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Identification of risks related to industrial furnaces - electric arc furnaces
Krejčí, Lukáš ; Rozehnalová, Jana (referee) ; Kotek, Luboš (advisor)
Main goal of presented bachelors thesis is identification of hazards associated with operation of electric arc furnaces. But at first it is necessary to become acquainted with the device and to understand its function. Therefore description of construction with emphasis on electrical circuit, overview of few selected industrial disasters and legislative requirements for safe operation of the furnaces form starting position for hazard identification which is carried out according to the procedure of the standard ISO 12100 in the last chapter of this thesis.
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Implementation of selected parts of the ČSN EN ISO/IEC standard 17025:2018 in the calibration laboratory
Krejčí, Lukáš ; Jankových, Róbert (referee) ; Šrámek, Jan (advisor)
In this diploma thesis comparison of the current state against the requirements of the standard ČSN EN ISO/IEC 17025: 2018 is made at first. The comparison is followed by proposals for the creation of the missing documents which will become part of the controlled documentation of the selected calibration laboratory in the future and will be used to obtain accreditation. These documents are focused specifically on process management of the calibration laboratory and the procedure for determining uncertainty of measurement in calibration. Proposals are created in a way to match the specifications of standard ČSN EN ISO/IEC 17025: 2018. In the conclusion chapter of this thesis there are recommendations for calibration laboratory which should be considered before applying for accreditation.
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Effects of allopregnanolon on motor functions of young laboratory rat.
Krejčí, Lukáš ; Mareš, Pavel (advisor) ; Valeš, Karel (referee)
Allopregnanolone is a typical representative of neurosteroids. It can be formed by de novo synthesis directly in the CNS or as a metabolite of progesterone. It is an allosteric modulator of GABAA receptors, due to which it has anxiolytic, sedative and anticonvulsant effects. This work investigates the effect of allopregnanolone (ALLO) on the locomotor skills of laboratory rat pups. The results will serve as a reference study for the work of Tereza Košťálová (2020), who investigated the newly discovered neuroactive steroid pregnanolone pyroglutamate (PPG). This exogenous steroid, synthesized at the Institute of Organic Chemistry and Biochemistry of the Academy of Sciences of the Czech Republic (IOCB PRAGUE), offers potential use in the treatment of epilepsy. Our goal was to perform the same battery of motor tests after the application of allopregnanolone as a comparison, to what extent and in what way these two substances acutely affect the motor performance of the rat pup. The theoretical part of the thesis describes the physiological mechanisms of neurosteroids in the human body and their potential in the treatment of serious diseases, especially epilepsy. Next, the ontogenetic development of the rat's motor skills is described and compared to humans. The methodology describes the selection and...
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Comparison of cross-country racing skis chute
Krejčí, Lukáš ; Gnad, Tomáš (advisor) ; Louka, Oto (referee)
3 Abstract: Title: Comparison of cross-country racing skis chute Objectives: The aim is to compare cross-country racing skis chute. Methods: Comparison to 23 pairs of cross-country racing skis for skating from different manufacturers, in which it is assessed on the basis of the resulting chute times test section. Results: The evaluated results of measurement and testing cross-country racing skis and brands showed that currently the fastest cross-country skis for skating skis are brand Fischer. Like other brands following companies: Madshus, Salomon, Rossignol, Atomic and Sporten. Keywords: Cross-country skis, construction and materials of cross-country skis, cross-country skis chute. .
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Identification of risks related to industrial furnaces - electric arc furnaces
Krejčí, Lukáš ; Rozehnalová, Jana (referee) ; Kotek, Luboš (advisor)
Main goal of presented bachelors thesis is identification of hazards associated with operation of electric arc furnaces. But at first it is necessary to become acquainted with the device and to understand its function. Therefore description of construction with emphasis on electrical circuit, overview of few selected industrial disasters and legislative requirements for safe operation of the furnaces form starting position for hazard identification which is carried out according to the procedure of the standard ISO 12100 in the last chapter of this thesis.
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Comparison of cross-country racing skis chute
Krejčí, Lukáš ; Gnad, Tomáš (advisor) ; Louka, Oto (referee)
3 Abstract: Title: Comparison of cross-country racing skis chute Objectives: The aim is to compare cross-country racing skis chute. Methods: Comparison to 23 pairs of cross-country racing skis for skating from different manufacturers, in which it is assessed on the basis of the resulting chute times test section. Results: The evaluated results of measurement and testing cross-country racing skis and brands showed that currently the fastest cross-country skis for skating skis are brand Fischer. Like other brands following companies: Madshus, Salomon, Rossignol, Atomic and Sporten. Keywords: Cross-country skis, construction and materials of cross-country skis, cross-country skis chute. .
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