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Interaction between TiAl melt and coated oxide refractories
Dočekalová, Kateřina ; Dlouhý, Antonín ; Zemčík, L. ; Fiala, J.
The present study focuses on reactions between ceramic crucibles and molten TiAl intermetallics. Coating strategies are investigated that exhibit a potential in slowing down the decomposition of the crucible wall. Uncoated crucibles (system TiAl melt - Al2O3 crucible) and crucibles with the coat (system TiAl melt - CaO coat - Al2O3 crucible) were used in melting and casting experiments. The reference state of the coated crucible before the melting trial was also investigated. Results of the SEM, EDAX and X-ray diffraction analysis contributed to the identification of the reaction zone and its chemical composition. The melt contamination with oxide inclusions results from the erosion process in which individual components of the melt diffuse along grain boundaries of the refractory and activate chemical reactions that decompose the crucible wall. Assessment of thermodynamic parameters associated with the chemical reactions helped in identifying the nature of the erosion process.
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Gender Selection as a Topic of Bioethics
Hendlová, Tereza ; Kolářová, Kateřina (advisor) ; Kiczková, Zuzana (referee)
My thesis focuses on the topic of gender selection (deliberate determination of the child's gender which is now possible thanks to recent developments in reproductive medicine) from the perspective of biomedical ethics. The main question is whether the practise of gender selection complies with the 4 basic principles of bioethics against which all medical action should be assessed (principle of autonomy, non-maleficence, beneficence and justice). In the thesis, I distinguish between two main types of gender selection: gender selection for medical and non-medical reasons. The main focus is put on the second type, which is more ethically disputable, as it is not as directly related to the child's health and well-being as the first type. Gender selection for non-medical reasons is practiced in the context of multiple interactions of social, political, economic and other factors that all inform parental choices. One of the very influential factors is the medical discourse. For the purpose of complex contextualisation of gender selection for non-medical reasons, the concept of procreative liberty (introduced by J.A. Robertson) and feminist critiques of reproductive choices are presented. My main argument is that gender selection for non-medical reasons should not be legal and available as it has a high potential...
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Contacts betweeen family and school on elementary school
Lívancová, Šárka ; Hadj - Moussová, Zuzana (advisor) ; Viktorová, Ida (referee)
Diploma thesis discusses the communication between family and teachers, especially the specific aspects of this interaction considering small schools. The communication between parents and teachers is one of the important parts of coordination of parents and school. Communication can be divided into direct, represented by f a c e - t o - f a ce contact between parents and teachers, and indirect, which comprise telephone conversation and other messages delivered by the pupils. This t h e s i s focuses on the direct type of communication. It aims to describe s p e c i f i c forms of direct communication in context of s p e c i f i c traits of r e l a t ed environment. We assume, that the village environment, which is common for small schools, doesn't suffer of anonymity of large cities, and that people in this environment generally have closer contacts with each other. Small schools are schools for 6 to 11 years old, o f f e r i n g only the primary level of education, for which the higher rate of p a r e n t - t e a c h e r i n t e r a c t i o n is typical. In these small schools, the primary education has the p o s s i b i l i t y to preserve i t ' s autonomy, and it i s n ' t influenced by the secondary level education, which appears to be dominant, when the both levels are combined. Last but not least...
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Abstract Book URSI International Symposium Endogenous Physical Fields in Biology
Pokorný, Jiří
Book of Abstracts contains 65 abstracts of papers whose majority was presented at the symposium "Endogenous Physical Field in Biology" whose program was focused mainly on: a/ Generation of the endogenous electromagnetic filed by cellular and subcellular protein structures /e.g.microtubules/, b/ Biophysical problems of interaction of biological systems with exogenous electromagnetic fields. Some new methods used in photodynamic and hyperthermic therapy of malignant tumors are described too.
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Study of plasma-solid interaction at medium pressures
Roučka, Štěpán ; Hrach, Rudolf (advisor) ; Novotný, Dušan (referee)
The thesis is aimed at particle simulation of plasma at medium pressures. Main results concern modelling of collisions in particle-in-cell algorithm. Dierent methods of modelling of collisions are discussed and their accuracy and eciency are investigated. Furthermore a new modication of particle-in-cell algorithm for modelling at medium pressures was proposed. Numerical benchmarks in the nal chapter show advantages of the new algorithm.
