| |
| |
| |
|
Analýza samčí sterility způsobené T(16,17)43H chromosomální translokací
Čapková, Jana ; Homolka, David ; Ivánek, Robert ; Jansa, Petr ; Forejt, Jiří
Heterozygosity for certain mouse and human chromosomal rearrangements is characterized by male-limited sterility. Our model of a male-sterile chromosomal rearrangement represents mouse T(16;17)43H (T43) chromosomal translocation. The effect of the T43H translocation on spermatogenesis was studied. We analyzed meiosis in B10.T43/+ heterozygous male mice and we have obtained direct evidence on the transcriptional silencing of unsynapsed autosomal chromatin of the translocation quadrivalent and the subsequent failure of the X chromosome transcriptional inactivation at the mid-late pachytene of spermatogenesis.
|
|
Microscopy 2008
Hozák, Pavel
Two-day conference responding to novel trends in light and electron microscopy and their impact on researchers in the Czech Republic and Slovakia. Contributions were presented in biomedical as well as physics and material science fields. The Conference was held in a sports area in the heart of the Czech-Moravian Heights and was closed by an opulent rout with wine degustation.
|
| |
|
Regulace syntézy ribozomů v bakteriích
Krásný, Libor
Rapidly growing bacteria need a high number of ribosomes to satisly the cells need for increased translation. Starving bacteria need a low number of ribosomes to limit energy expenditure.The number of ribosomes is regulated at the level of ribosomal RNA (rRNA) transcription.
|
|
Původ proteinů kančí semenné plazmy
Maňásková, Pavla ; Kyselová, Vendula ; Tichá, M. ; Jonáková, Věra
Spermadhesins were detected with their antibodies in boar epididymal fluid, but DQH and beta-microseminoprotein were not. Indirect immunofluorescence technique was employed to determine the distribution of seminal plasma proteins on tissue sections of the reproductive organs. The mRNA of the DQH was found only in seminal vesicles, not in the epididymis, and the mRNA of beta-MSP in testis, seminal vesiclas and prostate.
|
| |