|
Muskarinové receptory v regulaci mechanizmů vaskulární perfúze u potkanů
Soukup, Ondřej ; Tilšer, Ivan (advisor) ; Jun, Daniel (referee)
Muscarinic receptors in the regulation of vascular perfusion mechanisms in the rat and sheep salivary glands Author: Ondřej Soukup Supervisor: Gunnar Tobin, Sahgrenska Academy,Goteborg University, Sweden Formal supervisor: Ivan Tilšer, Faculty of Pharmacy, Charles University, Czech Republic This study constists of the functional experiments, the assesment of VIP in plasma and the immunohistochemistry. Functional experiments include investigation of muscarinic receptors subtypes, their occurence and function in the rat carotid artery and jugular vein using tissue bath and muscarinic receptors agonist (carbachol) and antagonists ( pirenzepine, methoctramine, 4-DAMP). Assesment of VIP was done in the sheep plasma samples collected during 8 Hz stimulation of chorda lingual using ELISA. Immunohistochemistry of rat carotid artery and jugular vein was done using specific muscarinic antibodies and evaluated udner the fluorescence microscope. Statistical significance was determined by Student's t-test for paired data. ANOVA test in cases of multiple comparisons and post-hoc test according to Bonferoni were applied. P-values of 0.05 or less were regarded as statistically significant. The results show that muscarinic receptors have direct and indirect effect on vessels affecting the blood flow over the...
|
|
China's economic development in the 21st century: problems and perspectives
Flídr, Jan ; Jiránková, Martina (advisor) ; Hnát, Pavel (referee)
This paper focuses on China in the new century and actual problems which chinese economy faces. For better understanding of contemporary growth is this paper concerned with important history moments of chinese history. The actual situation of chinese economy is analysed with rate of GDP growth,development of international trade and foreign direct investments. The main part of this paper is focused on actual problems of chinese economy. Especially on chinese export-oriented economy, bad condition of banking sector, decreasing quality of environment, high consumption of resources and difference between chinese regions. Last part of this work is about the influence of the crisis which has started in 2008 and has great importance in actual development of chinese economy.
|
|
Origami as a Learning Environment in Mathematics Education
Boháčová, Jana ; Vondrová, Naďa (referee) ; Roubíček, Filip (advisor)
The thesis deals with origami as a learning environment in mathematics education. The two main aims of the thesis are to show the possibilities of using origami in various areas of mathematics teaching and learning, especially in synthetic geometry and calculations in geometry, and to suggest specific origami-based activities for secondary education. First, origami is introduced in its historical context and its geometrical axioms are described. Further, advantages and difficulties of using origami in mathematics education are discussed, with respect to the type and level of school. The fundamental part of the thesis consists of description and didactical analysis of tasks based on folding of an equilateral triangle and various polyhedra. Some of these tasks are adapted from other resources, some were designed by the author. Based on direct experience with employing origami-based tasks in different classrooms, methodological recommendations are added to the individual analyses, facilitating the practical usage of the thesis.
|
|
Business plan
Kubíková, Dagmar ; Scholleová, Hana (advisor) ; Jiráčková, Eva (referee)
The aim of the dissertation is create the clear directions for setting up of the business plan and to create also the real business plan of saving bank. This dissertation consists of two main parts. The theoretical part contains the needed resources for the corect design of business plan and in the practical part are those principles applied to the project.
|
|
The Application of Marketing Management in a Chosen Company
Jirák, Stanislav ; Ezrová, Hana (advisor) ; Přibyl, Jaroslav (referee)
Jirák, S.: Dissertation. Jindřichův Hradec : The University of Economics, Prague, Faculty of Management in Jindřichův Hradec 2009. 78 s. Dissertation consulting professor Doc. Ing. Hana Ezrová, CSc.. The work considers using marketing directing in a specific company. Specific resources and solutions are used, and based on them a description and analysis of marketing directing in company LINE, s.r.o. was made. This project is divided into two parts, the first is created as a general frame for the use of marketing directing and the second part is the application part, with definition of company and subsequent analysis of each steps of marketing directing. The conclusion contains recommendations connected with the world financial crisis.
|
| |
|
Solution of optimization problems with non-decreasing constraints.
