Original title: Oxidative Potential of PM1 and PM2.5 Urban Aerosol and Associated Elements in Three Simulated Lung Fluids
Authors: Cigánková, Hana ; Mikuška, Pavel ; Hegrová, J.
Document type: Papers
Conference/Event: výroční konference České aerosolové společnosti /21./, Kutná hora (CZ), 20221003
Year: 2022
Language: eng
Abstract: Mass concentration of particulate matter (PM) has been used in several epidemiologic studies as an indicatior conenecting PM concentrations with human health effects (Ostro, 1993). However, mass concentration of PM doesn´t consider the different compositions and toxicological effects of its components. Majority of PM mass constitutes low-toxicity components, while minority of trace components may have high toxicological activity (Tonne, 2012). Oxidative potential (OP), defined as the ability of PM to induce oxidative stress, is in recent years recognized as one of the main biological mechanisms considered to be contributing to negative impacts from air pollution exposure. Oxidative stress is caused through the capability of PM to generate reactive oxygen species (ROS) within the lung, which leads to pro-inflammatory responses that can ultimately results in cell apoptosis (Borlaza, 2021).
Keywords: aerosol; elements; oxidative potential
Project no.: GA20-02203S (CEP)
Funding provider: GA ČR
Host item entry: Sborník 21. výroční konference České aerosolové společnosti, ISBN 978-80-908653-0-3
Note: Související webová stránka: https://hdl.handle.net/11104/0334535

Institution: Institute of Analytical Chemistry AS ČR (web)
Document availability information: Fulltext is available in the digital repository of the Academy of Sciences.
Original record: https://hdl.handle.net/11104/0334535

Permalink: http://www.nusl.cz/ntk/nusl-510670


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