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Analysing company's behaviour and communication on social networks
Němec, Milan ; Molnár, Zdeněk (advisor) ; Jelínek, Ivan (referee)
This thesis focuses on measuring company´s communication and behaviour on social networks. To capture the interaction between the company and its users the thesis uses web analytics tools. Therefore, the main objective of the thesis is analysis of these tools. To achieve this goal, the thesis characterizes social networks and their marketing opportunities for business promotion. Thanks to this, needs of using these tools is identified. The needs are: competitive analysis, optimizing communication, measuring achievement of objectives or detection competitive viral content. Research questions were determined and then analysis tools found answers to research questions. It was found that the tools provide various views of data and create a complete system for measuring and analysing behaviour and communication companies on social networks. The results were validated in a case study focused on the Facebook profile of the University of Economics in Prague. The study analysed the interaction profile of the school and its users and compared with others schools. In the results the analysis tools are validated and it is designed recommendation for improve engagement. This thesis revealed strengths and weaknesses of tools for measuring company´s communication and behaviour on social networks. It was found that these tools have wide range of use. They can be used for understanding the company's profile, its users, for purposes of competitive analysis, monitor corporate goals and optimize communications on social networks.
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Dynamic behavior od rotor dynamics stystem vibrating in a liquid
Chlud, Michal ; Pochylý, František (referee) ; Malenovský, Eduard (advisor)
This thesis deals with dynamic behavior of swirl turbine vibrating in a liquid. Primarily is studied decrease of natural frequencies of rotor due the interaction with fluid environment, namely for different levels of submerged rotor in fluid. After that follows the detection of natural frequencies of swirl turbine in operating speed. The problem is solved by computational modeling in ANSYS system. For this solution is used acoustic elements method. The results are compared with experiment.
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The endocrine function of adipose tissue and its importance for initiation and development of insulin resistance and diabetes
Haluzík, Michal ; Schreiber, Vratislav (advisor) ; Marešová, Dana (referee) ; Šeda, Ondřej (referee)
Endocrine production of adipose tissue is a very complex process affected by numerous endogenous and exogenous stimuli. Peroxisome proliferator-activated receptors-alpha (PPAR-) are important modulators of metabolic processes which can also affect endocrine function of adipose tissue. Recently, numerous novel factors produced by adipose tissue with important metabolic effects were identified. Some of them can directly bind PPAR receptors. One of the examples of these factors is fatty acid binding protein 4 (FABP4) which can directly bind PPAR receptors and indirectly modify its activation by changing availability of endogenous PPAR ligands -free fatty acids. We hypothesized that the mechanism of action of PPAR receptors to metabolic processes may partially lie in their complex interaction with adipose tissue-derived hormones. The unraveling of these interactions may have important consequences in finding approaches to treat patients with type 2 diabetes mellitus. (...) In summary, our data show an important role for the interplay of PPAR activation and endocrine function of adipose tissue in metabolic regulations which may have important clinical consequences.
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Interaction of apoprotein with heme side chains: A comparison of cytochromes P450 and NO-synthases
Fastová, Dagmar ; Hudeček, Jiří (advisor) ; Šulc, Miroslav (referee)
Cytochromes P450 and NO-synthases are two classes of heme-thiolate proteins, participating in catalysis of important biochemical reactions. In this work we analysed and compared both enzyme groups from the viewpoint of torsional angles of vinyl side chains of heme in positions 2 and 4. We used the Yasara programme to analyse the available crystalographic data. Whereas the torsional angle distributions for both vinyl groups in NO-synthases are pointing to a rather "conservative" conformations of both vinyls (between -30ř and 90ř for position 2, -150ř to 120ř for position 4, resp.) with little differences for individual forms of these enzymes, the mammalian cytochromes P450 display considerable differences between different families. In accordance with previous analyses is the distribution of torsional angles of 2-vinyls in most cases narrower (-120ř to 150ř) compared to 4-vinyls, which display more conformational flexibility (with torsional angles between -30ř and 180ř). In the second part of the Thesis we analysed the interaction of cytochrome P450 with its reaction partner, cytochrome P450 reductase. On the basis of crystalographic data we tried to prove, if the spatial positions of basic aminoacids, corresponding in the primary structure of various mammalian forms the those in the isoform 2B4...
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