Pavlíček, Ondřej ; Zimmermann, Karel (advisor) ; Palata, Jan (referee)
The content of this work is a presentation of algorithms solving optimization problems with a max-separable objective function of the form f(x) = maxjJ fj (xj), where fj are continuous unimodal functions. The optimization problems are solved under constraints, which are described by a system of (max,+)-linear equations and inequalities with variables occurring on both sides of the constraints. In Chapter 6, a modification of this problem with different variables on each side of the constraints is studied. Chapter 7 deals with problems, in which the constraint coefficients may be infinite. The work is based on results contained in previous publications, in which was shown that if the set of feasible solutions of the optimization problems considered here is nonempty, it has always the greatest element. The algorithms suggested in this work begin with this greatest element and decrease step by step the objective function without leaving the feasible set. The method proceeds in a certain sense by analogy with the method of feasible directions. Proofs of correctness of the algorithms and some results concerning computational complexity, as well as a computer implementation are included in the concluding part of the work.
|
|
Politicians´ Interest in the Views of Citizens and Citizens' Ability to Influence the Public Sphere - February 2017
Černá, Lucie
In its regular February survey Public Opinion Research Centre further examined whether people think that politicians are interested in the views of citizens, and whether in the opinion of the Czech public, people have certain opportunities to influence the public sphere. Regarding the interest of politicians in the views of citizens, the vast majority (82%) of the Czech public thinks that only minority of Czech politicians is interested in people's opinion. 14% of the population believe that in the views of citizens is interested none of Czech elected politicians. Within the possibilities to influence the public sphere has occurred shift in a positive direction in all researched spheres, which is the most evident in the area of solving problems in respondents’ village or town. Also assessing the potential to influence public sphere is in all analyzed aspects related to the assessment of living standards of respondent's household, while people with good living standards are more likely to feel they can influence public sphere.
|
|
The thermal regime of ice pits of the Borec hill
Türkott, L. ; Martinčíková, Eva ; Potop, V.
The ecological stability of the sites with stenoec organisms is important factor for maintaining them at given location. Phonolite system of the Borec hill creates a unique labyrinth of vents. Thermal anomalies occur during the year in the fissure system and create specific microclimate. Flow direction is given by the temperature gradient inside and outside of the system. The lower part of fissure system is located in the debris fields, while the upper part on top of the hill. Phonolite rocks are cooled down by air streaming from the debris fields during the winter. Direction of the air flow changes in the spring and summer. The cold air is exhaled from these vents on the lower parts of system and creates ice pits with the typical vegetation.
|
|
On the recirculation zone suppression behind HUMP profile using the DBD actuator
Procházka, Pavel P. ; Uruba, Václav
Previously, the DBD (dielectric barrier discharge) plasma actuator was used in rectangular channel to modify the properties of the boundary layer in spanwise and in streamwise orientation. The actuator was redesigned for using on the surface of the Glauert-Goldschmied body in different position to influence the point of the separation and the reattachment point as well as the total extent of the separation bubble. The most intensive effect occurs when the actuator takes effect in the point of separation. Further downstream, the ionic wind produced by DBD causes complex coherent structures in the wake for spanwise orientation in both direction. The effect of streamwise orientation is studied also. Actuator is operated in steady regime to produces continuous ionic wind as well as in unsteady regime when the vortex street is generated. The properties of vortex street is given by modulation parameters (frequency and duty cycle). The effect of these parameters on the wake is evaluated. This experiment is realized in the perspex channel connected to the blow-down wind tunnel. The HUMP profile is flush-mounted to the bottom side. The wire electrode of the actuator is situated in x/L = 0.63, 0.66, 0.69 and 0.72 of the chord length. The time-resolved PIV (Particle Image Velocimetry) is used as a main measurement technique. The flow field behind the profile is captured in longitudinal plane as well as in cross-section planes using 3D PIV. The results based on statistical quantities will be presented in this paper. More, next part will be devoted to the decomposition analysis of the flow dynamics (BOD, OPD).
|
guest ::
