secondary art school are also presented. The aim of this bachelor thesis is to outline the possibilities of using art therapy in secondary art schools and the effects it has on pupils.
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Vliv typu ustájení na reakci koní na nový předmět
ČERNÁ, Michaela
Horses are highly sensitive animals that react intensely to new objects or environments that are unfamiliar to them. This rapid response stems from their natural role as prey in the wild, which is why they have instinctive fright reactions. The aim of this thesis was to develop a methodology for testing horses' reactions to new objects based on available literature and to evaluate the influence of factors such as type of housing and the age of the horses. The testing included 18 horses aged between 1 and 22 years from three types of housing (active stable, box housing, and pasture housing). Fear tests lasting 5 minutes monitored reactions to objects such as colored ribbons and a blue tarp. The mattress crossing test lasted a maximum of 10 minutes. In both fear tests with colored ribbons and the tarp, horses from box housing showed greater signs of nervousness. Statistically, they spent more time moving compared to horses from the active stable (an average of 10,5 seconds more for colored ribbons and 4,8 seconds more for the tarp). Conversely, individuals from active stables consistently spent more time exploring (an average of 17 seconds more for colored ribbons and 25 seconds more for the tarp). In the fear test of mattress crossing, no difference was demonstrated between the horses from the observed types of housing (p-value = 0,679 > 0,05). A correlation analysis assessed the influence of age on the duration of various behavioral displays when encountering a new object. In the case of the tarp and colored ribbons test, older horses spent less time standing, exploring, galloping, and inside the designated circle compared to younger individuals. Conversely, older horses walked more and spent more time on the tarp and eating compared to younger ones. Older horses needed more time to overcome the mattress compared to younger ones (r = 0,12). The significance of the enriched environment, presented in this work by the active stable, is in the milder reaction of horses to new objects and the reduced risk during human contact.
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Influence of input material on technology and production of deep drawn product
Černá, Monika ; Peterková, Eva (referee) ; Šulák, Ivo (advisor)
This bachelor thesis was elaborated in cooperation with company ITW Pronovia, s.r.o within the scope of the bachelor degree and presents an assessment of the effect of material properties and manufacturing technology of a deep-drawn product. In this work the mechanical and technological tests were carried out on the supplied material HT179. This material is further processed into a cartridge for an airbag deployment. During production many defects occurred, especially after cutting out the holes of deep-drawn product. The company established these defects as material property. Therefore it is necessary to evaluate the characteristics of different material sets.
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Resource assessment of environmental risks in industrial enterprise
Černá, Monika ; Kotek, Luboš (referee) ; Krbalová, Maria (advisor)
This diploma thesis is focused on evaluating the sources of environmental risks in the safety domain of the Honeywell Aerospace Olomouc company. First part of the diploma thesis is theoretical and serves as an entry to problematics of severe accidents prevention, risks identification and assessment. In the next part all the chemical substances stored in this international industrial company are valorised, the substances most dangerous to the environment are identified and certain precautions to prevent serious accidents are suggested according to valid legislation and recommended methods of the Ministry of the Environment.
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Deposit Products of Banks and Non-Bank Savings Institutions
Ulman, Tomáš ; Černá, Martina (referee) ; Ptáček, Roman (advisor)
This thesis is focuses on the comparison and selection of the most appropriate term deposits for the company Hamé, s.r.o. of bank and non-bank savings institutions operating on the czech market. The analysis and subsequent comparison of selected term deposit is made on the basis of the ranking method and subsequently using the scoring. From results of the analysis and the comparison are then selected and recommended the best combination term deposits for the management of the company.
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Proposal for alternative financing of the reconstruction of the square in Třebíč
Hykolli, Nikolas ; Černá, Marie (referee) ; Vaňková, Lucie (advisor)
The diploma thesis deals with the proposal of a possible way of financing the reconstruction of Charles Square in Třebíč and choosing the optimal variant. The theoretical part summarizes all important concepts related to the theme of the diploma thesis. These include public administration in the Czech Republic, central and local budget systems, selection procedures and funding sources. In the practical part are found the ways of financing the urban investment, both own and foreign. These may include credits and grant titles.
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Deposit Products of Banks and Non-Bank Savings Institutions
Ulman, Tomáš ; Černá, Martina (referee) ; Ptáček, Roman (advisor)
This thesis is focuses on the comparison and selection of the most appropriate term deposits for the company Hamé, s.r.o. of bank and non-bank savings institutions operating on the czech market. The analysis and subsequent comparison of selected term deposit is made on the basis of the ranking method and subsequently using the scoring. From results of the analysis and the comparison are then selected and recommended the best combination term deposits for the management of the company.
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